Benefits
Carbohydrate blocking
By inhibiting starch-digesting alpha-amylase, the extract reduces the sugar and calories absorbed from starchy foods.
Weight management
White kidney bean alpha-amylase inhibitors have supported weight and fat loss in randomized research as part of a calorie-controlled approach. A 2026 meta-analysis of 8 trials in 543 people found about 1.6 kg more weight loss than placebo, while an earlier review found no significant weight difference and judged the trials available at the time to be seriously flawed.
Post-meal glucose: limited and mixed evidence
Slower starch digestion would be expected to blunt the rise in blood sugar after a starchy meal, and small studies point both ways. A 12-person crossover trial of a different purified bean extract lowered the glucose rise after a mixed meal, while a 13-person study of Phase 2 lowered the glycemic index of white bread only at the largest 3 g powder dose. Longer trials, including the 12-week study cited here, have not shown changes in HbA1c or fasting blood sugar.
Mechanism of action
Alpha-amylase inhibition
Phaseolamin binds and temporarily inactivates alpha-amylase, slowing the breakdown of starch into absorbable sugars.
Reduced caloric absorption
With less starch digested in the small intestine, some passes onward undigested, lowering the meal's effective calorie load.
Clinical trials
12-week double-blind placebo-controlled randomized trial of Phase 2, Ashland's branded white kidney bean alpha-amylase inhibitor, at 700 mg or 1,000 mg three times a day, 30 minutes before meals. It tested that brand, not CarbLite. The study was sponsored by InQpharm, the ingredient was supplied by Pharmachem, and two authors are consultants to Ashland. (Jäger et al. 2024, Scientific Reports)
81 adults with overweight or moderate obesity who completed the study, all following a calorie-restricted diet about 20 percent below their calculated energy needs.
On top of the calorie-restricted diet, the 1,000 mg group lost 4.48 kg against 0.54 kg on placebo, and 3.17 kg of fat mass against 0.65 kg. The 700 mg group lost 3.18 kg of weight, but its fat mass change did not separate from placebo (p = 0.268). Total cholesterol, LDL, HDL and HbA1c were no different from placebo. Participants and investigators rated tolerability as good or very good.