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Top Picks — Antioxidant

🛡️ Best Antioxidant Supplements

Polyphenols, vitamins, and free radical scavengers studied for cellular protection, oxidative stress reduction, and aging defense.

194 ingredients reviewed Ranked by clinical evidence

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Top 5 — Ranked by Evidence

Antioxidant Properties

250–500 mg/day EGCG standardized extract; whole green tea: 3–5 cups/day (≈240–320 mg

Antioxidant enzymes and oxidative stress markers

Heart failure: 100 mg 3×/day; migraine: 100-300 mg/day; statin muscle symptoms: 100-600 mg/day; all from trials in diagnosed conditions. Take with a fatty meal.

Oceanix™ (Marine Phytoplankton — Lonza)

Antioxidant enzyme gene expression in muscle

Per Lonza product specification (typically 25 mg/day Oceanix)

Pycnogenol® (French Maritime Pine Bark)

Oxidative stress markers

50–200 mg/day; cardiovascular: 100–200 mg/day; cognitive: 100 mg/day; athletic perfor

Lower Oxidative Stress Markers in Blood

8 to 11 mg/day elemental zinc is the adult RDA; supplements provide 15 to 30 mg/day.

📈 Fastest Growing Antioxidant Ingredients

Branded ingredients seeing rapid growth in formulator adoption and clinical research in 2024–2026.

Hytolive® (Olive Fruit Polyphenols / Hydroxytyrosol)

Less LDL oxidation in a 16-week placebo-controlled trial

15 mg of hydroxytyrosol per day as Hytolive capsules for 16 weeks in the only…

Quercefit® (Quercetin Phytosome — Indena)

Antioxidant and Anti-Inflammatory Action

250 to 500 mg/day, about 100 to 200 mg quercetin, in the studies; the 1,000 mg/day senolytic…

🔬 Future Antioxidant Ingredients to Watch

Lower current evidence but active research underway — these may become top picks within 2–3 years.

R-Lipoic Acid (Natural / Stabilized R-ALA)

Antioxidant Activity (Both Water and Lipid Soluble)

Products typically supply 100-300 mg/day of R-ALA. The cited studies gave only single…

CyaniMax® (Cyanidin-3-O-Glucoside Anthocyanin — BGG World)

C3G anthocyanin with laboratory antioxidant activity

300 mg/day (black soybean hull extract / C3G).

GlyNAC (Glycine + N-Acetylcysteine)

Oxidative stress markers (TBARS, F2-isoprostanes)

100 mg/kg/day each of glycine and NAC (about 7 g of each for a 70 kg adult) for 16 weeks in…

Recommended Antioxidant Products

Heads up: NutraSmarts may earn a commission from purchases made through these links, at no extra cost to you. We curate these picks based on the same evidence we cite throughout the page. Full disclosure.

Real products featuring the best-evidenced antioxidant ingredients ranked above - chosen for clinically-studied forms and doses, third-party testing, and value. Match the supplement to your specific need.

Best for daily antioxidant & immune support Amazon →

NOW Foods Vitamin C-1000 Sustained Release with Rose Hips

1,000 mg sustained-release tablets, 250 ct

Sustained-release tablet spreads vitamin C delivery over hours, with rose hips bioflavonoids; non-GMO, GMP-assured.

Best for circulation & skin antioxidant support Amazon →

Healthy Origins Pycnogenol 100 mg

100 mg veg capsules, 60 ct

Uses branded French maritime pine bark Pycnogenol, one of the most clinically studied antioxidant extracts.

Best for skin & eye antioxidant support Amazon →

Sports Research Triple Strength Astaxanthin 12 mg

12 mg softgels with coconut oil, 60 ct

Algae-sourced astaxanthin paired with coconut oil to aid absorption of this fat-soluble carotenoid; non-GMO verified.

Best for cellular energy & heart antioxidant support Amazon →

Doctor's Best High Absorption CoQ10 with BioPerine

100 mg softgels, 120 ct

Naturally fermented CoQ10 with BioPerine to enhance absorption; non-GMO, gluten-free, generous 120-count.

All Antioxidant Ingredients (194)

Antioxidant Properties

250–500 mg/day EGCG standardized extract; whole green tea: 3–5 cups/day (≈240–320 mg

Antioxidant enzymes and oxidative stress markers

Heart failure: 100 mg 3×/day; migraine: 100-300 mg/day; statin muscle symptoms: 100-600 mg/day; all from trials in diagnosed conditions. Take with a fatty meal.

Oceanix™ (Marine Phytoplankton — Lonza)

Antioxidant enzyme gene expression in muscle

Per Lonza product specification (typically 25 mg/day Oceanix)

Pycnogenol® (French Maritime Pine Bark)

Oxidative stress markers

50–200 mg/day; cardiovascular: 100–200 mg/day; cognitive: 100 mg/day; athletic perfor

Lower Oxidative Stress Markers in Blood

8 to 11 mg/day elemental zinc is the adult RDA; supplements provide 15 to 30 mg/day.

