Top Picks — Athletic Performance

💪 Best Athletic Performance Supplements

Athletic performance supplements ranked by clinical evidence — for strength, endurance, power, and recovery. Creatine, beta-alanine, caffeine, and more.

155 ingredients reviewed Ranked by clinical evidence
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Top 5 — Ranked by Evidence

📈 Fastest Growing Athletic Performance Ingredients

Branded ingredients seeing rapid growth in formulator adoption and clinical research in 2024–2026.

🔬 Future Athletic Performance Ingredients to Watch

Lower current evidence but active research underway — these may become top picks within 2–3 years.

All Athletic Performance Ingredients (155)

Very Strong
Creatine Monohydrate
Strength and high-intensity exercise performance
Standard daily: 3-5 g/day (no loading needed). Optional loading: 20 g/day × 5-7 days,
Very Strong
Provon® (Whey Protein Isolate — Glanbia)
Muscle Protein Synthesis Stimulation
20-40 g whey protein isolate per serving across published trials. 20 g provides ~2.5 g
Strong
Beta Alanine
Improved Exercise Performance
4–6 grams per day, typically taken for 2–12 weeks
Moderate
Alpha-GPC
Power output and athletic performance
AD/MCI: 400 mg × 3/day = 1200 mg/day. COGNITIVE: 300-600 mg/day. ATHLETIC: 250-600 mg
Very Strong
Caffeine
Improves Physical Performance
100–400 mg/day; performance: 3–6 mg/kg body weight 60 minutes pre-exercise; upper safe
Very Strong
Creapure® (Pharmaceutical-Grade Creatine Monohydrate)
Strength and power output
Loading: 0.3 g/kg/day for 5–7 days (typically 20 g/day split in 4 doses). Maintenance:
Very Strong
Whey Concentrate
Muscle Growth and Repair
20–40 g post-workout for muscle growth/recovery; 1.6–2 g/kg/day total protein for
Strong
Sodium Bicarbonate (Baking Soda)
High-intensity exercise performance enhancement
0.3 g/kg body weight (typically 20–25 g for 70 kg person) taken 60–90 minutes before
Very Strong
Glucose / Dextrose
Endurance exercise fuel and delayed fatigue
Oral rehydration solution 13.5 g glucose/L; sports 40-80 g/L (4-8%); endurance 30-60 g/hr (90 g/hr glucose+fructose 2:1); post-exercise 1.0-1.2 g/kg plus protein.
Strong
Sodium / Electrolyte Sodium
Endurance performance and hyponatremia prevention
1,500–2,300 mg/day dietary sodium (AI/UL); electrolyte replacement during exercise:
Strong
InnovaTea® (Natural Caffeine from Tea — NutriScience)
Exercise performance
Commonly 100 to 200 mg of caffeine per serving.
Strong
PurCaf® (Organic Caffeine from Green Coffee)
Exercise performance
Commonly 100 to 200 mg per serving; performance studies use about 3 to 6 mg per kg.
Very Strong
Iron
Oxygen transport
18 mg/day (women RDA); 27 mg/day (pregnant); 8 mg/day (men); therapeutic: 150–200 mg
Very Strong
Potassium
Potassium and normal muscle function
Adequate Intake is 2,600 mg/day for women and 3,400 mg/day for men. US supplements are capped at 99 mg per serving, so a pill cannot match what was studied; food is the realistic route.
Strong
Casein Protein
Long-term muscle and strength gains
PRE-SLEEP: 20-40 g casein 30 min before sleep (Res 2012: 40 g intrinsically labeled).
Strong
Pea Protein Isolate
Muscle Thickness and Strength Gains
20-50 g per serving; 1.4-2.0 g/kg/day total protein for resistance training. 25 g
Strong
Whey Protein Isolate
Supports muscle protein synthesis
20-40 g per serving; the cited protein targets (1.4 to 2.0 g/kg/day for exercising adults, at least 1.0 to 1.2 g/kg/day for older adults) count all food, not just supplement.
Moderate
Adenosine 5'-Triphosphate (ATP)
Athletic Performance Adjunct
400 mg/day disodium ATP (research-validated dose, primarily based on PEAK ATP studies)
Moderate
Beef Protein Isolate
Lean mass & strength (vs whey)
20-46 g/day (standard 20-30 g/dose post-workout); total protein targets of 1.6-2.0 g/kg/day are general recommendations for protein from all sources, not beef protein isolate specifically.
