Benefits
Weight management
A pooled analysis of three small, short-term trials (103 adults in total) found green coffee extract providing at least 500 mg/day of chlorogenic acid reduced body weight by about 1.3 kg versus control. The effect is small, the trials were brief, and the field is dominated by low-quality industry-funded studies, so this is not an established fat-loss result.
Blood sugar (mechanism only)
Chlorogenic acid slows carbohydrate absorption in laboratory and short mechanistic studies. No blood-sugar or metabolic outcome is shown in the trial cited on this page.
Antioxidant defense
Chlorogenic acid is a polyphenol with antioxidant activity in laboratory tests. No antioxidant outcome has been measured in people in the trial cited here.
Mechanism of action
Chlorogenic acid action
Chlorogenic acid is studied for slowing carbohydrate absorption and supporting glucose and fat metabolism.
Antioxidant action
The polyphenol scavenges free radicals and supports antioxidant defenses.
Clinical trials
Systematic review and meta-analysis of chlorogenic acid in green coffee on body weight. (Kanchanasurakit et al. 2023, Systematic Reviews)
Adults across multiple trials.
Across three small, short-term randomized trials (103 adults total), green coffee extract providing at least 500 mg/day of chlorogenic acid lowered body weight by about 1.3 kg versus control.