>

Top Picks — Antioxidant

🛡️ Best Antioxidant Supplements

Polyphenols, vitamins, and free radical scavengers studied for cellular protection, oxidative stress reduction, and aging defense.

222 ingredients reviewed Ranked by clinical evidence

← All Categories

Top 5 — Ranked by Evidence

Antioxidant Properties

250–500 mg/day EGCG standardized extract; whole green tea: 3–5 cups/day (≈240–320 mg

Hytolive® (Olive Fruit Polyphenols / Hydroxytyrosol)

LDL oxidation protection (EU-authorized health claim)

5–20 mg/day hydroxytyrosol (as Hytolive®); EU health claim: ≥5 mg/day hydroxytyrosol

Antioxidant Defense and Glutathione Regeneration

75–90 mg/day (RDA); immune/antioxidant: 200–500 mg/day; upper limit 2,000 mg/day; lip

Mitochondrial antioxidant — relevant but indirect

Heart failure: 100 mg 3×/day; migraine: 100-300 mg/day; statin muscle symptoms: 100-600 mg/day; all from trials in diagnosed conditions. Take with a fatty meal.

Alpha Lipoic Acid

Universal antioxidant

DIABETIC NEUROPATHY: 600 mg/day racemic ALA (SYDNEY 2 + NATHAN 1). T2DM IR: 300 mg/da

📈 Fastest Growing Antioxidant Ingredients

Branded ingredients seeing rapid growth in formulator adoption and clinical research in 2024–2026.

Hytolive® (Olive Fruit Polyphenols / Hydroxytyrosol)

LDL oxidation protection (EU-authorized health claim)

5-20 mg/day hydroxytyrosol (as Hytolive). EU health claim: ≥5 mg/day. Cardiovascular studies:…

Mirtoselect® (Standardized Bilberry Extract — Indena)

Antioxidant and oxidative stress reduction

160-320 mg/day. Ophthalmology: 160 mg/day. Glaucoma adjunct (Mirtogenol®): 160 mg Mirtoselect…

Quercefit® (Quercetin Phytosome — Indena)

Antioxidant and Anti-Inflammatory Action

250 to 500 mg/day, about 100 to 200 mg quercetin, in the studies; the 1,000 mg/day senolytic…

🔬 Future Antioxidant Ingredients to Watch

Lower current evidence but active research underway — these may become top picks within 2–3 years.

R-Lipoic Acid (Natural / Stabilized R-ALA)

Antioxidant Activity (Both Water and Lipid Soluble)

Products typically supply 100-300 mg/day of R-ALA. The cited studies gave only single…

CyaniMax® (Cyanidin-3-O-Glucoside Anthocyanin — BGG World)

C3G anthocyanin with laboratory antioxidant activity

300 mg/day (black soybean hull extract / C3G).

GlyNAC (Glycine + N-Acetylcysteine)

Reduced oxidative-stress markers (TBARS fell in one small trial)

Glycine ~1.33 mmol/kg/day (~7 g/70 kg) + NAC ~0.83 mmol/kg/day (~9.5 g/70 kg); standard 3-6 g…

Recommended Antioxidant Products

Heads up: NutraSmarts may earn a commission from purchases made through these links, at no extra cost to you. We curate these picks based on the same evidence we cite throughout the page. Full disclosure.

Real products featuring the best-evidenced antioxidant ingredients ranked above - chosen for clinically-studied forms and doses, third-party testing, and value. Match the supplement to your specific need.

Best for daily antioxidant & immune support Amazon →

NOW Foods Vitamin C-1000 Sustained Release with Rose Hips

1,000 mg sustained-release tablets, 250 ct

Sustained-release tablet spreads vitamin C delivery over hours, with rose hips bioflavonoids; non-GMO, GMP-assured.

Best for circulation & skin antioxidant support Amazon →

Healthy Origins Pycnogenol 100 mg

100 mg veg capsules, 60 ct

Uses branded French maritime pine bark Pycnogenol, one of the most clinically studied antioxidant extracts.

Best for skin & eye antioxidant support Amazon →

Sports Research Triple Strength Astaxanthin 12 mg

12 mg softgels with coconut oil, 60 ct

Algae-sourced astaxanthin paired with coconut oil to aid absorption of this fat-soluble carotenoid; non-GMO verified.

Best for cellular energy & heart antioxidant support Amazon →

Doctor's Best High Absorption CoQ10 with BioPerine

100 mg softgels, 120 ct

Naturally fermented CoQ10 with BioPerine to enhance absorption; non-GMO, gluten-free, generous 120-count.

All Antioxidant Ingredients (222)

Antioxidant Properties

250–500 mg/day EGCG standardized extract; whole green tea: 3–5 cups/day (≈240–320 mg

Hytolive® (Olive Fruit Polyphenols / Hydroxytyrosol)

LDL oxidation protection (EU-authorized health claim)

5–20 mg/day hydroxytyrosol (as Hytolive®); EU health claim: ≥5 mg/day hydroxytyrosol

Antioxidant Defense and Glutathione Regeneration

75–90 mg/day (RDA); immune/antioxidant: 200–500 mg/day; upper limit 2,000 mg/day; lip

Mitochondrial antioxidant — relevant but indirect

Heart failure: 100 mg 3×/day; migraine: 100-300 mg/day; statin muscle symptoms: 100-600 mg/day; all from trials in diagnosed conditions. Take with a fatty meal.

Alpha Lipoic Acid

Universal antioxidant

DIABETIC NEUROPATHY: 600 mg/day racemic ALA (SYDNEY 2 + NATHAN 1). T2DM IR: 300 mg/da

Grape Seed Extract (OPC)

Antioxidant activity in blood markers

100–400 mg/day standardized extract (≥95% OPCs); blood pressure: 150–300 mg/day MegaN

Mirtoselect® (Standardized Bilberry Extract — Indena)

Antioxidant and oxidative stress reduction

160-320 mg/day Mirtoselect (manufacturer-recommended range). Standard ophthalmology d

Copper-zinc superoxide dismutase (SOD)

0.9 mg/day (RDA), 1–2 mg/day as a supplement; upper limit 10 mg/day.

