Oligopin® (French Maritime Pine Bark Extract — DRT)

Pinus pinaster
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

Oligopin® is a French maritime pine (Pinus pinaster) bark extract from DRT, standardized for low-molecular-weight oligomeric procyanidins (OPCs). These antioxidant polyphenols are studied for supporting blood-vessel function, healthy circulation, and cardiometabolic markers.

Studied Dose Around 100 to 150 mg per day.
Active Compound French maritime pine bark extract standardized to low-molecular-weight oligomeric procyanidins (OPCs).

Benefits

Cardiometabolic support

Pine bark OPCs are studied for supporting healthy blood pressure, blood-vessel function, and cardiometabolic markers.

Antioxidant defense

The procyanidins are potent antioxidants that protect blood vessels and tissues from oxidative stress.

Circulation

By supporting nitric oxide and endothelial function, pine bark extract is used to support healthy circulation.

Mechanism of action

1

Endothelial nitric oxide

OPCs support nitric oxide production in blood-vessel linings, promoting vasodilation and healthy blood flow.

2

Antioxidant polyphenols

The low-molecular-weight procyanidins are readily absorbed and scavenge free radicals throughout the vasculature.

Clinical trials

1
Pine Bark Extract and Cardiometabolic Health — Study
PubMed

Study of supplementation with pine bark extract on cardiometabolic measures. (Mohammadi et al. 2025, BMC Complementary Medicine and Therapies)

Adults.

Pine bark extract supplementation supported cardiometabolic markers, consistent with the antioxidant and vascular actions of its procyanidins.

Side effects and drug interactions

Common Potential side effects

GENERALLY WELL-TOLERATED — adverse effects are uncommon at normal doses.
Mild digestive upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Anticoagulants and antiplatelets — possible mild additive effect; monitor.
Blood pressure medication — possible additive lowering.
Tell your doctor if you take cardiovascular medication.

Frequently asked questions about Oligopin® (French Maritime Pine Bark Extract — DRT)

What is Oligopin® (French Maritime Pine Bark Extract — DRT)?

Oligopin® is a French maritime pine (Pinus pinaster) bark extract from DRT, standardized for low-molecular-weight oligomeric procyanidins (OPCs). These antioxidant polyphenols are studied for supporting blood-vessel function, healthy circulation, and cardiometabolic markers.

What is the recommended dosage of Oligopin® (French Maritime Pine Bark Extract — DRT)?

The clinically studied dose for Oligopin® (French Maritime Pine Bark Extract — DRT) is Around 100 to 150 mg per day.. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is Oligopin® (French Maritime Pine Bark Extract — DRT) used for?

Oligopin® (French Maritime Pine Bark Extract — DRT) is studied for cardiometabolic support, antioxidant defense, circulation. Pine bark OPCs are studied for supporting healthy blood pressure, blood-vessel function, and cardiometabolic markers.

Are there side effects from taking Oligopin® (French Maritime Pine Bark Extract — DRT)?

Reported potential side effects may include: GENERALLY WELL-TOLERATED — adverse effects are uncommon at normal doses. Mild digestive upset is occasionally reported. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Is Oligopin® (French Maritime Pine Bark Extract — DRT) safe to take?

Whether Oligopin® (French Maritime Pine Bark Extract — DRT) is safe depends on the dose, your overall health, and any medications you take. At studied doses, reported side effects can include: GENERALLY WELL-TOLERATED — adverse effects are uncommon at normal doses. It may also interact with certain medications. Oligopin® (French Maritime Pine Bark Extract — DRT) is not suitable for everyone — consult a healthcare provider before use if you are pregnant or breastfeeding, have a medical condition, or take prescription medications.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Mohammadi S, Fulop T, Khalil A, et al. Does supplementation with pine bark extract improve cardiometabolic risk factors? BMC Complement Med Ther. 2025;25(1):71..PubMedUsed to support: Study supporting cardiometabolic benefit.