Chicory Root (Cichorium intybus)

Cichorium intybus
Evidence Level
Limited
7 Clinical Trials
6 Documented Benefits
2/5 Evidence Score

Chicory root is the taproot of chicory (Cichorium intybus), a daisy-family (Asteraceae) plant. Roasted, it is brewed as a caffeine-free coffee substitute, and it is the main commercial source of inulin, a fermentable fiber. This page covers the whole root and, where labeled, inulin extracted from it; isolated chicory inulin (including the branded Oliggo-Fiber and Fibruline) has its own pages. In small placebo-controlled trials, dried whole root at 30 g a day increased stool frequency, gut bifidobacteria and fecal short-chain fatty acids, and in adults with excess weight it improved whole-body insulin sensitivity, though the main outcome fell short of significance. A roasted root drink with under 1 g of inulin a day barely changed blood sugar markers. The EU allows a bowel-function claim for 12 g a day of native chicory inulin. Gas is the most common complaint, and people allergic to daisy-family plants should avoid it.

Studied Dose Dried whole root: 15 g/day for 2 weeks, then 30 g/day for 3 to 10 weeks. Roasted root drink: 300 mL/day brewed from 10 g root (about 0.75 g inulin). Root extract: 600 to 1,800 mg/day in a safety trial. Isolated chicory inulin: 12 g/day (EU claim dose).
Active Compound Inulin-type fructans (native inulin) held in the root's cell walls of pectin, cellulose and hemicellulose, plus bitter sesquiterpene lactones (mainly lactucin, 8-deoxylactucin and lactucopicrin).

Benefits

Bowel regularity and softer stools with dried whole root

In a placebo-controlled trial in 55 adults aged 40 to 75 at raised risk of high blood sugar, dried chicory root (15 g a day, then 30 g a day for 3 weeks) raised stool frequency from 1.3 to 1.9 a day while the maltodextrin group stayed near 1.3, and stools softened more than on placebo. These were secondary outcomes; the main blood sugar outcomes did not change. The maker supplied the product.

Gut bacteria and short-chain fatty acids

In the same trial, Bifidobacterium and butyrate-producing Anaerostipes rose to about three times placebo levels, and total fecal short-chain fatty acids rose about 26% in the root group, a significant difference from placebo, all returning to baseline within 2 weeks of stopping. A 12-week trial of the same root product found similar bacterial shifts. These are gut markers, not health outcomes.

Insulin sensitivity with dried whole root over 12 weeks

In a small trial of 35 adults aged 45 to 70 with excess weight and insulin resistance, 30 g a day of dried chicory root for 10 weeks (after 2 weeks at half dose) raised whole-body insulin sensitivity on a clamp test and lowered triglycerides versus a puffed millet placebo, both secondary outcomes. The main outcome, peripheral insulin sensitivity, only trended (p = 0.085), and body weight did not change.

Blood sugar markers with a roasted root drink

In a small trial of 47 healthy Japanese adults, a roasted chicory root drink (300 mL a day, about 0.75 g inulin) for 4 weeks lowered HbA1c by 0.09 points versus 0.03 on a barley tea placebo, a very small difference, with no change in fasting glucose, insulin or blood fats. In the dried root bowel trial, fasting glucose, insulin and HOMA-IR did not differ from placebo.

Stool frequency with chicory inulin at 12 g a day (isolated fiber)

This concerns inulin extracted from the root, not the whole root. The EU authorizes the claim that chicory inulin contributes to normal bowel function by increasing stool frequency, at 12 g a day of native chicory inulin. In 44 adults with constipation, 12 g a day gave 4 stools a week versus 3 on placebo. In 12 healthy men, 20 g a day did not change stool weight or transit time.

Traditional herbal tea for mild digestive discomfort

The European Medicines Agency accepts chicory root tea (2 to 4 g of cut root in 250 mL of water once daily) as a traditional herbal medicine for mild digestive complaints such as fullness, flatulence and slow digestion, and for temporary loss of appetite. This rests on long-standing use, not on clinical trials of the tea.

Mechanism of action

1

Colonic fermentation of root inulin

Inulin from chicory root is not digested in the small intestine and is fermented by colon bacteria. In the dried root trial this raised Bifidobacterium and Anaerostipes and fecal acetate, propionate and butyrate; in lab co-cultures, these bacteria together turned the root product into butyrate.

