Benefits
Seasonal allergy comfort
In a single small double-blind, placebo-controlled trial (n=29) in adults with mild seasonal allergic rhinoconjunctivitis, a perilla extract enriched for rosmarinic acid increased the responder rate for symptoms such as runny nose and itchy, watering eyes versus placebo.
Nasal and eye comfort
Perilla rosmarinic acid is studied for calming the allergic response in the nose and eyes during pollen season.
Anti-inflammatory support
Rosmarinic acid calms the inflammatory cascade that drives allergy symptoms, offering a natural complement to allergy management.
Mechanism of action
Rosmarinic acid anti-allergic action
Rosmarinic acid inhibits the inflammatory mediators and immune signaling that produce allergic symptoms, reducing nasal and eye reactions.
Antioxidant support
Perilla polyphenols provide antioxidant support that helps temper the oxidative stress of an allergic flare.
Clinical trials
Single small double-blind, placebo-controlled study (n=29) of perilla extract enriched for rosmarinic acid in mild seasonal allergic rhinoconjunctivitis. (Takano et al. 2004, Experimental Biology and Medicine)
29 adults with mild seasonal allergic rhinoconjunctivitis.
In this single small trial (n=29), the rosmarinic-acid-enriched perilla extract increased the responder rate for seasonal allergy symptoms (including itchy nose and watery eyes) versus placebo.