Moderate
Oceanix™ (Marine Phytoplankton Recovery Booster — Lonza)
Explosive strength preservation (single manufacturer-funded trial)
25 mg/day Oceanix — the small concentrated clinical dose used across multiple trials.
Strong
Ashwagandha
Testosterone and Muscle
KSM-66® root extract: 300-600 mg/day (most stress/sleep trials). Shoden®: 120-240
Strong
Creatine HCL
Strength and high-intensity exercise performance
Typical dosing: 1.5-3 g/day of creatine HCL based on marketing claims of higher
Strong
Milk Protein (MPC/MPI)
Muscle protein synthesis equivalent to whey at matched doses
MPS: 20 g = whey-equivalent. Trommelen 2020: 38 g sustained MPS 5+ hr. PRE-BED: 30-40
Limited
TestFACTOR® (Testosterone + Sexual Wellness)
Grip strength improvement
PERFORMANCE: 325 mg/day × 8 wk testosterone + sexual function. ULTRA-PERFORMANCE: 650
Strong
Wellmune (Yeast Beta-Glucan)
Athletic Recovery Support
Most Wellmune trials use 250 mg/day, taken daily for periods of 4 to 12 weeks. Some
Moderate
Betaine / TMG (Trimethylglycine)
Athletic performance — power and strength
2–6 g/day; athletic performance: 2.5 g/day (most studied dose); homocysteine
Moderate
Citrulline Malate
Resistance Training Performance
6-8 g pre-exercise (most clinical research dose); 8 g taken 60 minutes before training
Moderate
HMB (Beta-Hydroxy Beta-Methylbutyrate)
Muscle mass preservation during inactivity and aging
3 g/day in divided doses (1 g three times daily); HMB-FA: 1–3 g/day pre-workout;
Moderate
L-Leucine
Muscle protein synthesis activation
About 2 to 3 g of leucine per meal is the commonly cited threshold for muscle protein synthesis. The trials used leucine-enriched protein, so a specific free-leucine dose is not well established.
Moderate
Soy Protein
Equivalent to whey for muscle and strength gains
MUSCLE/RT: 20-40 g/day. FDA HEART CLAIM: 25 g/day. Anderson 1995 NEJM meta 38 trials:
Limited
AlphaSize® (Alpha-GPC — Chemi Nutra)
Power and exercise output
300 to 600 mg per day for cognition; about 600 mg pre-exercise in sports studies.
Strong
AstaZine® (Natural Astaxanthin from Haematococcus pluvialis — BGG)
Athletic Performance and Recovery
4-12 mg/day AstaZine (research-validated; some applications 12-24 mg)
Strong
Beetroot
Athletic endurance
About 300 to 500 mg of nitrate a day; the trials used beetroot juice, not capsules, and a 500 mg beetroot extract capsule is not the same as a studied dose.
Limited
DL-185® (Dileucine)
Superior muscle protein synthesis vs. leucine
2,000 mg (2g) once daily; absorbed 185% faster than equivalent leucine dose; clinical
Moderate
KSM-66®
Strength, Endurance, and Recovery
600 mg/day of root extract, usually 300 mg twice daily, in most trials; a 250 mg/day arm was also tested, and 675 mg/day in the oligospermia trial.
Moderate
L-Citrulline
Improved Exercise Performance
3–6 g/day L-citrulline or 6–8 g/day citrulline malate (2:1 ratio) 30–60 minutes
Moderate
Palatinose™ (Isomaltulose)
Sustained exercise fueling
25–75 g per dose in acute glycemic and exercise trials, typically replacing sucrose or
Strong
Phosphorus / Phosphate
Bone mineral density and skeletal strength
700 mg/day (RDA for adults); athletic phosphate loading: 3–4 g/day sodium phosphate
Moderate
HydroPrime® (Stabilized Glycerol)
Endurance performance and thermoregulation
2–6g glycerol (as HydroPrime®) 1–2× daily; pre-exercise hyperhydration: 1g/kg
Moderate
Taurine
Exercise Performance
1.5 to 3 g/day in the two primary trials (500 mg three times daily; 3,000 mg/day); endurance studies used 1 to 6 g/day, with no sign larger doses worked better.