2

Fiber kept inside intact plant cells

Dried whole root delivers its inulin still enclosed in cell walls of pectin, cellulose and hemicellulose (about 85% fiber in the tested product). The trial authors propose that this slows fermentation so it continues further along the colon, but this was not measured directly in people.

3

Bitter sesquiterpene lactones

The root contains sesquiterpene lactones, mainly lactucin, 8-deoxylactucin and lactucopicrin, which give chicory its bitter taste. The EU herbal assessment lists them among the root's constituents; their effects in people taking chicory root have not been established.

Clinical trials

1
Dried Chicory Root and Bowel Function: 7-Week Randomized Placebo-Controlled Trial
PubMed

Randomized, investigator-blinded, placebo-controlled parallel trial of bowel function, gut bacteria and glucose markers: dried chicory root cubes (WholeFiber) at 15 g/day for 2 weeks, then 30 g/day for 3 weeks, then 2 weeks off, versus maltodextrin. Publicly funded; the maker supplied the product and one author advised it. (Puhlmann et al. 2022, Gut Microbiome (Camb))

55 adults aged 40 to 75 in the Netherlands with high-normal fasting glucose plus a high diabetes risk score, or raised fasting glucose (28 root, 27 placebo analyzed; 60 enrolled).

The primary outcomes, fasting glucose, insulin and HOMA-IR, did not differ from placebo. Stool softness rose from 3.3 to 4.4 (Bristol scale), differing from placebo over time (p = 0.034), though placebo started softer; stool frequency rose from 1.3 to 1.9 a day within the root group, with placebo near 1.3. Bifidobacterium and Anaerostipes reached about three times placebo levels, and fecal short-chain fatty acids rose 26% in the root group versus a slight fall on placebo (p = 0.023).

2
Dried Chicory Root and Insulin Sensitivity: 12-Week Randomized Placebo-Controlled Trial
PubMed

Randomized, double-blind, placebo-controlled parallel trial of insulin sensitivity (clamp test), liver fat and gut bacteria: dried chicory root cubes (WholeFiber) at half dose for 2 weeks, then 30 g/day for 10 weeks, versus puffed millet (NCT04714944). Funded by an EFSD/Lilly program and Health Holland; one author is employed by the maker and another sits on its scientific board. (Omary et al. 2025, Cell Rep Med)

42 adults aged 45 to 70 with BMI 28 to 35 and insulin resistance or prediabetes were randomized; 35 were analyzed (17 root, 18 placebo).

The primary outcome, peripheral insulin sensitivity, only trended toward improvement (p = 0.085). Whole-body insulin sensitivity (p = 0.032) and non-oxidative glucose disposal (p = 0.027) rose and triglycerides fell (p = 0.049) versus placebo; liver fat only trended lower (p = 0.063). Body weight and body fat did not change, changes in defecation frequency and consistency were not significant versus placebo, and flatulence rose over time in the root group.

3
Roasted Chicory Root Drink and Blood Sugar Markers: 4-Week Randomized Trial
PubMed

Randomized, double-blind, placebo-controlled trial of blood sugar, blood fat and bowel markers: 300 mL/day of a drink brewed from 10 g of roasted chicory root (0.25 g inulin per 100 mL) versus barley tea with 10% coffee. The root came from a Japanese farm with which one author is affiliated; the authors declared no conflicts. (Nishimura et al. 2015, J Tradit Complement Med)

47 healthy Japanese adults (39 women, 8 men) aged 33 to 70.

HbA1c fell 0.09 percentage points versus 0.03 on placebo (p = 0.018), a very small difference. Fasting glucose, insulin, cholesterol, triglycerides, body weight and blood pressure did not differ between groups. Defecation rhythm scores only trended better (p = 0.051). The drink supplied about 0.75 g of inulin a day, far below the 12 g a day in the EU claim for chicory inulin.

4
Inulin-Rich Roasted Chicory Extract in Coffee Drinks: Digestive Tolerance Trials
PubMed

Two randomized, double-blind studies of digestive tolerance of a soluble roasted chicory extract added to coffee drinks: a crossover of 6-day periods (sucrose alone, or extract supplying 5.0 or 7.8 g inulin) and a 4-week parallel study (extract supplying 5.0 g inulin/day versus sucrose). The lead author is from Naturalpha, a French research company; the abstract names no funder. (Ripoll et al. 2010, Nutrition)

Healthy adults: 18 in the crossover study and 35 in the 4-week study.

