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Top Picks — Weight Management

⚖️ Best Weight Management Supplements

Thermogenic, satiety, and metabolic ingredients clinically validated for weight loss, body composition improvement, and appetite control.

108 ingredients reviewed Ranked by clinical evidence

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Top 5 — Ranked by Evidence

Glucomannan (Konjac Root Fiber)

Weight loss and appetite suppression

About 3 g/day (1 g three times daily before meals) in the cholesterol meta-analysis; always take with a large glass of water.

Weight Management Support

250–500 mg/day EGCG standardized extract; whole green tea: 3–5 cups/day (≈240–320 mg

Capsaicin / Capsicum Extract (Cayenne Pepper)

Thermogenic energy expenditure (class evidence)

2-10 mg total capsaicinoids/day (from 25-100 mg capsicum extract) in weight trials; exercise studies used a single 12 mg dose before training.

CLA (Conjugated Linoleic Acid)

Body fat reduction

3.2–6.4 g/day total CLA; most RCTs use 3.2 g/day; body composition effects require 3+

Saffron Extract (Crocus sativus)

Snacking reduction and weight management

Depression (most-studied): 30 mg/day standardized stigma extract × 6-8 weeks. PMS: 15

📈 Fastest Growing Weight Management Ingredients

Branded ingredients seeing rapid growth in formulator adoption and clinical research in 2024–2026.

Capsimax® (Beadlet-Encapsulated Capsicum Extract — OmniActive)

Body fat reduction over 12 weeks

100 mg/day (~2 mg capsaicinoids); some trials use 2x 100 mg (4 mg capsaicinoids).

Greenselect® Phytosome (Decaffeinated Green Tea Catechin Phytosome — Indena)

Weight loss alongside a hypocaloric diet (Di Pierro 2009, blinding not stated)

300 mg/day (150 mg twice daily); some trials 150 mg/day.

Svetol® (Decaffeinated Green Coffee Extract — Givaudan/Naturex)

Weight loss: a small effect from weak studies

400 mg/day before meals, or up to 400 mg three times daily. None of the cited studies tested…

🔬 Future Weight Management Ingredients to Watch

Lower current evidence but active research underway — these may become top picks within 2–3 years.

ApplePhenon® (Apple Polyphenol Extract — BGG)

Visceral fat: a subgroup finding in a 94 person beverage study

600 mg/day in the 12 week metabolic studies; the brand-named trial used 1200 mg/day; one study…

Capsifen® (Bioavailable Capsaicinoids via FenuMat® — Akay Bioactives)

Enhanced fat oxidation

100-200 mg/day.

Glucomannan (Konjac Root Fiber)

Weight: a small and inconsistent effect

About 3 g/day (1 g three times daily before meals) in the cholesterol meta-analysis; always…

CGA-7™ (Green Coffee Chlorogenic Acid Complex)

Modest weight and body-fat support

Manufacturer trial: 250 mg twice daily (500 mg/day) for 12 weeks. Green coffee studies…

Recommended Weight Management Products

Heads up: NutraSmarts may earn a commission from purchases made through these links, at no extra cost to you. We curate these picks based on the same evidence we cite throughout the page. Full disclosure.

Real products featuring the best-evidenced weight management ingredients ranked above — chosen for clinically-studied forms and doses, third-party testing, and value. Match the supplement to your specific need.

Best for appetite control & satiety Amazon →

NOW Foods Glucomannan

Konjac root fiber — 575 mg/cap

Glucomannan (konjac root fiber) is the most evidence-backed soluble fiber for satiety — taken with a full glass of water 30 minutes before meals, it expands in the stomach to reduce calorie intake. Has FDA-approved health claim for promoting feelings of fullness. Effects are mechanical (physical fullness) rather than metabolic, so they work the same day. NOW Foods is the trusted budget brand at this dose range.

Best metabolic modulator Amazon →

Thorne Berberine

Berberine HCl + Phytosome — 1000 mg per serving

Berberine has the strongest single-supplement evidence for weight management — clinical trials show 3-5 lbs lost over 12 weeks via insulin sensitization, AMPK activation, and modest GLP-1 upregulation. Often called "nature's Ozempic" but expect ~2-3% body weight reduction vs. semaglutide's 15-20% — meaningful but not equivalent. Thorne combines Berberine HCl and Berberine Phytosome (enhanced absorption form). NSF Contents Certified for purity verification.