Strong
Sensoril® (Ashwagandha Extract — Verdure/Natreon)
Exercise Tolerance and Recovery
125-500 mg/day Sensoril (research-validated; stress applications often 250 mg/day)
Moderate
HydroMax®
Pre-exercise hyperhydration
Pre-exercise glycerol hyperhydration: typically 1.0–1.5 g glycerol per kg body weight
Moderate
Insect Protein (Cricket / Mealworm)
Muscle protein synthesis equivalent to milk protein
MUSCLE PROTEIN SYNTHESIS: 30 g lesser mealworm = MPS equivalent to 30 g milk protein.
Moderate
Sustamine® (L-Alanyl-L-Glutamine)
Endurance and Time-to-Exhaustion
Exercise/hydration trials used roughly 1–2 g per 500 mL of fluid during activity, or
Limited
Branched-Chain Amino Acids (BCAAs)
Less Muscle Soreness After Exercise, in People Who Already Train
5–10 g/day (2:1:1 leucine:isoleucine:valine); leucine alone 2.5–3 g per meal; the cited meta-analysis reported the soreness benefit at low doses.
Limited
Lacprodan® (Branded Family of Hydrolyzed Whey and Milk Proteins)
Supports muscle protein synthesis
Class-level whey dosing in muscle protein synthesis trials is typically 20-40 g per serving (about 2-4 g leucine). No Lacprodan variant itself has been tested, so there is no studied dose for this product.
Limited
Cordyceps
Exercise performance and endurance
About 1 g/day of Cs-4 in the older-adult trial, 2 g/day in the marathon trial, 3 g/day in the cyclist trial; 1.5 g/day of Cordyceps militaris; 4 g/day of a six-mushroom blend.
Moderate
L-Arginine
Exercise Performance
3 to 6 g/day is typical in consumer products; the cited blood pressure meta-analysis pooled trials using 4 to 24 g/day. Common pre-workout doses of 6 to 10 g are not supported by any study cited here.
Moderate
RipFACTOR® (Botanical Muscle Accelerator)
Strength gains reported within 14 days in two sponsor-funded trials
Tested: 650 mg/day of LI12542F6 for 56 days, or 425 or 850 mg/day of a water-dispersible version; the two were standardized differently, so equal mass is not an equal marker dose.
Moderate
Sodium Citrate
May Support High-Intensity Performance
Ergogenic protocols use 0.3-0.5 g/kg body mass (about 0.5 g/kg most effective), taken
Limited
Terminalia Arjuna (Oxyjun®)
Cardiorespiratory endurance improvement
400 mg/day Oxyjun® in the single published, manufacturer-run heart-function trial; generic arjuna was used at 500 mg three times daily in the angina trial.
Moderate
Testofen® (Fenugreek for Male Vitality)
Resistance Training Strength and Body Composition
300-600 mg/day (libido lower; resistance training higher)
Moderate
Urolithin A
Muscle strength and endurance preservation
Standard dose: 500-1,000 mg/day urolithin A direct supplementation. Most clinical
Moderate
Zynamite® PX (Mango Leaf Extract for Sports Performance)
Peak power output improvement in single dose
140 mg Zynamite plus 140 mg quercetin as a single dose about 1 hour before exercise, per the sprint trial; no trial has tested it as an ongoing daily supplement.
Moderate
AstaPure® (Natural Astaxanthin — Algatech)
Antioxidant and recovery support
4 to 12 mg per day, taken with a fat-containing meal for absorption.
Moderate
BetaTor® (HMB Free Acid)
Muscle preservation
About 1 to 3 grams per day, often around training.
Limited
CherryPure® (Montmorency Tart Cherry — Shoreline Fruit)
Exercise recovery
Often 480 mg of cherry powder per day, or the equivalent in juice concentrate.
Limited
Epicatechin (Myostatin Inhibitor / Muscle Flavonol)
Muscle protein synthesis and grip strength
About 50 mg/day for 7 days in Gutierrez-Salmean 2014; Mafi 2019 gave daily oral epicatechin for 8 weeks alongside resistance training.
Moderate
Gynostemma pentaphyllum (Jiaogulan / Southern Ginseng)
Blood sugar: studied in people with type 2 diabetes
200 to 450 mg standardized extract daily, or 3 to 9 g a day of dried herb as tea; the diabetes trial used 6 g a day. Products and doses studied differ, so results may not transfer.
