Home Ingredients Verilla® (Perilla Extract for Seasonal Allergy)
Respiratory HealthImmune SupportAnti-Inflammatory

Verilla® (Perilla Extract for Seasonal Allergy)

Perilla frutescens
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

Verilla® is a standardized perilla (Perilla frutescens) leaf extract enriched for rosmarinic acid, studied for easing seasonal allergy symptoms. Where perilla is also used for digestive comfort, Verilla targets the runny nose, sneezing, and itchy eyes of seasonal allergic rhinoconjunctivitis with a natural, non-drowsy approach.

Studied Dose Around 50 to 200 mg of rosmarinic acid per day.
Active Compound Standardized perilla leaf extract enriched for rosmarinic acid, a polyphenolic anti-allergic compound.

Benefits

Seasonal allergy comfort

In a human randomized study, a perilla extract enriched for rosmarinic acid reduced symptoms of seasonal allergic rhinoconjunctivitis such as runny nose and itchy, watering eyes.

Supported by Trial 1

Nasal and eye comfort

Perilla rosmarinic acid is studied for calming the allergic response in the nose and eyes during pollen season.

Supported by Trial 1

Anti-inflammatory support

Rosmarinic acid calms the inflammatory cascade that drives allergy symptoms, offering a natural complement to allergy management.

Supported by Trial 1

Mechanism of action

1

Rosmarinic acid anti-allergic action

Rosmarinic acid inhibits the inflammatory mediators and immune signaling that produce allergic symptoms, reducing nasal and eye reactions.

2

Antioxidant support

Perilla polyphenols provide antioxidant support that helps temper the oxidative stress of an allergic flare.

Clinical trials

1
Perilla Rosmarinic Acid and Allergy — Human Study
PubMed

Human study of perilla extract enriched for rosmarinic acid on seasonal allergic rhinoconjunctivitis. (Takano et al. 2004, Experimental Biology and Medicine)

Adults with seasonal allergic rhinoconjunctivitis.

The rosmarinic-acid-enriched perilla extract reduced seasonal allergy symptoms versus placebo.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — adverse effects are uncommon at normal doses.
Mild digestive upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

No major drug interactions are established for this ingredient.
May complement, not replace, prescribed allergy medication; consult your doctor.
Tell your doctor if pregnant, breastfeeding, or managing a health condition.

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Frequently asked questions about Verilla® (Perilla Extract for Seasonal Allergy)

What is Verilla?

Verilla® is a standardized perilla (Perilla frutescens) leaf extract enriched for rosmarinic acid, studied for easing seasonal allergy symptoms. Where perilla is also used for digestive comfort, Verilla targets the runny nose, sneezing, and itchy eyes of seasonal allergic rhinoconjunctivitis with a natural, non-drowsy…

What is Verilla used for?

Verilla is researched primarily for Respiratory Health, Immune Support, and Anti-Inflammatory. In a human randomized study, a perilla extract enriched for rosmarinic acid reduced symptoms of seasonal allergic rhinoconjunctivitis such as runny nose and itchy, watering eyes.

What is the recommended dosage of Verilla?

The clinically studied dose is Around 50 to 200 mg of rosmarinic acid per day. Always follow the product label and check with a healthcare provider for personal advice.

Is Verilla safe, and does it have side effects?

For most healthy adults, Verilla is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — adverse effects are uncommon at normal doses. Mild digestive upset is occasionally reported. It may also interact with some medications. Verilla is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Verilla interact with any medications?

Possible interactions include: No major drug interactions are established for this ingredient. May complement, not replace, prescribed allergy medication; consult your doctor. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Verilla?

NutraSmarts rates the evidence for Verilla as Moderate (3 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Takano H, Osakabe N, Sanbongi C, et al. Extract of Perilla frutescens enriched for rosmarinic acid, a polyphenolic phytochemical, inhibits seasonal allergic rhinoconjunctivitis in humans. Exp Biol Med (Maywood). 2004;229(3):247-54..PubMedUsed to support: Human study supporting seasonal-allergy benefit of perilla rosmarinic acid.