Essential cofactor for the mitochondrial antioxidant enzyme MnSOD (biochemical role)

1.8–2.3 mg/day (AI for adults); upper limit 11 mg/day, above which intakes approach the neurotoxicity ceiling and are not established as therapeutic.

Antioxidant defense

55 mcg/day (RDA); therapeutic studies: 100–200 mcg/day; upper limit 400 mcg/day

Antioxidant protection

15 mg/day (RDA); therapeutic studies use 400–1,000 IU/day

Antioxidant Properties

8 to 11 mg/day elemental zinc is the adult RDA; supplements provide 15 to 30 mg/day. The upper limit is 40 mg/day; doses above it, like the 50 mg/day used in trials, need medical guidance.

Aged Black Garlic ABG10+® (Pharmactive)

Antioxidant capacity enhancement

Standard dose: 250-500 mg/day ABG10+® standardized aged black garlic extract. Cardiov

NAC (N-Acetylcysteine)

Antioxidant Support

600–1,800 mg/day in divided doses; respiratory: 600 mg twice daily; liver support: 60

Saberry® (Amla / Indian Gooseberry — Sabinsa)

Antioxidant and rejuvenative properties

Per Sabinsa product specification (typical 250-500 mg/day)

Setria® Glutathione

Increased blood and tissue glutathione levels

250–500 mg/day; 250 mg shown effective for increasing blood glutathione levels

Spectra® (30-plant antioxidant blend — FutureCeuticals)

Broad antioxidant support

100 mg single oral dose (capsule) in the published human crossover studies

Antioxidant and Anti-inflammatory Effects

1.5 to 3 g/day in the two primary trials (500 mg three times daily; 3,000 mg/day); endurance studies used 1 to 6 g/day, with no sign larger doses worked better.

BioTurmin® (Bioavailable Turmeric)

Antioxidant defense

Commonly 500 to 1000 mg of curcuminoids per day.

CitrOlive® (Olive + Citrus for Cardiovascular — Frutarom)

Strong antioxidant + anti-inflammatory activity

Per Frutarom CitrOlive product specification

CurcuZen® (Curcumin Extract)

Antioxidant defense

Commonly 500 to 1000 mg of curcuminoids per day.

Protects blood lipids from oxidation (EFSA-authorized claim)

50–100 mg/day

Mixed Tocopherols (Naturally Sourced Vitamin E — Cargill)

Antioxidant Activity

Varies by application; antioxidant supplementation typical 100-400 IU vitamin E

NatAxtin™ (Chilean Astaxanthin — Stratum Nutrition)

Powerful Antioxidant Activity

4-12 mg/day astaxanthin (typical supplemental range)

Pine Bark Extract

Antioxidant activity

Standard dose: 100-300 mg/day standardized pine bark extract (≥85% proanthocyanidins)

Antioxidant Activity (laboratory only)

500-1,000 mg/day; in pooled blood pressure trials 500 mg/day or more worked while doses below 500 mg/day did nothing, and many products supply well under 500 mg.

Antioxidant capacity enhancement (vitamin E sparing)

BP: 60 mg/day × 4 wk hypertensive. LIPID: 200-247 mg/day (Wu 2006: 50 g/d seed). 20-H

AroniaPURE® (Chokeberry Powder)

Antioxidant defense

Commonly around 300 mg to 2 g of aronia per day.

AstaReal® Astaxanthin

Antioxidant power

Commonly 4 to 12 mg of astaxanthin per day.

Bilberry (Vaccinium myrtillus)

Antioxidant protection and anti-inflammatory activity

80–480 mg/day standardized extract (25% anthocyanosides = 20–120 mg anthocyanins); ey

Chlorogenic Acid

Antioxidant activity in the body

BP: 140 mg/day green coffee bean × 4 wk. WEIGHT: 500 mg/day GBCE ≥30% CGA → -1.30 kg

Coffee Fruit Extract (CoffeeFruit Pure™)

Antioxidant and neuroprotection

100–200 mg/day whole coffee fruit concentrate; NeuroFactor™ clinical dose: 100 mg/day

CognatiQ® (whole coffee fruit extract for BDNF & cognition — FutureCeuticals)

Provides coffee-fruit polyphenol antioxidants

100 mg in the acute BDNF and cognition studies; commonly marketed at 100–200 mg/day

Curcumin/Turmeric

Antioxidant Protection

About 1,000 to 1,500 mg/day of standardized extract in divided doses; plain turmeric powder is only 2 to 5% curcuminoids, so the raw spice is not equivalent.

Eye-Pro MD® (Lutein, Zeaxanthin and Meso-Zeaxanthin)

Antioxidant protection

Commonly 10 mg lutein with zeaxanthin and meso-zeaxanthin per day.

EyeMuse® (Lutein and Zeaxanthin for Vision)

Antioxidant protection

Commonly 10 to 20 mg lutein with 2 to 4 mg zeaxanthin per day.

L-OptiZinc® (Zinc Mono-L-Methionine — Lonza)

Antioxidant Defense (Cofactor for SOD)

10-30 mg elemental zinc/day (per L-OptiZinc product specification)

Lutemax® Free Lutein (Marigold Lutein)

Antioxidant protection

Commonly 10 to 20 mg lutein with 2 to 4 mg zeaxanthin per day.

Lutemax® Lutein Esters (Marigold Lutein Esters)

Antioxidant protection

Commonly 10 to 20 mg lutein with 2 to 4 mg zeaxanthin per day.

Antioxidant Properties

The efficacy of these mechanisms depends on silymarin content (standardized extracts

Oceanix™ (Marine Phytoplankton — Lonza)

Indirect antioxidant via SOD enhancement

Per Lonza product specification (typically 25 mg/day Oceanix)

OptiLut® (Lutein and Zeaxanthin)

Antioxidant protection

Commonly 10 to 20 mg lutein with 2 to 4 mg zeaxanthin per day.

P40p™ (Pomegranate Extract — PLT Health)

Antioxidant defense

Per the product specification.