Moderate
L-Carnitine
Athletic recovery and reduced muscle damage
General supplementation: 1-3 g/day L-carnitine. Athletic recovery: 2 g/day L-carnitine
Moderate
L-Ornithine
Exercise fatigue reduction via ammonia clearance
2–6 g/day; fatigue reduction: 2 g before exercise; sleep: 400 mg before bedtime; liver
Moderate
NewCaff™ (Microencapsulated Natural Caffeine)
Exercise performance
100 to 200 mg of caffeine per serving; performance trials use about 3 to 6 mg per kg of body weight, but from studies of plain caffeine, not any study of NewCaff.
Moderate
Nitrosigine® (Arginine Silicate)
Recovery and muscle damage reduction
1,500 mg/day; most studies use 1,500 mg taken 30–60 minutes pre-exercise
Moderate
Phosphatidylserine
Exercise-induced cortisol attenuation
100-300 mg/day for cognition, with cited trials using 300 mg/day; athletic doses of 600-800 mg/day are widely quoted but not tested in any study cited here.
Moderate
PrimaVie® (Shilajit Extract — Natreon)
Muscle strength preservation during training
Clinical trial dose: 250 mg twice daily (500 mg/day total) for 90 days. CoQ10
Moderate
Pycnogenol® (French Maritime Pine Bark)
Athletic performance and recovery
50–200 mg/day; cardiovascular: 100–200 mg/day; cognitive: 100 mg/day; athletic
Moderate
ZMA® (Zinc Magnesium Aspartate — Lonza)
Athletic Recovery and Muscle Strength
30 mg zinc + 450 mg magnesium + 10.5 mg B6 (per ZMA standard formulation)
Limited
MalTor™ (Taurine + L-Malic Acid Recovery Complex)
Exercise recovery acceleration
Per MalTor™ clinical specifications; NutriScience Innovations product data; 5g MalTor™
Limited
Nitratene® (Stabilized Beet Root Nitrate)
Exercise capacity: helps in tests to exhaustion, less clear for timed performance
No dose of Nitratene itself has been tested; research used generic nitrate at about 6 to 13 mmol per day (400 to 800 mg), or 250 mL beetroot juice. A capsule is not shown equivalent to juice.
Limited
PurTea® (Organic Green Tea Caffeine — Applied Food Sciences)
Exercise performance
Commonly 100 to 200 mg of caffeine per serving.
Limited
goCOCOA® (Cocoa Flavanol Extract)
Exercise performance (mechanism only, not tested in the cited studies)
500 mg/day of cocoa flavanols including 80 mg epicatechin (COSMOS); blood pressure trials used a few hundred mg/day. No cited study tested a dose for athletic performance.
Limited
Gremin™ (Green Coffee + Curcumin BioFusion Complex)
Muscle recovery and DOMS reduction
Per Gremin™ clinical dosing; BioFusion Technology formulation per manufacturer
Moderate
Rhodiola Rosea
Physical endurance
200–600 mg/day standardized extract; taken before meals
Limited
VitaCherry® Sport (whole tart cherry recovery powder — FutureCeuticals)
Supports post-exercise muscle recovery
Marketed at roughly 400 mg/day; class evidence used ~480 mg tart-cherry powder or ~30 mL Montmorency concentrate/day
Limited
Bovine Colostrum
Exercise-induced gut permeability
10-20 g/day for 8-12 weeks in most human trials; a smaller set of trials used 0.5-1.0
Limited
Cluster Dextrin® (Highly Branched Cyclic Dextrin)
Lower perceived exertion in endurance work
15 to 70 g per session in sports products; cited human studies used 15 g during endurance exercise and 45 g during a resistance training session.
Limited
MuscleGuard™ (Vegan 4-Nutrient Sports Performance Blend — Lonza)
63% increase in composite muscle score (no exercise)
Single daily dose providing the patent-pending ratio: 1500 mg L-Carnitine + 2000 mg
Limited
Whey Protein Hydrolysate
Faster recovery of muscle force in one small trial
20-30 g of whey protein hydrolysate per serving, taken before, during, or shortly after training, with total daily intake adjusted to overall protein targets.