Best for waist and body composition (small trials) Amazon →

Morosil® Red Orange Complex

Morosil® red orange extract — 500 mg

Morosil® is a red orange extract studied at 500 mg/day, with trials in overweight adults reporting reductions in waist circumference, BMI and body fat over about 12 weeks. Those trials are small and manufacturer-linked. It is thought to act on fat-cell metabolism, a different route from berberine.

Best premium option for gut-barrier support Amazon →

Pendulum Akkermansia muciniphila

Live A. muciniphila — 100M AFU delayed-release

Pendulum is currently the only brand selling patented live Akkermansia muciniphila at commercial scale. This gut bacterium is studied for gut-barrier integrity, and its link to the body’s own GLP-1 signalling is mechanistic rather than an outcome measured in weight trials. Premium price, and effects build slowly over 4 to 8 weeks. Not a substitute for prescribed medication.

All Weight Management Ingredients (108)

Glucomannan (Konjac Root Fiber)

Weight loss and appetite suppression

About 3 g/day (1 g three times daily before meals) in the cholesterol meta-analysis; always take with a large glass of water.

Weight Management Support

250–500 mg/day EGCG standardized extract; whole green tea: 3–5 cups/day (≈240–320 mg

Capsaicin / Capsicum Extract (Cayenne Pepper)

Thermogenic energy expenditure (class evidence)

2-10 mg total capsaicinoids/day (from 25-100 mg capsicum extract) in weight trials; exercise studies used a single 12 mg dose before training.

CLA (Conjugated Linoleic Acid)

Body fat reduction

3.2–6.4 g/day total CLA; most RCTs use 3.2 g/day; body composition effects require 3+

Saffron Extract (Crocus sativus)

Snacking reduction and weight management

Depression (most-studied): 30 mg/day standardized stigma extract × 6-8 weeks. PMS: 15

ChitoClear® (Chitosan — Primex)

Weight management

Commonly 1 to 3 grams per day with meals.

Chromax® (Chromium Picolinate)

Body weight: about 1 kg in a meta analysis, and the authors doubted it mattered

200–1,000 mcg/day chromium as Chromax® chromium picolinate; insulin sensitivity: 200–

Fibruline® (Chicory Inulin — Cosucra)

Weight and appetite management

Commonly 5 to 15 grams per day.

Lactobacillus plantarum

BMI and body weight reduction in overweight adults

10–50 billion CFU/day; 299v strain typically 20 billion CFU/day; weight management st

MCT Oil (Medium-Chain Triglycerides)

Weight management and satiety

18 to 24 g/day in the weight-loss trial, up to 30 g/day in others; start near 5 g and build up, since higher doses commonly cause diarrhea.

NEOBEE® (Medium-Chain Triglycerides — Stepan)

Body composition

Commonly 10 to 20 grams per day with meals.

Capsimax® (Beadlet-Encapsulated Capsicum Extract — OmniActive)

Body fat reduction over 12 weeks

100 mg/day Capsimax (providing 2 mg total capsaicinoids) is the standard clinical dos

Capsifen® (Bioavailable Capsaicinoids via FenuMat® — Akay Bioactives)

Enhanced fat oxidation

100-200 mg/day Capsifen (Roopashree 2024 trial protocol). The 200 mg/day dose produce

Mycoprotein (Quorn)

Satiety and weight management

Typical dietary serving: 90-180 g cooked mycoprotein per meal (providing 11-22 g prot

Weight and waist support

~10 billion CFU/day

Super CitriMax® (Calcium HCA — Lonza)

Appetite Control and Satiety

1,500-4,500 mg/day Super CitriMax (providing 900-2,700 mg HCA) divided in doses

Trpti™ (Bioavailable OEA for Metabolic/Gut Health)

Reduced appetite and modest weight reduction (generic OEA trial)

300 mg/day (delivering 250 mg OEA) as two 150 mg capsules; a 150 mg/day dose is also described, but only in an unpublished, unverified manufacturer study.

GarCitrin® (Garcinia + BioPerine — Sabinsa)

Short term weight loss, small in size and uncertain in relevance

500 mg/day (about 500 mg HCA calcium salt plus 25 mg garcinol per dose); the cited trials tested other Garcinia and HCA preparations, not GarCitrin.

Adipromin® (Herbal Weight-Management Complex)

Weight and fat loss

Around 900 mg per day in the clinical study.

Beanblock® (White Kidney Bean Extract — Indena)

Carbohydrate and weight management

Around 500 mg taken shortly before a starch-containing meal.