Antioxidant defense and glutathione support

75–90 mg/day (RDA); immune/antioxidant: 200–500 mg/day; upper limit 2,000 mg/day; lip

Alpha Lipoic Acid

Antioxidant support: lower oxidative stress markers

DIABETIC NEUROPATHY: 600 mg/day racemic ALA (SYDNEY 2 + NATHAN 1). T2DM IR: 300 mg/da

Oxidative stress markers in human trials

4 to 12 mg/day of astaxanthin from Haematococcus pluvialis; take with a fat-containing meal.

AstaZine® (Natural Astaxanthin from Haematococcus pluvialis — BGG)

Mildly lower oxidative stress marker (MDA) in placebo-controlled trials

4-12 mg/day AstaZine (research-validated; some applications 12-24 mg)

Grape Seed Extract (OPC)

Antioxidant activity in blood markers

100–400 mg/day standardized extract (≥95% OPCs); blood pressure: 150–300 mg/day MegaN

Mixed Tocopherols (Naturally Sourced Vitamin E — Cargill)

Antioxidant Activity

Varies by application; antioxidant supplementation typical 100-400 IU vitamin E

NAC (N-Acetylcysteine)

Antioxidant Support

600–1,800 mg/day in divided doses; respiratory: 600 mg twice daily; liver support: 60

Pine Bark Extract

Antioxidant activity

Standard dose: 100-300 mg/day standardized pine bark extract (≥85% proanthocyanidins)

Propolis (Bee Propolis)

Antioxidant status in blood tests

About 1,000 mg/day (500 mg twice daily) in a 90-day trial of 94 adults with type 2

Selenomethionine

Antioxidant enzyme glutathione peroxidase in low-selenium adults

100-200 µg elemental selenium/day; Hashimoto's trials typically 200 µg/day

Truebroc® (Glucoraphanin Broccoli Seed Extract — Brassica Protection Products)

Antioxidant enzymes and other markers in broccoli studies (not Truebroc®)

30-150 mg/day (providing 4-20 mg glucoraphanin) is the usual supplement range; the cited studies used other broccoli sprout preparations, so their doses do not map onto these numbers.

Antioxidant protection

15 mg/day (RDA); therapeutic studies use 400–1,000 IU/day

Amla (Indian Gooseberry)

Improved oxidative stress markers in one type 2 diabetes trial

The hyperlipidemia trial used 500 mg/day for 42 days; the diabetes trial used 250 mg or 500 mg of Capros twice a day for 12 weeks. There is no established dose for healthy consumers.

AroniaPURE® (Chokeberry Powder)

Antioxidant defense

Commonly around 300 mg to 2 g of aronia per day.

AstaReal® Astaxanthin

Lower oxidative stress markers

Commonly 4 to 12 mg of astaxanthin per day.

Oxidative stress markers: lower MDA, higher antioxidant capacity

5 mL of oil a day in a honey formulation for 8 weeks, as studied in functional

Curcumin/Turmeric

Antioxidant Protection

About 1,000 to 1,500 mg/day of standardized extract in divided doses; plain turmeric powder is only 2 to 5% curcuminoids, so the raw spice is not equivalent.

Eye-Pro MD® (Lutein, Zeaxanthin and Meso-Zeaxanthin)

Antioxidant protection

Commonly 10 mg lutein with zeaxanthin and meso-zeaxanthin per day.

L-OptiZinc® (Zinc Mono-L-Methionine — Lonza)

Antioxidant Defense (Cofactor for SOD)

10-30 mg elemental zinc/day (per L-OptiZinc product specification)

Lutemax® Lutein Esters (Marigold Lutein Esters)

Antioxidant protection

Commonly 10 to 20 mg lutein with 2 to 4 mg zeaxanthin per day.

OptiLut® (Lutein and Zeaxanthin)

Antioxidant protection

Commonly 10 to 20 mg lutein with 2 to 4 mg zeaxanthin per day.

P40p™ (Pomegranate Extract — PLT Health)

Antioxidant defense

Per the product specification.

Pomegranate Extract

Antioxidant capacity

Standard cardiovascular dose: 500-1,500 mg/day pomegranate extract standardized to ≥3

Punicalagins (Pomegranate Polyphenols)

Antioxidant status: higher TAC, lower MDA in pomegranate trials

POMEGRANATE JUICE: 240 mL/day = ~318 mg punicalagins. POMx: 1000 mg/day. STANDARDIZED

Carotenoid and vitamin E antioxidants

Used as a cooking fat. In pooled trials up to about 8 g/day raised blood vitamin A;

Antioxidant defense

55 mcg/day (RDA); therapeutic studies: 100–200 mcg/day; upper limit 400 mcg/day

Selenium Yeast (High-Selenium Yeast)

Antioxidant enzyme support when selenium is low

100-200 µg of elemental selenium a day is the range used in research; the adult tolerable upper limit is 400 µg a day, and 300 µg a day for five years was linked to increased mortality.

Ubiqsome® (Coenzyme Q10 Phytosome — Indena)

Antioxidant Activity

100-300 mg/day Ubiqsome (CoQ10 equivalent)

Zanthin® (Natural Astaxanthin — Valensa International)

Antioxidant markers in the blood

Commonly 4 to 12 mg of astaxanthin per day.

Glutathione Precursor

500–1,500 mg/day for hair/skin support; for glutathione support, NAC (600–1,200 mg/da

Antioxidant activity — strongest mechanistic story

8-21 mg/day food or supplement. CV/prostate: 15-45 mg/day. Bone (LycoRed): 8 mg/day.