At 7.8 g inulin in a morning coffee drink, overall abdominal discomfort rose slightly after 1 week (P = 0.05). At 5.0 g inulin a day for 4 weeks, flatulence, bloating, abdominal pain and stool measures did not differ from the sucrose control. At 5 g of inulin a day, digestive symptoms did not differ from the control.

5
Chicory Root Extract Capsules: Phase 1 Dose-Escalation Safety Trial (Maker-Funded)
PubMed

Phase 1, randomized, double-blind, placebo-controlled dose-escalation trial of safety and tolerability (primary) and joint symptoms (secondary) for a proprietary chicory root extract at 600, 1,200 or 1,800 mg/day for 1 month (NCT01010919). Funded by Phytomedics, the extract's developer, which employed two authors. (Olsen et al. 2010, BMC Musculoskelet Disord)

40 adults over 50 with osteoarthritis of the hip or knee, in 3 dose cohorts.

No clinically significant changes in vital signs or routine blood tests were seen. In the top dose cohort, 9 of 10 on the extract and 4 of 8 on placebo had at least 20% improvement in pain, stiffness and global scores (P = 0.06, not significant). One person on 1,800 mg/day stopped because of headache and diarrhea. This was a 1-month safety study, not proof of joint benefit.

6
Isolated Chicory Inulin 12 g/Day and Stool Frequency: Randomized Crossover Trial
PubMed

Isolated chicory inulin, not whole root. Randomized, double-blind, placebo-controlled crossover trial of bowel function: 3 x 4 g/day Orafti Inulin versus maltodextrin for 4 weeks each, with a 2-week washout (NCT02548247). Two authors were from the BENEO-Institute, part of the inulin maker. (Micka et al. 2017, Int J Food Sci Nutr)

44 otherwise healthy adults with constipation.

Median stool frequency was 4.0 a week on inulin versus 3.0 on placebo (p = 0.038), with softer stools and a trend toward higher satisfaction (p = 0.059). That is about one extra bowel movement a week.

7
Isolated Chicory Inulin 20 g/Day in Healthy Men: Randomized Crossover Trial (No Laxative Effect)
PubMed

Isolated chicory inulin, not whole root. Randomized, double-blind crossover trial of bowel function: a controlled diet with or without 20 g/day chicory inulin (chain length 2 to 60) in low-fat ice cream, 3 weeks each. (Slavin et al. 2011, Food Funct)

12 healthy men.

Stool weight, transit time, stool frequency and consistency did not change. Total anaerobic bacteria and Lactobacillus rose, and fecal ammonia and beta-glucuronidase activity fell. Flatulence increased significantly with inulin.

Side effects and drug interactions

Common Potential side effects

Gas is the most common complaint. Flatulence rose over 12 weeks on 30 g a day of dried root, and also on 20 g a day of isolated chicory inulin; a coffee drink with 7.8 g of inulin slightly raised abdominal discomfort, while 5 g a day for 4 weeks did not differ from control. The 12-week trial started at half dose for 2 weeks to help people adjust to the extra fiber.
Allergy: the EU herbal monograph lists hypersensitivity to chicory or to other plants of the daisy family (Asteraceae) as a reason not to use it; botanically, that family also includes ragweed. A case series describes oral allergy symptoms after eating chicory in 4 people with birch pollen allergy, and allergy has been reported in chicory workers.
Pregnancy, breastfeeding and children: the EU monograph does not recommend chicory root tea during pregnancy or breastfeeding because safety has not been established, and it does not recommend use under age 12 because data are lacking.
In a 1-month trial of a chicory root extract, one person on 1,800 mg a day stopped because of headache and diarrhea.

Important Drug interactions

No interactions are reported in the EU herbal monograph for chicory root.
Glucose-lowering medicines: in one small trial dried chicory root at 30 g a day improved whole-body insulin sensitivity (a secondary outcome), so a small added effect is theoretically possible; tell your clinician if you use large amounts.

Frequently asked questions about Chicory Root (Cichorium intybus)

Is chicory root coffee the same as taking inulin?

