>

Top Picks — Anti-Inflammatory

🔥 Best Anti-Inflammatory Supplements

Curcumin, Boswellia, Omega-3, and clinically-validated anti-inflammatory ingredients for chronic inflammation, joint pain, and inflammatory marker reduction.

122 ingredients reviewed Ranked by clinical evidence

← All Categories

Top 5 — Ranked by Evidence

Casperome® (Boswellia Phytosome — Indena)

Joint and exercise-induced inflammation

250-500 mg/day Casperome® (manufacturer-recommended range). The 500 mg dose was used

Anti-Inflammatory and Immune Support

250–500 mg/day EGCG standardized extract; whole green tea: 3–5 cups/day (≈240–320 mg

ThymoQuin® (Black Seed Oil — TriNutra)

Anti-inflammatory effects

Standard formulation use: 500-1,000 mg ThymoQuin® daily. Cardiometabolic protocols ty

BioTurmin® (Bioavailable Turmeric)

Anti-inflammatory support

Commonly 500 to 1000 mg of curcuminoids per day.

Anti-inflammatory and pain relief

200–400 mg/day (500–2,000 GDU) for anti-inflammatory; 400–800 mg/day with meals for d

📈 Fastest Growing Anti-Inflammatory Ingredients

Branded ingredients seeing rapid growth in formulator adoption and clinical research in 2024–2026.

Curcuwin Ultra+® (144× Bioavailable Curcumin — OmniActive)

144× Bioavailability vs Standard Curcumin

250 mg or 500 mg/day Curcuwin Ultra+ (each providing 50 mg or 100 mg curcuminoids)

CurQfen® (Curcumin-Fenugreek FenuMat — Akay Bioactives)

45.5× Free Curcuminoid Bioavailability

400-500 mg/day CurQfen (research-validated; some applications use higher)

PEA — Palmitoylethanolamide

Nerve pain: what the trials measured, and in whom

300 to 600 mg/day in the knee osteoarthritis, diabetic neuropathy and upper respiratory…

🔬 Future Anti-Inflammatory Ingredients to Watch

Lower current evidence but active research underway — these may become top picks within 2–3 years.

Casperome® (Boswellia Phytosome — Indena)

Joint and exercise-induced inflammation

250-500 mg/day (often 250 mg twice daily).

Tart Cherry Extract

Anti-inflammatory effects

Recovery: two 8 oz servings of tart cherry juice a day, or 30 mL of concentrate twice a day;…

Ginger (Zingiber officinale)

Anti-inflammatory and lipid effects

250-2,000 mg/day dried powder or extract; nausea 1-1.5 g/day; anti-inflammatory 1,000-2,000…

Recommended Anti-Inflammatory Products

Heads up: NutraSmarts may earn a commission from purchases made through these links, at no extra cost to you. We curate these picks based on the same evidence we cite throughout the page. Full disclosure.

Real products featuring the best-evidenced anti-inflammatory ingredients ranked above — chosen for clinically-studied forms and doses, third-party testing, and value. Match the supplement to your specific need.

Best foundational anti-inflammatory Amazon →

Nordic Naturals Ultimate Omega

EPA + DHA fish oil — 1280 mg per serving

Omega-3s are the most evidence-backed supplement for reducing inflammatory markers — multiple clinical trials show lower hs-CRP, IL-6, and TNF-α at 2-4 g/day EPA+DHA. Works by shifting cell membrane composition away from pro-inflammatory omega-6 eicosanoids. Nordic Naturals delivers 1280 mg EPA+DHA per serving and publishes a Certificate of Analysis for every batch.

Best botanical anti-inflammatory (Meriva®) Amazon →

Thorne Curcumin Phytosome (Meriva®)

Meriva® curcumin phytosome — 1000 mg

Meriva® pairs curcumin with phosphatidylcholine in a phytosome intended to improve absorption over plain curcumin. It is one of the better-studied curcumin forms, with trials reporting lower inflammatory markers, though most are small. It acts on COX-2 and NF-κB pathways, a different route from omega-3s, so the two are often taken together.

