Home Ingredients DurOmega® (Stabilized Omega-3)
CardiovascularAnti-Inflammatory

DurOmega® (Stabilized Omega-3)

Evidence Level
Limited
1 Clinical Trial
4 Documented Benefits
2/5 Evidence Score

DurOmega® is a branded, microencapsulated form of omega-3 designed to resist oxidation and taste neutral. No published human study has tested DurOmega itself, so everything on this page comes from research on generic EPA and DHA. The main study cited here is a 2020 Cochrane review, which found that omega-3 lowers triglycerides but, at high certainty, does not reduce deaths or cardiovascular events. That review did not look at the brain or at inflammation; a separate pooled analysis of 68 generic omega-3 trials found lower blood CRP, a marker of inflammation.

Studied Dose Commonly 1 to 3 g of combined EPA and DHA per day in studies of ordinary fish, krill, or algal oil. No dose of DurOmega itself has been tested in a published human study.
Active Compound Omega-3 fatty acids EPA and DHA, from fish, krill, or algae.

Benefits

Healthy triglycerides

Omega-3 fatty acids reliably lower triglycerides, one of the best-established benefits of EPA and DHA for heart health.

Supported by Trial 1

Brain and mood: not tested by the cited research

DHA is a major structural fat in the brain, which is why omega-3s are often studied for mood and thinking skills. Neither review cited on this page measured cognition or mood, so nothing cited here supports a brain or mood benefit from this ingredient.

Supported by Trial 1

Joint symptoms: not measured in the cited research

EPA and DHA are converted into signaling molecules involved in resolving inflammation. Neither review cited on this page measured joint pain, stiffness, or other symptoms, so treat any joint benefit as background biology rather than a demonstrated benefit. Effects on blood inflammation markers are covered separately below.

Supported by Trial 1

Lower CRP and other inflammation markers in generic omega-3 trials

Tested with generic marine omega-3, not DurOmega itself. A pooled analysis of 68 randomized trials (4,601 people, doses from under 1 g to several grams a day) found CRP about 16% lower in healthy adults and 18% lower in people with chronic non-autoimmune conditions, plus lower TNF-alpha or IL-6 depending on the group. In the disease trials results varied widely and the effect faded at a BMI of 30 or more. These are blood markers, not symptoms.

Supported by Trial 1

Mechanism of action

1

Membrane incorporation

EPA and DHA are built into cell membranes throughout the body, including in the heart, brain, and eyes. That much is well documented, but a change in membrane makeup is not the same as a proven health benefit in any of those organs.

2

Eicosanoid balance

Omega-3s are converted into signaling molecules (resolvins and prostaglandins) that are involved in resolving inflammation. The resolvin pathway itself is laboratory biology; in people, the cited pooled analysis of generic omega-3 trials measured lower blood inflammation markers such as CRP, not resolvins.

Clinical trials

1
Omega-3 and cardiovascular health: Cochrane review of generic omega-3, not DurOmega
PubMed

Cochrane systematic review of omega-3 fatty acids for prevention of cardiovascular disease. (Abdelhamid et al. 2020, Cochrane Database of Systematic Reviews)

Adults in many large randomized trials. Note that this is a systematic review pooling existing studies, not a new trial, and none of those studies used DurOmega.

Omega-3 supplements lowered triglycerides. On the outcomes that matter most, the review was negative: at high certainty, omega-3 made little or no difference to death from any cause (RR 0.97) or to cardiovascular events (RR 0.96), and cardiovascular death was essentially unchanged (RR 0.92, moderate certainty). The most positive thing the review says is that omega-3 slightly reduces coronary heart disease deaths and events, at moderate to low certainty. The review did not examine cognition, mood, or inflammation.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Fishy aftertaste, burping, or mild digestive upset can occur.
Take with meals and choose a quality, oxidation-tested oil.

Important Drug interactions

Blood thinners and antiplatelet medicines (such as warfarin, clopidogrel, or daily aspirin): high doses of omega-3 may add to bleeding risk. Talk to your prescriber before combining them.
Blood pressure medication — possible mild additive effect.
Tell your doctor before surgery if taking high doses.

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Frequently asked questions about DurOmega® (Stabilized Omega-3)

What is DurOmega?

DurOmega® is a branded, microencapsulated form of omega-3 designed to resist oxidation and taste neutral. No published human study has tested DurOmega itself, so everything on this page comes from research on generic EPA and DHA.

What is DurOmega used for?

DurOmega is researched primarily for Cardiovascular and Anti-Inflammatory. Omega-3 fatty acids reliably lower triglycerides, one of the best-established benefits of EPA and DHA for heart health.

What is the recommended dosage of DurOmega?

The clinically studied dose is Commonly 1 to 3 g of combined EPA and DHA per day in studies of ordinary fish, krill, or algal oil. No dose of DurOmega itself has been tested in a published human study. Always follow the product label and check with a healthcare provider for personal advice.

Is DurOmega safe, and does it have side effects?

Side effects and cautions reported for DurOmega include: Generally well-tolerated. Fishy aftertaste, burping, or mild digestive upset can occur. It may also interact with some medications. DurOmega is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does DurOmega interact with any medications?

Possible interactions include: Blood thinners and antiplatelet medicines (such as warfarin, clopidogrel, or daily aspirin): high doses of omega-3 may add to bleeding risk. Talk to your prescriber before combining them. Blood pressure medication — possible mild additive effect. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for DurOmega?

NutraSmarts rates the evidence for DurOmega as Limited (2 out of 5). It is backed by 1 study summary and 2 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(2 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Abdelhamid AS, Brown TJ, Brainard JS, et al. Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2020;3(3):CD003177..PubMedUsed to support: Cochrane review of generic omega-3 (EPA and DHA), not of DurOmega. It supports the triglyceride benefit, but found high-certainty evidence of little or no effect on deaths or cardiovascular events, and it did not examine cognition or inflammation.
  2. Li K, Huang T, Zheng J, Wu K, Li D. Effect of marine-derived n-3 polyunsaturated fatty acids on C-reactive protein, interleukin 6 and tumor necrosis factor α: a meta-analysis. PLoS One. 2014;9(2):e88103..PubMedUsed to support: Meta-analysis of 68 randomized trials (4,601 people) of generic marine omega-3, not DurOmega. Supplementation lowered CRP (about 16% in healthy subjects and 18% in chronic non-autoimmune disease), TNF-alpha in healthy subjects and IL-6 in chronic disease. Heterogeneity was high in the disease trials, and in chronic non-autoimmune disease the CRP and TNF-alpha effects were not significant at a BMI of 30 or more.