Home Ingredients Verilla® (Perilla Extract for Seasonal Allergy)
Respiratory HealthImmune SupportAnti-Inflammatory

Verilla® (Perilla Extract for Seasonal Allergy)

Perilla frutescens
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

Verilla® is a standardized perilla (Perilla frutescens) leaf extract enriched for rosmarinic acid, studied for easing seasonal allergy symptoms. Where perilla is also used for digestive comfort, Verilla targets the runny nose, sneezing, and itchy eyes of seasonal allergic rhinoconjunctivitis with a natural, non-drowsy approach.

Studied Dose Around 50 to 200 mg of rosmarinic acid per day.
Active Compound Standardized perilla leaf extract enriched for rosmarinic acid, a polyphenolic anti-allergic compound.

Benefits

Seasonal allergy comfort

In a human randomized study, a perilla extract enriched for rosmarinic acid reduced symptoms of seasonal allergic rhinoconjunctivitis such as runny nose and itchy, watering eyes.

Supported by Trial 1

Nasal and eye comfort

Perilla rosmarinic acid is studied for calming the allergic response in the nose and eyes during pollen season.

Supported by Trial 1

Anti-inflammatory support

Rosmarinic acid calms the inflammatory cascade that drives allergy symptoms, offering a natural complement to allergy management.

Supported by Trial 1

Mechanism of action

1

Rosmarinic acid anti-allergic action

Rosmarinic acid inhibits the inflammatory mediators and immune signaling that produce allergic symptoms, reducing nasal and eye reactions.

2

Antioxidant support

Perilla polyphenols provide antioxidant support that helps temper the oxidative stress of an allergic flare.

Clinical trials

1
Perilla Rosmarinic Acid and Allergy — Human Study
PubMed

Human study of perilla extract enriched for rosmarinic acid on seasonal allergic rhinoconjunctivitis. (Takano et al. 2004, Experimental Biology and Medicine)

Adults with seasonal allergic rhinoconjunctivitis.

The rosmarinic-acid-enriched perilla extract reduced seasonal allergy symptoms versus placebo.

Side effects and drug interactions

Common Potential side effects

GENERALLY WELL-TOLERATED — adverse effects are uncommon at normal doses.
Mild digestive upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

No major drug interactions are established for this ingredient.
May complement, not replace, prescribed allergy medication; consult your doctor.
Tell your doctor if pregnant, breastfeeding, or managing a health condition.

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Frequently asked questions about Verilla® (Perilla Extract for Seasonal Allergy)

What is Verilla® (Perilla Extract for Seasonal Allergy)?

Verilla® is a standardized perilla (Perilla frutescens) leaf extract enriched for rosmarinic acid, studied for easing seasonal allergy symptoms. Where perilla is also used for digestive comfort, Verilla targets the runny nose, sneezing, and itchy eyes of seasonal allergic rhinoconjunctivitis with a natural, non-drowsy…

What is the recommended dosage of Verilla® (Perilla Extract for Seasonal Allergy)?

The clinically studied dose for Verilla® (Perilla Extract for Seasonal Allergy) is Around 50 to 200 mg of rosmarinic acid per day.. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is Verilla® (Perilla Extract for Seasonal Allergy) used for?

Verilla® (Perilla Extract for Seasonal Allergy) is studied for seasonal allergy comfort, nasal and eye comfort, anti-inflammatory support. In a human randomized study, a perilla extract enriched for rosmarinic acid reduced symptoms of seasonal allergic rhinoconjunctivitis such as runny nose and itchy, watering eyes.

Are there side effects from taking Verilla® (Perilla Extract for Seasonal Allergy)?

Reported potential side effects may include: GENERALLY WELL-TOLERATED — adverse effects are uncommon at normal doses. Mild digestive upset is occasionally reported. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Is Verilla® (Perilla Extract for Seasonal Allergy) safe to take?

Whether Verilla® (Perilla Extract for Seasonal Allergy) is safe depends on the dose, your overall health, and any medications you take. At studied doses, reported side effects can include: GENERALLY WELL-TOLERATED — adverse effects are uncommon at normal doses. It may also interact with certain medications. Verilla® (Perilla Extract for Seasonal Allergy) is not suitable for everyone — consult a healthcare provider before use if you are pregnant or breastfeeding, have a medical condition, or take prescription medications.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Takano H, Osakabe N, Sanbongi C, et al. Extract of Perilla frutescens enriched for rosmarinic acid, a polyphenolic phytochemical, inhibits seasonal allergic rhinoconjunctivitis in humans. Exp Biol Med (Maywood). 2004;229(3):247-54..PubMedUsed to support: Human study supporting seasonal-allergy benefit of perilla rosmarinic acid.