Home Ingredients Slendacor® (Botanical Blend for Weight Management)
Weight Management

Slendacor® (Botanical Blend for Weight Management)

Evidence Level
Limited
1 Clinical Trial
5 Documented Benefits
2/5 Evidence Score

Slendacor® is a proprietary botanical blend sold by PLT Health Solutions, developed at Laila Impex / Laila Nutraceuticals and identified in the research literature as LI85008F. It combines Moringa oleifera leaf, curry leaf (Murraya koenigii) and turmeric (Curcuma longa) rhizome extracts in a 6:3:1 ratio. Two randomized, double-blind, placebo-controlled trials of this exact blend, both run by staff of the companies that develop and sell it, reported reductions in body weight, BMI and waist circumference in overweight and obese adults who were also on a calorie-controlled diet and walking daily. No independent group has replicated the result.

Studied Dose 900 mg/day by mouth: two divided doses for 16 weeks (Dixit 2018), three divided doses for 8 weeks (Sengupta 2012).
Active Compound Moringa oleifera leaf, Murraya koenigii (curry leaf) leaf and Curcuma longa (turmeric) rhizome extracts in a 6:3:1 ratio, turmeric standardized to 95% total curcuminoids; research code LI85008F.

Benefits

Body Weight and BMI Reduction

In a 16-week double-blind randomized trial in 140 overweight adults (BMI 27 to 29.9, ages 21 to 50), the group taking 900 mg/day of the blend lost 5.36 kg against 0.87 kg on placebo, and BMI fell 2.05 against 0.34 kg/m2 (both p<0.0001). Everyone in the trial, both arms, also followed a roughly 1800 kcal/day diet and walked 30 minutes five days a week, so this is the effect on top of diet and exercise. The trial was co-authored by staff of the company that developed the ingredient and the company that sells it.

Supported by Trial 1

Waist and Hip Circumference

The same trial reported significant reductions in waist and hip circumference in the supplemented group, and a 2.08-fold reduction of the waist/hip ratio. Visceral fat itself was not measured: there was no imaging and no body-composition scan, so the finding is a change in tape-measure girth.

Supported by Trial 1

Blood Lipid and Glucose Changes

In the 16-week trial LDL cholesterol fell and HDL rose compared with placebo, improving the LDL/HDL ratio; in the 8-week trial the supplemented group had lower fasting blood glucose, LDL, LDL/HDL ratio and triglycerides. Fat mass and body composition were not measured in either human trial: the reductions in fat mass and fat-cell size come from a study in high-fat-diet-fed rats.

Supported by Trial 1

Multi-Botanical Mechanism

The three botanicals are proposed to act on fat cells through different pathways, but the work behind that proposal is in rats and in cultured 3T3-L1 fat cells, not in people. The human trials measured weight and blood markers only, so how the blend produces its effect is not established in humans.

Supported by Trial 1

Fixed 6:3:1 Botanical Blend (LI85008F)

Slendacor is PLT Health Solutions' fixed-ratio blend of Moringa oleifera leaf, Murraya koenigii (curry leaf) and Curcuma longa (turmeric) rhizome extracts, combined in a 6:3:1 ratio with the turmeric extract standardized to 95% total curcuminoids. It was developed at Laila Impex / Laila Nutraceuticals in India and appears in the published research under the code LI85008F, and in the 2012 trial under the name Adipromin. Both human trials used this same 900 mg/day preparation, so the results apply to this specific blend rather than to the three botanicals taken separately.

Supported by Trial 1

Mechanism of action

1

Moringa oleifera Activity

Moringa leaves provide polyphenols, isothiocyanates (similar to broccoli), and other bioactives; documented metabolic and anti-inflammatory effects.

2

Murraya koenigii (Curry Leaf) Activity

Curry leaves contain alkaloids (mahanimbine, koenimbine), polyphenols; documented effects on lipid metabolism and oxidative stress.

3

Curcuma longa (Turmeric) Activity

Turmeric rhizome provides curcuminoids (curcumin) and other polyphenols; documented anti-inflammatory and metabolic effects.

4

Combined Anti-Inflammatory and Metabolic

The combined anti-inflammatory and metabolic action is proposed from rat and cell studies. Both human trials tested only the finished blend against placebo, with no arm receiving the individual botanicals, so any synergy between the three extracts is untested in people.

Clinical trials

1
Slendacor (LI85008F) 16-Week Randomized, Double-Blind, Placebo-Controlled Trial, Manufacturer-Affiliated (Dixit 2018)
PubMed

Randomized, double-blind, placebo-controlled trial of 900 mg/day of the blend in two divided doses against placebo, in 140 overweight adults (BMI 27 to 29.9, ages 21 to 50, 29.3% male) for 16 weeks. Both arms followed a roughly 1800 kcal/day diet and walked 30 minutes five days a week.

140 overweight adults.

Body weight fell 5.36 kg on the blend against 0.87 kg on placebo, and BMI fell 2.05 against 0.34 kg/m2, both p<0.0001. Waist and hip circumference fell significantly in the supplemented group, with a 2.08-fold reduction of the waist/hip ratio, and the LDL/HDL ratio improved against placebo. No major adverse events were reported. The author list includes staff of Laila Nutraceuticals, which developed the blend, and PLT Health Solutions, which sells it.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Mild GI distress.
Allergic reactions to any of the component botanicals rare.
Turmeric may cause mild GI upset or loose stools in some people at higher intakes.
Neither published trial reported major adverse events, over 8 weeks and 16 weeks respectively. There is no human safety data beyond 16 weeks of use.

