Home Ingredients NEOBEE® (Medium-Chain Triglycerides — Stepan)
Weight ManagementMetabolic HealthEnergy

NEOBEE® (Medium-Chain Triglycerides — Stepan)

Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

NEOBEE® is a line of medium-chain triglycerides (MCTs) from Stepan, fats made of shorter fatty-acid chains than typical dietary fat. MCTs are absorbed and burned quickly for energy rather than stored, and are studied for supporting body composition and providing fast, usable fuel.

Studied Dose Commonly 10 to 20 grams per day with meals.
Active Compound Medium-chain triglycerides (MCTs), primarily caprylic (C8) and capric (C10) fatty acids.

Benefits

Body composition

A meta-analysis of randomized trials found that replacing long-chain fats with medium-chain triglycerides supported modest reductions in body weight and fat mass.

Supported by Trial 1

Fast energy

MCTs are rapidly absorbed and converted to energy, providing a quick fuel source for the body (and, via ketones, the brain).

Supported by Trial 1

Ketone production

MCTs are readily turned into ketones, an alternative fuel of interest for energy and cognitive support.

Supported by Trial 1

Mechanism of action

1

Rapid absorption

Because of their shorter chain length, MCTs are absorbed directly into the portal blood and sent to the liver, bypassing the slower route of long-chain fats.

2

Preferential oxidation

The liver readily burns MCTs for energy or converts them to ketones rather than storing them as body fat.

Clinical trials

1
Medium-Chain Triglycerides and Body Composition — Meta-Analysis
PubMed

Meta-analysis of randomized controlled trials of medium-chain triglycerides on weight loss and body composition. (Mumme and Stonehouse 2015, Journal of the Academy of Nutrition and Dietetics)

Adults across multiple RCTs.

Replacing long-chain fats with MCTs supported modest reductions in body weight and fat mass.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — digestive symptoms are most common.
Taking too much at once can cause cramping, nausea, or loose stools.
Start with a small amount and take with food.

Important Drug interactions

Generally compatible with medications.
People with liver disease should consult a doctor before using concentrated MCTs.
Tell your doctor if you follow a ketogenic protocol for a medical condition.

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Frequently asked questions about NEOBEE® (Medium-Chain Triglycerides — Stepan)

What is NEOBEE?

Neobee® is a line of medium-chain triglycerides (MCTs) from Stepan, fats made of shorter fatty-acid chains than typical dietary fat. MCTs are absorbed and burned quickly for energy rather than stored, and are studied for supporting body composition and providing fast, usable fuel.

What is NEOBEE used for?

NEOBEE is researched primarily for Weight Management, Metabolic Health, and Energy. A meta-analysis of randomized trials found that replacing long-chain fats with medium-chain triglycerides supported modest reductions in body weight and fat mass.

What is the recommended dosage of NEOBEE?

The clinically studied dose is Commonly 10 to 20 grams per day with meals. Always follow the product label and check with a healthcare provider for personal advice.

Is NEOBEE safe, and does it have side effects?

For most healthy adults, NEOBEE is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — digestive symptoms are most common. Taking too much at once can cause cramping, nausea, or loose stools. It may also interact with some medications. NEOBEE is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does NEOBEE interact with any medications?

Possible interactions include: Generally compatible with medications. People with liver disease should consult a doctor before using concentrated MCTs. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for NEOBEE?

NutraSmarts rates the evidence for NEOBEE as Moderate (3 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Mumme K, Stonehouse W. Effects of medium-chain triglycerides on weight loss and body composition: a meta-analysis of randomized controlled trials. J Acad Nutr Diet. 2015;115(2):249-263..PubMedUsed to support: Meta-analysis supporting body-composition benefit of MCTs.