Weight Management

500 to 1,500 mg per day, split into 2 or 3 doses with meals. Long-term safety at these doses has not been established.

Clarinol® (Conjugated Linoleic Acid — Stepan Lipid Nutrition)

Body fat and composition

3 to 4 grams per day of CLA isomers.

Fibersol® (Digestion-Resistant Maltodextrin — ADM/Matsutani)

Satiety and appetite

Commonly 5 to 10 grams per day.

Metabolaid® (Hibiscus + Lemon Verbena)

AMPK activation and fat oxidation

500 mg/day Metabolaid® (325 mg lemon verbena + 175 mg hibiscus); taken before exercis

Phase 2® (White Kidney Bean Extract — Ashland)

Weight and fat loss

Commonly 500 mg to 1 g before starchy meals.

Chimax® (Chitosan)

Weight management

Commonly 1 to 3 grams per day with meals.

GCBest® (Green Coffee Bean Extract)

Weight management

Commonly 200 to 400 mg of green coffee extract per day.

Hydroxycitric Acid / HCA (Garcinia cambogia)

Proposed appetite suppression via serotonin

1,500–4,667 mg/day Garcinia cambogia extract (providing 900–2,800 mg HCA); most studi

Svetol® (Decaffeinated Green Coffee Extract — Givaudan/Naturex)

Weight loss: a small effect from weak studies

400 mg/day before meals, or up to 400 mg three times daily. None of the cited studies tested this branded extract by name, and two used coffee drinks rather than capsules.

Weight Management

25–35 mcg/day (AI); blood sugar studies used 200–1,000 mcg/day chromium picolinate in people with diagnosed type 2 diabetes rather than healthy adults.

FenuLife® (Fenugreek Galactomannan — BioActor)

Satiety and weight support

Products typically supply a few grams of fenugreek galactomannan fiber per day with meals. No FenuLife-specific dose-finding trial; the pooled doses were whole-seed preparations.

InnoSlim® (Stimulant-Free Fat Burning)

Stimulant-free fat loss and body composition improvement

250 mg/day InnoSlim®; human study confirmed significant fat loss, glucose reduction,

Morosil® (Moro Red Orange Extract)

Modest body weight and fat mass reduction

PIVOTAL DOSE: 400 mg/day Morosil® dry extract. CARDILE 2015: × 12 wk. BRISKEY 2022: ×

Body Weight, Waist, and BMI Reduction

0.14 g FOS/kg/day (roughly 10 g FOS, or 20 to 25 g of syrup for a 70-kg adult) in the single 120-day trial; the higher 0.29 g FOS/kg/day dose caused digestive side effects.

Visceral fat reduction

Published AfperFIT trial: 250 mg twice daily (500 mg/day, standardized to at least 2 percent 6-paradol) for 12 weeks.

Capsinoids (Non-Pungent Capsaicin Analogs)

Increased energy expenditure and fat oxidation

WEIGHT MANAGEMENT (Snitker 2009 + Galgani 2010): 6 mg capsinoids daily × 4-12 wk. ACU

Carolean™ (Carob & Nopal Appetite Control)

Appetite Control / Reduced Food Intake

3 g/day (research-validated dose); typical use as recommended by product

Greenselect® Phytosome (Decaffeinated Green Tea Catechin Phytosome — Indena)

Weight loss alongside a hypocaloric diet (Di Pierro 2009, blinding not stated)

300 mg/day Greenselect Phytosome, split as 150 mg twice daily (one dose before lunch,

Slendesta® (Potato Protein Extract)

Appetite suppression and hunger reduction

600 mg/day Slendesta (providing ~30 mg PI2) before main meals; one trial found no appetite or food-intake effect at that 30 mg PI2 dose.

Appethyl® (Spinach Thylakoid Extract)

Appetite and satiety

Around 5 grams taken before a meal.

CaloriBurn GP® (Grains of Paradise)

Brown adipose tissue activation

Grains of paradise trials used a single 40 mg acute dose (men), 30 mg/day for 4 weeks (women, visceral fat), and 40 mg/day for 5 weeks (low brown-fat adults).

CarbLite® (White Kidney Bean Carb Blocker)

Weight management

Commonly 500 mg to 1 g before starchy meals.

EGCG (Epigallocatechin Gallate)

Weight management, a small effect

200 to 400 mg/day in most studies; EFSA safety limit is 800 mg/day supplemental EGCG, the level linked with rising liver enzymes.