Polypodium Leucotomos

Antioxidant Support

Typically dosed at 240–480 mg/day

Pomegranate Extract

Antioxidant capacity

Standard cardiovascular dose: 500-1,500 mg/day pomegranate extract standardized to ≥3

Sea Buckthorn (Hippophae rhamnoides)

Vitamin C and Antioxidant Source

1-3 g/day sea buckthorn oil (berry pulp or seed oil); berry powder 5-10 g/day; vitami

Sulforaphane / Glucoraphanin

NRF2 activation (master antioxidant response)

Standard supplementation: 60-150 mg glucoraphanin with active myrosinase (provides 10

Ubiqsome® (Coenzyme Q10 Phytosome — Indena)

Antioxidant Activity

100-300 mg/day Ubiqsome (CoQ10 equivalent)

Zanthin® (Natural Astaxanthin)

Antioxidant power

Commonly 4 to 12 mg of astaxanthin per day.

Antioxidant Properties

2–10 mg/day; AREDS2 formula uses 2 mg zeaxanthin + 10 mg lutein; combined lutein/zeax

AstaBead® (Astaxanthin Beadlet)

Antioxidant activity, mostly lab-based

Commonly 4 to 12 mg of astaxanthin per day.

Glutathione Precursor

500–1,500 mg/day for hair/skin support; for glutathione support, NAC (600–1,200 mg/da

Antioxidant activity — strongest mechanistic story

8-21 mg/day food or supplement. CV/prostate: 15-45 mg/day. Bone (LycoRed): 8 mg/day.

Turkey Tail Mushroom

Antioxidant protection

1–3 g/day PSK extract; 2–9 g/day whole mushroom powder

Exceptional antioxidant capacity

200 g pulp/day for 30 days; 200 mL juice/day for 4 weeks; a single 7 mL/kg dose; 40 g/day dehydrated acai for 7 days. Powder and capsule doses vary and were not tested in the cited studies.

Superior antioxidant effect vs isolated vitamin C

70 mL of 100% camu camu juice per day (about 1,050 mg vitamin C) for 7 days is the only tested dose; powder supplements at 100-500 mg per day are far smaller and untested.

GlyNAC (Glycine + N-Acetylcysteine)

Reduced oxidative-stress markers (TBARS fell in one small trial)

PIVOTAL: glycine 1.33 mmol/kg/day (~7 g/70 kg) + NAC 0.83 mmol/kg/day (~9.5 g/70 kg)

Antioxidant Activity

Every human trial of isolated kaempferol used 10 mg, the highest ever 50 mg/day; commercial 50 to 200 mg capsules have never been tested, and there is no established clinical dose.

MitoReds™ (Mitochondrial Reds Complex)

Best-in-class reds antioxidant power

Per product label; typical reds blend 3–6g/day; specific MitoReds™ dosing per NNB pro

Molecular Hydrogen (H2)

Selective radical scavenging (shown in cells and rats)

Oral hydrogen-rich water, about 11 mg H2/day (one tablet in 250 mL, three times daily) in the 24-week metabolic syndrome trial; other cited trials used 3.5 mg/day and 7.5 mg/day.

Burdock Root (Arctium lappa)

Antioxidant Status Improvement

The only tested dose is 6 g of root per day brewed as tea for 42 days; capsules at 500-1500 mg/day and tinctures are common on labels but untested and not interchangeable with tea.

Clovinol® (Clove Bud Extract for Metabolic — Akay Bioactives)

6-fold plasma glutathione increase vs synthetic GSH

Per Akay Clovinol product specification

CompleteGreens™ (Comprehensive Greens Base)

MitoPrime ergothioneine antioxidant power

3–8g/day comprehensive greens blend; specific CompleteGreens™ dosing per NNB product

CyaniMax® (Cyanidin 3-Glucoside — BGG)

C3G anthocyanin with laboratory antioxidant activity

Per BGG CyaniMax product specification

Leucoselect® Phytosome (Grape Seed Phytosome — Indena)

Antioxidant Activity

100-300 mg/day Leucoselect Phytosome (research-validated)

MitoQ (Mitoquinone)

Reduced mitochondrial oxidative stress (mechanism)

ROSSMAN 2018 VASCULAR: 20 mg/day × 6 wk endothelial function. PD PHASE II: 40-80 mg/d

Antioxidant support, with mixed human results

2–7 g/day leaf powder; clinical studies typically use 6–8 g/day

Nutroxsun® (Rosemary + Grapefruit Skin Protection)

Lower oxidative damage marker (DNA damage was not measured)

100 to 250 mg/day taken daily; the single trial tested both doses and found no difference between them.

Quercefit® (Quercetin Phytosome — Indena)

Antioxidant and Anti-Inflammatory Action

250 to 500 mg/day, about 100 to 200 mg quercetin, in the studies; the 1,000 mg/day senolytic figure comes from trials pairing quercetin with a prescription drug, not tested for this product.

Silbinol® (Indian Kino Pterostilbene Extract — Sabinsa)

Antioxidant activity (laboratory studies)

50 mg/day Silbinol® Pterocarpus marsupium extract

AstaSana™ (Natural Astaxanthin)

Antioxidant activity

Commonly 4 to 12 mg of astaxanthin per day.

Betalains (Beetroot Pigments)

Antioxidant activity, mostly measured in the test tube

BEETROOT JUICE: 250-500 mL/day (~5-10 mmol nitrate + 30-100 mg betalains). FREEZE-DRI

Broccoli Extract (Glucoraphanin)

Antioxidant pathway activation — what's actually happening

Glucoraphanin: 30-100 mg/day with myrosinase. Sulforaphane: 10-50 mg/day. ASD trials:

Cosmythic® (Maritime Pine Bark for Skin — Purextract)

Antioxidant defense

Commonly around 50 to 100 mg per day.

Curcumin C3 Reduct® (Tetrahydrocurcuminoids — Sabinsa)

Antioxidant defense

Commonly around 150 to 600 mg per day.

elaVida® (Olive Hydroxytyrosol — DSM)

Antioxidant defense

About 5 mg of hydroxytyrosol per day (the level in 20 g of extra virgin olive oil).

