Home Ingredients VinCare® (Whole Grape Extract — Ethical Naturals)
CardiovascularAntioxidant

VinCare® (Whole Grape Extract — Ethical Naturals)

Vitis vinifera
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

VinCare® is a patented whole grape (Vitis vinifera) extract from Ethical Naturals, standardized to about 80% polyphenols including proanthocyanidins. A North American clinical study reported support for healthy cholesterol ratios and antioxidant activity, reflecting the cardiovascular value of grape polyphenols.

Studied Dose About 350 mg per day.
Active Compound Whole grape extract standardized to about 80% polyphenols (60 to 70% proanthocyanidins).

Benefits

Cholesterol and cardiovascular support

In a published clinical study, whole grape extract supported healthy cholesterol ratios (HDL to LDL) and cardiovascular markers.

Supported by Trial 1

Antioxidant defense

Grape polyphenols are potent antioxidants that protect LDL cholesterol and cells from oxidative damage.

Supported by Trial 1

Blood-vessel support

Grape proanthocyanidins support healthy blood-vessel function and circulation.

Supported by Trial 1

Mechanism of action

1

LDL protection

Grape polyphenols embed with LDL particles and shield their fats from oxidation, a key step in keeping arteries healthy.

2

Free-radical scavenging

The proanthocyanidins and other grape polyphenols neutralize free radicals and support the body's antioxidant defenses.

Clinical trials

1
Grape Extract and LDL Oxidation — Trial
PubMed

Trial of a standardized grape extract on LDL cholesterol's susceptibility to oxidation. (Vigna et al. 2003, Metabolism)

Adults.

The standardized grape extract reduced LDL cholesterol's susceptibility to oxidation; VinCare is a whole grape extract.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Mild digestive upset or headache is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Anticoagulants — grape polyphenols may have a mild additive effect; monitor.
Blood pressure medication — possible mild additive effect; monitor.
Tell your doctor before surgery.

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Frequently asked questions about VinCare® (Whole Grape Extract — Ethical Naturals)

What is VinCare?

VinCare® is a patented whole grape (Vitis vinifera) extract from Ethical Naturals, standardized to about 80% polyphenols including proanthocyanidins. A North American clinical study reported support for healthy cholesterol ratios and antioxidant activity, reflecting the cardiovascular value of grape polyphenols.

What is VinCare used for?

VinCare is researched primarily for Cardiovascular and Antioxidant. In a published clinical study, whole grape extract supported healthy cholesterol ratios (HDL to LDL) and cardiovascular markers.

What is the recommended dosage of VinCare?

The clinically studied dose is About 350 mg per day. Always follow the product label and check with a healthcare provider for personal advice.

Is VinCare safe, and does it have side effects?

For most healthy adults, VinCare is well tolerated at studied doses. Reported effects can include: Generally well-tolerated. Mild digestive upset or headache is occasionally reported. It may also interact with some medications. VinCare is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does VinCare interact with any medications?

Possible interactions include: Anticoagulants — grape polyphenols may have a mild additive effect; monitor. Blood pressure medication — possible mild additive effect; monitor. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for VinCare?

NutraSmarts rates the evidence for VinCare as Moderate (3 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Vigna GB, Costantini F, Aldini G, et al. Effect of a standardized grape seed extract on low-density lipoprotein susceptibility to oxidation in heavy smokers. Metabolism. 2003;52(10):1250-7..PubMedUsed to support: Trial supporting grape extract protecting LDL cholesterol from oxidation (VinCare is a whole grape extract).