Limited
Black Ginger (Kaempferia parviflora / Krachaidum / Thai Ginseng)
Exercise capacity and physical performance
Human trials used 25 to 90 mg/day in elderly fitness, 180 mg/day in soccer players, 360 mg/day in adolescent athletes, and 100 mg/day in the erectile-function pilot.
Limited
cellflo6® (Gallate-Enhanced Green Tea Procyanidins — PLT Health)
Investigated for blood flow following resistance exercise
600 mg/day cellflo6 — the dose showing significant blood flow improvements in the
Limited
CordycepsPrime™ (Fermented Cordyceps sinensis Mycelium Extract)
Recovery: one 14-person study of muscle repair markers
The supplier lists 500 mg/day, but no published trial has used that dose or this material; the tested doses of about 1 to 4 g/day belong to other cordyceps products.
Limited
CordyFuel™ (Branded Cordyceps Extract)
Supports exercise endurance and oxygen utilization
Branded-specific dosing is not well defined in indexed trials. Class-level cordyceps
Limited
Creatinol-O-Phosphate (COP)
Niche pre-workout ingredient
Italian cardiology trials used variable parenteral and oral doses depending on
Limited
ElevATP®
May Support Strength Adaptations
150 mg/day in branded human studies, taken with or without other workout ingredients.
Limited
GlycerPump™
Pre-exercise hyperhydration (glycerol class)
1.2 g glycerol/kg body weight in 26 mL/kg of fluid, 30 minutes before exercise, from the generic glycerol trials; no branded GlycerPump trials exist.
Limited
GlycerSize™
Pre-exercise hyperhydration (glycerol class)
No branded GlycerSize™ RCTs. Glycerol-class hyperhydration protocols typically use
Limited
Kre-Alkalyn
Supports Muscle Strength and Power
Manufacturer-recommended use is 1.5-3 g/day without a loading phase; head-to-head
Limited
L-Isoleucine
Muscle Protein Synthesis (Adjunct to Leucine)
Typically as part of BCAA blends (2:1:1 leucine:isoleucine:valine); standalone rarely
Limited
PEAK ATP® (Disodium Adenosine Triphosphate)
Strength and lean body mass gains
400 mg/day PEAK ATP® (disodium ATP); acute: 400 mg taken 30–60 minutes pre-exercise;
Limited
PepForm® (Leucine-Rich Whey Peptides — Glanbia Nutritionals)
Higher short-term muscle protein synthesis when leucine is added to a small protein dose
About 4.2 g added leucine with a low-dose protein drink, or 20 g whey containing 3 g total leucine; these come from research drinks, not PepForm itself.
Limited
PeptiStrong® (AI-Discovered Fava Bean Peptides)
Muscle protein synthesis and recovery acceleration
2,400 mg/day PeptiStrong® (clinical dose across 3 RCTs); taken daily; muscle recovery
Limited
Senactiv®
Endurance: a 20% gain reported in one 12-person single-dose study of purified Rg1
50–100 mg/day is what products typically provide; none of the cited human studies tested this dose or this blend.
Limited
Sodium Phosphate
Proposed Oxygen Delivery Support
Loading protocols typically use about 1 g of sodium phosphate four times daily
Limited
Strengthera™
Lower body strength improvement
650 mg/day; significant results beginning at 4 weeks
Limited
Velositol® (Chromium-Driven MPS Complex - Nutrition 21)
Significantly Increases Muscle Protein Synthesis (MPS)
2 g/day Velositol with protein (research-validated)
Strong
NUTRALYS® Pea Protein (Roquette)
Muscle Protein Synthesis Comparable to Whey
20-50 g/day pea protein for muscle/sports applications; per product specification for
Limited
Amino9® (Clinically Validated EAA Blend)
Complete muscle protein synthesis stimulation
No studied dose exists for Amino9 itself; Compound Solutions defers to the finished-product label. Finished products commonly supply about 5-10 g/day.
Limited
Betalains (Beetroot Pigments)
Small endurance gains from a betalain concentrate
BEETROOT JUICE: 250-500 mL/day (~5-10 mmol nitrate + 30-100 mg betalains).
Limited
BODYBALANCE® (Bioactive Collagen Peptides — Gelita)
Body composition with exercise
About 15 grams per day, combined with resistance training.
