Home Ingredients SlimPro® (Fish Protein Hydrolysate — Compagnie des Pêches Saint-Malo)
Weight Management

SlimPro® (Fish Protein Hydrolysate — Compagnie des Pêches Saint-Malo)

Micromesistius poutassou
Evidence Level
Limited
1 Clinical Trial
3 Documented Benefits
2/5 Evidence Score

SlimPro is a fish protein hydrolysate made from the muscle of blue whiting (Micromesistius poutassou) by enzymatic hydrolysis, developed by Compagnie des Pêches Saint-Malo. It supplies small marine peptides that have been studied for their effect on the body's own appetite-regulating gut hormones. In a single controlled trial in slightly overweight adults, taking the hydrolysate alongside a mild reduced-calorie diet raised blood levels of the satiety hormones cholecystokinin (CCK) and GLP-1 and was associated with greater reductions in body weight, fat mass, and body circumferences than placebo over 90 days. No added effect was seen at the higher of the two doses tested. The evidence to date comes from this one manufacturer-affiliated study, so it is best viewed as a supportive part of a reduced-calorie routine rather than a proven stand-alone aid.

Studied Dose Around 1.4 grams per day.
Active Compound A hydrolysate of blue whiting fish protein, providing bioactive peptides that stimulate satiety hormones.

Benefits

Appetite-regulating hormone support

In a controlled trial, the fish protein hydrolysate raised blood levels of the satiety hormones cholecystokinin (CCK) and GLP-1 compared with placebo. These gut hormones signal fullness to the brain, which is how the peptides are thought to support appetite regulation.

Supported by Trial 1

Body composition support

Taken alongside a mild reduced-calorie diet, the hydrolysate was associated with greater reductions in body weight, fat mass, and waist, hip, and thigh circumference than placebo over 90 days in slightly overweight adults.

Supported by Trial 1

Weight management

By supporting the body's own satiety signals, it is used as one part of a reduced-calorie weight-management routine rather than as a stand-alone solution.

Supported by Trial 1

Mechanism of action

1

Gut hormone stimulation

The bioactive peptides trigger enteroendocrine cells to release cholecystokinin (CCK) and GLP-1, hormones that signal fullness to the brain.

2

Reduced hunger signaling

Higher satiety-hormone activity is thought to lower the drive to eat, supporting smaller portions at meals.

Clinical trials

1
Fish protein hydrolysate, body composition, and satiety hormones (RCT)
PubMed

Randomized placebo-controlled study of a blue whiting fish protein hydrolysate at 1.4 and 2.8 grams on body composition and satiety-hormone levels. (Nobile et al. 2016, Food and Nutrition Research)

120 slightly overweight adults (BMI 25 to 30) on a mild reduced-calorie diet.

Over 90 days, both the 1.4 and 2.8 gram doses produced greater reductions in body weight, fat mass, and body circumferences than placebo and raised blood CCK and GLP-1 levels; the two doses did not differ, and placebo also lost some weight from the diet alone.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Mild digestive upset is occasionally reported.
People with fish allergy should avoid it.

Important Drug interactions

Diabetes medication: appetite and glucose effects may interact; monitor.
Take before meals for the intended satiety effect.
Tell your doctor if you manage blood sugar.

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Frequently asked questions about SlimPro® (Fish Protein Hydrolysate — Compagnie des Pêches Saint-Malo)

What is SlimPro?

SlimPro is a fish protein hydrolysate made from the muscle of blue whiting (Micromesistius poutassou) by enzymatic hydrolysis, developed by Compagnie des Pêches Saint-Malo. It supplies small marine peptides that have been studied for their effect on the body's own appetite-regulating gut hormones.

What is SlimPro used for?

SlimPro is researched primarily for Weight Management. In a controlled trial, the fish protein hydrolysate raised blood levels of the satiety hormones cholecystokinin (CCK) and GLP-1 compared with placebo.

What is the recommended dosage of SlimPro?

The clinically studied dose is Around 1.4 grams per day. Always follow the product label and check with a healthcare provider for personal advice.

Is SlimPro safe, and does it have side effects?

Side effects and cautions reported for SlimPro include: Generally well-tolerated. Mild digestive upset is occasionally reported. It may also interact with some medications. SlimPro is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does SlimPro interact with any medications?

Possible interactions include: Diabetes medication: appetite and glucose effects may interact; monitor. Take before meals for the intended satiety effect. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for SlimPro?

NutraSmarts rates the evidence for SlimPro as Limited (2 out of 5). It is backed by 1 study summary and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Nobile V, Duclos E, Michelotti A, Bizzaro G, Negro M, Soisson F. Supplementation with a fish protein hydrolysate (Micromesistius poutassou): effects on body weight, body composition, and CCK/GLP-1 secretion. Food Nutr Res. 2016;60:29857. doi: 10.3402/fnr.v60.29857..PubMedUsed to support: Placebo-controlled randomized trial in 120 slightly overweight adults; both 1.4 and 2.8 gram doses improved body composition and raised CCK and GLP-1 versus placebo, with no difference between doses. Two of the authors are employed by the ingredient's manufacturer.