No. A drink brewed from roasted chicory root supplies far less inulin than a fiber supplement: in one trial, 300 mL a day of a roasted root drink gave about 0.75 g of inulin, while the EU bowel claim needs 12 g a day of chicory inulin. Dried whole root eaten as cubes, as in the trials, supplies much more fiber than a brewed drink.

Does chicory root contain caffeine?

No. Roasted chicory root is used as a caffeine-free coffee substitute.

Why can chicory root cause gas?

Its inulin is not digested in the small intestine and is fermented by bacteria in the colon, which produces gas. In trials, flatulence rose with 30 g a day of dried root and with 20 g a day of isolated chicory inulin, while 5 g of inulin a day in coffee drinks caused no more symptoms than a control. The 12-week trial started at half dose for 2 weeks to help people adjust.

Who should avoid chicory root?

People allergic to chicory or other daisy-family plants (Asteraceae), which the European Medicines Agency lists as a reason not to use chicory root. Some people with birch pollen allergy react to chicory in the mouth. The agency does not recommend chicory root tea during pregnancy or breastfeeding, and its use under age 12 has not been established.

What does the EU health claim for chicory inulin say?

Since 2016, foods that supply at least 12 g a day of native chicory inulin may state that chicory inulin contributes to normal bowel function by increasing stool frequency (for the first five years only the applicant, BENEO-Orafti, could use it). The claim covers inulin extracted from the root, not roasted chicory drinks, which supply far less.

What is Chicory Root?

Chicory root is the taproot of chicory (Cichorium intybus), a daisy-family (Asteraceae) plant. Roasted, it is brewed as a caffeine-free coffee substitute, and it is the main commercial source of inulin, a fermentable fiber.

What is Chicory Root used for?

Chicory Root is researched primarily for Gut Health and Metabolic Health. In a placebo-controlled trial in 55 adults aged 40 to 75 at raised risk of high blood sugar, dried chicory root (15 g a day, then 30 g a day for 3 weeks) raised stool frequency from 1.3 to 1.

What is the recommended dosage of Chicory Root?

The clinically studied dose is Dried whole root: 15 g/day for 2 weeks, then 30 g/day for 3 to 10 weeks. Roasted root drink: 300 mL/day brewed from 10 g root (about 0.75 g inulin). Root extract: 600 to 1,800 mg/day in a safety trial. Isolated chicory inulin: 12 g/day (EU claim dose). Always follow the product label and check with a healthcare provider for personal advice.

Is Chicory Root safe, and does it have side effects?

Side effects and cautions reported for Chicory Root include: Gas is the most common complaint. Flatulence rose over 12 weeks on 30 g a day of dried root, and also on 20 g a day of isolated chicory inulin; a coffee drink with 7.8 g of inulin slightly raised abdominal discomfort, while 5 g a day for 4 weeks did not differ from control. It may also interact with some medications. Chicory Root is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Chicory Root interact with any medications?

Possible interactions include: No interactions are reported in the EU herbal monograph for chicory root. Glucose-lowering medicines: in one small trial dried chicory root at 30 g a day improved whole-body insulin sensitivity (a secondary outcome), so a small added effect is theoretically possible; tell your cl… If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Chicory Root?