Turkey Tail Mushroom

Antioxidant protection

1–3 g/day PSK extract; 2–9 g/day whole mushroom powder

Glutathione (Reduced L-Glutathione)

Raising the body's glutathione stores over months

250 to 1,000 mg/day of reduced glutathione, taken for 4 weeks to 6 months; 250 mg/day,

Jabuticaba (Plinia cauliflora)

Blood Antioxidant Capacity

Jaboticaba peel powder 7 to 15 g a day (7 g supplies about 225 mg polyphenols,

Argan Oil (Argania spinosa, Edible)

Oxidative stress markers and LDL resistance to oxidation

About 25 mL (roughly 25 g) a day of virgin argan oil, taken at breakfast in place of

Exceptional antioxidant capacity

200 g pulp/day for 30 days; 200 mL juice/day for 4 weeks; a single 7 mL/kg dose; 40 g/day dehydrated acai for 7 days. Powder and capsule doses vary and were not tested in the cited studies.

Broccoli Extract (Glucoraphanin)

Oxidative Stress Markers

Glucoraphanin: 30-100 mg/day with myrosinase. Sulforaphane: 10-50 mg/day. ASD trials:

Superior antioxidant effect vs isolated vitamin C

70 mL of 100% camu camu juice per day (about 1,050 mg vitamin C) for 7 days is the only tested dose; powder supplements at 100-500 mg per day are far smaller and untested.

GlyNAC (Glycine + N-Acetylcysteine)

Oxidative stress markers (TBARS, F2-isoprostanes)

100 mg/kg/day each of glycine and NAC (about 7 g of each for a 70 kg adult) for 16 weeks

Molecular Hydrogen (H2)

Selective radical scavenging (shown in cells and rats)

Oral hydrogen-rich water, about 11 mg H2/day (one tablet in 250 mL, three times daily) in the 24-week metabolic syndrome trial; other cited trials used 3.5 mg/day and 7.5 mg/day.

Watercress (Nasturtium officinale)

Supports blood antioxidant status and carotenoid levels

In trials, 85 g of raw watercress a day for 8 weeks (DNA-damage crossover) and about

Aronia / Chokeberry (Aronia melanocarpa)

Antioxidant Enzyme Support

STANDARDIZED EXTRACT: 100-300 mg/day (25-50 mg anthocyanins) OR juice 200-300 mL/day

CyaniMax® (Cyanidin 3-Glucoside — BGG)

C3G anthocyanin with laboratory antioxidant activity

Per BGG CyaniMax product specification

DeltaGold® (Annatto Tocotrienols — American River Nutrition)

Lower oxidative stress markers versus placebo in two trials

DeltaGold 70 at 430 or 860 mg/day (300 or 600 mg tocotrienol) for 12 weeks; annatto

Isoquercitrin (Isoquercetin, Quercetin-3-O-glucoside)

Blood markers of oxidative stress

42 mg/day EMIQ in protein powder; 100 mg EMIQ capsules in pollen season trials; 200 to

Kale (Brassica oleracea var. acephala)

Antioxidant enzyme activity and oxidative stress markers

150 mL a day of kale juice for 12 weeks in the men's cholesterol study; 300 mL a day

Lemon Verbena (Aloysia citrodora)

Exercise-related oxidative stress markers

400 mg/day of standardized leaf extract in the sleep, stress and exercise trials (1

Leucoselect® Phytosome (Grape Seed Phytosome — Indena)

Antioxidant Activity

100-300 mg/day Leucoselect Phytosome (research-validated)

Limosilactobacillus fermentum (Lactobacillus fermentum)

Blood antioxidant markers in healthy adults (strain ME-3)

Strain-specific: 1 x 10^9 to 1.26 x 10^10 CFU/day of VRI-003 (PCC) in athletes; 1 x

Antioxidant support, with mixed human results

2–7 g/day leaf powder; clinical studies typically use 6–8 g/day

Papaya (Carica papaya)

Source of antioxidant vitamin C, carotenoids and polyphenols

By preparation. Fermented papaya preparation: 6 to 9 g a day for 3 to 14 weeks in

Prickly Pear Cactus (Opuntia ficus-indica)

Lower markers of oxidative stress with the fruit

Depends on the plant part: about 300 g cooked nopal pads with a meal; pad fiber 3 g a

Quercefit® (Quercetin Phytosome — Indena)

Antioxidant and Anti-Inflammatory Action

250 to 500 mg/day, about 100 to 200 mg quercetin, in the studies; the 1,000 mg/day senolytic figure comes from trials pairing quercetin with a prescription drug, not tested for this product.

Rosa roxburghii (Chestnut Rose / Cili Fruit)

Higher plasma antioxidant capacity in a controlled feeding study

Antioxidant feeding study: an encapsulated fruit supplement daily for 5 weeks. Immune

Setria® Glutathione

Raises glutathione levels in blood and body cells

250–500 mg/day; 250 mg shown effective for increasing blood glutathione levels

Spectra® (30-plant antioxidant blend — FutureCeuticals)

Broad antioxidant support

100 mg single oral dose (capsule) in the published human crossover studies

Yerba Mate (Ilex paraguariensis)

Blood antioxidant capacity in longer mate tea trials

3 g a day of yerba mate capsules for 12 weeks in the cited body fat trial (the

Skin oxidative stress markers after UV exposure

6–20 mg/day; AREDS2: 10 mg/day lutein + 2 mg zeaxanthin; eye health: 10–20 mg/day wit

AstaSana™ (Natural Astaxanthin)

Antioxidant activity

Commonly 4 to 12 mg of astaxanthin per day.