Fabenol® (White Kidney Bean Extract — Indena)

Appetite and energy steadiness

Around 500 mg to 1 g taken before a starchy meal.

Fiit-ns® (Fruit Polyphenol Extract — Fytexia)

Waist and body composition

A standardized daily polyphenol dose.

Finomate® (Green Mate Extract — Frutarom)

Weight management

Per the product specification.

ForsLean® (Coleus forskohlii / Forskolin)

Body-composition changes in one small men's trial (no weight loss)

250 mg/day ForsLean® (providing 25 mg/day forskolin); clinical RCTs at 250 mg twice d

White adipose tissue thermogenesis (UCP1 induction) — animal/preclinical mechanism

2.4-12 mg/day fucoxanthin in human trials, up to 12 mg/day alone for 12 weeks; trials at 1-2 mg/day found no change in body fat.

GBB (Gamma-Butyrobetaine / 'Super Carnitine')

Thermogenic sweating and fat mobilization

10–25 mg/day GBB-EE (ethyl ester) as thermogenic/carnitine elevator; very low dose re

Glavonoid® / Kaneka Glavonoid™ (Licorice Flavonoid Oil)

Body fat and visceral fat 8-week dose-finding RCT

TOMINAGA 2009 DOSE-FINDING: 300, 600, or 900 mg LFO/day × 8 weeks in overweight adult

goBHB® (Beta-Hydroxybutyrate Ketone Salts)

Appetite suppression and satiety

6-12 g of BHB salts per day raises blood ketones by about 0.5 to 1.0 mmol/L, a modest ketosis; as a racemic salt only about half is the usable D-BHB.

ID-alG™ (Ascophyllum Brown Seaweed for Weight Management)

Weight Loss with Body Composition Improvement

400 mg/day (research-validated dose)

KiOnutrime-CsG® (Fungal Chitosan — KitoZyme)

Weight management

Commonly around 2.5 grams per day, taken before meals.

Oligonol® (Lychee + Green Tea Polyphenol — Amino Up)

Visceral fat reduction (10-week trial)

Visceral fat protocol: 200 mg/day Oligonol® (50 mg twice daily) for 10 weeks. Periphe

Reduced body weight and fat, lean mass preserved (branded RCT)

400 mg/day (200 mg twice daily)

SantEnergy™ Nu

Body weight and fat reduction (branded RCT)

400 mg twice daily

Slendacor® (Botanical Blend for Weight Management)

Body Weight and BMI Reduction

900 mg/day (research-validated dose)

Slimaluma® (Caralluma fimbriata for Appetite)

Waist Circumference Reduction

500-1,000 mg/day; clinical trials use 500 mg/day or 1 g/day

SlimPro® (Fish Protein Hydrolysate — Diana)

Appetite control

Around 1.4 grams per day.

StarchLite® (White Kidney Bean Extract)

Weight management

Commonly 500 mg to 1 g before starchy meals.

Stevia (Stevia rebaudiana)

Zero-calorie sugar replacement

Acceptable Daily Intake (steviol equivalents): 4 mg/kg/day (FDA, EFSA). Common per-se

Sukré® (Ultra-Pure Allulose)

Low calorie sweetness and the FDA sugar labeling rule

As sweetener 5-15 g/serving; 5 g and 10 g single doses in the glucose meta-analysis; 7 g twice daily in the body composition trial. The 54 g/day ceiling is not supported by any reference cited here.

ThinOgen® (Fucoxanthin from Brown Seaweed — BGG)

Body Fat Reduction

2.4 mg/day fucoxanthin (research-validated; some products use higher amounts of total

Bitter Orange (Citrus aurantium)

Fat oxidation during exercise (a surrogate marker, not fat loss)

10-50 mg/day synephrine from bitter orange extract (thermogenic studies 20-50 mg/day); do not combine with caffeine, and do not use before or during exercise.

Fabuless® (Structured Lipid Emulsion)

Satiety support (proposed, not confirmed in the cited trial)

Around 5 grams of the emulsion before a meal.

Black Ginger (Kaempferia parviflora / Krachaidum / Thai Ginseng)

Fat oxidation and energy metabolism

Human trials used 25 to 90 mg/day in elderly fitness, 180 mg/day in soccer players, 360 mg/day in adolescent athletes, and 100 mg/day in the erectile-function pilot.

FenuFibers® (Fenugreek Fiber)

Satiety and weight support

Commonly a few grams of fenugreek fiber per day with meals.