NutraSmarts rates the evidence for Chicory Root as Limited (2 out of 5). It is backed by 7 study summaries and 14 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(14 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Puhlmann ML, Jokela R, van Dongen KCW, Bui TPN, van Hangelbroek RWJ, Smidt H, de Vos WM, Feskens EJM. Dried chicory root improves bowel function, benefits intestinal microbial trophic chains and increases faecal and circulating short chain fatty acids in subjects at risk for type 2 diabetes. Gut Microbiome (Camb). 2022;3:e4. doi: 10.1017/gmb.2022.4.PubMedUsed to support: Randomized, investigator-blinded, placebo-controlled trial in 55 Dutch adults at risk of type 2 diabetes: dried whole chicory root (15 then 30 g/day) increased stool frequency and softness, Bifidobacterium and Anaerostipes, and fecal short-chain fatty acids versus maltodextrin, all reversibly. The primary glucose outcomes (fasting glucose, insulin, HOMA-IR) did not differ from placebo. Publicly funded; the maker supplied the product and one author advised it.
  2. Omary L, Canfora EE, Puhlmann ML, Gavriilidou A, Rijnaarts I, Holst JJ, Op den Kamp-Bruls YMH, de Vos WM, Blaak EE. Intrinsic chicory root fibers modulate colonic microbial butyrate-producing pathways and improve insulin sensitivity in individuals with obesity. Cell Rep Med. 2025;6(7):102237. doi: 10.1016/j.xcrm.2025.102237.PubMedUsed to support: Randomized, double-blind, placebo-controlled 12-week trial (35 analyzed) in adults with BMI 28 to 35 at risk of type 2 diabetes: 30 g/day dried chicory root raised whole-body insulin sensitivity (p = 0.032) and lowered triglycerides (p = 0.049) versus puffed millet, while the primary outcome, peripheral insulin sensitivity, only trended (p = 0.085). No change in body weight. One author is employed by the maker, which supplied the product, and another sits on its scientific board; funded by the EFSD/Lilly European Diabetes Research Program and TKI/Health Holland.
  3. Nishimura M, Ohkawara T, Kanayama T, Kitagawa K, Nishimura H, Nishihira J. Effects of the extract from roasted chicory (Cichorium intybus L.) root containing inulin-type fructans on blood glucose, lipid metabolism, and fecal properties. J Tradit Complement Med. 2015;5(3):161-7. doi: 10.1016/j.jtcme.2014.11.016.PubMedUsed to support: Randomized, double-blind, placebo-controlled 4-week trial in 47 healthy Japanese adults: a roasted chicory root drink (300 mL/day, about 0.75 g inulin) lowered HbA1c slightly more than a barley tea placebo (0.09 versus 0.03 points, p = 0.018), with no between-group change in fasting glucose, insulin, lipids or body weight; bowel scores only trended better.
  4. Ripoll C, Flourié B, Megnien S, Hermand O, Janssens M. Gastrointestinal tolerance to an inulin-rich soluble roasted chicory extract after consumption in healthy subjects. Nutrition. 2010;26(7-8):799-803. doi: 10.1016/j.nut.2009.07.013.PubMedUsed to support: Two randomized double-blind studies in healthy adults: a coffee drink with roasted chicory extract supplying 7.8 g inulin slightly raised overall abdominal discomfort after 1 week (P = 0.05), while 5.0 g inulin a day for 4 weeks caused no more digestive symptoms than a sucrose control.
  5. Olsen NJ, Branch VK, Jonnala G, Seskar M, Cooper M. Phase 1, placebo-controlled, dose escalation trial of chicory root extract in patients with osteoarthritis of the hip or knee. BMC Musculoskelet Disord. 2010;11:156. doi: 10.1186/1471-2474-11-156.PubMedUsed to support: Phase 1 randomized double-blind dose-escalation trial in 40 adults with hip or knee osteoarthritis: a proprietary chicory root extract at 600 to 1,800 mg/day for 1 month raised no safety signals in vital signs or blood tests; the responder difference in the top dose cohort (9 of 10 versus 4 of 8) was not significant (P = 0.06). One participant stopped for headache and diarrhea. Funded by the extract's developer, which employed two authors.
  6. Micka A, Siepelmeyer A, Holz A, Theis S, Schön C. Effect of consumption of chicory inulin on bowel function in healthy subjects with constipation: a randomized, double-blind, placebo-controlled trial. Int J Food Sci Nutr. 2017;68(1):82-89. doi: 10.1080/09637486.2016.1212819.PubMedUsed to support: Crossover trial in 44 adults with constipation testing isolated chicory inulin (Orafti Inulin, 12 g/day) for 4 weeks: median 4.0 stools a week versus 3.0 on maltodextrin (p = 0.038), with softer stools. Two authors were from the BENEO-Institute.
