SelectSIEVE® Apple PCQ (Apple Polyphenols)

Malus domestica
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

SelectSIEVE® Apple PCQ is a standardized apple (Malus domestica) polyphenol extract concentrated for procyanidins. Apple polyphenols are potent antioxidants, and a clinical trial found that supplementing with them supported skin condition in healthy women, the basis for the ingredient's beauty-from-within positioning.

Studied Dose Around 300 mg of apple polyphenols per day in studies.
Active Compound Standardized apple extract concentrated for procyanidins and related polyphenols.

Benefits

Skin condition

In a randomized, double-blind, placebo-controlled trial, apple polyphenol supplementation supported improvements in skin condition in healthy women.

Antioxidant defense

Apple procyanidins are strong antioxidants that help protect skin and other tissues from oxidative stress.

Beauty from within

By countering oxidative stress, apple polyphenols support skin resilience and a healthy appearance.

Mechanism of action

1

Procyanidin antioxidants

Apple procyanidins scavenge free radicals and support the skin's own antioxidant defenses against environmental stress.

2

Skin-supportive signaling

Apple polyphenols are studied for supporting skin hydration and barrier-related measures from the inside.

Clinical trials

1
Apple Polyphenols and Skin — RCT
PubMed

Randomized, double-blind, placebo-controlled trial of apple polyphenol supplements for skin conditions in healthy women. (Shoji et al. 2020, Nutrients)

Healthy women.

Apple polyphenol supplementation supported improvements in skin-condition measures versus placebo.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — adverse effects are uncommon at normal doses.
Mild digestive upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

No major drug interactions are established for this ingredient.
Tell your doctor about all supplements if you take prescription medication.
Use caution if pregnant, breastfeeding, or managing a health condition.

Frequently asked questions about SelectSIEVE® Apple PCQ (Apple Polyphenols)

What is SelectSIEVE Apple PCQ?

SelectSIEVE® Apple PCQ is a standardized apple (Malus domestica) polyphenol extract concentrated for procyanidins. Apple polyphenols are potent antioxidants, and a clinical trial found that supplementing with them supported skin condition in healthy women, the basis for the ingredient's beauty-from-within positioning.

What is SelectSIEVE Apple PCQ used for?

SelectSIEVE Apple PCQ is researched primarily for Hair, Skin & Nails and Antioxidant. In a randomized, double-blind, placebo-controlled trial, apple polyphenol supplementation supported improvements in skin condition in healthy women.

What is the recommended dosage of SelectSIEVE Apple PCQ?

The clinically studied dose is Around 300 mg of apple polyphenols per day in studies. Always follow the product label and check with a healthcare provider for personal advice.

Is SelectSIEVE Apple PCQ safe, and does it have side effects?

For most healthy adults, SelectSIEVE Apple PCQ is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — adverse effects are uncommon at normal doses. Mild digestive upset is occasionally reported. It may also interact with some medications. SelectSIEVE Apple PCQ is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does SelectSIEVE Apple PCQ interact with any medications?

Possible interactions include: No major drug interactions are established for this ingredient. Tell your doctor about all supplements if you take prescription medication. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for SelectSIEVE Apple PCQ?

NutraSmarts rates the evidence for SelectSIEVE Apple PCQ as Moderate (3 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Shoji T, Masumoto S, Moriichi N, et al. Administration of Apple Polyphenol Supplements for Skin Conditions in Healthy Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Nutrients. 2020;12(4). doi: 10.3390/nu12041071..PubMedUsed to support: RCT supporting skin benefit of apple polyphenols.