Best for 5-LOX pathway inflammation Amazon →

Pure Encapsulations Boswellia AKBA (5-LOXIN®)

5-LOXIN® Boswellia extract — 30% AKBA

Boswellia AKBA inhibits the 5-LOX inflammation pathway — a different mechanism than curcumin's COX-2 inhibition, which means they work synergistically rather than redundantly. 5-LOXIN® has 10x more AKBA (the most active boswellic acid) than typical Boswellia extracts. Strongest evidence for joint and arthritis-related inflammation.

Best NRF2 activator / cellular antioxidant defense Amazon →

Avmacol Extra Strength Sulforaphane

Glucoraphanin + active myrosinase enzyme

Avmacol is the #1 sulforaphane-producing supplement used in human clinical trials (Johns Hopkins and others). Sulforaphane is the most potent natural NRF2 activator known — works upstream by triggering the body's master antioxidant response (glutathione production, phase II detox enzymes). The Extra Strength version includes active myrosinase enzyme — critical because without it, the broccoli seed glucoraphanin can't convert to sulforaphane in your gut.

All Anti-Inflammatory Ingredients (122)

Casperome® (Boswellia Phytosome — Indena)

Joint and exercise-induced inflammation

250-500 mg/day Casperome® (manufacturer-recommended range). The 500 mg dose was used

Anti-Inflammatory and Immune Support

250–500 mg/day EGCG standardized extract; whole green tea: 3–5 cups/day (≈240–320 mg

ThymoQuin® (Black Seed Oil — TriNutra)

Anti-inflammatory effects

Standard formulation use: 500-1,000 mg ThymoQuin® daily. Cardiometabolic protocols ty

BioTurmin® (Bioavailable Turmeric)

Anti-inflammatory support

Commonly 500 to 1000 mg of curcuminoids per day.

Anti-inflammatory and pain relief

200–400 mg/day (500–2,000 GDU) for anti-inflammatory; 400–800 mg/day with meals for d

CurcuZen® (Curcumin Extract)

Anti-inflammatory support

Commonly 500 to 1000 mg of curcuminoids per day.

Boswellia Serrata

Anti-inflammatory and antioxidant

100 to 250 mg a day of an AKBA-enriched branded extract (5-Loxin or Aflapin) for 90 days in the osteoarthritis trials. No cited study tested boswellia for bowel conditions.

EssentiOmega® (Omega-3 Concentrate)

Anti-inflammatory support

Commonly 1 to 3 g of combined EPA and DHA per day.

Ginger (Zingiber officinale)

Anti-inflammatory and lipid effects

250–2,000 mg/day dried ginger powder or standardized extract; nausea: 1–1.5 g/day; an

PEA — Palmitoylethanolamide

Allergic and inflammatory conditions

Standard dose: 300-1,200 mg/day PEA. Most clinical trials use 600 mg twice daily (1,2

Anti-Inflammatory Effects

500-1,000 mg/day; in pooled blood pressure trials 500 mg/day or more worked while doses below 500 mg/day did nothing, and many products supply well under 500 mg.

Aronia / Chokeberry (Aronia melanocarpa)

Possible Anti-Inflammatory Effects

STANDARDIZED EXTRACT: 100-300 mg/day (25-50 mg anthocyanins) OR juice 200-300 mL/day

Curcumin/Turmeric

Anti-Inflammatory Effects

About 1,000 to 1,500 mg/day of standardized extract in divided doses; plain turmeric powder is only 2 to 5% curcuminoids, so the raw spice is not equivalent.

Serrapeptase (Serratiopeptidase)

Sinusitis and Upper Respiratory Inflammation

Products typically supply 10 to 60 mg a day, most often 10 to 30 mg, labelled as 20,000 to 80,000 enzyme units. Unit systems differ between brands, so the same milligram is not the same activity.