Limited
Caffinity® (natural coffee-fruit caffeine complex — FutureCeuticals)
Supports exercise performance and endurance output
286 mg Caffinity (~200 mg natural caffeine + ~15 mg coffee-fruit polyphenols), single pre-exercise dose
Limited
Carbelac® (Whey Protein Concentrate — Carbery)
Recovery: not tested on this page
No dose of Carbelac itself has been tested. Whey protein powders are commonly used at 20 to 40 g per serving; the cited study pooled generic whey protein trials in adults 60 and over.
Limited
CarnoLife® (L-Carnitine L-Tartrate)
Exercise recovery
Commonly 1 to 2 grams of L-carnitine L-tartrate per day.
Limited
LJ100® (Tongkat Ali — HP Ingredients)
No strength or exercise-capacity evidence is cited
Standard formulation use: 100-300 mg LJ100® daily. Most clinical trials use 200
Limited
NUTRALYS® Wheat Protein (Roquette)
Plant protein for muscle support
No consumer supplement dose established for this branded ingredient; generic wheat protein trials used 30 g in young adults and 60 g in older adults, while 35 g in older adults did not.
Limited
Paraxanthine
Acute Cognitive Performance
50-200 mg as a single dose, with 100-200 mg used in the cognitive trials; every published trial tested a single dose, so there is no evidence on daily or long-term use.
Limited
Quercefit® (Quercetin Phytosome — Indena)
Run Time and Recovery in One Unblinded Athlete Registry
250 to 500 mg/day, about 100 to 200 mg quercetin, in the studies; the 1,000 mg/day senolytic figure comes from trials pairing quercetin with a prescription drug, not tested for this product.
Limited
Recoverben® (Lemon Verbena Extract — Monteloeder)
Muscle recovery
Around 400 mg per day, often taken before exercise.
Limited
Robuvit® (French Oak Wood Extract)
Athletic endurance and performance
300 mg/day Robuvit®; fatigue studies use 300 mg/day; athletic performance: 300 mg/day
Limited
Tart Cherry Extract
Post-exercise muscle recovery and reduced soreness
Recovery: two 8 oz servings of tart cherry juice a day, or 30 mL of concentrate twice a day; sleep: 30 mL of concentrate twice a day. No cited study tested a capsule dose in milligrams.
Limited
AminoZorb® (Buffered Branched-Chain Amino Acids)
Muscle support
Commonly 5 to 10 grams of BCAAs per day.
Limited
FitNox® (Plant Nitric Oxide Complex)
Exercise support (mechanistic)
Around 250 mg per day.
Limited
HydroCurc® (Highly Bioavailable Curcumin)
Exercise Recovery: Not Measured Here
500 mg/day; clinical trials use 250-1,000 mg/day depending on indication
Limited
L-Histidine
Carnosine Precursor
4 g/day for atopic dermatitis trials; 1.5–4 g/day in carnosine precursor research;
Limited
Molecular Hydrogen (H2)
Exercise: less perceived effort and lactate, no endurance gain
Oral hydrogen-rich water, about 11 mg H2/day (one tablet in 250 mL, three times daily) in the 24-week metabolic syndrome trial; other cited trials used 3.5 mg/day and 7.5 mg/day.
Limited
Prodiet® Colostrum (Bovine Colostrum — Ingredia)
Recovery support
Trials used 20 g/day, 25 g/day, or 3.2 g/day of colostrum powder. Ingredia's suggested minimum, about 0.4 to 0.5 g of powder a day, is far below the amounts used in those trials.
Limited
Testncrease® (Testosterone Support Blend)
Exercise performance and muscle support
Per Testncrease® product specifications; typically 2 capsules/day with meals; clinical
Limited
Vinitrox™ (Grape and Apple Polyphenols — Nexira)
Exercise performance support
Around 500 mg per day, often taken before exercise.
Preliminary
MyoVera™ (Chromium-Based Muscle Protein Synthesis Amplifier — Nutrition 21)
Short-term muscle protein synthesis (related ingredient, 10 people)
No studied dose exists for MyoVera; no trial of it has been published. The related amylopectin and chromium complex was tested at 2 grams with 6 grams of whey protein in ten adults.