Enzogenol® (Pinus radiata Bark Extract)

Oxidative stress markers in chronic smokers

Cognitive: 480 mg/day × 5 weeks. Mild TBI: 1,000 mg/day × 6-12 weeks. Take with food.

Antioxidant activity in vivo

Hyperlipidemia: 1,000 mg/day × 6 weeks (the best-studied protocol). Asian clinical do

Glabridin (Licorice Isoflavone)

LDL oxidation reduction (6-month trial)

Licorice-root extract with ~60 mg/day glabridin (LDL oxidation); licorice flavonoid oil 300–900 mg/day (body fat). No established pure-glabridin human dose.

HTEssence® (Hydroxytyrosol — Wacker)

Antioxidant defense

Commonly 5 to 25 mg of hydroxytyrosol per day.

Natavid® (Whole Grapevine Extract — Natac)

Antioxidant defense

Per the product specification.

Antioxidant via metabolite effects

Human trials used whole strawberries: about 250 to 500 g fresh, or 10 to 50 g of freeze-dried powder per day; there is no established dose for purified pelargonidin itself.

Phyto-C® (whole-food vitamin C and polyphenol immune complex — FutureCeuticals)

Helps protect cells from oxidative stress

150 mg/day of the finished whole-food blend; acerola supplies the natural vitamin C.

Pomella® (Pomegranate Extract — Verdure Sciences)

Antioxidant biomarker enhancement

Standard cardiovascular protocol: 500-1,500 mg/day Pomella® standardized extract. Mos

S7® (plant-based nitric oxide booster — FutureCeuticals)

Antioxidant support against everyday free radicals

25–50 mg once daily (50 mg used in the main RCT and the 230% NO pilot)

Schisandra Chinensis (Five-Flavor Berry)

Antioxidant and Anti-Inflammatory

1,000 mg/day of extract in both muscle-strength trials, within a common commercial range of 500-2,000 mg/day; berry powder 1-6 g/day.

SelenoForce® (Selenium-Enriched Yeast — Sabinsa)

Glutathione peroxidase antioxidant activity

100 to 200 mcg a day of elemental selenium; upper limit 400 mcg a day from all sources including food.

Tart Cherry Extract

Antioxidant capacity

Recovery: two 8 oz servings of tart cherry juice a day, or 30 mL of concentrate twice a day; sleep: 30 mL of concentrate twice a day. No cited study tested a capsule dose in milligrams.

Antioxidant support for skin and scalp

250 mg/day, 4.5–5.5% anthocyanins

Antioxidant support

AllOlive® (Full-Spectrum Olive Extract — Natac)

Antioxidant defense

Commonly around 250 to 500 mg of the extract per day.

Asta-Marine® (Marine Astaxanthin)

Antioxidant power

Commonly 4 to 12 mg of astaxanthin per day.

Baobab Fruit Powder (Adansonia digitata)

Antioxidant Activity

Commonly used at 5 to 15 g/day of baobab fruit powder, but the human studies did not test a daily powder dose; they used 18.5 to 37 g of concentrated aqueous extract or a single 250 mL drink.

Bilberon® (Standardized Bilberry Extract)

Antioxidant activity (laboratory only)

Commonly 160 mg of standardized extract per day.

Brainberry® (Aronia melanocarpa Extract)

Antioxidant + anti-inflammatory CNS effects

: 90 mg or 150 mg AME daily × 24 wk middle-aged adults. CROSSOVER: 160 mg/day older a

BroccoRaphanin® (Broccoli Seed Glucoraphanin)

Antioxidant defense

Commonly providing tens of milligrams of glucoraphanin per day.

C-Fence® (Sustained-Release Vitamin C — Nutriventia)

Antioxidant protection

The only dose tested is a single 500 mg sustained-release tablet in one small pharmacokinetic study; no daily dose of C-Fence has been tested for immune or antioxidant outcomes.

CaroCare® (Natural Beta-Carotene — DSM)

Antioxidant defense

Commonly providing a few milligrams of beta-carotene per day.

Carotex® (Natural Beta-Carotene and Carotenoids — Zeus Hygia)

Vitamin A and antioxidant support

Typical carotenoid supplements supply a few milligrams per day; the cited trial did not name Carotex or state a dose, so treat this as a general range, not a studied dose.

CocoaGanic® (Organic Cocoa Flavanols)

Antioxidant activity: not measured here

Products commonly provide a few hundred milligrams of cocoa flavanols per day; Cochrane review trials used 30 to 1,218 mg per day. No dose has been tested for CocoaGanic specifically.

Cordiart® (Tomato Nutrient Complex)

Antioxidant defense

Providing about 15 to 30 mg of lycopene per day.

Antioxidant protection

2–8 g/day dried root; 250–500 mg standardized extract three times daily

EGCG (Epigallocatechin Gallate)

Antioxidant Activity

200 to 400 mg/day in most studies; EFSA safety limit is 800 mg/day supplemental EGCG, the level linked with rising liver enzymes.

Antioxidant capacity in laboratory assays

The 60-patient influenza trial used liquid extract at 15 mL four times daily; extract strengths differ widely between products, and no preventive dose is established in the cited evidence.

EllagiRush® (Pomegranate Extract — Arjuna)

Antioxidant defense

No established dose for EllagiRush, since no trial has used it; the cited human trial used pomegranate juice, not a measured extract dose.

EnduBerry™ Nu

Antioxidant rationale is a theory here, not a measured result

The cited trial used 6 g a day of freeze-dried haskap berry powder (about 150 mg anthocyanins), but that was a different company's powder, so no dose has been established for EnduBerry Nu itself.

Ergothioneine (ErgoActive®)

Exceptional cellular antioxidant protection

5–30 mg/day; most human studies use 5–20 mg/day; dietary intake from mushrooms typica

EVNol® (Palm Tocotrienol and Tocopherol Complex, ExcelVite)

Oxidative-damage markers in blood

The trials used 200 mg of mixed tocotrienols twice a day, 400 mg/day total, for 1 to 2 years, delivered as a self-emulsifying softgel rather than plain tocotrienol oil.

