Home Ingredients Resvinol® (Trans-Resveratrol)
LongevityCardiovascularAntioxidant

Resvinol® (Trans-Resveratrol)

Evidence Level
Limited
1 Clinical Trial
3 Documented Benefits
2/5 Evidence Score

Resvinol® supplies trans-resveratrol, the polyphenol found in red grapes and Japanese knotweed that became famous as a longevity and heart-health compound. Resveratrol is studied for supporting cardiometabolic health and activating cellular maintenance pathways.

Studied Dose Commonly 150 to 500 mg of trans-resveratrol per day.
Active Compound Trans-resveratrol, a stilbene polyphenol from Japanese knotweed and grapes.

Benefits

Cardiometabolic support

A meta-analysis found resveratrol supported improvements in some cardiometabolic risk factors, the basis for its heart-health positioning.

Supported by Trial 1

Antioxidant defense

Resveratrol is a polyphenol antioxidant that helps protect cells and blood vessels from oxidative stress.

Supported by Trial 1

Cellular longevity interest

Resveratrol is studied for activating sirtuin pathways involved in cellular maintenance and healthy aging.

Supported by Trial 1

Mechanism of action

1

Sirtuin activation

Resveratrol is studied for activating SIRT1, a protein linked to cellular stress resistance and metabolic health.

2

Antioxidant and vascular action

Resveratrol scavenges free radicals and supports healthy blood-vessel function.

Clinical trials

1
Resveratrol and Cardiometabolic Risk — Meta-Analysis
PubMed

Meta-analysis of randomized trials of resveratrol on cardiometabolic risk factors. (Sergi et al. 2020, Archives of Medical Science - Atherosclerotic Diseases)

Adults with and without metabolic syndrome.

Resveratrol supported improvements in several cardiometabolic risk factors versus control.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
High doses can cause digestive upset.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Anticoagulants — resveratrol may have a mild additive effect; monitor.
Drugs metabolized by the liver — possible interaction at high doses; consult a doctor.
Tell your doctor if pregnant or breastfeeding.

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Frequently asked questions about Resvinol® (Trans-Resveratrol)

What is Resvinol?

Resvinol® supplies trans-resveratrol, the polyphenol found in red grapes and Japanese knotweed that became famous as a longevity and heart-health compound. Resveratrol is studied for supporting cardiometabolic health and activating cellular maintenance pathways.

What is Resvinol used for?

Resvinol is researched primarily for Longevity, Cardiovascular, and Antioxidant. A meta-analysis found resveratrol supported improvements in some cardiometabolic risk factors, the basis for its heart-health positioning.

What is the recommended dosage of Resvinol?

The clinically studied dose is Commonly 150 to 500 mg of trans-resveratrol per day. Always follow the product label and check with a healthcare provider for personal advice.

Is Resvinol safe, and does it have side effects?

For most healthy adults, Resvinol is well tolerated at studied doses. Reported effects can include: Generally well-tolerated. High doses can cause digestive upset. It may also interact with some medications. Resvinol is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Resvinol interact with any medications?

Possible interactions include: Anticoagulants — resveratrol may have a mild additive effect; monitor. Drugs metabolized by the liver — possible interaction at high doses; consult a doctor. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Resvinol?

NutraSmarts rates the evidence for Resvinol as Limited (2 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Sergi C, Chiu B, Feulefack J, et al. Usefulness of resveratrol supplementation in decreasing cardiometabolic risk factors comparing subjects with metabolic syndrome and healthy subjects with or without obesity: meta-analysis using multinational, randomised, controlled trials. Arch Med Sci Atheroscler Dis. 2020;5:e98-e111..PubMedUsed to support: Meta-analysis supporting cardiometabolic benefit of resveratrol.