Preliminary
Velvet Antler (Deer/Elk)
Single small trial: knee extensor strength (with caveats)
Athletic: 1.5-1.6 g/day or 560 mg/day; TCM: 0.3-1 g/day powdered; these doses were studied, not shown to work, and trials found no benefit.
Moderate
Dynagenix® (Water-Soluble Boswellia for Joint + Muscle Recovery — PLT Health)
Faster strength recovery after downhill running (60 mg a day, 10 days)
60 mg a day for 10 days in the single published Boswellia serrata recovery pilot; the 40 mg a day joint figure comes from manufacturer material, not a published trial.
Moderate
Tongkat Ali
Muscle strength and exercise recovery
Standard dose: 100-400 mg/day standardized root extract. Most clinical trials use
Limited
Mitopure® (Urolithin A — Amazentis)
Muscle strength preservation
Standard clinical dose: 500-1,000 mg/day Mitopure®. Most clinical trials use 500-1,000
Limited
Pyruvate (Calcium Pyruvate / Sodium Pyruvate)
Body fat reduction with exercise
MODERN: 5-10 g/day Ca/Na pyruvate (Kalman 1999: 6 g/day × 6 wk). STANKO 1990s: 22-53
Preliminary
Bee Pollen
Traditional use for energy and stamina
Traditional amounts, not tested doses: 1 teaspoon (about 5 g) to 1 tablespoon (15 g) daily, or capsules of 500–1,500 mg per serving. No cited trial established a dose of bee pollen.
Preliminary
Bemethyl (Bemitil / Metaprot)
Physical performance & endurance
Labelling describes 250 to 500 mg once or twice daily in courses of three to five days; no dose or schedule for athletic use has been established in any published study.
Preliminary
PureATP (Pure Adenosine 5'-Triphosphate Disodium)
Blood Flow: Rat Data and an Uncontrolled Pilot
400 mg/day ATP disodium in enteric-coated capsules, the dose used in the branded-ingredient trials. None tested an uncoated bulk powder.
Moderate
Carnipure® (L-Carnitine — Lonza)
Athletic recovery and performance
Same as generic L-carnitine: 1-3 g/day general supplementation. Specific applications:
Moderate
GeniusPure® (High-Purity Alpha-GPC)
Neuromuscular performance and power output
Healthy adults: 315 mg or 630 mg as a single dose in the GeniusPure trial, or 600 mg/day for six days. Alzheimer's trials used 1,200 mg/day, a medical rather than general supplement dose.
Limited
Ecdysterone / Turkesterone (Ecdysteroid Anabolics)
Lean muscle mass increase without hormonal side effects
Ecdysterone: 500–1,000 mg/day (12-week RCTs); Turkesterone: 500 mg/day; both: taken
Limited
Maca
Sexual Function: Studied Mostly in People With a Diagnosed Problem
1.5–3 g/day dried root powder; raw, gelatinised, yellow, red and black preparations are not interchangeable.
Limited
PeakO2® (Adaptogenic Mushroom Blend)
Better oxygen uptake (VO2 max) after three weeks
1–4g/day for ongoing use; 4g/day for clinical performance benefits (21-day loading);
Limited
Restoridyn® (Tart Cherry Extract — Anthocyte)
Faster jump recovery in one small trial of young women
The label dose is 480 mg once or twice daily, but no cited study tested 480 mg of extract; the recovery trial used 30 ml of tart cherry concentrate twice daily.
Limited
SalidroPure™ (Pure Salidroside)
Anti-fatigue and endurance
No human trial has tested the 3 to 5 mg label dose; trials of pure salidroside used 60 mg/day or 600 mg/day.
Limited
Shilajit
Muscle strength and exercise performance: one uncontrolled pilot
Standard clinical dose: 250 mg twice daily (500 mg/day total) of purified shilajit
Limited
Silk Amino Acids / Silk Fibroin Hydrolysate
Modest athletic stamina effect (small trial)
Cognitive: 200-600 mg/day of silk fibroin enzyme hydrolysate; the one stamina trial used far more, 500 mg per kilogram of body mass a day (about 35 g for a 70 kg athlete).
Limited
Yohimbe / Yohimbine (Pausinystalia yohimbe)
Body fat: one small 21 day trial in athletes
The only non-drug trial cited used 20 mg/day of yohimbine for 21 days. Yohimbe bark supplements often contain far more or less yohimbine than the label states, so the amount you take is hard to predict.
