Home Ingredients NewCaff™ (Microencapsulated Natural Caffeine)
EnergyAthletic Performance

NewCaff™ (Microencapsulated Natural Caffeine)

Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

NewCaff™ is natural caffeine coated in a microencapsulation shell, which the manufacturer says masks caffeine's bitter taste and improves stability in a finished product. No published study has tested NewCaff itself, so the claims for the coating (taste, stability, and a smoother or slower release) are unproven. Caffeine itself is one of the most heavily studied ingredients in sports nutrition, and its effect on endurance exercise is well supported. That evidence is for caffeine in general, not for this particular coated version.

Studied Dose Products commonly supply 100 to 200 mg of caffeine per serving. Performance trials typically use about 3 to 6 mg per kg of body weight, which is roughly 200 to 400 mg for a 150 pound adult. These amounts come from studies of plain caffeine, not from any study of NewCaff.
Active Compound Caffeine, from natural green coffee or tea sources.

Benefits

Energy and alertness

Caffeine is a very widely used stimulant, and most people notice more alertness and less tiredness after a normal dose. Note that the one study cited on this page measured running endurance, not alertness, and it used ordinary caffeine rather than the NewCaff coating.

Supported by Trial 1

Exercise performance

A 2022 review that pooled results from multiple trials found caffeine improved endurance running performance and time to exhaustion compared with placebo. Those trials used ordinary caffeine. NewCaff itself has not been tested in any published trial, so this is evidence for the caffeine in the product, not for the microencapsulated form.

Supported by Trial 1

Focus

Caffeine can improve attention and reaction time, particularly when you are short on sleep. No study cited on this page measured attention or reaction time, and none tested NewCaff.

Supported by Trial 1

Mechanism of action

1

Adenosine blockade

Caffeine blocks adenosine receptors in the brain, reducing the feeling of fatigue and increasing alertness.

2

Catecholamine release

Caffeine promotes release of adrenaline, supporting energy availability and exercise output.

Clinical trials

1
Caffeine and Endurance Performance — Meta-Analysis
PubMed

Systematic review and meta-analysis pooling previously published trials of caffeine intake and endurance running performance. (Wang et al. 2022, Nutrients). This is a review of other people's studies, not a new trial, and the trials it pooled used ordinary caffeine, not NewCaff.

Adults pooled from multiple separate caffeine trials. No participant in any of these studies took NewCaff.

Caffeine improved endurance running performance and time to exhaustion compared with placebo. The review says nothing about microencapsulated caffeine, taste masking, tolerability, or how quickly a coated caffeine releases.

Side effects and drug interactions

Common Potential side effects

Can cause jitteriness, anxiety, a racing or pounding heartbeat, upset stomach, headache, and trouble sleeping.
Avoid late in the day if you are caffeine-sensitive.
Add up caffeine from coffee, tea, soda, energy drinks and other supplements. Health authorities generally suggest healthy adults stay under about 400 mg of caffeine a day. Stopping suddenly after regular use can bring on headaches and fatigue for a few days.

Important Drug interactions

Stimulant medications and other caffeine containing products: the effects add up, so use caution.
Some antibiotics (such as ciprofloxacin) and some antidepressants (such as fluvoxamine) slow down how fast your body clears caffeine, which can make a normal dose feel stronger and last much longer.
Pregnancy: recommended caffeine limits are lower, commonly around 200 mg a day, so check with your doctor before using any caffeine supplement. Breastfeeding parents are also usually advised to keep intake modest.

More Energy Ingredients

Energy
Caffeine
Caffeine, a natural stimulant found in coffee, tea, and other plants, is commonly suppleme…
Energy
Iron
Iron is an essential mineral best known for its central role in making hemoglobin, the pro…
Energy
Ferrous Sulfate
Ferrous sulfate is the most common, cheapest, and longest-established oral iron form — rec…
Energy
Riboflavin
Riboflavin (vitamin B2) is an essential water-soluble vitamin central to energy production…

Explore Other Ingredients

Cognitive
PQQ (Pyrroloquinoline Quinone)
Pyrroloquinoline quinone (PQQ) is a redox-active coenzyme that behaves as an antioxidant i…
Sleep Health
Suntheanine®
Suntheanine® is a patented, 100% pure L-isomer theanine produced via an enzymatic process…
Sleep Health
GABA
GABA (gamma-aminobutyric acid) is the body's main calming, inhibitory neurotransmitter, an…

Frequently asked questions about NewCaff™ (Microencapsulated Natural Caffeine)

What is NewCaff?

NewCaff™ is natural caffeine coated in a microencapsulation shell, which the manufacturer says masks caffeine's bitter taste and improves stability in a finished product. No published study has tested NewCaff itself, so the claims for the coating (taste, stability, and a smoother or slower release) are unproven.

What is NewCaff used for?

NewCaff is researched primarily for Energy and Athletic Performance. Caffeine is a very widely used stimulant, and most people notice more alertness and less tiredness after a normal dose. Note that the one study cited on this page measured running endurance, not alertness, and it used ordinary caffeine rath…

What is the recommended dosage of NewCaff?

The clinically studied dose is Products commonly supply 100 to 200 mg of caffeine per serving. Performance trials typically use about 3 to 6 mg per kg of body weight, which is roughly 200 to 400 mg for a 150 pound adult. Always follow the product label and check with a healthcare provider for personal advice.

Is NewCaff safe, and does it have side effects?

For most healthy adults, NewCaff is well tolerated at studied doses. Reported effects can include: Can cause jitteriness, anxiety, a racing or pounding heartbeat, upset stomach, headache, and trouble sleeping. Avoid late in the day if you are caffeine-sensitive. It may also interact with some medications. NewCaff is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does NewCaff interact with any medications?

Possible interactions include: Stimulant medications and other caffeine containing products: the effects add up, so use caution. Some antibiotics (such as ciprofloxacin) and some antidepressants (such as fluvoxamine) slow down how fast your body clears caffeine, which can make a normal dose feel stronger and l… If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for NewCaff?

NutraSmarts rates the evidence for NewCaff as Moderate (3 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Wang Z, Qiu B, Gao J, et al. Effects of Caffeine Intake on Endurance Running Performance and Time to Exhaustion: A Systematic Review and Meta-Analysis. Nutrients. 2022;15(1)..PubMedUsed to support: Meta-analysis supporting an endurance performance benefit of ordinary caffeine, the active ingredient in this branded product. It did not test the microencapsulated NewCaff form, and it did not measure alertness, focus, taste, or release rate.