Home Ingredients AquaLOX® (Water-Soluble Boswellia AKBA — PLT Health)
Joint HealthAnti-Inflammatory

AquaLOX® (Water-Soluble Boswellia AKBA — PLT Health)

Boswellia serrata
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

AquaLOX® is a water-soluble form of PLT Health Solutions' clinically studied 5-LOXIN Boswellia serrata extract, enriched to about 30% AKBA (acetyl-keto-boswellic acid). It supports joint comfort and a balanced inflammatory response, in a pleasant-tasting form suited to gummies, shots, and drinks.

Studied Dose Around 100 to 250 mg of the standardized extract per day.
Active Compound Boswellia serrata extract enriched to about 30% AKBA (3-O-acetyl-11-keto-beta-boswellic acid), water-soluble.

Benefits

Joint comfort

Boswellia extracts enriched for AKBA are studied for improving joint comfort and physical function in people with knee osteoarthritis.

Supported by Trial 1

Balanced inflammation

AKBA supports a balanced inflammatory response, the basis for boswellia's joint benefits.

Supported by Trial 1

Cartilage protection

5-LOXIN has been studied for helping protect cartilage from degradation enzymes.

Supported by Trial 1

Mechanism of action

1

5-lipoxygenase inhibition

AKBA inhibits the 5-lipoxygenase (5-LOX) enzyme, reducing pro-inflammatory leukotrienes that drive joint inflammation.

2

Cartilage-enzyme support

Boswellic acids are studied for reducing the activity of enzymes (such as MMPs) that break down cartilage.

Clinical trials

1
5-LOXIN for Knee Osteoarthritis — RCT
PubMed

Double-blind, randomized, placebo-controlled study of 5-LOXIN (AKBA-enriched Boswellia serrata) for knee osteoarthritis. (Sengupta et al. 2008, Arthritis Research & Therapy)

Adults with knee osteoarthritis.

5-LOXIN improved joint pain and function versus placebo; AquaLOX is the water-soluble form of 5-LOXIN.

Side effects and drug interactions

Common Potential side effects

GENERALLY WELL-TOLERATED.
Mild digestive upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Anti-inflammatory medication — tell your doctor if combining.
May interact with drugs processed by the liver; ask your doctor.
Use caution if pregnant or breastfeeding.

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Frequently asked questions about AquaLOX® (Water-Soluble Boswellia AKBA — PLT Health)

What is AquaLOX® (Water-Soluble Boswellia AKBA — PLT Health)?

AquaLOX® is a water-soluble form of PLT Health Solutions' clinically studied 5-LOXIN Boswellia serrata extract, enriched to about 30% AKBA (acetyl-keto-boswellic acid). It supports joint comfort and a balanced inflammatory response, in a pleasant-tasting form suited to gummies, shots, and drinks.

What is the recommended dosage of AquaLOX® (Water-Soluble Boswellia AKBA — PLT Health)?

The clinically studied dose for AquaLOX® (Water-Soluble Boswellia AKBA — PLT Health) is Around 100 to 250 mg of the standardized extract per day.. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is AquaLOX® (Water-Soluble Boswellia AKBA — PLT Health) used for?

AquaLOX® (Water-Soluble Boswellia AKBA — PLT Health) is studied for joint comfort, balanced inflammation, cartilage protection. Boswellia extracts enriched for AKBA are studied for improving joint comfort and physical function in people with knee osteoarthritis.

Are there side effects from taking AquaLOX® (Water-Soluble Boswellia AKBA — PLT Health)?

Reported potential side effects may include: GENERALLY WELL-TOLERATED. Mild digestive upset is occasionally reported. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Is AquaLOX® (Water-Soluble Boswellia AKBA — PLT Health) safe to take?

Whether AquaLOX® (Water-Soluble Boswellia AKBA — PLT Health) is safe depends on the dose, your overall health, and any medications you take. At studied doses, reported side effects can include: GENERALLY WELL-TOLERATED. It may also interact with certain medications. AquaLOX® (Water-Soluble Boswellia AKBA — PLT Health) is not suitable for everyone — consult a healthcare provider before use if you are pregnant or breastfeeding, have a medical condition, or take prescription medications.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Sengupta K, Alluri KV, Satish AR, et al. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee. Arthritis Res Ther. 2008;10(4):R85..PubMedUsed to support: RCT of AKBA-enriched Boswellia serrata (5-LOXIN) for knee osteoarthritis (AquaLOX is the water-soluble 5-LOXIN).