Fenumannan® (Fenugreek Galactomannan Fiber)

Satiety and reduced food intake

An acute satiety trial used 4 g and 8 g of isolated fenugreek fiber, with 8 g working better; fenugreek gum glucose trials used about 6 to 16 g.

Guarana (Paullinia cupana)

Weight Management (Not Supported By The Cited Research)

Products typically supply 75-200 mg of extract (roughly 30-100 mg caffeine) or 500-1,500 mg of whole seed powder. Count its caffeine toward your daily total.

Kinetiq® (Bitter Orange Extract — Novel Ingredients)

Thermogenesis and weight management

About 50 mg of p-synephrine per day, the amount in the acute metabolic-rate study; the safety studies used 49 mg, and exercise trials used more, 3 mg/kg or 100 mg.

Pyruvate (Calcium Pyruvate / Sodium Pyruvate)

Modest body weight reduction

MODERN: 5-10 g/day Ca/Na pyruvate (Kalman 1999: 6 g/day × 6 wk). STANKO 1990s: 22-53

ChromeMate® (Niacin-Bound Chromium — Lonza)

Fat loss with muscle mass sparing

200 mcg elemental chromium/day is the typical supplement dose; the 1,000 mcg/day figure comes from a rat safety study, not a human efficacy trial.

Supresa® (Appetite and Crave Control)

Self-reported appetite decrease (69% vs 54% on placebo)

176.5 mg/day, as 88.25 mg twice daily with meals, the dose in the single 8-week trial. Saffron mood trials use a far lower 28-30 mg/day of a different extract, not evidence for this dose.

Phellodendron (Huang Bai)

Weight management in stress-eaters

RELORA® (Phellodendron + Magnolia): 250 mg × 3/day = 750 mg/day. PHELLODENDRON ALONE

Yohimbe / Yohimbine (Pausinystalia yohimbe)

Body fat: one small 21 day trial in athletes

The only non-drug trial cited used 20 mg/day of yohimbine for 21 days. Yohimbe bark supplements often contain far more or less yohimbine than the label states, so the amount you take is hard to predict.

Csat+® (Pharmactive Carob Extract)

Galactomannan fibre: the proposed satiety mechanism

No dose of Csat+ has been tested in people. No finished-product serving size is published; the two mouse studies fed the extract at 4.8% of total diet by weight, which gives no capsule dose.

Xanthigen® (Fucoxanthin + Pomegranate Seed Oil)

Weight loss in obese premenopausal women on a reduced-calorie diet

PIVOTAL: 600 mg Xanthigen®/day × 16 weeks (300 mg PSO + 300 mg brown seaweed extract

Yerba Mate (Ilex paraguariensis)

Weight Management Modest Effects

3 g a day of yerba mate capsules for 12 weeks in the only cited trial; supplements sold at 500 to 2,000 mg a day are below the amount that was tested.

MangoSelect® (African Mango Seed Extract)

Weight and waist support

150 mg twice daily before meals in two of the five trials (daily doses across trials ranged 300 mg to 1,050 mg); no dose has worked in a low risk of bias trial.

GyngerLean® (Ginger Weight Management Extract)

Appetite and hunger reduction

400–800 mg/day GyngerLean® standardized ginger extract; clinical studies at 400 mg tw

ZinjaBurn® (Dehydrozingerone)

Calorie burning has never been measured in anyone taking DHZ

No human dose has been studied; the supplier suggests 400 to 600 mg twice daily. The only animal regimen, 100 mg/kg/day in mice, scales to roughly 570 mg/day, below the label's 800 to 1200 mg/day.

EatLess® (Yeast-Hydrolysate Satiety Peptide — Anderson)

Appetite control

Commonly around 250 to 1,000 mg per day.

MitoBurn® (L-BAIBA)

Fat oxidation and body composition

250–500 mg/day; 500 mg is the full clinical dose

Zero-calorie sweetening with heat stability

ADI 5 mg/kg/day (FDA), 15 mg/kg/day (EU EFSA); typical product use 0-50 mg per serving.

NUTRALYS® Pea Protein (Roquette)

Complete Plant Protein Profile

20-50 g/day pea protein for muscle/sports applications; per product specification for

Resistant Starch

Reduced fasting insulin and HOMA-IR

GUT/MICROBIOME: 15-30 g/day (1-2 tbsp Hi-Maize® or raw potato starch). T2D METABOLIC:

Benexia® (Chia Seed — Salvia hispanica)

Commonly 15 to 25 grams of chia per day.

