Benefits
Stool frequency with chicory inulin from other makers at 12 g a day
Oliggo-Fiber itself has not been tested for bowel function. In a placebo-controlled crossover trial of another maker's chicory inulin in 44 adults with constipation, 12 g a day for 4 weeks gave a median of 4 stools a week versus 3 on maltodextrin, with softer stools. Two authors worked for that inulin maker. The EU bowel claim for native chicory inulin also uses 12 g a day; no source shows Oliggo-Fiber meets its definition.
Gut bifidobacteria with chicory inulin in snack bars (other makers)
In two placebo-controlled crossover trials in 50 adults who ate little fiber, snack bars with 7 g a day of chicory inulin-type fructans raised fecal Bifidobacterium from about 5% to 19% of bacteria versus control bars; at 3 g a day the rise showed only on a targeted test. Fecal short-chain fatty acids did not differ. The fiber's maker is not named; a food company funded the work.
Colon fermentation markers after a single 24 g dose of Oliggo-Fiber
In two small randomized crossover studies, 24 g of Oliggo-Fiber Instant Inulin taken with 75 g glucose raised breath hydrogen (and methane in the smaller study), and in the larger study blood short-chain fatty acids 4 to 6 hours later, compared with glucose alone. These are short-term signs that colon bacteria ferment it, not a measured health effect.
Appetite hormones and next-meal blood sugar after one dose of Oliggo-Fiber
In 25 adults, 24 g of Oliggo-Fiber Instant Inulin with glucose did not change GLP-1 or PYY, hormones linked to fullness, or the glucose and insulin response to a lunch 4 hours later, compared with glucose alone. The hunger hormone ghrelin was lower at 6 hours, but not across the 4 to 6 hour period.
Mechanism of action
Fermentation by colon bacteria
Inulin passes the small intestine undigested and is fermented by colon bacteria into gases and short-chain fatty acids. Within hours of a 24 g dose of Oliggo-Fiber Instant Inulin, breath hydrogen rose in both published studies, breath methane in the smaller one, and serum short-chain fatty acids in the larger one.
Selective growth of bifidobacteria
In placebo-controlled trials of chicory inulin from other makers, fecal Bifidobacterium rose with 7 g a day in snack bars and with 15 g a day in older adults, which suggests these bacteria are among those that use the fiber.
Water and gas in the lower gut
Fructans, the carbohydrate class that includes inulin, are among the rapidly fermentable carbohydrates (FODMAPs) that bring fermentable material and water to the end of the small intestine and the colon, which can cause distension, gas and bloating in sensitive people.
Clinical trials
Randomized, single-blind crossover study over 4 hours: 75 g glucose with or without 24 g Oliggo-Fiber Instant Inulin (Cargill) in 300 mL water, one test day each. Main outcomes were colon fermentation markers (breath hydrogen and methane, and serum short-chain fatty acids, called fermentation acids in this card). Funded by the Canadian Institutes of Health Research; the authors declared no conflicts. (Fernandes et al. 2011, Eur J Clin Nutr)
18 adults (11 women, 7 men) with a BMI of 20 to 35: 9 with normal and 9 with high fasting insulin.
Breath hydrogen and methane rose more after inulin than after glucose alone, but the rise in serum fermentation acids was not statistically significant. Free fatty acids were lower 4 hours after inulin than after glucose (0.310 versus 0.432 mEq/L, P = 0.008) in both insulin groups. No adverse reactions were reported.
One randomized crossover trial reported in two papers: 75 g glucose alone, or with 24 g Oliggo-Fiber Instant Inulin (Cargill) or 28 g resistant starch, in 300 mL water on three test days, with a standard lunch 4 hours later (NCT02562014); described as single-blind. Fermentation acids in this card means serum short-chain fatty acids. Funded by the Canadian Institutes of Health Research; the authors declared no conflicts. (Rahat-Rozenbloom et al. 2017, Eur J Clin Nutr)
25 adults aged 18 to 65: 12 lean and 13 with overweight or obesity.
Compared with glucose alone, inulin raised serum fermentation acids (P < 0.001) but did not change free fatty acids, the glucose and insulin response to lunch, or GLP-1 and PYY. Blood glucose over the first 2 hours was higher after inulin. Ghrelin was lower 6 hours after inulin (P < 0.05) but not across the 4 to 6 hour period. Lean and overweight participants responded alike.