Important Drug interactions

Diabetes medications — modest hypoglycemic effects.
Antihypertensives — modest BP effects.
Anticoagulants — modest effects from polyphenols.
Pregnancy/lactation — limited safety data; avoid supplementation.
Gallbladder conditions — turmeric may stimulate bile flow; use caution.
Children — not appropriate for pediatric weight management without medical supervision.

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Frequently asked questions about Slendacor® (Botanical Blend for Weight Management)

What is Slendacor?

Slendacor® is a proprietary botanical blend sold by PLT Health Solutions, developed at Laila Impex / Laila Nutraceuticals and identified in the research literature as LI85008F. It combines Moringa oleifera leaf, curry leaf (Murraya koenigii) and turmeric (Curcuma longa) rhizome extracts in a 6:3:1 ratio.

What is Slendacor used for?

Slendacor is researched primarily for Weight Management. In a 16-week double-blind randomized trial in 140 overweight adults (BMI 27 to 29.9, ages 21 to 50), the group taking 900 mg/day of the blend lost 5.36 kg against 0.87 kg on placebo, and BMI fell 2.05 against 0.34 kg/m2 (both p<0.0001).

What is the recommended dosage of Slendacor?

The clinically studied dose is 900 mg/day by mouth: two divided doses for 16 weeks (Dixit 2018), three divided doses for 8 weeks (Sengupta 2012). Always follow the product label and check with a healthcare provider for personal advice.

Is Slendacor safe, and does it have side effects?

For most healthy adults, Slendacor is well tolerated at studied doses. Reported effects can include: Generally well-tolerated. Mild GI distress. It may also interact with some medications. Slendacor is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Slendacor interact with any medications?

Possible interactions include: Diabetes medications — modest hypoglycemic effects. Antihypertensives — modest BP effects. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Slendacor?

NutraSmarts rates the evidence for Slendacor as Limited (2 out of 5). It is backed by 1 clinical trial and 3 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(3 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Dixit K, Kamath DV, Alluri KV, Davis BA Efficacy of a novel herbal formulation for weight loss demonstrated in a 16-week randomized, double-blind, placebo-controlled clinical trial with healthy overweight adults Diabetes, Obesity and Metabolism. 2018;20(11):2633-2641. doi: 10.1111/dom.13443.PubMedUsed to support: A 16-week double-blind, placebo-controlled randomized trial in 140 healthy overweight adults (BMI 27 to 29.9, ages 21 to 50) of 900 mg/day LI85008F, the Moringa oleifera plus Murraya koenigii plus Curcuma longa blend sold as Slendacor. The supplemented group lost 5.36 kg against 0.87 kg on placebo, and BMI fell 2.05 against 0.34 kg/m2, both p<0.0001, with significant reductions in waist and hip circumference, a 2.08-fold reduction of the waist/hip ratio, and an improved LDL/HDL ratio against placebo. Both arms also followed a roughly 1800 kcal/day diet and walked 30 minutes five days a week, so the result is an effect on top of diet and exercise. The authors include staff of Laila Nutraceuticals, which developed the blend, and PLT Health Solutions, which sells it; no independent group has repeated the trial.
  2. Sengupta K, Mishra AT, Rao MK, Sarma KVS, Krishnaraju AV, Trimurtulu G Efficacy and tolerability of a novel herbal formulation for weight management in obese subjects: a randomized double blind placebo controlled clinical study Lipids in Health and Disease. 2012;11:122. doi: 10.1186/1476-511X-11-122.PubMedUsed to support: An 8-week double-blind, placebo-controlled randomized trial (ISRCTN37381706) of 900 mg/day LI85008F, there called Adipromin, in 50 obese adults (25 per arm, BMI 30 to 40, ages 27 to 50). Both arms also followed a 2000 kcal/day diet and walked 30 minutes five days a week. The supplemented group showed significant net reductions in body weight and BMI against placebo, and had lower fasting blood glucose, LDL, LDL/HDL ratio and triglycerides, with a 21.26% rise in serum adiponectin (p=0.012). No major adverse events were reported. The paper states the study was funded by Laila Impex R&D Center, which developed the blend, and three of its authors were employees there, so it is not an independent confirmation of the later 16-week trial.
  3. Kundimi S, et al. Combined extracts of Moringa oleifera, Murraya koenigii leaves, and Curcuma longa rhizome increases energy expenditure and controls obesity in high-fat diet-fed rats Lipids in Health and Disease. 2020;19(1):198. doi: 10.1186/s12944-020-01376-7.PubMedUsed to support: A study in rats fed a high-fat diet, not a trial in people. LI85008F, the same Moringa oleifera plus Murraya koenigii plus Curcuma longa blend sold as Slendacor, reduced body weight gain, fat mass, fat-cell size, liver weight and liver triglycerides, with changes in markers of heat production and fat breakdown. Animal results do not establish that the blend changes body composition in humans, and body composition was not measured in either human trial.