Barberry Fruit (Berberis vulgaris)

Antioxidant balance markers in blood

10 g/day of milled dried fruit for 8 weeks; 600 mg/day of dried barberry capsules for

Barley Grass (Young Barley Leaf)

Supports antioxidant defenses, based on short trials

Leaf powder 1.5-3 g per serving; concentrated leaf powder 8 g/day plus tablets; leaf

Betalains (Beetroot Pigments)

Antioxidant activity, mostly measured in the test tube

BEETROOT JUICE: 250-500 mL/day (~5-10 mmol nitrate + 30-100 mg betalains). FREEZE-DRI

Bilberry (Vaccinium myrtillus)

Blood antioxidant markers

240 mg/day for 12 weeks or 480 mg/day for 8 weeks of extract for eye strain after

BioTurmin® (Bioavailable Turmeric)

Antioxidant defense

Commonly 500 to 1000 mg of curcuminoids per day.

Blood Orange Extract (Moro Red Orange, Citrus sinensis)

Antioxidant markers in blood and skin

Moro extract (Morosil) 400 mg/day for 12 weeks to 6 months for weight; three-variety

BroccoRaphanin® (Broccoli Seed Glucoraphanin)

Antioxidant defense

Commonly providing tens of milligrams of glucoraphanin per day.

Burdock Root (Arctium lappa)

Antioxidant enzyme activity and oxidative stress markers

Not established. Human trials used 6 g of dried root a day as three cups of tea (2 g

Clove (Syzygium aromaticum)

Oxidative stress markers during an alcohol challenge

250 mg once a day of a clove bud polyphenol extract (Clovinol) in every human study:

Clovinol® (Clove Bud Extract for Metabolic — Akay Bioactives)

Oxidative stress markers during an alcohol challenge

250 mg once a day in every human study: one capsule around a single alcohol challenge,

Cosmythic® (Maritime Pine Bark for Skin — Purextract)

Antioxidant defense

Commonly around 50 to 100 mg per day.

Curcumin C3 Reduct® (Tetrahydrocurcuminoids — Sabinsa)

Antioxidant defense

Commonly around 150 to 600 mg per day.

CurcuZen® (95% Curcuminoid Turmeric Extract — Bioactives American)

Antioxidant status in curcumin trials

Commonly 500 to 1000 mg of curcuminoids per day.

Enzogenol® (Pinus radiata Bark Extract)

Oxidative stress markers in chronic smokers

Cognitive: 480 mg/day × 5 weeks. Mild TBI: 1,000 mg/day × 6-12 weeks. Take with food.

Ergothioneine (ErgoActive®)

Antioxidant protection

5–30 mg/day; most human studies use 5–20 mg/day; dietary intake from mushrooms typica

Antioxidant activity in vivo

Hyperlipidemia: 1,000 mg/day × 6 weeks (the best-studied protocol). Asian clinical do

Glabridin (Licorice Isoflavone)

LDL oxidation reduction (6-month trial)

Licorice-root extract with ~60 mg/day glabridin (LDL oxidation); licorice flavonoid oil 300–900 mg/day (body fat). No established pure-glabridin human dose.

Hytolive® (Olive Fruit Polyphenols / Hydroxytyrosol)

Less LDL oxidation in a 16-week placebo-controlled trial

5–20 mg/day hydroxytyrosol (as Hytolive®); EU health claim: ≥5 mg/day hydroxytyrosol

Mangosteen Pericarp (Garcinia mangostana)

Antioxidant capacity in the blood

Extracts: 400 mg/day standardized to 40% mangostins for 26 weeks, 1,000 mg/day (2 x

Marjoram (Origanum majorana)

Antioxidant enzymes and protein oxidation with daily marjoram tea

Marjoram tea from tea bags, two 250 mL cups daily for 1 month (hormone trial);

MitoQ (Mitoquinone)

Lower oxidized LDL, an oxidative stress marker

ROSSMAN 2018 VASCULAR: 20 mg/day × 6 wk endothelial function. PD PHASE II: 40-80 mg/d

Natavid® (Whole Grapevine Extract — Natac)

Antioxidant defense

Per the product specification.

Nutroxsun® (Rosemary and Grapefruit Extract — Monteloeder)

Lower oxidative damage marker in the skin

100 to 250 mg/day taken daily; the single trial tested both doses and found no difference between them.

Antioxidant via metabolite effects

Human trials used whole strawberries: about 250 to 500 g fresh, or 10 to 50 g of freeze-dried powder per day; there is no established dose for purified pelargonidin itself.

Phyto-C® (whole-food vitamin C and polyphenol immune complex — FutureCeuticals)

Helps protect cells from oxidative stress

150 mg/day of the finished whole-food blend; acerola supplies the natural vitamin C.

