Home Ingredients FB3 Fusion® (Fat-Absorption Botanical Blend — Bio Actives Japan)
Weight ManagementMetabolic Health

FB3 Fusion® (Fat-Absorption Botanical Blend — Bio Actives Japan)

Evidence Level
Limited
0 Clinical Trials
3 Documented Benefits
2/5 Evidence Score

FB3 Fusion® is a weight-management blend from Bio Actives Japan and American Medical Holdings that combines three standardized botanicals, Coleus forskohlii, Salacia reticulata, and sesame (Sesamum indicum). Together they are designed to reduce the absorption of dietary fat and support healthy body composition. Published data for the specific blend are limited.

Studied Dose Per the product specification.
Active Compound Blend of Coleus forskohlii (forskolin), Salacia reticulata (kotanol), and Sesamum indicum (sesamin).

Benefits

Reduced fat absorption

FB3 Fusion is designed to inhibit the absorption of some dietary fat, supporting weight management as part of a calorie-controlled approach.

Body-composition support

By limiting fat absorption and supporting fat metabolism, the blend is positioned to help maintain a healthy body composition.

Limited-evidence note

Each botanical has individual research, but dedicated published clinical data for the specific finished blend are limited.

Mechanism of action

1

Lipase inhibition

Salacia and the blend's botanicals are studied for inhibiting fat-digesting lipase enzymes, so less dietary fat is absorbed.

2

Fat-metabolism support

Forskolin from Coleus and sesamin from sesame are studied for supporting fat breakdown and metabolism.

Clinical trials

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Mild digestive upset or looser stools can occur from unabsorbed fat.
Take with meals to assess tolerance.

Important Drug interactions

Blood pressure medication — forskolin may have additive effects; consult a doctor.
Diabetes medication — Salacia may lower blood sugar; monitor.
Tell your doctor about all supplements if you take medication.

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Frequently asked questions about FB3 Fusion® (Fat-Absorption Botanical Blend — Bio Actives Japan)

What is FB3 Fusion?

FB3 Fusion® is a weight-management blend from Bio Actives Japan and American Medical Holdings that combines three standardized botanicals, Coleus forskohlii, Salacia reticulata, and sesame (Sesamum indicum). Together they are designed to reduce the absorption of dietary fat and support healthy body composition.

What is FB3 Fusion used for?

FB3 Fusion is researched primarily for Weight Management and Metabolic Health. FB3 Fusion is designed to inhibit the absorption of some dietary fat, supporting weight management as part of a calorie-controlled approach.

What is the recommended dosage of FB3 Fusion?

The clinically studied dose is Per the product specification. Always follow the product label and check with a healthcare provider for personal advice.

Is FB3 Fusion safe, and does it have side effects?

For most healthy adults, FB3 Fusion is well tolerated at studied doses. Reported effects can include: Generally well-tolerated. Mild digestive upset or looser stools can occur from unabsorbed fat. It may also interact with some medications. FB3 Fusion is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does FB3 Fusion interact with any medications?

Possible interactions include: Blood pressure medication — forskolin may have additive effects; consult a doctor. Diabetes medication — Salacia may lower blood sugar; monitor. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for FB3 Fusion?

NutraSmarts rates the evidence for FB3 Fusion as Limited (2 out of 5). It is backed by 3 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(3 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Loftus HL, Astell KJ, Mathai ML, Su XQ Coleus forskohlii Extract Supplementation in Conjunction with a Hypocaloric Diet Reduces the Risk Factors of Metabolic Syndrome in Overweight and Obese Subjects: A Randomized Controlled Trial Nutrients. 2015;7(11):9508-22. doi:10.3390/nu7115483.PubMedUsed to support: Human RCT demonstrating that Coleus forskohlii extract supplementation reduced body fat percentage and improved metabolic markers in overweight subjects. Supports body-composition and fat-metabolism benefit of the Coleus forskohlii component of FB3 Fusion®; evidence is for the component, not the blend.
  2. Jeykodi S, Deshpande J, Juturu V Salacia Extract Improves Postprandial Glucose and Insulin Response: A Randomized Double-Blind, Placebo Controlled, Crossover Study in Healthy Volunteers Journal of Diabetes Research. 2016;2016:7971831. doi:10.1155/2016/7971831.PubMedUsed to support: Human double-blind crossover RCT showing Salacia extract significantly reduced postprandial glucose and insulin excursions. Supports the fat/carbohydrate absorption-reduction mechanism of the Salacia reticulata component of FB3 Fusion®; evidence is for the component, not the proprietary blend.
  3. Medagama AB Salacia reticulata (Kothala himbutu) revisited; a missed opportunity to treat diabetes and obesity? Nutrition Journal. 2015;14:21. doi:10.1186/s12937-015-0013-4.PubMedUsed to support: Review of human and animal evidence for Salacia reticulata, documenting alpha-glucosidase and alpha-amylase inhibition that reduces carbohydrate and fat absorption, supporting body-composition benefits. Evidence is for the Salacia component of FB3 Fusion®, not the blend itself.