Fabenol® (White Kidney Bean Extract — Indena)

Phaseolus vulgaris
Evidence Level
Limited
1 Clinical Trial
3 Documented Benefits
2/5 Evidence Score

Fabenol® is a standardized white kidney bean (Phaseolus vulgaris) extract from Indena that inhibits alpha-amylase, the enzyme that digests starch. By temporarily slowing starch breakdown, it reduces the sugar and calories absorbed from starchy meals, supporting weight and carbohydrate management.

Studied Dose Around 500 mg to 1 g taken before a starchy meal.
Active Compound Standardized Phaseolus vulgaris (white kidney bean) extract containing alpha-amylase-inhibiting phaseolamin.

Benefits

Weight and adiposity

In a randomized controlled trial, white kidney bean extract supported reductions in body weight and body fat as part of a calorie-controlled approach.

Carbohydrate management

By slowing starch digestion, it lowers the sugar and calories absorbed from a starchy meal. This is an acute mechanism; in pooled trials fasting glucose was unchanged versus placebo.

Appetite and energy steadiness

Slower carbohydrate absorption may help even out post-meal energy, but appetite and fullness were not measured in the trials.

Mechanism of action

1

Alpha-amylase inhibition

Phaseolamin binds the digestive enzyme alpha-amylase, temporarily reducing its ability to break starch into absorbable sugars.

2

Reduced starch absorption

With less starch digested in the upper gut, some passes further along, lowering the meal's caloric and glycemic load.

Clinical trials

1
White Kidney Bean Extract and Weight: Meta-Analysis of 8 Trials (generic extract, not Fabenol)
PubMed

Systematic review and meta-analysis of 8 randomized trials of oral white kidney bean extract (n=543) on body weight and adiposity. This is pooled generic-extract evidence, not a trial of Fabenol. (Shi et al. 2026, Nutrition Research)

Overweight adults.

Across 8 trials (543 adults), extract cut body weight by about 1.6 kg, BMI by 0.6, and fat mass by 1.2 kg versus placebo. Fasting glucose, triglycerides and insulin did not differ from placebo.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — digestive symptoms are the most common.
Mild gas, bloating, or loose stools can occur from undigested starch.
Take with starchy meals to assess tolerance.

Important Drug interactions

Diabetes medication — may add to blood-sugar lowering; monitor.
Take with starchy meals, not pure protein or fat meals, for the intended effect.
Tell your doctor if you manage blood sugar with medication.

Frequently asked questions about Fabenol® (White Kidney Bean Extract — Indena)

What is Fabenol?

Fabenol® is a standardized white kidney bean (Phaseolus vulgaris) extract from Indena that inhibits alpha-amylase, the enzyme that digests starch. By temporarily slowing starch breakdown, it reduces the sugar and calories absorbed from starchy meals, supporting weight and carbohydrate management.

What is Fabenol used for?

Fabenol is researched primarily for Weight Management. In a randomized controlled trial, white kidney bean extract supported reductions in body weight and body fat as part of a calorie-controlled approach.

What is the recommended dosage of Fabenol?

The clinically studied dose is Around 500 mg to 1 g taken before a starchy meal. Always follow the product label and check with a healthcare provider for personal advice.

Is Fabenol safe, and does it have side effects?

For most healthy adults, Fabenol is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — digestive symptoms are the most common. Mild gas, bloating, or loose stools can occur from undigested starch. It may also interact with some medications. Fabenol is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Fabenol interact with any medications?

Possible interactions include: Diabetes medication — may add to blood-sugar lowering; monitor. Take with starchy meals, not pure protein or fat meals, for the intended effect. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Fabenol?

NutraSmarts rates the evidence for Fabenol as Limited (2 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Shi N, Wang R, Cao X, et al. White kidney bean extract reduces body weight and adiposity with acceptable safety in adults with overweight and obese: a systematic review and meta-analysis. Nutr Res. 2026;150:49-61..PubMedUsed to support: Systematic review and meta-analysis of 8 randomized trials of oral generic white kidney bean extract (n=543) found modest reductions in body weight (about 1.6 kg), BMI, fat mass and waist versus placebo, with no significant change in fasting glucose, triglycerides or insulin; this is generic-extract evidence, not a trial of Fabenol.