Ahiflower® (Buglossoides Plant Omegas — Stratum Nutrition)

GLA Content for Inflammation

1-3 g/day Ahiflower oil

Levagen+® (PEA — Palmitoylethanolamide — Gencor)

Anti-inflammatory effects

Standard dose: 300-600 mg/day Levagen+® — substantially lower than typical PEA protoc

ParActin® (Andrographis Extract — HP Ingredients)

No inflammation biomarker data in the cited studies

300 mg or 600 mg a day in the single trial; labels often suggest 100-300 mg, whose low end is below the amounts tested.

Anti-inflammatory effects

150–500 mg/day trans-resveratrol; bioavailability enhanced with piperine or liposomal

Spectra® (30-plant antioxidant blend — FutureCeuticals)

Helps maintain a healthy inflammatory response

100 mg single oral dose (capsule) in the published human crossover studies

Antioxidant and Anti-inflammatory Effects

1.5 to 3 g/day in the two primary trials (500 mg three times daily; 3,000 mg/day); endurance studies used 1 to 6 g/day, with no sign larger doses worked better.

Curcumin C3 Reduct® (Tetrahydrocurcuminoids — Sabinsa)

Anti-inflammatory support

Commonly around 150 to 600 mg per day.

AquaLOX® (Water-Soluble Boswellia AKBA — PLT Health)

Balanced inflammation

Around 100 to 250 mg of the standardized extract per day, the range used for the parent 5-LOXIN in the cited knee trial. No dose-finding study exists for the water-soluble AquaLOX form.

Cinnamon (Ceylon vs Cassia)

Anti-Inflammatory / Antioxidant

1-6 g/day cinnamon powder; 250-500 mg/day water-soluble extract (Cinnulin PF® standar

Dry N-3® (Powdered Omega-3)

Anti-inflammatory support

Commonly 1 to 3 g of combined EPA and DHA per day.

Elantria® Algal DHA (Vegan Omega-3 DHA)

Anti-inflammatory support

Commonly 1 to 3 g of combined EPA and DHA per day.

GingerWarmer® (Ginger Extract)

Anti-inflammatory and joint support

Commonly around 1 gram of ginger per day.

Ginginoll® (Ginger Extract — Akay)

Anti-inflammatory support

Commonly around 1 gram of ginger per day.

GOPO® Rosehip (Hyben Vital — Rosa canina)

GOPO galactolipid anti-inflammatory mechanism

5 g/day rosehip powder (typically split as 2.5 g twice daily). Onset of pain relief:

Limonene (D-Limonene)

Anti-inflammatory effects (in elderly individuals)

About 10 mg/kg/day (roughly 700 mg for a 70 kg adult) in the inflammation trial; 2 g/day in the breast tissue study; the 1,000 mg heartburn doses come from unpublished patent studies.

Phellodendron (Huang Bai)

Anti-inflammatory and antimicrobial effects (TCM traditional + mechanistic)

RELORA® (Phellodendron + Magnolia): 250 mg × 3/day = 750 mg/day. PHELLODENDRON ALONE

Rosehip (Rosa canina)

Effect on inflammatory markers is unproven

STANDARD: 5 g/day rosehip powder (Hyben Vital® / LitoZin®) split 2-3 doses with meals

V-Krill Omega® (Krill Omega-3)

Anti-inflammatory support

Commonly 1 to 3 g of combined EPA and DHA per day.

Anti-inflammatory effect

70 mL of 100% camu camu juice per day (about 1,050 mg vitamin C) for 7 days is the only tested dose; powder supplements at 100-500 mg per day are far smaller and untested.

