Oli-Ola® (Olive Fruit Extract)

Olea europaea
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

Oli-Ola® is an olive (Olea europaea) fruit extract rich in hydroxytyrosol, the olive's most powerful antioxidant. It is studied for antioxidant and cardiovascular support, and is also used for skin health.

Studied Dose Commonly 250 to 1000 mg of olive extract per day.
Active Compound Olive (Olea europaea) polyphenols, oleuropein and hydroxytyrosol.

Benefits

Cardiovascular support

Olive polyphenols such as oleuropein and hydroxytyrosol are studied for supporting healthy blood pressure and blood-vessel function.

Antioxidant defense

Hydroxytyrosol and oleuropein are powerful antioxidants that protect cells and LDL cholesterol from oxidation.

Metabolic support

Olive polyphenols are studied for supporting healthy blood-sugar and lipid markers.

Mechanism of action

1

Olive polyphenol action

Oleuropein and hydroxytyrosol support nitric-oxide-mediated blood-vessel relaxation and antioxidant defense.

2

Anti-inflammatory action

Olive polyphenols calm oxidative and inflammatory stress in blood vessels and tissues.

Clinical trials

1
Olive Polyphenols and Cardiovascular Markers — RCT
PubMed

Randomized placebo-controlled clinical trial of olive leaf extract on cardiovascular health markers. (Stevens et al. 2021, European Journal of Nutrition)

Adults.

Olive polyphenol extract supported improvements in cardiovascular health markers versus placebo.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Mild digestive upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Blood pressure medication — olive polyphenols may have an additive effect; monitor.
Diabetes medication — may modestly lower blood sugar; monitor.
Tell your doctor if you take cardiovascular medication.

Frequently asked questions about Oli-Ola® (Olive Fruit Extract)

What is Oli-Ola?

Oli-Ola® is an olive (Olea europaea) fruit extract rich in hydroxytyrosol, the olive's most powerful antioxidant. It is studied for antioxidant and cardiovascular support, and is also used for skin health.

What is Oli-Ola used for?

Oli-Ola is researched primarily for Cardiovascular and Antioxidant. Olive polyphenols such as oleuropein and hydroxytyrosol are studied for supporting healthy blood pressure and blood-vessel function.

What is the recommended dosage of Oli-Ola?

The clinically studied dose is Commonly 250 to 1000 mg of olive extract per day. Always follow the product label and check with a healthcare provider for personal advice.

Is Oli-Ola safe, and does it have side effects?

For most healthy adults, Oli-Ola is well tolerated at studied doses. Reported effects can include: Generally well-tolerated. Mild digestive upset is occasionally reported. It may also interact with some medications. Oli-Ola is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Oli-Ola interact with any medications?

Possible interactions include: Blood pressure medication — olive polyphenols may have an additive effect; monitor. Diabetes medication — may modestly lower blood sugar; monitor. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Oli-Ola?

NutraSmarts rates the evidence for Oli-Ola as Moderate (3 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Stevens Y, Winkens B, Jonkers D, et al. The effect of olive leaf extract on cardiovascular health markers: a randomized placebo-controlled clinical trial. Eur J Nutr. 2021;60(4):2111-2120..PubMedUsed to support: RCT supporting cardiovascular benefit of olive polyphenols (the active in this branded olive extract).