Nrf2-pathway antioxidant / pollution-detox support

350 mg/day for 56 days

Luravida® (Cranberry Omega-3 Oil — AHD International)

Antioxidant Activity

Per AHD Luravida product specification (typical 1-3 g/day)

Masquelier's® French Pine Bark (OPCs)

Antioxidant defense

Commonly 100 to 200 mg per day.

Masquelier's® Original OPCs

Antioxidant defense

Commonly 100 to 200 mg per day.

Melostacio® (Mango Leaf Extract)

Anti-inflammatory and antioxidant protection

150 mg/day of mangiferin for 12 weeks in the only human trial, generic and not Melostacio; no published trial has tested Melostacio itself.

MintyBright™ Nu

Antioxidant defense support

150 mg/day for 12 weeks

Morosil® (Moro Red Orange Extract)

Anthocyanin antioxidant content

PIVOTAL DOSE: 400 mg/day Morosil® dry extract. CARDILE 2015: × 12 wk. BRISKEY 2022: ×

MSM (Methylsulfonylmethane)

Sulfur and glutathione (mechanism only)

Standard dose: 1.5-3 g/day, often split as 1 g twice daily. Joint applications: 3-6 g

MyrtiPRO® (BGG Bilberry Extract, Vaccinium myrtillus)

Antioxidant Activity in the Lab, Not Shown in People

43.2 mg of bilberry anthocyanins a day (about 120 mg of extract) in the one trial; BGG's own 160 to 320 mg/day is a supplier recommendation, not a tested dose.

Antioxidant Activity

150-500 mg/day; emerging supplement category; standardized doses not yet well-establi

NeuGrape® (Grape Seed Extract, 95% OPCs)

Lower oxidation markers in blood

No dose of NeuGrape has been tested in a published study; the one cited study used 100 mg/day of ActiVin, a different company's grape seed extract.

Oli-Ola® (Olive Fruit Extract)

Antioxidant defense

250 to 1000 mg of olive extract per day; the authorised antioxidant claim keys to 5 mg of hydroxytyrosol per day, so check the label for standardized hydroxytyrosol.

Olivactive® (Olive Leaf Extract for Immune Support)

Antioxidant phenolic content

No dose of the branded Olivactive extract has been tested in a published trial. Related trials used 100 mg of oleuropein a day, or about 500 mg a day of olive leaf extract.

PhytoPin® (French Maritime Pine Bark Extract)

Antioxidant defense

Commonly 100 to 200 mg per day.

Anti-Inflammatory / Antioxidant

50-250 mg/day; trial used 125 mg twice daily (250 mg/day total)

Reishi Mushroom

Antioxidant protection

1.5–9 g/day whole mushroom powder; 1–1.5 g/day standardized extract

Resvinol® (Trans-Resveratrol)

Antioxidant defense

Commonly 150 to 500 mg of trans-resveratrol per day.

SelectSIEVE® Apple PCQ (Apple Polyphenols)

Antioxidant defense

Around 300 mg of apple polyphenols per day in studies.

SelectSIEVE® Olive (Olive Polyphenols — Bionap)

Antioxidant defense

Commonly 250 to 1000 mg of olive extract per day.

SOD B Dimpless® (Melon Superoxide Dismutase)

Antioxidant defense

Around 10 mg (about 140 IU of SOD) per day.

Antioxidant/singlet oxygen quenching (mechanistic)

CV: 860 mg/day × 20 wk hypercholesterolemia. STRANDBERG 1990: 900 mg/day. PK: 500 mg

Tocotrienols (Vitamin E Family)

Antioxidant Activity (Distinct from Tocopherols)

100-400 mg/day total tocotrienols; for cholesterol/CV: 200-300 mg gamma+delta tocotri

VitaBlue® (concentrated American blueberry extract — FutureCeuticals)

Antioxidant defense

Supplier suggests about 250 to 500 mg/day; no human trial has tested VitaBlue, so there is no established effective dose.

VitaCurrant® (blackcurrant anthocyanin extract — FutureCeuticals)

Antioxidant activity shown in the lab

Blackcurrant anthocyanins about 50 mg/day was used in the eye studies (12.5-50 mg as a single dose in the dark-adaptation study); there is no published dosing study on VitaCurrant itself.

Vitaflavan® (Grape Seed Extract)

Antioxidant defense

Commonly 100 to 300 mg per day.

VitAlign® (plant polyphenol cellular-vitality blend — FutureCeuticals)

Broad-spectrum antioxidant support

Single 50 mg oral dose; 50 mg/day (90-day metabolic study is manufacturer data)

α-Lacys Reset® (Alpha-Lipoic Acid and Cysteine Complex — Nutraceutics)

Antioxidant and redox support

Used at about 25 mg per day in finished formulas, far below the 300 to 1800 mg per day alpha-lipoic acid doses in the weight-loss trials. No trial shows 25 mg reproduces those results.

PhytoServ® (concentrated fruit & vegetable phytonutrient extract — FutureCeuticals)

Supplies natural plant antioxidants

Not established for the finished ingredient; dosed to a "1 serving" phytonutrient equivalent per label

CyanthOx™ (Sea Buckthorn Proanthocyanidin Extract)

Antioxidant capacity (ORAC and cellular)

500 mg CyanthOx 30 (~150 mg proanthocyanidins); commercial products 100-500 mg/day. The 500 mg came from a single acute dose; no daily-dosing trial of this extract has been published.

TruServ® (whole-food fruit & vegetable servings — FutureCeuticals)

Supplies antioxidant phytonutrients

No dose has been studied in humans. TruServ is sold by serving-equivalence, an accounting of how much produce went into the powder, not a tested dose.

Aronia / Chokeberry (Aronia melanocarpa)

Antioxidant Capacity

STANDARDIZED EXTRACT: 100-300 mg/day (25-50 mg anthocyanins) OR juice 200-300 mL/day

Antioxidant and free-radical scavenging

UCHIDA 2011 BIOAVAILABILITY: 50 mg vit C from acerola juice. COMMERCIAL: 100-500 mg p

Curcumin C3 Complex® (Most Studied Curcumin Extract)

Antioxidant markers measured in blood

500-1,000 mg/day standardized to 95% curcuminoids; all the cited trials co-administered piperine (for example 1,500 mg curcuminoids with 15 mg piperine), so account for it.