Promentum® (calcium fructoborate for joint comfort, FutureCeuticals)

Helps maintain a healthy inflammatory balance

108 mg twice daily (216 mg/day); some trials used 110-220 mg/day, or 216 mg once daily

VitaCherry® Sport (whole tart cherry recovery powder — FutureCeuticals)

Promotes a healthy inflammatory and antioxidant response

Marketed at roughly 400 mg/day; class evidence used ~480 mg tart-cherry powder or ~30 mL Montmorency concentrate/day

Burdock Root (Arctium lappa)

Knee Osteoarthritis Inflammation Reduction

The only tested dose is 6 g of root per day brewed as tea for 42 days; capsules at 500-1500 mg/day and tinctures are common on labels but untested and not interchangeable with tea.

Molecular Hydrogen (H2)

Inflammation markers (one trial, not replicated)

Oral hydrogen-rich water, about 11 mg H2/day (one tablet in 250 mL, three times daily) in the 24-week metabolic syndrome trial; other cited trials used 3.5 mg/day and 7.5 mg/day.

Betalains (Beetroot Pigments)

Inflammatory markers unchanged in betalain trials

BEETROOT JUICE: 250-500 mL/day (~5-10 mmol nitrate + 30-100 mg betalains). FREEZE-DRI

Clostridium butyricum MIYAIRI 588 (CBM588 / MIYA-BM® / Butirrisan®)

Inflammatory bowel disease: no evidence cited here

20-80 mg/day MIYA-BM powder (1-4×10⁸ CFU) is the range cited for the Japanese prescription product. No adult dose is established here: the diarrhea study was in children and the cancer trials were supervised.

Curcumin C3 Complex® (Most Studied Curcumin Extract)

Anti-inflammatory pathways, shown mostly in the laboratory

500-1,000 mg/day standardized to 95% curcuminoids; all the cited trials co-administered piperine (for example 1,500 mg curcuminoids with 15 mg piperine), so account for it.

DurOmega® (Stabilized Omega-3)

Inflammation: not measured in the cited research

Commonly 1 to 3 g of combined EPA and DHA per day.

Reduced inflammatory markers

Hyperlipidemia: 1,000 mg/day × 6 weeks (the best-studied protocol). Asian clinical do

Japanese Knotweed (Polygonum cuspidatum)

Anti-inflammatory effects (small basketball player trial)

40 mg trans-resveratrol/day (200 mg of a 20% extract) in the two 6-week trials; 200 or 600 mg/day in the Gulf War Illness study. Commercial 8% extracts at 250-500 mg give 20-40 mg.

Rosmarinic Acid

Anti-inflammatory activity seen in laboratory studies

One hay fever trial used a Perilla frutescens extract supplying 50 mg or 200 mg of rosmarinic acid a day for 21 days; doses for cognition or anxiety are not established here.

Tart Cherry Extract

Anti-inflammatory effects

Recovery: two 8 oz servings of tart cherry juice a day, or 30 mL of concentrate twice a day; sleep: 30 mL of concentrate twice a day. No cited study tested a capsule dose in milligrams.

Theracurmin® (Colloidal Nanoparticle Curcumin — Theravalues)

Immune and inflammatory measures: studied, but results not detailed

150 mg a day for 12 weeks in the one trial cited here; products are commonly sold at 30-180 mg a day, doses no cited study tested.

AKBAMax® / BosPure® (Boswellia serrata Standardized to AKBA — Arjuna)

Anti-inflammatory support

Around 100 to 250 mg per day of the standardized extract on labels. No published trial has tested AKBAMax or BosPure itself, so this is a labeled amount, not a studied dose.

General Anti-Inflammatory Activity

LAKHAN/KIRBY 2014 HASHIMOTO: 9-24 mg/day × 3 mo lozenges + vit A + D3. Former Anatabl

Bifidobacterium infantis 35624 (Align® / Bifantis® / Meta Align®)

Immune and cytokine signals, mostly from studies outside IBS

PIVOTAL: 100 million CFU/day (1×10⁸) — narrow window, both 1 million and 10 billion C

BioPure DHA® (Tuna Oil Omega-3 DHA)

Lower C-reactive protein

Commonly 1 to 3 g of combined EPA and DHA per day.