Phytoene and Phytofluene (Colorless Carotenoids)

UV-exposed skin markers of oxidative stress

Taken by mouth as part of tomato nutrient complexes. One UVB trial used about 5.8

Piceatannol (Passion Fruit Stilbene)

Antioxidant and free radical scavenging activity

Human trials used 5 to 100 mg a day of piceatannol from passion fruit seed extract for

Pomella® (Pomegranate Extract — Verdure Sciences)

Antioxidant biomarker enhancement

Standard cardiovascular protocol: 500-1,500 mg/day Pomella® standardized extract. Mos

Red Orange Complex® (Sicilian Red Orange Extract — Bionap)

Antioxidant balance in the blood

100 mg a day, one capsule after breakfast, for 56 days in the skin trial and 8 weeks

S7® (plant-based nitric oxide booster — FutureCeuticals)

Antioxidant support against everyday free radicals

25–50 mg once daily (50 mg used in the main RCT and the 230% NO pilot)

Schisandra Chinensis (Five-Flavor Berry)

Antioxidant and Anti-Inflammatory

1,000 mg/day of extract in both muscle-strength trials, within a common commercial range of 500-2,000 mg/day; berry powder 1-6 g/day.

Sulforaphane / Glucoraphanin

NRF2 and glutathione-linked protective enzymes

Standard supplementation: 60-150 mg glucoraphanin with active myrosinase (provides 10

Sumac (Rhus coriaria)

Antioxidant capacity and lipid oxidation markers in blood

1 to 3 g/day of sumac fruit powder in capsules: 500 mg twice daily for 6 weeks, 500 mg

Tart Cherry Extract

Antioxidant capacity

Recovery: two 8 oz servings of tart cherry juice a day, or 30 mL of concentrate twice a day; sleep: 30 mL of concentrate twice a day. No cited study tested a capsule dose in milligrams.

Terminalia Chebula (Rejuna®)

Oxidative-stress markers in a 12-week placebo-controlled trial

500–1,000 mg/day of standardized aqueous fruit extract, given as 250–500 mg twice daily, the range used in the human trials. Traditional whole-fruit powder use is higher, around 3–5 g/day.

Wheatgrass (Young Wheat Leaf)

Antioxidant pigments and vitamins in the fresh grass

Fresh juice 60-100 mL/day; tablets of dried powder, 12/day of unstated strength, in

Xanthohumol (Hop Chalcone, Humulus lupulus)

Protection of white blood cell DNA from oxidative damage

24 mg/day for 8 weeks in the two safety trials; single doses of 20 to 180 mg in

Amlaac® (Amla / Indian Gooseberry Extract)

Lower oxidative stress markers in trials of another amla extract

Commonly around 500 mg to 1 g per day of amla extract. The pooled meta-analysis used various doses and preparations, and no Amlaac®-specific dose has been established in a trial.

Asta-Marine® (Marine Astaxanthin)

Antioxidant power

Commonly 4 to 12 mg of astaxanthin per day.

AstaBead® (Astaxanthin Beadlet)

Blood oxidative stress markers: mild, variable drops in astaxanthin trials

Commonly 4 to 12 mg of astaxanthin per day.

Baobab Fruit Powder (Adansonia digitata)

Antioxidant Activity

Commonly used at 5 to 15 g/day of baobab fruit powder, but the human studies did not test a daily powder dose; they used 18.5 to 37 g of concentrated aqueous extract or a single 250 mL drink.

CaroCare® (Natural Beta-Carotene — DSM)

Antioxidant defense

Commonly providing a few milligrams of beta-carotene per day.

Carotex® (Natural Beta-Carotene and Carotenoids — Zeus Hygia)

Vitamin A and antioxidant support

Typical carotenoid supplements supply a few milligrams per day; the cited trial did not name Carotex or state a dose, so treat this as a general range, not a studied dose.

Cordiart® (Tomato Nutrient Complex)

Antioxidant defense

Providing about 15 to 30 mg of lycopene per day.

EllagiRush® (Pomegranate Extract — Arjuna)

Antioxidant defense

No established dose for EllagiRush, since no trial has used it; the cited human trial used pomegranate juice, not a measured extract dose.

EVNol® (Palm Tocotrienol and Tocopherol Complex — ExcelVite)

Oxidative-damage markers in blood

The trials used 200 mg of mixed tocotrienols twice a day, 400 mg/day total, for 1 to 2 years, delivered as a self-emulsifying softgel rather than plain tocotrienol oil.

Luravida® (Cranberry Omega-3 Oil — AHD International)

Antioxidant Activity

Per AHD Luravida product specification (typical 1-3 g/day)

Masquelier's® French Pine Bark (OPCs)

Antioxidant defense

Commonly 100 to 200 mg per day.

Masquelier's® Original OPCs

Antioxidant defense

Commonly 100 to 200 mg per day.

Melostacio® (Mango Leaf Extract)

Anti-inflammatory and antioxidant protection

150 mg/day of mangiferin for 12 weeks in the only human trial, generic and not Melostacio; no published trial has tested Melostacio itself.

MintyBright™ Nu

Antioxidant defense support

150 mg/day for 12 weeks

NeuGrape® (Grape Seed Extract, 95% OPCs)

Lower oxidation markers in blood

No dose of NeuGrape has been tested in a published study; the one cited study used 100 mg/day of ActiVin, a different company's grape seed extract.

