ApPhenols® (Apple Polyphenols)

ApPhenols® is an apple (Malus domestica) polyphenol ingredient concentrated for procyanidins, the antioxidant compounds richest in apple peel and unripe fruit. Apple polyphenols are studied for antioxidant, cardiometabolic, and skin support.

ApPhenols is researched primarily for Antioxidant, Cardiovascular, and Hair, Skin & Nails. Apple polyphenols (oligomeric procyanidins) are potent antioxidants that help protect cells and blood vessels from oxidative stress.

The clinically studied dose is Commonly a few hundred milligrams of apple polyphenols per day. Always follow the product label and check with a healthcare provider for personal advice.

For most healthy adults, ApPhenols is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — adverse effects are uncommon at normal doses. Mild digestive upset is occasionally reported. It may also interact with some medications. ApPhenols is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Possible interactions include: No major drug interactions are established for this ingredient. Tell your doctor about all supplements if you take prescription medication. If you take prescription medication, check with a pharmacist or doctor before using it.

NutraSmarts rates the evidence for ApPhenols as Limited (2 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.