Top 5 — Ranked by Evidence
Very Strong
Copper
Iron metabolism and anemia prevention
0.9 mg/day (RDA); 1–2 mg/day supplement; upper limit 10 mg/day; use 1 mg copper
Very Strong
Niacin
Supports Energy Metabolism
14–16 mg/day (RDA); lipid-lowering: 1,500–3,000 mg/day (extended-release niacin,
Very Strong
Omega-3 Fatty Acids
Heart Health
1–3 g/day combined EPA+DHA for general health; 2–4 g/day for triglyceride reduct
Very Strong
Pycnogenol® (French Maritime Pine Bark)
Cardiovascular health and blood pressure
50–200 mg/day; cardiovascular: 100–200 mg/day; cognitive: 100 mg/day; athletic p
Very Strong
Vitamin C
Immune System Support
75–90 mg/day (RDA); immune/antioxidant: 200–500 mg/day; upper limit 2,000 mg/day
All Hair, Skin & Nails Ingredients (45)
Very Strong
Copper
Iron metabolism and anemia prevention
0.9 mg/day (RDA); 1–2 mg/day supplement; upper limit 10 mg/day; use 1 mg copper
Very Strong
Niacin
Supports Energy Metabolism
14–16 mg/day (RDA); lipid-lowering: 1,500–3,000 mg/day (extended-release niacin,
Very Strong
Omega-3 Fatty Acids
Heart Health
1–3 g/day combined EPA+DHA for general health; 2–4 g/day for triglyceride reduct
Very Strong
Pycnogenol® (French Maritime Pine Bark)
Cardiovascular health and blood pressure
50–200 mg/day; cardiovascular: 100–200 mg/day; cognitive: 100 mg/day; athletic p
Very Strong
Vitamin C
Immune System Support
75–90 mg/day (RDA); immune/antioxidant: 200–500 mg/day; upper limit 2,000 mg/day
Very Strong
Zinc
Immune System Support
8–11 mg/day (RDA); therapeutic: 25–40 mg/day elemental zinc; upper limit 40 mg/d
Strong
CoEnzyme Q10
Heart failure mortality and cardiovascular events
100–300 mg/day ubiquinol (reduced form) or ubiquinone; heart failure: 100–300 mg
Strong
Collactive® (Marine Collagen + Hyaluronic Acid)
Wrinkle reduction and skin anti-aging
2.5–10g/day marine collagen peptides + 40–200mg/day hyaluronic acid; Collactive®
Strong
Grape Seed Extract (OPC)
Blood pressure reduction
100–400 mg/day standardized extract (≥95% OPCs); blood pressure: 150–300 mg/day
Strong
Horse Chestnut (Aesculus hippocastanum)
Chronic venous insufficiency treatment
300 mg HCSE twice daily (providing 100 mg aescin/day, 50 mg per dose); effects o
Strong
Lutein
Eye Health Benefits
6–20 mg/day; AREDS2: 10 mg/day lutein + 2 mg zeaxanthin; eye health: 10–20 mg/da
Strong
Nitrosigine® (Arginine Silicate)
Superior nitric oxide and arginine elevation
1,500 mg/day; most studies use 1,500 mg taken 30–60 minutes pre-exercise
Strong
Pantothenic Acid
Supports Energy Metabolism
5 mg/day (RDA); therapeutic: 500–1,000 mg/day for acne or lipid management
Strong
Vitamin E
Antioxidant protection
15 mg/day (RDA); therapeutic studies use 400–1,000 IU/day
Moderate
Astaxanthin
Eye Health Benefits
4–12 mg/day from Haematococcus pluvialis extract; skin: 4–6 mg/day; exercise rec
Moderate
Biotin
Supports Hair, Skin, and Nail Health
30 mcg/day (AI); hair/nail: 2,500–10,000 mcg/day (evidence weak); metabolic/neur
Moderate
Chondroitin
Joint Health and Mobility
800–1,200 mg/day chondroitin sulfate; often combined with glucosamine; 8–12 week
Moderate
Collagen
Skin Health Improvement
Take 2.5g to 10g a day of collagen peptides
Moderate
Colostrum
Immune Support
10-20g per day
Moderate
DHEA
Improved Sexual Function
25–100 mg/day; start at 25 mg and adjust based on blood DHEA-S levels; post-meno
Moderate
Echinacea
Immune System Support
300–500 mg three times daily (900–1,500 mg/day) during illness; prevention: 300
