Home Ingredients VitaCholine® (Choline Bitartrate — Balchem)
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VitaCholine® (Choline Bitartrate — Balchem)

Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

VitaCholine® is a high-quality choline L-bitartrate from Balchem. Choline is an essential nutrient that the body uses to make acetylcholine (a key memory neurotransmitter) and phosphatidylcholine (a building block of cell membranes), and it plays important roles in brain development, liver fat metabolism, and methylation.

Studied Dose Commonly 300 to 550 mg of choline per day.
Active Compound Choline L-bitartrate, a bioavailable salt of the essential nutrient choline.

Benefits

Brain and memory support

Choline is the precursor to acetylcholine, a neurotransmitter central to memory and attention, making it foundational for cognitive health.

Supported by Trial 1

Prenatal brain development

In a randomized controlled feeding study, maternal choline supplementation improved infant information-processing speed, highlighting choline's role in brain development.

Supported by Trial 1

Liver support

Choline is needed to export fat from the liver as phosphatidylcholine, supporting healthy liver fat metabolism.

Supported by Trial 1

Mechanism of action

1

Acetylcholine synthesis

Choline supplies the raw material for acetylcholine, the neurotransmitter used in memory, attention, and muscle control.

2

Phospholipid and methyl-donor roles

Choline builds phosphatidylcholine for cell membranes and contributes methyl groups (via betaine) to support healthy homocysteine metabolism.

Clinical trials

1
Maternal Choline and Infant Cognition — RCT
PubMed

Randomized, double-blind, controlled feeding study of maternal choline supplementation in the third trimester on infant cognition. (Caudill et al. 2018, FASEB Journal)

Pregnant women and their infants.

Higher maternal choline intake improved infant information-processing speed, underscoring choline's role in brain development.

Side effects and drug interactions

Common Potential side effects

GENERALLY WELL-TOLERATED — adverse effects are uncommon at normal doses.
Mild digestive upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

High doses can cause a fishy body odor, sweating, or digestive upset.
Stay within recommended intakes unless advised otherwise.
Tell your doctor if pregnant, breastfeeding, or managing a condition.

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Frequently asked questions about VitaCholine® (Choline Bitartrate — Balchem)

What is VitaCholine® (Choline Bitartrate — Balchem)?

VitaCholine® is a high-quality choline L-bitartrate from Balchem. Choline is an essential nutrient that the body uses to make acetylcholine (a key memory neurotransmitter) and phosphatidylcholine (a building block of cell membranes), and it plays important roles in brain development, liver fat metabolism, and methylati…

What is the recommended dosage of VitaCholine® (Choline Bitartrate — Balchem)?

The clinically studied dose for VitaCholine® (Choline Bitartrate — Balchem) is Commonly 300 to 550 mg of choline per day.. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is VitaCholine® (Choline Bitartrate — Balchem) used for?

VitaCholine® (Choline Bitartrate — Balchem) is studied for brain and memory support, prenatal brain development, liver support. Choline is the precursor to acetylcholine, a neurotransmitter central to memory and attention, making it foundational for cognitive health.

Are there side effects from taking VitaCholine® (Choline Bitartrate — Balchem)?

Reported potential side effects may include: GENERALLY WELL-TOLERATED — adverse effects are uncommon at normal doses. Mild digestive upset is occasionally reported. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Is VitaCholine® (Choline Bitartrate — Balchem) safe to take?

Whether VitaCholine® (Choline Bitartrate — Balchem) is safe depends on the dose, your overall health, and any medications you take. At studied doses, reported side effects can include: GENERALLY WELL-TOLERATED — adverse effects are uncommon at normal doses. It may also interact with certain medications. VitaCholine® (Choline Bitartrate — Balchem) is not suitable for everyone — consult a healthcare provider before use if you are pregnant or breastfeeding, have a medical condition, or take prescription medications.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Caudill MA, Strupp BJ, Muscalu L, et al. Maternal choline supplementation during the third trimester of pregnancy improves infant information processing speed: a randomized, double-blind, controlled feeding study. FASEB J. 2018;32(4):2172-2180..PubMedUsed to support: RCT supporting cognitive-development benefit of choline supplementation.