PhytoPin® (French Maritime Pine Bark Extract)

Antioxidant defense

Commonly 100 to 200 mg per day.

Anti-Inflammatory / Antioxidant

50-250 mg/day; trial used 125 mg twice daily (250 mg/day total)

Reishi Mushroom

Antioxidant protection

1.5–9 g/day whole mushroom powder; 1–1.5 g/day standardized extract

Antioxidant/singlet oxygen quenching (mechanistic)

CV: 860 mg/day × 20 wk hypercholesterolemia. STRANDBERG 1990: 900 mg/day. PK: 500 mg

Tocotrienols (Vitamin E Family)

Antioxidant Activity (Distinct from Tocopherols)

100-400 mg/day total tocotrienols; for cholesterol/CV: 200-300 mg gamma+delta tocotri

Vitaflavan® (Grape Seed Extract)

Antioxidant defense

Commonly 100 to 300 mg per day.

α-Lacys Reset® (Alpha-Lipoic Acid and Cysteine Complex — Nutraceutics)

Antioxidant and redox support

Used at about 25 mg per day in finished formulas, far below the 300 to 1800 mg per day alpha-lipoic acid doses in the weight-loss trials. No trial shows 25 mg reproduces those results.

Annatto (Bixa orellana)

Blood oxidation markers after one high-calorie meal

No established supplement dose. Human studies used food-color amounts: ground annatto

Epsilon-Viniferin (Grape Resveratrol Dimer)

Free radical scavenging and lower oxidative stress in laboratory studies

There is no established dose for people. One human pharmacokinetic study used a single

Isorhamnetin (Methylated Quercetin)

Antioxidant activity in laboratory and animal studies

No human dose is established. Most intake is from foods or indirectly from quercetin.

NatAxtin™ (Chilean Astaxanthin — Stratum Nutrition)

Antioxidant support during hard training

4-12 mg/day astaxanthin (typical supplemental range)

elaVida® (Olive Hydroxytyrosol — DSM)

Antioxidant status markers in one small trial

About 5 mg of hydroxytyrosol per day (the level in 20 g of extra virgin olive oil).

MitoReds™ (Mitochondrial Reds Complex)

High antioxidant capacity in laboratory testing

Per product label; typical reds blend 3–6g/day; specific MitoReds™ dosing per NNB pro

PhytoServ® (concentrated fruit & vegetable phytonutrient extract — FutureCeuticals)

Supplies natural plant antioxidants

Not established for the finished ingredient; dosed to a "1 serving" phytonutrient equivalent per label

Yaupon (Ilex vomitoria)

Chlorogenic acid and flavonol polyphenols with antioxidant activity

Consumed as a tea brewed from dried leaves, a few grams steeped in hot water. Measured

Niagen® (Nicotinamide Riboside — ChromaDex)

Oxidative stress markers in two trials

Clinical trial doses: 250-1,000 mg/day Niagen®. Most studies use 300-600 mg/day. Take

Antioxidant and Anti-Inflammatory Blood Markers

1.5 to 3 g/day in the two primary trials (500 mg three times daily; 3,000 mg/day); endurance studies used 1 to 6 g/day, with no sign larger doses worked better.

ResVinol® (Japanese Knotweed and Red Wine Resveratrol Extract — Ethical Naturals)

Antioxidant blood markers

Commonly 150 to 500 mg of trans-resveratrol per day.

AppleActiv® (Dried Apple Peel Polyphenols — Leahy Orchards)

Serum antioxidant protection

No cited study established a dose for AppleActiv. A few hundred milligrams of apple peel polyphenols per day is a typical label amount, not researched; the two cited trials fed whole apples.

Capsanthin (Paprika Carotenoid)

Antioxidant and free radical scavenging activity

No established supplement dose. Human studies used paprika sources: about 16 micromol

Dihydroquercetin (Taxifolin)

Free radical scavenging in laboratory studies

A settled human milligram dose is not established. The small older studies used a

Hepure™ (Clove & Immortelle Extract — Nexira)

Antioxidant activity of the clove and immortelle pair

No human dose of Hepure has been tested. Related human studies used 250 mg a day of a

Parsley (Petroselinum crispum)

Antioxidant enzyme activity in a controlled diet study

Food amounts only. Human studies used one serving of about 2 g blanched parsley per kg

SelectSIEVE® Olive (Olive Polyphenols — Bionap)

Antioxidant protection of LDL (olive polyphenol class evidence)

Commonly 250 to 1000 mg of olive extract per day.

TruServ® (whole-food fruit & vegetable servings — FutureCeuticals)

Supplies antioxidant phytonutrients

No dose has been studied in humans. TruServ is sold by serving-equivalence, an accounting of how much produce went into the powder, not a tested dose.