  7. Slavin J, Feirtag J. Chicory inulin does not increase stool weight or speed up intestinal transit time in healthy male subjects. Food Funct. 2011;2(1):72-7. doi: 10.1039/c0fo00101e.PubMedUsed to support: Randomized double-blind crossover in 12 healthy men on a controlled diet: 20 g/day isolated chicory inulin for 3 weeks did not change stool weight, transit time, frequency or consistency, raised total anaerobes and Lactobacillus, lowered fecal ammonia, and increased flatulence.
  8. Nagy DU, Sándor-Bajusz KA, Bódy B, Decsi T, Van Harsselaar J, Theis S, Lohner S. Effect of chicory-derived inulin-type fructans on abundance of Bifidobacterium and on bowel function: a systematic review with meta-analyses. Crit Rev Food Sci Nutr. 2023;63(33):12018-12035. doi: 10.1080/10408398.2022.2098246.PubMedUsed to support: Meta-analyses of randomized trials of chicory-derived inulin-type fructans at 3 to 20 g/day: Bifidobacterium abundance rose (50 studies, 2,525 participants, standardized mean difference 0.83), except in people with gastrointestinal disorders, and bowel function improved in healthy people. Two of the seven authors were from the BENEO-Institute.
  9. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific Opinion on the substantiation of a health claim related to “native chicory inulin” and maintenance of normal defecation by increasing stool frequency pursuant to Article 13.5 of Regulation (EC) No 1924/2006. EFSA Journal. 2015;13(1):3951. doi: 10.2903/j.efsa.2015.3951. Not PubMed-indexed..SourceUsed to support: Not PubMed-indexed; read on the EFSA Journal site. Opinion on an application by BENEO-Orafti: six studies in 86 subjects showed that at least 12 g/day of native chicory inulin (a non-fractionated chicory extract with mean chain length of 9 or more) increases stool frequency, and the panel concluded that a cause and effect relationship was established.
  10. European Commission. Commission Regulation (EU) 2015/2314 of 7 December 2015 authorising a health claim made on foods, other than those referring to the reduction of disease risk and to children's development and health and amending Regulation (EU) No 432/2012. Official Journal of the European Union. 2015;L 328, p. 46, 12 December 2015. Not PubMed-indexed..SourceUsed to support: Not PubMed-indexed; read on EUR-Lex. Authorizes the claim 'Chicory inulin contributes to normal bowel function by increasing stool frequency' for foods supplying at least 12 g/day of native chicory inulin, with consumers told the effect is obtained at 12 g/day; use was restricted to BENEO-Orafti for five years from 1 January 2016.
  11. European Medicines Agency, Committee on Herbal Medicinal Products (HMPC). Community herbal monograph on Cichorium intybus L., radix (EMA/HMPC/121816/2010). European Medicines Agency. 2013;Final, adopted 15 January 2013. Not PubMed-indexed..SourceUsed to support: Not PubMed-indexed; read on the EMA website. Traditional herbal medicinal product (tea of 2 to 4 g cut root once daily) for mild digestive complaints and temporary loss of appetite, based exclusively on long-standing use. Contraindicated in hypersensitivity to chicory or other Asteraceae plants; not recommended in pregnancy and lactation, and use under age 12 not established; no interactions or undesirable effects known.
  12. European Medicines Agency, Committee on Herbal Medicinal Products (HMPC). Assessment report on Cichorium intybus L., radix (EMA/HMPC/113041/2010). European Medicines Agency. 2013;Final, 15 January 2013. Not PubMed-indexed..SourceUsed to support: Not PubMed-indexed; read on the EMA website. Describes chicory as a member of the Asteraceae whose roots are roasted and used as a coffee substitute, names lactucin, 8-deoxylactucin and lactucopicrin as the main bitter sesquiterpene lactones, notes that reported chicory allergy cases were mainly occupational, and adds the Asteraceae contraindication because the family is a known source of allergy.
  13. Cadot P, Kochuyt AM, van Ree R, Ceuppens JL. Oral allergy syndrome to chicory associated with birch pollen allergy. Int Arch Allergy Immunol. 2003;131(1):19-24. doi: 10.1159/000070430.PubMedUsed to support: Report of 4 patients with birch pollen allergy and oral allergy syndrome to chicory, with laboratory evidence of chicory and birch pollen cross-reactivity. A case series, not a trial.
  14. Schumacher E, Vigh E, Molnár V, Kenyeres P, Fehér G, Késmárky G, Tóth K, Garai J. Thrombosis preventive potential of chicory coffee consumption: a clinical study. Phytother Res. 2011;25(5):744-8. doi: 10.1002/ptr.3481.PubMedUsed to support: One-week study in 27 healthy volunteers drinking 300 mL/day of caffeine-free chicory coffee: the abstract reports lower whole blood and plasma viscosity and serum MIF and variable platelet effects after 1 week, and describes no control group. Laboratory markers only.