CavaCurmin® (Curcumin Gamma-Cyclodextrin — Wacker)

Anti-inflammatory support

About 500 mg of the complex per day; the bioavailability study compared standardized

Curcumax (Turmeric, Ginger & Black Pepper Blend)

Inflammation — not measured in people

One capsule daily for 8 weeks (turmeric 320 mg, ginger 150 mg, black pepper 4 mg) in the only trial; authors state an effective dose has not been established.

CuroWhite® (Hydrogenated Curcuminoids — Aurea)

Antioxidant and anti-inflammatory

Around 300 to 500 mg per day.

Feverfew (Tanacetum parthenium)

Anti-inflammatory activity

50–300 mg/day dried leaf (standardized to ≥0.2% parthenolide); MIG-99: 6.25 mg three

Reduced post-surgical edema and inflammation

Digestive: 100,000–200,000 USP units per meal; Systemic anti-inflammatory: 200–400 mg

Tenzara™ (Curcumin + Boswellia FenuMat® Synergy — Akay Bioactives)

Multi-pathway anti-inflammatory mechanism

400 mg/day Tenzara once daily (Mamatha 2025 clinical trial protocol). The 24.8× free

Verilla® (Perilla Extract for Seasonal Allergy)

Anti-inflammatory support

Around 50 to 200 mg of rosmarinic acid per day.

Anti-inflammatory effects (mechanism-based)

TOPICAL CREAM: 2×/day × 3 mo. ORAL D. ALATA: 2 sachets/day = 12 mg phytosterol × 12 m

Anti-inflammatory Activity

Every human trial of isolated kaempferol used 10 mg, the highest ever 50 mg/day; commercial 50 to 200 mg capsules have never been tested, and there is no established clinical dose.

Meriva® (Curcumin Phytosome by Indena)

Absorption: About 29 Times Higher Than Unformulated Curcuminoids

1,000 mg/day Meriva (providing ~200 mg curcuminoids); some trials use 500 mg-2 g dail

Anti-inflammatory effects (preclinical, strawberry RCTs)

Human trials used whole strawberries: about 250 to 500 g fresh, or 10 to 50 g of freeze-dried powder per day; there is no established dose for purified pelargonidin itself.

Tributyrin (CoreBiome® Butyrate Prodrug)

Microbiome and inflammation effects (in vitro)

300 to 1,000 mg/day with meals is the CoreBiome label range; no dose of CoreBiome has been tested for benefit in people.

AprèsFlex® / Aflapin® (Boswellia AKBA — Laila Nutraceuticals)

Markers of inflammation in the blood

Standard dose: 100 mg twice daily (200 mg/day total) AprèsFlex®/Aflapin®. Onset of ef

Brox-25® (Bromelain)

Inflammation and swelling

Commonly 200 to 500 mg (or defined enzyme-activity units) per day.

Arnica (Arnica montana)

Post-surgical pain and swelling — formulation matters

TOPICAL (recommended): 20% tincture or 10-25% gel 2-4×/day. OTC: Arnicare®, Traumeel®

Faecalibacterium prausnitzii (Next-Generation Probiotic)

Anti-inflammatory effects in IBD

Clinical trial doses: typically 1-10 billion CFU/day in oxygen-protected formulations

Kutki (Picrorhiza kurroa)

Anti-inflammatory effects (animal and laboratory studies)

Traditional powder 0.5-1 g; the only controlled trial used 375 mg three times a day; note 3-6 g is used deliberately to cause purging, so more is not better.

Antioxidant and anti-inflammatory

DIETARY: 1-4 mg/day (walnuts, cranberries, blueberries, red wine, tea). SUPPLEMENT: 1

Myrrh (Commiphora molmol)

Anti-inflammatory Activity (Mechanistic / Preclinical)

Supplement 250-500 mg extract 2-3x/day with food; no antiparasitic dose is listed, and a suspected parasitic infection needs diagnosis and prescription treatment from a doctor.