Lutemax® 2020 (Lutein + Both Zeaxanthins — OmniActive)

Raised blood antioxidant capacity

Adults: 10mg lutein+2mg zeaxanthin (low) or 20mg+4mg (high) daily. Children: 10mg+2mg

White Mulberry (Morus alba)

Lower Oxidative Stress Marker (MDA)

Reducose (5% DNJ) 200 to 500 mg just before or with a carbohydrate meal; DNJ-enriched

Antioxidant and free-radical scavenging

UCHIDA 2011 BIOAVAILABILITY: 50 mg vit C from acerola juice. COMMERCIAL: 100-500 mg p

CitrOlive® (Olive + Citrus for Cardiovascular — Frutarom)

Less LDL oxidation in one small trial

Per Frutarom CitrOlive product specification

Cumin Seed (Cuminum cyminum)

Antioxidant enzyme and oxidative stress markers

3 g/day of cumin powder in yogurt for 3 months; 50 to 100 mg/day or 75 mg three times

Curcumin C3 Complex® (Most Studied Curcumin Extract)

Antioxidant markers measured in blood

500-1,000 mg/day standardized to 95% curcuminoids; all the cited trials co-administered piperine (for example 1,500 mg curcuminoids with 15 mg piperine), so account for it.

Greenselect® Phytosome (Decaffeinated Green Tea Catechin Phytosome — Indena)

Lower plasma free radicals over 24 weeks alongside diet and exercise

300 mg/day Greenselect Phytosome, split as 150 mg twice daily (one dose before lunch,

HTEssence® (Hydroxytyrosol — Wacker)

Antioxidant markers: class evidence from natural olive hydroxytyrosol

Commonly 5 to 25 mg of hydroxytyrosol per day.

Antioxidant enzyme activity in the blood

420 mg per day of silymarin (140 mg three times daily) in cirrhosis and diabetes

Antioxidant and anti-inflammatory

DIETARY: 1-4 mg/day (walnuts, cranberries, blueberries, red wine, tea). SUPPLEMENT: 1

Antioxidant markers in olive oil trials

No trial of isolated oleocanthal. Oils: 30-40 mL with 172-621 mg/kg oleocanthal;

Phycocyanin (Spirulina Blue Pigment Extract)

Oxidative stress markers in a 12-week placebo-controlled trial

About 20 mg/day of phycocyanin (20 mL liquid extract) for 12 weeks; 250 mg to 2.3

Saberry® (Amla / Indian Gooseberry — Sabinsa)

Antioxidant Research on Amla

Per Sabinsa product specification (typical 250-500 mg/day)

SelenoForce® (Selenium-Enriched Yeast — Sabinsa)

Glutathione peroxidase antioxidant enzyme raised when selenium is low

100 to 200 mcg a day of elemental selenium; upper limit 400 mcg a day from all sources

ActiVin® (Grape Seed Proanthocyanidin Extract)

Oxidative stress marker in one uncontrolled study

Commonly 50 to 300 mg per day.

Chaga Mushroom (Inonotus obliquus)

Antioxidant Activity

500 to 2,000 mg/day of extract, or 3 to 4 g of dried chaga per cup of tea. That much dried chaga is high in oxalate, so avoid it if you have kidney disease or kidney stones.

Chrysanthemum Flower (Chrysanthemum morifolium)

Blood antioxidant markers after a high-fat meal

No established dose. Single-herb human work used a chrysanthemum extract taken once

CompleteGreens™ (Comprehensive Greens Base)

L-ergothioneine, an antioxidant the body actively absorbs

3–8g/day comprehensive greens blend; specific CompleteGreens™ dosing per NNB product

FitGrape® (Grape Polyphenol Extract)

Antioxidant defense

Product labels commonly suggest 100 to 300 mg per day; no published trial has tested FitGrape at any dose.

Raised a blood antioxidant marker in one 30-day food study

50–100 mg/day

MitoGreens® (Mitochondrial Greens Complex)

Antioxidant content and what ORAC means

MitoGreens has not been tested at any dose in a published human trial; the supplier serving is 100 mg of the blend per day.

Noni (Morinda citrifolia)

Antioxidant activity

30–750 mL/day noni juice; most studies use 29–118 mL (1–4 oz) daily; freeze-dried pow

Oli-Ola® (Olive Fruit Extract)

Antioxidant protection of LDL (hydroxytyrosol class evidence)

250 to 1000 mg of olive extract per day; the authorised antioxidant claim keys to 5 mg of hydroxytyrosol per day, so check the label for standardized hydroxytyrosol.

Purple Corn (Zea mays, Anthocyanin-Rich)

Oxidative stress markers in healthy adults

200 mg/day of freeze-dried concentrate for 3 years; a 400 mg/day cob and pandan

VinCare® (Whole Grape Extract — Ethical Naturals)

Antioxidant defense

About 350 mg per day, from the manufacturer's own materials; the only cited trial used a different product, a grape seed extract, so this dose of VinCare has not been tested here.

Eriocitrin / Eriomin® (Lemon Flavonoid)

Antioxidant and anti-inflammatory activity

200–400 mg/day Eriomin® standardized extract; blood sugar: 200 mg/day; uric acid: 200

Lutemax® Free Lutein (Marigold Lutein)

Lower oxidative stress markers in some lutein trials

Commonly 10 to 20 mg lutein with 2 to 4 mg zeaxanthin per day.

Ecklonia Cava (Brown Seaweed Polyphenol)

Antioxidant phlorotannins — laboratory assays plus one human trial

Trial doses range from 72 to 1,500 mg/day; the European Food Safety Authority set a maximum safe intake of 263 mg/day for adults, below several research doses.