Antioxidant and anti-inflammatory

DIETARY: 1-4 mg/day (walnuts, cranberries, blueberries, red wine, tea). SUPPLEMENT: 1

Terminalia Chebula (Rejuna®)

High antioxidant activity in laboratory assays

500–1,000 mg/day of standardized aqueous fruit extract, given as 250–500 mg twice daily, the range used in the human trials. Traditional whole-fruit powder use is higher, around 3–5 g/day.

ActiVin® (Grape Seed Proanthocyanidin Extract)

Oxidative stress marker in one uncontrolled study

Commonly 50 to 300 mg per day.

Chaga Mushroom (Inonotus obliquus)

Antioxidant Activity

500 to 2,000 mg/day of extract, or 3 to 4 g of dried chaga per cup of tea. That much dried chaga is high in oxalate, so avoid it if you have kidney disease or kidney stones.

FitGrape® (Grape Polyphenol Extract)

Antioxidant defense

Product labels commonly suggest 100 to 300 mg per day; no published trial has tested FitGrape at any dose.

LingonMax® (Lingonberry Extract — BGG)

Test tube antioxidant score, and what it does not mean

Per BGG LingonMax product specification

MitoGreens® (Mitochondrial Greens Complex)

Antioxidant content and what ORAC means

MitoGreens has not been tested at any dose in a published human trial; the supplier serving is 100 mg of the blend per day.

Noni (Morinda citrifolia)

Antioxidant activity

30–750 mL/day noni juice; most studies use 29–118 mL (1–4 oz) daily; freeze-dried pow

Opextan® (Olive Fruit Extract — Indena)

Verbascoside, the standardised active (laboratory antioxidant work only)

The supplier reports 300 mg/day for skin, but that dose comes from a registry study not cited here; self-affirmed GRAS up to 1,062 mg/day.

SelectSIEVE® Rainbow (Black Rice & Citrus Polyphenol Complex — Roelmi HPC)

Antioxidant defense

VinCare® (Whole Grape Extract — Ethical Naturals)

Antioxidant defense

About 350 mg per day, from the manufacturer's own materials; the only cited trial used a different product, a grape seed extract, so this dose of VinCare has not been tested here.

Eriocitrin / Eriomin® (Lemon Flavonoid)

Antioxidant and anti-inflammatory activity

200–400 mg/day Eriomin® standardized extract; blood sugar: 200 mg/day; uric acid: 200

Antrodia cinnamomea (Niu-Chang-Chih / Stout Camphor Fungus)

Oxidative-stress signaling (animal model)

NASH RCT: 3 capsules/day = 420 mg ACM × 6 months (n=28). SUBHEALTH ALT RCT: 250 mg AC

Ecklonia Cava (Brown Seaweed Polyphenol)

Antioxidant phlorotannins — laboratory assays plus one human trial

Trial doses range from 72 to 1,500 mg/day; the European Food Safety Authority set a maximum safe intake of 263 mg/day for adults, below several research doses.

Antioxidant activity (preclinical)

Traditional/clinical doses: 100-500 mg/day humic acid extract. No FDA-recognized stan

AcaiVida® (Açaí Berry Extract)

Antioxidant defense

Commonly around 1 to 2 g of açaí preparation per day.

Anti-Inflammatory / Antioxidant

No human trial has established a dose for apigenin; supplements are commonly sold at 50-100 mg per day, a range from internet longevity protocols, not clinical testing.

ApPhenols (Apple Polyphenols)

Antioxidant activity: shown in test tubes, not in people

300 mg/day and 600 mg/day for 12 weeks were used in the single human trial, which tested a different company's apple polyphenol. No dose of this branded extract has been tested here.

AppleActiv® (Dried Apple Peel Polyphenols — Leahy Orchards)

Antioxidant support

No cited study established a dose for AppleActiv. A few hundred milligrams of apple peel polyphenols per day is a typical label amount, not researched; the two cited trials fed whole apples.

Astrion® (NuLiv Science Beauty-From-Within)

Skin antioxidant protection

Per Astrion® product specifications; NuLiv Science beauty-from-within dosing data

AuroraBlue® (Wild Alaskan Blueberry Complex)

Antioxidant support

Commonly a few hundred milligrams of the berry complex per day, a label serving rather than a studied dose; no published human study has tested AuroraBlue at any dose.

AuroraGreen® (Wild Alaska Dandelion — Denali BioTechnologies)

Antioxidant activity in laboratory work

Per the product specification.

Bakuchi (Bakuchiol)

Antioxidant and anti-inflammatory mechanisms

The only tested dose was a 0.5% bakuchiol cream applied to the face twice a day for 12 weeks. No oral dose has been tested here, and oral raw seed is not advisable.

Berkemyol® (Olive Leaf Extract — Berkem)

Antioxidant marker: measured and unchanged

The one cited trial used 500 mg/day of a generic olive leaf extract for 8 weeks with no effect; no trial of Berkemyol itself is cited.

BerryPlus™ (Mixed Berry Antioxidant Blend — AuNutra)

Antioxidant support

No fixed clinical dose exists; BerryPlus is a customizable blend with no set composition. The one class-level maqui berry anthocyanin RCT used 162 mg anthocyanins per day for 4 weeks.

ChloroBlast® (Alfalfa Chloroplast Concentrate — Ingredients by Nature)

Antioxidant content

Per the product specification.

Chrysin (5,7-Dihydroxyflavone)

Anti-inflammatory and antioxidant (mechanistic)

400 mg as a single oral dose in the pharmacokinetic study; labels commonly say 500 to 3000 mg/day, a range no trial has tested.

OxiCyan® (Bilberry and Spirulina Antioxidant Complex — Biosfered)

Antioxidant defense

Commonly a few hundred milligrams per day.

PhytoCellTec™ Md Nu

Apple polyphenol antioxidant background

Low daily serving

R-Lipoic Acid (Natural / Stabilized R-ALA)

Antioxidant Activity (Both Water and Lipid Soluble)

Products typically supply 100-300 mg/day of R-ALA. The cited studies gave only single absorption doses (600 mg sodium R-lipoate; 50 to 600 mg racemic thioctic acid), not a daily regimen.