Modest weight and body-fat support

250 mg twice daily, 50% chlorogenic acids

Chlorogenic Acid

Modest blood pressure reduction

BP: 140 mg/day green coffee bean × 4 wk. WEIGHT: 500 mg/day GBCE ≥30% CGA → -1.30 kg

Gynostemma pentaphyllum (Jiaogulan / Southern Ginseng)

Blood sugar: studied in people with type 2 diabetes

200 to 450 mg standardized extract daily, or 3 to 9 g a day of dried herb as tea; the diabetes trial used 6 g a day. Products and doses studied differ, so results may not transfer.

Equivalent to whey for muscle and strength gains

MUSCLE/RT: 20-40 g/day. FDA HEART CLAIM: 25 g/day. Anderson 1995 NEJM meta 38 trials:

ApplePhenon® (Apple Polyphenol Extract — BGG)

Visceral fat: a subgroup finding in a 94 person beverage study

600 mg/day in the 12 week metabolic studies; the brand-named trial used 1200 mg/day; one study included an 1800 mg/day arm to check excessive intake.

Cactinea® (Prickly Pear / Opuntia ficus-indica)

Water Elimination / Reduced Sensation of Heavy, Swollen Legs

200-400 mg/day standardized extract (research dose)

Chitin-Glucan Fiber (Fungal, Aspergillus niger; Kitozyme)

Post-meal blood sugar and triglycerides

Around 1.5 to 4.5 grams per day with meals.

Modest fat absorption reduction

Doses varied across trials and no single dose is established; taken with or just before fat-containing meals, and even at studied doses the effect on body weight was minimal.

Bulk sugar replacement with zero glycemic impact

5-30 g per serving as a sugar substitute; most adults tolerate roughly 50 g at one time, though 30 g produced a large rise in blood erythritol lasting more than 2 days in an 8-person pilot.

Factor21® (Bitter Melon Extract — Verdure Sciences)

Healthy blood sugar

Per the product specification.

FucoVital® (Microalgae Fucoxanthin — Algatech)

Metabolic support

No established dose for FucoVital itself, as no trial of it is cited; in the Xanthigen trial, energy expenditure rose at fucoxanthin above 2.4 mg per day, a product also containing pomegranate seed oil.

GlucoVantage® (Dihydroberberine)

Better absorbed than standard berberine (five person pilot)

100–200 mg/day before meals; the only human study gave single 100 mg or 200 mg doses, so no trial has established an effective daily dose.

InSea2® (Brown Seaweed Polyphenols — InnoVactiv)

Gentler post-meal glucose

About 500 mg taken before a carbohydrate-containing meal.

Lactobacillus gasseri

Abdominal fat: one trial, one strain, in fermented milk

The one cited trial used strain SBT2055 delivered daily in fermented milk, not a capsule; there is no established consumer dose for L. gasseri.

LuraLean® (Glucomannan Fiber Blend — AHD International)

Small average weight difference in konjac fiber trials

Per LuraLean product specification (typical 2-4 g/day)

Prenulin® (L-Arabinose and Chromium — Pharmachem)

Post-meal blood sugar

No dose of Prenulin itself has been tested in a published study. Cited studies used L-arabinose and 600 mcg/day chromium picolinate; amounts in finished products vary and may not match.

α-Lacys Reset® (Alpha-Lipoic Acid and Cysteine Complex — Nutraceutics)

Antioxidant and redox support

Used at about 25 mg per day in finished formulas, far below the 300 to 1800 mg per day alpha-lipoic acid doses in the weight-loss trials. No trial shows 25 mg reproduces those results.

Alluvia® (Purple Tea Extract — Maypro)

Fat-metabolism support

Commonly around 100 to 400 mg per day.

FB3 Fusion® (Fat-Absorption Botanical Blend — Bio Actives Japan)

What the Coleus forskohlii trial measured

Per the product specification.

Guggul (Commiphora mukul)

Cholesterol: the largest trial found LDL went UP

Trials tested 50 mg guggulipid twice daily, 1,000 or 2,000 mg three times daily, and 2,160 mg a day; no dose has reliably lowered cholesterol in a Western trial.

Stimulant/sympathomimetic effects (animal evidence)

No human dose established; labels commonly list 25 to 100 mg per serving, but these are marketing amounts, not amounts shown to do anything in a human trial of hordenine on its own.