Fibersol® (Digestion-Resistant Maltodextrin — ADM/Matsutani)

Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

Fibersol® is a digestion-resistant maltodextrin, a soluble prebiotic fiber made from cornstarch, co-developed by ADM and Matsutani. It dissolves clear and tasteless, making it easy to add to foods and drinks, and is studied for supporting satiety, healthy blood sugar, and regularity.

Studied Dose Acute satiety and glycemic trials used 6 to 10 g per dose; the visceral-fat trials used 15 to 27 g per day in three divided doses.
Active Compound Digestion-resistant maltodextrin, a soluble dietary fiber that resists digestion and is partly fermented in the colon.

Benefits

Satiety and appetite

In clinical research, the soluble fiber reduced hunger and increased fullness, supporting appetite control and weight management.

Healthy blood sugar

Fibersol can blunt the rise in blood sugar and insulin after meals, supporting steadier post-meal glucose.

Regularity and gut health

As a fermentable soluble fiber, it is fermented in the colon to short-chain fatty acids such as butyrate and can raise beneficial bacteria like bifidobacteria. Effects on stool frequency in healthy adults are modest.

Mechanism of action

1

Soluble fiber bulking

The resistant maltodextrin adds soluble bulk that slows gastric emptying and nutrient absorption, supporting fullness and steadier glucose.

2

Colonic fermentation

Part of the fiber is fermented into short-chain fatty acids that nourish the colon and support a healthy microbiome.

Clinical trials

1
Resistant Maltodextrin and Satiety — Study
PubMed

Study of the soluble dietary fiber Fibersol-2 on hunger and satiety. (Ye et al. 2015, Nutrition Research)

Adults.

The soluble fiber decreased hunger and increased satiety versus control, supporting its appetite and weight-management uses.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — well tolerated even at higher fiber intakes.
Mild gas or bloating can occur as intake rises.
Increase the dose gradually.

Important Drug interactions

Diabetes medication — fiber may affect blood sugar; monitor.
May slow absorption of some medications; separate dosing if advised.
Tell your doctor if you have a digestive condition.

Frequently asked questions about Fibersol® (Digestion-Resistant Maltodextrin — ADM/Matsutani)

What is Fibersol?

Fibersol® is a digestion-resistant maltodextrin, a soluble prebiotic fiber made from cornstarch, co-developed by ADM and Matsutani. It dissolves clear and tasteless, making it easy to add to foods and drinks, and is studied for supporting satiety, healthy blood sugar, and regularity.

What is Fibersol used for?

Fibersol is researched primarily for Gut Health and Weight Management. In clinical research, the soluble fiber reduced hunger and increased fullness, supporting appetite control and weight management.

What is the recommended dosage of Fibersol?

The clinically studied dose is Acute satiety and glycemic trials used 6 to 10 g per dose; the visceral-fat trials used 15 to 27 g per day in three divided doses. Always follow the product label and check with a healthcare provider for personal advice.

Is Fibersol safe, and does it have side effects?

For most healthy adults, Fibersol is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — well tolerated even at higher fiber intakes. Mild gas or bloating can occur as intake rises. It may also interact with some medications. Fibersol is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Fibersol interact with any medications?

Possible interactions include: Diabetes medication — fiber may affect blood sugar; monitor. May slow absorption of some medications; separate dosing if advised. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Fibersol?

NutraSmarts rates the evidence for Fibersol as Moderate (3 out of 5). It is backed by 1 clinical trial and 5 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(5 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Ye Z, Arumugam V, Haugabrooks E, et al. Soluble dietary fiber (Fibersol-2) decreased hunger and increased satiety hormones in humans. Nutr Res. 2015;35(5):393-400..PubMedUsed to support: Randomized double-blind placebo-controlled crossover trial in 19 healthy adults: 10 g of Fibersol-2 taken with a meal delayed hunger and increased fullness for 1.5 to 2 hours and raised the satiety hormones peptide YY and GLP-1, while 5 g had no effect. It measured appetite ratings and hormones, not body weight. One author is employed by the manufacturer.
  2. Livesey G, Tagami H. Interventions to lower the glycemic response to carbohydrate foods with a low-viscosity fiber (resistant maltodextrin): meta-analysis of randomized controlled trials. Am J Clin Nutr. 2009;89(1):114-25. doi: 10.3945/ajcn.26842.PubMedUsed to support: Meta-analysis of 37 randomized placebo-controlled trials in healthy adults: about 6 g of resistant maltodextrin lowered the post-meal blood glucose rise by roughly 10 to 20 percent, dose-dependently, with a larger effect in drinks than in solid foods. One co-author is affiliated with the manufacturer of the fiber.
  3. Hashizume C, Kishimoto Y, Kanahori S, Yamamoto T, Okuma K, Yamamoto K. Improvement effect of resistant maltodextrin in humans with metabolic syndrome by continuous administration. J Nutr Sci Vitaminol (Tokyo). 2012;58(6):423-30. doi: 10.3177/jnsv.58.423.PubMedUsed to support: Randomized double-blind placebo-controlled trial in 30 adults with metabolic syndrome: 9 g of resistant maltodextrin taken three times daily for 12 weeks significantly reduced waist circumference, visceral fat area, insulin resistance (HOMA-R) and triglycerides versus placebo over time. Fasting glucose fell within the treatment group. The trial was small and run by the fiber's manufacturer.
  4. Kitagawa M, Nakagawa S, Suzuki T, Kishimoto Y, Kanahori S, Hatakeyama Y, Tomita S, Fukuhara I. Visceral Fat-Reducing Effect and Safety of Continuous Consumption of Beverage Containing Resistant Maltodextrin: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Clinical Trial. J Nutr Sci Vitaminol (Tokyo). 2020;66(5):417-426. doi: 10.3177/jnsv.66.417.PubMedUsed to support: Randomized double-blind placebo-controlled trial in 140 healthy adults: 5 g of resistant maltodextrin three times daily for 12 weeks produced a small but significant fall in abdominal visceral fat area versus placebo, with no adverse blood or urine findings. Funded by the fiber's manufacturer and a beverage company.
  5. Fastinger ND, Karr-Lilienthal LK, Spears JK, Swanson KS, Zinn KE, Nava GM, Ohkuma K, Kanahori S, Gordon DT, Fahey GC Jr. A novel resistant maltodextrin alters gastrointestinal tolerance factors, fecal characteristics, and fecal microbiota in healthy adult humans. J Am Coll Nutr. 2008;27(2):356-66. doi: 10.1080/07315724.2008.10719712.PubMedUsed to support: Randomized double-blind study in 38 healthy adults: Fibersol-2 was well tolerated and shifted colonic fermentation toward butyrate and altered fecal bacterial populations, tending to raise bifidobacteria, with only minor effects on digestive tolerance.