Home Ingredients EllagiRush® (Pomegranate Extract — Arjuna)
AntioxidantCardiovascular

EllagiRush® (Pomegranate Extract — Arjuna)

Punica granatum
Evidence Level
Limited
0 Clinical Trials
3 Documented Benefits
2/5 Evidence Score

EllagiRush® is a standardized pomegranate (Punica granatum) extract from Arjuna Natural, sold as concentrated for water soluble ellagitannins and polyphenols with better absorption, which is a manufacturer claim rather than a tested finding. No published study has tested EllagiRush itself. The research cited on this page is on ordinary pomegranate juice and generic pomegranate supplements, and it mostly measures oxidative stress markers in blood rather than how people actually feel or fare.

Studied Dose There is no established dose for EllagiRush, because no trial has used it. The one year human trial cited here used pomegranate juice rather than a measured extract dose, and the pooled analysis combined many different pomegranate products and amounts.
Active Compound Pomegranate extract standardized for ellagitannins and polyphenols. The minimum 70 percent polyphenol figure is the manufacturer's own specification, not a value confirmed by any of the studies cited here.

Benefits

Antioxidant defense

A 2023 pooled analysis of randomized trials of generic pomegranate supplements found lower blood markers of oxidative stress, including MDA and oxidized LDL, and higher antioxidant enzyme readings. These are laboratory measurements in blood, not evidence of protected cells or blood vessels, and none of the pooled trials used EllagiRush.

Cardiovascular support

The heart related evidence here is thin and indirect. One randomized trial gave pomegranate juice for a year to people on kidney dialysis, a very specific patient group, and reported lower oxidative stress and inflammation markers plus fewer infections. The other source is a 2009 review article summarizing older pomegranate juice studies rather than new data. Nothing cited shows what a pomegranate extract does for blood vessel function or circulation in a healthy person.

Gut and cellular health

Gut bacteria convert pomegranate ellagitannins into compounds called urolithins, which are an active research area. How much you produce depends on your own gut bacteria, and many people convert very little. None of the studies cited on this page measured urolithins or gut health, so this is background science rather than a demonstrated benefit of this product.

Mechanism of action

1

Ellagitannin antioxidants

Pomegranate's ellagitannins and punicalagins neutralize free radicals in laboratory tests, and human trials of generic pomegranate products have shown shifts in blood antioxidant markers. This is a proposed mechanism measured in test tubes and blood samples, not a proven health outcome.

2

Urolithin conversion

Gut bacteria transform pomegranate ellagitannins into urolithins. Urolithin research is still early, output varies a lot from person to person depending on gut bacteria, and none of the references on this page tested urolithins, cellular renewal or metabolic outcomes.

Clinical trials

Side effects and drug interactions

Common Potential side effects

Pomegranate juice and pomegranate extracts were generally well tolerated in the published trials, which reported few side effects. No safety data has been published for EllagiRush specifically.
Mild digestive upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Blood pressure medication — pomegranate may have a mild additive effect; monitor.
Drugs affected by grapefruit-type fruits — consult a doctor.
Tell your doctor if pregnant or breastfeeding.

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Frequently asked questions about EllagiRush® (Pomegranate Extract — Arjuna)

What is EllagiRush?

EllagiRush® is a standardized pomegranate (Punica granatum) extract from Arjuna Natural, sold as concentrated for water soluble ellagitannins and polyphenols with better absorption, which is a manufacturer claim rather than a tested finding. No published study has tested EllagiRush itself.

What is EllagiRush used for?

EllagiRush is researched primarily for Antioxidant and Cardiovascular. A 2023 pooled analysis of randomized trials of generic pomegranate supplements found lower blood markers of oxidative stress, including MDA and oxidized LDL, and higher antioxidant enzyme readings.

What is the recommended dosage of EllagiRush?

The clinically studied dose is There is no established dose for EllagiRush, because no trial has used it. The one year human trial cited here used pomegranate juice rather than a measured extract dose, and the pooled analysis combined many different pomegranate products and amounts. Always follow the product label and check with a healthcare provider for personal advice.

Is EllagiRush safe, and does it have side effects?

For most healthy adults, EllagiRush is well tolerated at studied doses. Reported effects can include: Pomegranate juice and pomegranate extracts were generally well tolerated in the published trials, which reported few side effects. No safety data has been published for EllagiRush specifically. Mild digestive upset is occasionally reported. It may also interact with some medications. EllagiRush is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does EllagiRush interact with any medications?

Possible interactions include: Blood pressure medication — pomegranate may have a mild additive effect; monitor. Drugs affected by grapefruit-type fruits — consult a doctor. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for EllagiRush?

NutraSmarts rates the evidence for EllagiRush as Limited (2 out of 5). It is backed by 3 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(3 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Shema-Didi L, Sela S, Ore L, Shapiro G, Geron R, Moshe G, Kristal B One year of pomegranate juice intake decreases oxidative stress, inflammation, and incidence of infections in hemodialysis patients: a randomized placebo-controlled trial. Free Radical Biology & Medicine. 2012;53(2):297-304. doi:10.1016/j.freeradbiomed.2012.05.013.PubMedUsed to support: Randomized placebo controlled trial in hemodialysis patients, meaning people with end stage kidney disease. One year of pomegranate juice lowered oxidative stress and inflammation markers and reduced infections in that group. The study product was pomegranate juice, not EllagiRush, the trial measured nothing about gut health or urolithins, and findings in dialysis patients do not transfer to healthy people.
  2. Asgary S, Karimi R, Pour PM, Heydarpour F, Mostafaei S, Farzaei MH, Moradi S, Aneva IY Is Consumption of Pomegranate Supplementation Effective on Oxidative Stress Biomarkers Including MDA, ox-LDL, POX 1, GPX, TAC, and TBRAS? Current Problems in Cardiology. 2023;48(8):101198. doi:10.1016/j.cpcardiol.2022.101198.PubMedUsed to support: Systematic review and meta analysis of randomized trials of generic pomegranate supplements. It found reductions in oxidative stress markers (MDA, ox-LDL) and higher antioxidant enzyme readings such as PON1, GPx and TAC. These are blood biomarkers only. The analysis did not measure blood pressure outcomes, heart attacks or any clinical event, and it did not include EllagiRush.
  3. Basu A, Penugonda K Pomegranate juice: a heart-healthy fruit juice. Nutrition Reviews. 2009;67(1):49-56. doi:10.1111/j.1753-4887.2008.00133.x.PubMedUsed to support: A 2009 narrative review titled 'Pomegranate juice: a heart-healthy fruit juice.' A review collects other researchers' studies and generates no new data of its own. Its subject is pomegranate juice, and it predates and does not mention EllagiRush.