Home Ingredients Hydrovas® 10 (Olive Hydroxytyrosol Extract)
Antioxidant

Hydrovas® 10 (Olive Hydroxytyrosol Extract)

Olea europaea
Evidence Level
Moderate
2 Clinical Trials
3 Documented Benefits
3/5 Evidence Score

Hydrovas® 10 is a branded water-soluble olive (Olea europaea) fruit extract from Bionap standardized to 10–12% hydroxytyrosol plus tyrosol, marketed for cardiovascular and antioxidant support. Hydroxytyrosol is a well-studied olive polyphenol antioxidant that carries an authorized EFSA health claim: olive-oil polyphenols protect blood lipids from oxidative damage at 5 mg/day of hydroxytyrosol and derivatives. Honest framing: the class evidence is strong; Hydrovas 10's own branded trials are not separately PubMed-indexed.

Studied Dose 50–100 mg/day of the extract; the EFSA claim is met at 5 mg/day of hydroxytyrosol and its derivatives. Take with food.
Active Compound Water-soluble olive (Olea europaea) fruit extract standardized to 10–12% hydroxytyrosol and tyrosol. Hydrovas® 10 is manufactured by Bionap.

Benefits

Protects blood lipids from oxidation (EFSA-authorized claim)

Hydroxytyrosol and related olive polyphenols carry an authorized EFSA health claim for protecting LDL cholesterol from oxidative damage at 5 mg/day — a rare, regulator-backed benefit. Hydrovas 10 delivers this active.

Supported by Trial 2, Trial 1

Blood-lipid protection, not blood-pressure lowering

The authorized benefit for olive polyphenols is protecting blood lipids from oxidation, not lowering blood pressure. In the one placebo-controlled trial of a standardised olive extract in adults with raised blood pressure, systolic pressure and LDL fell about equally in the extract and placebo arms, with no significant advantage for the extract.

Supported by Trial 1

Potent antioxidant / anti-inflammatory action

Hydroxytyrosol is a well-characterised dietary antioxidant with documented anti-inflammatory activity in laboratory studies, supporting general antioxidant intake.

Supported by Trial 2

Mechanism of action

1

LDL oxidation protection

Hydroxytyrosol incorporates into lipoproteins and neutralizes free radicals, protecting LDL cholesterol from the oxidation that drives atherosclerosis — the basis for the EFSA claim.

2

Endothelial and anti-inflammatory effects

Olive polyphenols support nitric-oxide-mediated vascular function and dampen inflammatory signaling, contributing to cardiovascular benefit.

Clinical trials

1
Olive Extract Blood-Pressure RCT (null for blood pressure; different extract)
PubMed

Double-blind, placebo-controlled randomized trial of olive extracts on blood pressure and cardiovascular markers (PLoS One, 2026).

56 adults with elevated systolic blood pressure (a different olive extract, not Hydrovas 10).

In 56 adults with elevated systolic blood pressure, a standardised olive extract (about 25 mg/day hydroxytyrosol) taken for eight weeks did not lower blood pressure more than placebo. Systolic pressure fell about equally in both arms (extract minus 8.3 mmHg, placebo minus 7.3 mmHg, no significant between-group difference), and total cholesterol and LDL also fell similarly in both groups. The extract tested was not Hydrovas 10.

2
Review and EFSA opinion (not a clinical trial): olive polyphenol antioxidant evidence
PubMed

Reviews of olive polyphenols plus the EFSA opinion underpinning the authorized health claim.

Not a study in people: a review and the EFSA opinion.

Olive polyphenols (hydroxytyrosol) show strong antioxidant and anti-inflammatory activity, and the EFSA claim authorizes the LDL-protection benefit at 5 mg/day.

Side effects and drug interactions

Common Potential side effects

Generally very well tolerated; olive polyphenols are part of the Mediterranean diet.
Mild gastrointestinal upset possible.
Allergy to olive is uncommon but possible.
No significant safety concerns at recommended intakes.

Important Drug interactions

Antihypertensives: possible mild additive blood-pressure lowering.
Anticoagulants/antiplatelets: theoretical mild additive effect at high polyphenol intakes.
Generally a very low-interaction, food-derived profile.

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Frequently asked questions about Hydrovas® 10 (Olive Hydroxytyrosol Extract)

What is Hydrovas 10?

Hydrovas 10 is a branded, water-soluble olive fruit extract from Bionap standardized to 10–12% hydroxytyrosol and tyrosol, taken for cardiovascular and antioxidant support. Hydroxytyrosol is a well-studied olive polyphenol antioxidant.

Is the heart benefit actually proven?

Olive polyphenols carry an authorized EFSA health claim for protecting blood lipids from oxidative damage at 5 mg/day of hydroxytyrosol — a regulator-backed benefit. The one placebo-controlled trial of a standardised olive extract on blood pressure was null (both arms fell about equally with no significant difference), so the proven benefit is protection of blood lipids from oxidation rather than blood-pressure lowering. Hydrovas 10's own branded trials are not separately PubMed-indexed, but the class evidence for the lipid-oxidation claim is strong.

What is Hydrovas 10 used for?

Hydrovas 10 is researched primarily for Antioxidant. Hydroxytyrosol and related olive polyphenols carry an authorized EFSA health claim for protecting LDL cholesterol from oxidative damage at 5 mg/day — a rare, regulator-backed benefit. Hydrovas 10 delivers this active.

What is the recommended dosage of Hydrovas 10?

The clinically studied dose is 50–100 mg/day of the extract; the EFSA claim is met at 5 mg/day of hydroxytyrosol and its derivatives. Take with food. Always follow the product label and check with a healthcare provider for personal advice.

Is Hydrovas 10 safe, and does it have side effects?

For most healthy adults, Hydrovas 10 is well tolerated at studied doses. Reported effects can include: Generally very well tolerated; olive polyphenols are part of the Mediterranean diet. Mild gastrointestinal upset possible. It may also interact with some medications. Hydrovas 10 is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Hydrovas 10 interact with any medications?

Possible interactions include: Antihypertensives: possible mild additive blood-pressure lowering. Anticoagulants/antiplatelets: theoretical mild additive effect at high polyphenol intakes. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Hydrovas 10?

NutraSmarts rates the evidence for Hydrovas 10 as Moderate (3 out of 5). It is backed by 2 clinical trials and 2 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(2 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Lauwers S, Breynaert A, Verlaet A, Fransen E, Bringmans T, Roth L, et al. Evaluation of the effect of olive extracts on blood pressure and cardiovascular health markers in adults: Findings from a double-blind, placebo-controlled, randomised trial. PLoS One. 2026;21(3):e0344278. doi: 10.1371/journal.pone.0344278.PubMedUsed to support: In 56 adults with systolic blood pressure of at least 130 mmHg, a standardised olive extract (about 25 mg/day hydroxytyrosol; the study was part-funded by Tilman sa) taken daily for eight weeks did not lower blood pressure or LDL more than placebo. Systolic pressure fell about equally in both arms (extract minus 8.3 mmHg, placebo minus 7.3 mmHg) with no significant between-group difference, and total cholesterol and LDL changes also did not differ. The extract tested was not Hydrovas 10.
  2. Bucciantini M, Leri M, Nardiello P, Casamenti F, Stefani M Olive Polyphenols: Antioxidant and Anti-Inflammatory Properties. Antioxidants (Basel). 2021;10(7). doi: 10.3390/antiox10071044.PubMedUsed to support: A review of olive polyphenols' antioxidant and anti-inflammatory properties; hydroxytyrosol (the Hydrovas 10 active) also carries an authorized EFSA claim for protecting blood lipids from oxidative damage at 5 mg/day.