Protease (Proteolytic Enzymes)

Chronic inflammatory and circulatory conditions

Digestive: 30,000–60,000 HUT with meals; Systemic anti-inflammatory: Wobenzym® 3 tabl

Wormwood (Artemisia absinthium)

Anti-Inflammatory and Antioxidant Effects

OMER 2007 Crohn's herbal blend: 3 × 500 mg/day × 10 wk. Krebs 2010: SedaCrohn® × 6 wk

Guggul (Commiphora mukul)

Possible Anti-Inflammatory Activity

Trials tested 50 mg guggulipid twice daily, 1,000 or 2,000 mg three times daily, and 2,160 mg a day; no dose has reliably lowered cholesterol in a Western trial.

Punarnava (Boerhavia diffusa)

Anti-inflammatory and antioxidant activity in laboratory and animal studies

Traditional amounts, not tested in people: 1 to 3 g whole plant powder, or 250 to 500 mg standardized extract two to three times a day; tea 5 to 10 g dried herb. No human trial has set a dose.

Thymocid® (Black Cumin Seed Extract — Natural Remedies)

Anti-inflammatory support

No human dose established and no trial in people has tested this ingredient; the supplier suggests 500 to 1,000 mg per day.

Xorialyc® (Olive Leaf Extract for Skin Inflammation)

Inflammatory Pathway Effects Seen in Cell Cultures

300 mg/day (research-validated dose)

Calendula (Pot Marigold)

Anti-inflammatory and antimicrobial activity (laboratory and animal models)

Topical only. Ointment or gel 2 to 5 percent applied to the skin 2 to 4 times a day. No established oral dose; no cited trial tested swallowing calendula.

Poria cocos / Wolfiporia cocos (Fu Ling / Hoelen / Tuckahoe)

Anti-swelling triterpenes in mice (animal data only)

800 mg a night of a 75 percent ethanol extract, the dose in the one sleep study (21 adults, two weeks, no placebo). Traditional use is 9 to 15 g a day of dried sclerotium; the two are not interchangeable.

Bakuchi (Bakuchiol)

Antioxidant and anti-inflammatory mechanisms

The only tested dose was a 0.5% bakuchiol cream applied to the face twice a day for 12 weeks. No oral dose has been tested here, and oral raw seed is not advisable.

Honokiol (Magnolia officinalis Bark)

Inflammation markers in cell studies only

No human trial has established a dose for purified honokiol. The studies used Relora, a magnolia plus phellodendron blend, at roughly 250 mg two to three times daily.

NaturSYN® Defense (Rye and Oyster Mushroom Blend)

Inflammatory mediators: laboratory testing only

Per the product specification.

NovaSOL® Curcumin (Liquid Micellar Curcumin — Aquanova)

Inflammation: not measured in this product's study

Often a low dose of curcuminoids per day, since absorption is much higher than standa

Boswellin® / Boswellin® Super (Standardized Boswellia serrata — Sabinsa)

Knee osteoarthritis — pain, stiffness, function

Boswellin® Super: 100-300 mg twice daily (200-600 mg/day). The Majeed 2024 dose-findi

Hytolive® (Olive Fruit Polyphenols / Hydroxytyrosol)

LDL oxidation protection (EU-authorized health claim)

5–20 mg/day hydroxytyrosol (as Hytolive®); EU health claim: ≥5 mg/day hydroxytyrosol

IBS symptom improvement

IBS (enteric-coated peppermint oil): 180-225 mg three times daily; menthol is only one component of peppermint oil, and no cited trial tested isolated menthol.

Omega-3 Fatty Acids

Triglyceride reduction

1–3 g/day combined EPA+DHA for general health; 2–4 g/day for triglyceride reduction (

5-Loxin® (Boswellia AKBA — PLT/OmniActive)

Studied in people with knee osteoarthritis

100 to 250 mg once daily, tested for 90 days only in adults already diagnosed with knee osteoarthritis, not in people without joint disease.