Antioxidant activity (preclinical)

Traditional/clinical doses: 100-500 mg/day humic acid extract. No FDA-recognized stan

Japanese Knotweed (Polygonum cuspidatum)

Lower inflammatory markers in two small trials, oxidative stress in one

40 mg trans-resveratrol/day (200 mg of a 20% extract) in the two 6-week trials; 200 or 600 mg/day in the Gulf War Illness study. Commercial 8% extracts at 250-500 mg give 20-40 mg.

Cofactor for the antioxidant enzyme MnSOD

1.8–2.3 mg/day (AI for adults); upper limit 11 mg/day, above which intakes approach the neurotoxicity ceiling and are not established as therapeutic.

Mexidol (Ethylmethylhydroxypyridine Succinate)

Lower blood lipid peroxidation markers in small Russian trials

MIR 2024 STROKE PROTOCOL: 500 mg IV 2×/day × 10 days, then Mexidol FORTE 250 mg PO 3×

MSM (Methylsulfonylmethane)

Oxidative stress markers after hard exercise, in small trials

1-6 g/day in trials, often split into 2 or 3 doses; knee osteoarthritis trials used

Antioxidant Activity

150-500 mg/day; emerging supplement category; standardized doses not yet well-establi

Oligonol® (Lychee + Green Tea Polyphenol — Amino Up)

Oxidative stress marker MDA back near baseline sooner after exercise

Visceral fat protocol: 200 mg/day Oligonol® (50 mg twice daily) for 10 weeks. Periphe

VeriSperse® (Stabilized Astaxanthin)

Endurance and lower oxidative stress markers (10 men, generic astaxanthin)

4-12 mg/day of astaxanthin is the common range; no cited study compared VeriSperse with standard astaxanthin, so its absorption advantage is unverified here.

2-Hydroxybenzylamine (2-HOBA, Salicylamine)

Scavenges reactive dicarbonyl compounds formed during oxidative stress

Single oral doses up to 825 mg were tested in a first-in-human study. A repeated-dose

AcaiVida® (Açaí Berry Extract)

Antioxidant defense

Commonly around 1 to 2 g of açaí preparation per day.

Astrion® (NuLiv Science Beauty-From-Within)

Skin antioxidant protection

Per Astrion® product specifications; NuLiv Science beauty-from-within dosing data

AuroraBlue® (Wild Alaskan Blueberry Complex)

Antioxidant support

Commonly a few hundred milligrams of the berry complex per day, a label serving rather than a studied dose; no published human study has tested AuroraBlue at any dose.

AuroraGreen® (Wild Alaska Dandelion — Denali BioTechnologies)

Antioxidant activity in laboratory work

Per the product specification.

BerryPlus™ (Mixed Berry Antioxidant Blend — AuNutra)

Antioxidant support

No fixed clinical dose exists; BerryPlus is a customizable blend with no set composition. The one class-level maqui berry anthocyanin RCT used 162 mg anthocyanins per day for 4 weeks.

Cactinea® (Prickly Pear / Opuntia ficus-indica — Nexira)

Oxidative stress markers in a placebo-controlled prickly pear juice trial

2 g a day for 28 days in Nexira's unpublished trial in women. The published rat study

ChloroBlast® (Alfalfa Chloroplast Concentrate — Ingredients by Nature)

Antioxidant content

Per the product specification.

CocoaGanic® (Organic Cocoa Flavanols)

Oxidative stress markers in trials of cocoa in general

Products commonly provide a few hundred milligrams of cocoa flavanols per day;

E-TPGS (Water-Soluble Vitamin E)

Restores antioxidant vitamin E levels when fat absorption is poor

Per the product or formulation; no supplemental dose has been established for healthy people.

elemin® (Senonian Trace Minerals — VDF FutureCeuticals)

Trace minerals used by antioxidant enzymes (untested for elemin)

No clinical dose has been established for elemin; follow the amount stated on the

EVSpectra® (Red Palm Oil Concentrate — ExcelVite)

Red palm oil raised blood levels of antioxidant carotenoids

No trial has used EVSpectra, so there is no studied dose for this material; the human studies behind this page used very different amounts and forms.

OxiCyan® (Bilberry and Spirulina Antioxidant Complex — Biosfered)

Antioxidant defense

Commonly a few hundred milligrams per day.

R-Lipoic Acid (Natural / Stabilized R-ALA)

Antioxidant Activity (Both Water and Lipid Soluble)

Products typically supply 100-300 mg/day of R-ALA. The cited studies gave only single absorption doses (600 mg sodium R-lipoate; 50 to 600 mg racemic thioctic acid), not a daily regimen.

TraceReplace™ (plant-derived trace mineral complex — FutureCeuticals)

Minerals used by antioxidant enzymes (untested for TraceReplace)

No clinical dose has been established for TraceReplace; follow the amount stated on

TruFulvic® (Fulvic Acid from Shilajit — Natreon)

Antioxidant support

Products commonly supply about 250 to 500 mg per day, but no trial of TruFulvic has established a dose; the cited human study used 250 mg twice daily of purified whole shilajit, a different material.

VitAlign® (plant polyphenol cellular-vitality blend — FutureCeuticals)

Broad-spectrum antioxidant support

Single 50 mg oral dose; 50 mg/day (90-day metabolic study is manufacturer data)