Home Ingredients BiovaDerm® (Water-Soluble Eggshell Membrane for Skin — Biova)
Hair, Skin & Nails

BiovaDerm® (Water-Soluble Eggshell Membrane for Skin — Biova)

Evidence Level
Limited
0 Clinical Trials
3 Documented Benefits
2/5 Evidence Score

BiovaDerm® is a water-soluble eggshell membrane from Biova, developed for skin health. The eggshell membrane naturally contains collagen, elastin, hyaluronic acid, and glycosaminoglycans, the same building blocks that keep skin firm and hydrated, delivered in a single ingredient. Dedicated clinical evidence is still emerging.

Studied Dose Commonly around 300 to 500 mg per day.
Active Compound Water-soluble eggshell membrane providing collagen, elastin, hyaluronic acid, and glycosaminoglycans.

Benefits

Skin support

Eggshell membrane supplies collagen, elastin, and hyaluronic acid, the structural and moisture-holding components of skin, supporting firmness and hydration; dedicated trials are still emerging.

Connective-tissue building blocks

The membrane provides glycosaminoglycans used to build and maintain healthy connective tissue.

Beauty-from-within positioning

BiovaDerm is designed to support skin tone, moisture retention, and vitality from the inside.

Mechanism of action

1

Collagen and elastin supply

Eggshell membrane delivers natural collagen and elastin peptides plus the amino acids used to maintain the skin's structural matrix.

2

Hyaluronic acid and GAG support

Its hyaluronic acid and glycosaminoglycans support the skin's moisture-binding and cushioning components.

Clinical trials

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — derived from egg.
Mild digestive upset is occasionally reported.
Avoid if you have an egg allergy.

Important Drug interactions

No major drug interactions are established for this ingredient.
Tell your doctor about all supplements if you take prescription medication.
Use caution if pregnant, breastfeeding, or managing a health condition.

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Frequently asked questions about BiovaDerm® (Water-Soluble Eggshell Membrane for Skin — Biova)

What is BiovaDerm?

BiovaDerm® is a water-soluble eggshell membrane from Biova, developed for skin health. The eggshell membrane naturally contains collagen, elastin, hyaluronic acid, and glycosaminoglycans, the same building blocks that keep skin firm and hydrated, delivered in a single ingredient.

What is BiovaDerm used for?

BiovaDerm is researched primarily for Hair, Skin & Nails. Eggshell membrane supplies collagen, elastin, and hyaluronic acid, the structural and moisture-holding components of skin, supporting firmness and hydration; dedicated trials are still emerging.

What is the recommended dosage of BiovaDerm?

The clinically studied dose is Commonly around 300 to 500 mg per day. Always follow the product label and check with a healthcare provider for personal advice.

Is BiovaDerm safe, and does it have side effects?

For most healthy adults, BiovaDerm is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — derived from egg. Mild digestive upset is occasionally reported. It may also interact with some medications. BiovaDerm is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does BiovaDerm interact with any medications?

Possible interactions include: No major drug interactions are established for this ingredient. Tell your doctor about all supplements if you take prescription medication. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for BiovaDerm?

NutraSmarts rates the evidence for BiovaDerm as Limited (2 out of 5). It is backed by 3 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(3 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Ruff KJ, Winkler A, Jackson RW, DeVore DP, Ritz BW Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee: a randomized, multicenter, double-blind, placebo-controlled clinical study Clinical Rheumatology. 2009;28(8):907-14. doi:10.1007/s10067-009-1173-4.PubMedUsed to support: Multicenter RCT showing oral eggshell membrane (500 mg/day) significantly reduced knee pain and stiffness within 10 days; supports connective-tissue building-block and joint comfort claims; note: this is a joint study, not skin-specific, but demonstrates bioactivity of eggshell membrane matrix components (collagen, glycosaminoglycans) taken orally
  2. Cánovas F, Abellán-Ruíz MS, García-Muñoz AM, Luque-Rubia AJ, Victoria-Montesinos D, Pérez-Piñero S, Sánchez-Macarro M, López-Román FJ Randomised Clinical Trial to Analyse the Efficacy of Eggshell Membrane to Improve Joint Functionality in Knee Osteoarthritis Nutrients. 2022;14(11):2340. doi:10.3390/nu14112340.PubMedUsed to support: RCT confirming oral eggshell membrane improved joint functionality in knee OA; supports connective-tissue building-block benefit; shares the same collagen and glycosaminoglycan matrix relevant to BiovaDerm's skin positioning
  3. González-Rodríguez Y, La Nuez-García MA, Jiménez M, Villar-Suárez V, Casado-Santos A Comparative effects of MKARE® eggshell membrane and hydrolyzed collagen as nutricosmetics on skin biophysical properties: a randomized clinical trial Frontiers in Nutrition. 2026;12:1689701. doi:10.3389/fnut.2025.1689701.PubMedUsed to support: Randomized clinical trial demonstrating that 300 mg/day of eggshell membrane significantly improved skin firmness, flexibility, and elasticity after 57 days, outperforming hydrolyzed collagen; directly supports BiovaDerm skin-support and beauty-from-within positioning