Upper respiratory tract infections

200-1,200 mg/day of extract standardized to >=10% andrographolides, used short term at cold onset; the clearest trial used 200 mg/day.

AstaPure® (Natural Astaxanthin — Algatech)

Antioxidant and recovery support

4 to 12 mg per day, taken with a fat-containing meal for absorption.

Diabetic peripheral neuropathy (mixed RCT results)

DIABETIC NEUROPATHY (BENDIP): 600 mg/day × 6 wk then 300 mg/day. BOND: 300 mg BID × 1

Butcher's Broom (Ruscus aculeatus)

Leg comfort and healthy vein tone (studied in venous insufficiency)

VANSCHEIDT 2002 PROTOCOL: 36-37.5 mg extract = 7-11 mg ruscogenins/day. ESCP guidelin

Curcuwin Ultra+® (144× Bioavailable Curcumin — OmniActive)

144× Bioavailability vs Standard Curcumin

250 mg or 500 mg/day Curcuwin Ultra+ (each providing 50 mg or 100 mg curcuminoids)

CurQfen® (Curcumin-Fenugreek FenuMat — Akay Bioactives)

45.5× Free Curcuminoid Bioavailability

400-500 mg/day CurQfen (research-validated; some applications use higher)

Longvida® Optimized Curcumin (Verdure Sciences)

Cognitive Function (400 mg/day)

400 mg/day Longvida (cognitive applications); 800 mg/day (joint health, exercise reco

Neem (Azadirachta indica)

Plaque and Gingivitis Reduction (RCT-Confirmed)

PINGALI 2020 T2DM: 125/250/500 mg standardized neem BID = 250-1000 mg/day × 12 wk + m

Oligopin® (French Maritime Pine Bark Extract — DRT)

Cardiometabolic support

Around 100 to 150 mg per day.

Pine Bark Extract

Cardiovascular support

Standard dose: 100-300 mg/day standardized pine bark extract (≥85% proanthocyanidins)

Pomegranate Extract

Blood pressure and arterial health

Standard cardiovascular dose: 500-1,500 mg/day pomegranate extract standardized to ≥3

Punicalagins (Pomegranate Polyphenols)

Modest blood pressure reduction

POMEGRANATE JUICE: 240 mL/day = ~318 mg punicalagins. POMx: 1000 mg/day. STANDARDIZED

Pycnogenol® (French Maritime Pine Bark)

Blood pressure — modest effect, mostly in hypertensives

50–200 mg/day; cardiovascular: 100–200 mg/day; cognitive: 100 mg/day; athletic perfor

Modest support for healthy blood pressure in people with elevated readings (meta-analysis)

BP: 60 mg/day × 4 wk hypertensive. LIPID: 200-247 mg/day (Wu 2006: 50 g/d seed). 20-H

Truebroc® (Glucoraphanin Broccoli Seed Extract — Brassica Protection Products)

What the cited human studies actually measured

30-150 mg/day (providing 4-20 mg glucoraphanin) is the usual supplement range; the cited studies used other broccoli sprout preparations, so their doses do not map onto these numbers.

Witholytin® (Olive Leaf Extract — Verdure Sciences)

Reduced fatigue and low energy

Clinical trial protocol: 500 mg twice daily (1,000 mg/day total) for 8 weeks. Mainten

Almega®PL (Microalgae EPA Omega-3 — Qualitas)

Vegan EPA omega-3

A serving providing roughly 250 mg or more of EPA per day.

Antrodia cinnamomea (Niu-Chang-Chih / Stout Camphor Fungus)

NASH 6-month RCT

NASH RCT: 3 capsules/day = 420 mg ACM × 6 months (n=28). SUBHEALTH ALT RCT: 250 mg AC

Ayuflex® (Terminalia chebula Extract — Natreon)

Joint comfort and function

250 to 500 mg per day. The clinical trial used 250 mg twice daily.