Moderate
Evening Primrose Oil (Oenothera biennis)
Eczema and atopic dermatitis improvement
3–6 g/day EPO (providing 240–480 mg GLA); eczema: 4–8 g/day; PMS: 3–4 g/day; dia
Moderate
Glucosamine
Joint Health Support
1,500 mg/day glucosamine sulfate (most studied form); split into 3×500 mg doses
Moderate
Glycine
Improved Sleep Quality
3–5 g/day for sleep quality; metabolic/detox: 5–10 g/day; collagen support: 3–5
Moderate
Hyaluronic Acid
Skin Health
80–200 mg/day oral for joint and skin benefits; skin: 120–240 mg/day; low molecu
Moderate
L-Glutamine
Gut Health Support
5–10 g/day for gut health and recovery; immune support: 20–30 g/day in clinical
Moderate
L-Lysine
Herpes simplex virus (HSV) suppression
500–3,000 mg/day; herpes suppression: 1,000–3,000 mg/day during outbreaks, 500–1
Moderate
L-Methionine
SAMe synthesis and methylation support
500–3,000 mg/day; general supplementation: 500–1,000 mg/day; therapeutic: up to
Moderate
Lycopene
Antioxidant Protection
8–21 mg/day from food or supplements; cardiovascular/prostate: 15–45 mg/day; tom
Moderate
MSM (Methylsulfonylmethane)
Joint Health and Arthritis Relief
1,000–3,000 mg/day elemental sulfur form; joint/anti-inflammatory: 1,500–3,000 m
Moderate
Natural Eggshell Membrane (NEM®)
Rapid joint pain and stiffness relief
500 mg/day NEM®; effects on joint pain and flexibility within 7–10 days in clini
Moderate
Nutroxsun® (Rosemary + Grapefruit Skin Protection)
Internal UV photoprotection
250 mg/day Nutroxsun®; take 1–2 hours before anticipated UV exposure for best ph
Moderate
PhosphatidylCholine
Gut Health
1–3 g/day (providing ~450–1,350 mg choline); take with meals
Moderate
Polypodium Leucotomos
Skin Protection Against UV Damage
Typically dosed at 240–480 mg/day
Moderate
Red Clover (Trifolium pratense)
Hot flash and menopausal symptom relief
40–160 mg/day total isoflavones; Promensil® clinical dose: 40–80 mg/day; hot fla
Moderate
Saw Palmetto
Prostate Health
160 mg twice daily (320 mg/day) standardized to 85–95% fatty acids; most studies
Moderate
Setria® Glutathione
Increased blood and tissue glutathione levels
250–500 mg/day; 250 mg shown effective for increasing blood glutathione levels
Moderate
TendoGuard® (Tendon Collagen Complex)
Tendon and ligament structural support
5–10 g/day collagen peptide complex; most tendon studies use 5–10 g/day type I c
Moderate
Zeaxanthin
Eye Health Protection
2–10 mg/day; AREDS2 formula uses 2 mg zeaxanthin + 10 mg lutein; combined lutein
Moderate
ceratiq® (Phytoceramides for Skin Hydration)
Skin hydration and moisture retention
30–200 mg/day phytoceramides; ceratiq® clinical dose per PLT Health Solutions sp
Limited
Aloe Vera (Aloe barbadensis miller)
Blood sugar regulation
Inner leaf gel: 50–300 mL/day juice; 100–300 mg/day freeze-dried gel powder; blo
Limited
Astrion® (NuLiv Science Beauty-From-Within)
Skin hydration and moisture retention
Per Astrion® product specifications; NuLiv Science beauty-from-within dosing dat
Limited
Sea Moss (Irish Moss / Gracilaria)
Dense micronutrient and mineral profile
1–4g/day dried sea moss powder or equivalent gel; no established clinical dose;
Limited
Silicon / Orthosilicic Acid
Bone mineral density support
10–40 mg/day bioavailable silicon as ch-OSA®; dietary silicon: 20–50 mg/day from
Limited
Stadice® (Joint Health Complex)
Joint comfort and mobility support
Per Stadice® product specifications; clinical dosing per Zeus Hygia product docu