Preliminary
Eurycomanone (Tongkat Ali Quassinoid)
Muscle and exercise performance: not shown
Eurycoma longifolia extract 200 mg a day for 6 months in the only cited research; no dose of purified eurycomanone has been tested.
Preliminary
L-Valine
Building Block for Muscle Protein (Adequacy, Not Extra)
Valine on its own has not been tested for any exercise, muscle or recovery outcome; RDA 24 mg/kg/day, about 1.7 g/day for a 70 kg adult, which diet usually supplies.
Preliminary
4-Hydroxy-L-Isoleucine
Potential role in post-workout carbohydrate handling
Standalone 4-OH-Ile human data is limited; preclinical doses range 18–50 mg/kg in
Strong
Lactobacillus plantarum 299v (Lp299v / LP299V®)
Boosts non-heme iron absorption from food
PIVOTAL 10¹⁰ CFU/day (10 billion) Axling 2020 athlete 12 wk + Hoekstra 2021 pregnancy
Limited
Capsaicin / Capsicum Extract (Cayenne Pepper)
Thermogenic energy expenditure (class evidence)
2-10 mg total capsaicinoids/day (from 25-100 mg capsicum extract) in weight trials; exercise studies used a single 12 mg dose before training.
Moderate
FORTIGEL® Bioactive Collagen Peptides
Supports activity-related knee comfort
5 g per day of FORTIGEL® dissolved in water or beverage, typically taken once daily
Moderate
Metabolaid® (Hibiscus + Lemon Verbena)
AMPK activation and fat oxidation
500 mg/day Metabolaid® (325 mg lemon verbena + 175 mg hibiscus); taken before exercise
Moderate
Mycoprotein (Quorn)
Protein for muscle support
Typical dietary serving: 90-180 g cooked mycoprotein per meal (providing 11-22 g
Limited
Oxystorm® (Red Spinach Nitrate)
Nitrate for endurance & blood flow
A single 1,000 mg dose providing about 90 mg nitrate in the one Oxystorm-specific trial; generic dietary-nitrate trials used roughly 300 to 600 mg nitrate per day.
Moderate
Pomegranate Extract
Blood flow & exercise recovery
Standard cardiovascular dose: 500-1,500 mg/day pomegranate extract standardized to
Moderate
zümXR® (Targeted-Release Caffeine Technology — PLT Health)
Gradual caffeine release intended to smooth the spike and crash
Caffeine doses typically 50-300 mg per serving (matching immediate-release caffeine
Limited
AstraGin® (Astragalus and Notoginseng Saponin Extract)
Amino acid and protein absorption enhancement
50 mg twice daily (100 mg/day) in both supplementation trials; the two acute absorption tests gave 50 mg the night before and 50 mg with the test drink.
Limited
Beef Heart (Desiccated)
Richest natural food source of CoQ10
Typical supplementation: 1.5-3 g/day (2-4 capsules at 750 mg each) desiccated beef
Limited
EnduBerry™ Nu
Faster 5 km run in one trial, using a different haskap powder
The cited trial used 6 g a day of freeze-dried haskap berry powder (about 150 mg anthocyanins), but that was a different company's powder, so no dose has been established for EnduBerry Nu itself.
Limited
MitoBurn® (L-BAIBA)
White-to-brown fat conversion
250–500 mg/day; 500 mg is the full clinical dose
Limited
TendoGuard® (Tendon Collagen Complex)
Tendon and ligament structural support
No studied dose for TendoGuard, since no published trial has tested this blend; labels commonly supply 5 to 10 g/day of collagen peptides.
Preliminary
Aspartic Acid / D-Aspartic Acid (DAA)
Sperm Quality (Not Measured in Any Cited Study)
DAA: 2,500–3,000 mg/day in clinical trials; supplemental cycles typically 12 days to 4
Preliminary
Cococin® (Freeze-Dried Coconut Water — Sabinsa)
Isotonic electrolytes for sport & hydration
No oral dose of Cococin has been established or tested in a published human trial; the cited studies used a topical serum or ordinary coconut water, not Cococin powder.
Preliminary
NUTRALYS® Fava Bean Protein (Roquette)
Plant protein for muscle support
Per Roquette NUTRALYS Fava product specification; typical 20-30 g/day for protein