BioPerine® (Black Pepper Extract — Sabinsa)

The curcumin figure: widely quoted, not cited here

5-20 mg alongside another compound; the one positive trial used 5 mg with 120 mg CoQ10 for 21 days, while 20 mg with 250 mg resveratrol showed no change in resveratrol levels.

GliSODin® (Vegetal SOD with Gliadin — Isocell)

Antioxidant blood markers in a 19-person athlete trial

Around 250 mg per day.

HydroCurc® (Highly Bioavailable Curcumin)

Enhanced Bioavailability vs Standard Curcumin

500 mg/day; clinical trials use 250-1,000 mg/day depending on indication

Sebum regulation in oily skin (topical, industry-sponsored)

TOPICAL: 100% pure jojoba 1-2×/day, OR 5-10% in cosmetics. CLAY+JOJOBA MASK: 2-3×/wee

Mast Cell Stabilization

100-300 mg/day general use; mast cell protocols often use luteolin 100-200 mg with qu

MicrobiomeX® (Citrus Flavonoid Extract — BioActor)

Shifts gut fatty acids toward butyrate

500 mg/day (studied 250-500 mg)

Mythocondro® (Non-Animal Chondroitin Sulfate — Gnosis by Lesaffre)

Joint comfort and function in a single 60-subject pilot RCT (600 mg/day)

PIVOTAL: 600 mg/day × 12 weeks (n=60 overweight knee OA). Notably lower than typical

Oregano Oil (Origanum vulgare)

Enteric Parasite Activity (Limited Human Evidence)

600 mg/day emulsified oregano oil for enteric parasites; consumer softgels 100-300 mg/day; no dose has been established, and no study has tested dosing beyond six weeks.

Pomella® (Pomegranate Extract — Verdure Sciences)

Cardiovascular rationale (pomegranate class, not Pomella-specific trials)

Standard cardiovascular protocol: 500-1,500 mg/day Pomella® standardized extract. Mos

Thyme (Thymus vulgaris)

Acute Bronchitis Cough Reduction (Thyme-Ivy Combination)

BRONCHIPRET® THYME-IVY: 5.4 mL × 3/day × 11 d. BRONCHIPRET® TP: 1 tablet × 3/day × 11

TurmiPure Gold® (Bioavailable Turmeric — Naturex)

Higher Curcuminoid Absorption Per Milligram

Per Naturex/Givaudan TurmiPure Gold product specification

Agaricus blazei Murill (AbM / Himematsutake / Royal Sun Mushroom)

A registered trial in people receiving chemotherapy for multiple myeloma (no results cited)

No consumer dose established. The 60 mL per day figure comes from one branded liquid extract (AndoSan) given to patients about 7 weeks; those studies are not cited here.

Auricularia auricula-judae (Wood Ear / Black Jelly Mushroom)

Anticoagulant polysaccharide antithrombin-mediated

EDIBLE WOOD EAR: dietary consumption common in Asian cuisine — supports general food-

Danshen (Salvia miltiorrhiza)

Cardiovascular use in TCM and Chinese hospital practice

Oral root 9-15 g dried decoction or 1-3 g powdered; standardized 500-1,500 mg 2-3x/day; no oral dose of danshen alone has improved a cardiovascular outcome in a randomized trial.

Glycyrrhizina (Licorice Flavonoids — BGG)

The H. pylori figure is not supported here

No oral dose here is backed by a cited reference; for licorice containing glycyrrhizin, about 10 mg/day of glycyrrhizic acid is a safe intake and 400 mg/day causes adverse effects in most people.

Phellinus linteus (Meshimakobu / Sanghuang)

Immune markers in a 30-person pilot trial (trend-level results)

The Korean pilot tested 1,000 mg and 2,000 mg a day; the planned trial uses 1,000 mg a day. Human data are one small pilot, so no effective dose is established. Avoid if you have an autoimmune condition.

Pyritinol (Pyrithioxine / Encephabol)

What the dementia trial actually tested

Dementia 200 mg 3×/day (600 mg/day); these are prescription doses under medical supervision, with no established dose for self-directed use.