Tremella fuciformis (Snow Mushroom / Silver Ear Fungus)

Antioxidant activity in isolated cells (laboratory work)

No dose has been established in human trials; labels commonly suggest 1 to 3 g of dried fruiting body or 500 to 1,000 mg of extract daily.

TruFulvic® (Fulvic Acid from Shilajit — Natreon)

Antioxidant support

Products commonly supply about 250 to 500 mg per day, but no trial of TruFulvic has established a dose; the cited human study used 250 mg twice daily of purified whole shilajit, a different material.

ZinjaBurn® (Dehydrozingerone)

Free radical scavenging in test tubes and in irradiated mice

No human dose has been studied; the supplier suggests 400 to 600 mg twice daily. The only animal regimen, 100 mg/kg/day in mice, scales to roughly 570 mg/day, below the label's 800 to 1200 mg/day.

AstaZine® (Natural Astaxanthin from Haematococcus pluvialis — BGG)

Visual Function for Digital Screen Users (VDT)

4-12 mg/day AstaZine (research-validated; some applications 12-24 mg)

AMD progression — supportive evidence in intermediate AMD (AREDS2)

6–20 mg/day; AREDS2: 10 mg/day lutein + 2 mg zeaxanthin; eye health: 10–20 mg/day wit

Amla / Indian Gooseberry (Capros®)

Naturally high in vitamin C and polyphenols, with lower CRP in trials

The hyperlipidemia trial used 500 mg/day for 42 days; the diabetes trial used 250 mg or 500 mg of Capros twice a day for 12 weeks. There is no established dose for healthy consumers.

Eye health and visual function

4 to 12 mg/day of astaxanthin from Haematococcus pluvialis; take with a fat-containing meal.

Blood pressure reduction

Standard cardiometabolic dose: 500-2,000 mg/day cold-pressed black seed oil. Higher-d

GOPO® Rosehip (Hyben Vital — Rosa canina)

Hip and knee osteoarthritis pain relief

5 g/day rosehip powder (typically split as 2.5 g twice daily). Onset of pain relief:

Kyolic® (Aged Garlic Extract — Wakunaga)

Blood pressure reduction (extensive trial evidence)

Standard cardiovascular protocol: 1,200-2,400 mg/day Kyolic® in divided doses. Differ

Lutemax® 2020 (Lutein + Both Zeaxanthins — OmniActive)

Three Macular Carotenoids in Dietary Ratio

20 mg lutein + 4 mg total zeaxanthins daily (Lutemax 2020 standard dose)

Niagen® (Nicotinamide Riboside — ChromaDex)

Foundational blood NAD+ elevation evidence

Clinical trial doses: 250-1,000 mg/day Niagen®. Most studies use 300-600 mg/day. Take

Punicalagins (Pomegranate Polyphenols)

Modest blood pressure reduction

POMEGRANATE JUICE: 240 mL/day = ~318 mg punicalagins. POMx: 1000 mg/day. STANDARDIZED

Pycnogenol® (French Maritime Pine Bark)

Blood pressure — modest effect, mostly in hypertensives

50–200 mg/day; cardiovascular: 100–200 mg/day; cognitive: 100 mg/day; athletic perfor

Rosehip (Rosa canina)

Modest pain reduction in osteoarthritis trials (meta-analysis)

STANDARD: 5 g/day rosehip powder (Hyben Vital® / LitoZin®) split 2-3 doses with meals

Selenium Yeast (High-Selenium Yeast)

What the Cancer Trials Actually Found

100-200 µg of elemental selenium a day is the range used in research; the adult tolerable upper limit is 400 µg a day, and 300 µg a day for five years was linked to increased mortality.

Selenomethionine

Hashimoto's Thyroiditis Adjunct

100-200 µg elemental selenium/day; Hashimoto's trials typically 200 µg/day

Lipid profile improvement

1–8 g/day; most clinical trials use 2–4 g/day

Truebroc® (Glucoraphanin Broccoli Seed Extract — Brassica Protection Products)

What the cited human studies actually measured

30-150 mg/day (providing 4-20 mg glucoraphanin) is the usual supplement range; the cited studies used other broccoli sprout preparations, so their doses do not map onto these numbers.

Childhood Mortality Reduction in Vitamin A-Deficient Populations (Not a Benefit for…

RDA 700 mcg RAE/day for women, 900 mcg RAE/day for men; Tolerable Upper Intake Level 3,000 mcg/day of preformed vitamin A (retinol and retinyl esters).

Witholytin® (Olive Leaf Extract — Verdure Sciences)

Reduced fatigue and low energy

Clinical trial protocol: 500 mg twice daily (1,000 mg/day total) for 8 weeks. Mainten

Amlaac® (Amla / Indian Gooseberry Extract)

Healthy cholesterol

Commonly around 500 mg to 1 g per day of amla extract. The pooled meta-analysis used various doses and preparations, and no Amlaac®-specific dose has been established in a trial.

Anserine (β-alanyl-3-methyl-L-histidine)

Verbal memory preservation in older adults

1.0 g/day of an anserine plus carnosine combination (about 750 mg anserine, 250 mg carnosine); no established dose for anserine alone.

ApplePhenon® (Apple Polyphenol Extract — BGG)

Visceral fat: a subgroup finding in a 94 person beverage study

600 mg/day in the 12 week metabolic studies; the brand-named trial used 1200 mg/day; one study included an 1800 mg/day arm to check excessive intake.

BioPerine® (Black Pepper Extract — Sabinsa)

The curcumin figure: widely quoted, not cited here

5-20 mg alongside another compound; the one positive trial used 5 mg with 120 mg CoQ10 for 21 days, while 20 mg with 250 mg resveratrol showed no change in resveratrol levels.

Chlorophyll / Chlorophyllin

Reduction of aflatoxin-DNA adducts (high-risk populations)

AFLATOXIN PROTECTION: 100 mg sodium copper chlorophyllin 3×/day (300 mg/day total). D

Cognigrape® (Vitis vinifera Grape Extract)

Cognitive function in older adults

PIVOTAL: 250 mg/day Cognigrape® × 12 wk single daily dose. 2024 FOLLOW-UP: 250 mg/day

DeltaGold® (Annatto Tocotrienols — American River Nutrition)

Cardiovascular Health

430 or 860 mg/day annatto extract (roughly 300 or 600 mg/day tocotrienol) in the 12-week bone marker trial; the quoted 250 mg/day figure comes from a diabetes trial not cited here.

Greenselect® Phytosome (Decaffeinated Green Tea Catechin Phytosome — Indena)

Weight loss alongside a hypocaloric diet (Di Pierro 2009, blinding not stated)

300 mg/day Greenselect Phytosome, split as 150 mg twice daily (one dose before lunch,

Idebenone (Raxone)

Vision was measured only in a rare inherited eye disease

Prescription doses only: 900 mg/day (300 mg three times daily) for optic neuropathy; 450 to 2,250 mg/day in ataxia trials; in healthy adults given only in pilot studies.

Japanese Knotweed (Polygonum cuspidatum)

Anti-inflammatory effects (small basketball player trial)

40 mg trans-resveratrol/day (200 mg of a 20% extract) in the two 6-week trials; 200 or 600 mg/day in the Gulf War Illness study. Commercial 8% extracts at 250-500 mg give 20-40 mg.

Memophenol™ (Grape + Blueberry Polyphenol Extract)

Episodic memory in healthy elderly

Healthy elderly: 600 mg/day Memophenol™ (containing 258 mg flavonoids) × 6 months. MC

Mexidol (Ethylmethylhydroxypyridine Succinate)

Hemispheric ischemic stroke (EPICA RCT)

MIR 2024 STROKE PROTOCOL: 500 mg IV 2×/day × 10 days, then Mexidol FORTE 250 mg PO 3×

Mitopure® (Urolithin A — Amazentis)

The form used in the published urolithin A trials

Standard clinical dose: 500-1,000 mg/day Mitopure®. Most clinical trials use 500-1,00

Oligonol® (Lychee + Green Tea Polyphenol — Amino Up)

Visceral fat reduction (10-week trial)

Visceral fat protocol: 200 mg/day Oligonol® (50 mg twice daily) for 10 weeks. Periphe

Phaeodactylum tricornutum (PT Microalga)

Plant-Based EPA Source (Bioavailable)

STIEFVATTER 2021 BIOAVAILABILITY: 5.3 g/day whole PT biomass × 2 wk (~150-200 mg EPA

PurTea® (Organic Green Tea Caffeine — Applied Food Sciences)

Energy and alertness

Commonly 100 to 200 mg of caffeine per serving.

Restoridyn® (Tart Cherry Extract — Anthocyte)

Faster jump recovery in one small trial of young women

The label dose is 480 mg once or twice daily, but no cited study tested 480 mg of extract; the recovery trial used 30 ml of tart cherry concentrate twice daily.

Rosmarinic Acid

Studied in people with seasonal hay fever

One hay fever trial used a Perilla frutescens extract supplying 50 mg or 200 mg of rosmarinic acid a day for 21 days; doses for cognition or anxiety are not established here.

Sparassis crispa (Cauliflower Mushroom / Hanabiratake)

Highest β-glucan content (>40% dry weight)

β-GLUCAN content: >40% of dry weight (highest among medicinal mushrooms). MOUSE Sarco

TurmiPure Gold® (Bioavailable Turmeric — Naturex)

Higher Curcuminoid Absorption Per Milligram

Per Naturex/Givaudan TurmiPure Gold product specification

Ubiquinol (Reduced CoQ10)

What the Q-SYMBIO Trial Tested (Ubiquinone, Not Ubiquinol)

Products are typically sold at 100-200 mg/day with a fatty meal; the two cited studies used 200 mg/day and 300 mg/day. Higher amounts were used in diagnosed patients under medical supervision.

VeriSperse® (Stabilized Astaxanthin)

Skin Health: Not Supported by Any Study Cited Here

4-12 mg/day of astaxanthin is the common range; no cited study compared VeriSperse with standard astaxanthin, so its absorption advantage is unverified here.

Xanthigen® (Fucoxanthin + Pomegranate Seed Oil)

Weight loss in obese premenopausal women on a reduced-calorie diet

PIVOTAL: 600 mg Xanthigen®/day × 16 weeks (300 mg PSO + 300 mg brown seaweed extract

Yerba Mate (Ilex paraguariensis)

Caffeine Content (No Energy Trial Cited)

3 g a day of yerba mate capsules for 12 weeks in the only cited trial; supplements sold at 500 to 2,000 mg a day are below the amount that was tested.

Agaricus blazei Murill (AbM / Himematsutake / Royal Sun Mushroom)

A registered trial in people receiving chemotherapy for multiple myeloma (no results cited)

No consumer dose established. The 60 mL per day figure comes from one branded liquid extract (AndoSan) given to patients about 7 weeks; those studies are not cited here.

E-TPGS (Water-Soluble Vitamin E)

Vitamin E source

Per the product or formulation; no supplemental dose has been established for healthy people.

EVSpectra® (Red Palm Oil Concentrate — ExcelVite)

Raises blood carotenoid levels

No trial has used EVSpectra, so there is no studied dose for this material; the human studies behind this page used very different amounts and forms.

Glycyrrhizina (Licorice Flavonoids — BGG)

The H. pylori figure is not supported here

No oral dose here is backed by a cited reference; for licorice containing glycyrrhizin, about 10 mg/day of glycyrrhizic acid is a safe intake and 400 mg/day causes adverse effects in most people.

Maplifa® (Red Maple Leaf Skin Extract — Verdure Sciences)

Photoaging clinical trial — NCT04586816

50-100 mg/day Maplifa® standardized red maple leaf skin extract

Phellinus linteus (Meshimakobu / Sanghuang)

Immune markers in a 30-person pilot trial (trend-level results)

The Korean pilot tested 1,000 mg and 2,000 mg a day; the planned trial uses 1,000 mg a day. Human data are one small pilot, so no effective dose is established. Avoid if you have an autoimmune condition.