Cinaran® (Artichoke Leaf Extract)

Cinaran® is a standardized artichoke (Cynara scolymus) leaf extract concentrated for cynarin and chlorogenic acid. Artichoke has a long history as a digestive and liver tonic, and modern trials study it for supporting liver health, healthy cholesterol, and comfortable digestion by stimulating bile flow.

Cinaran is researched primarily for Liver Health, Cardiovascular, and Gut Health. In a single pilot double-blind randomized controlled trial in adults with non-alcoholic fatty liver disease (a disease population), artichoke leaf extract supported improvements in liver measures versus placebo.

The clinically studied dose is Commonly 600 mg to 1.8 g of extract per day. Always follow the product label and check with a healthcare provider for personal advice.

For most healthy adults, Cinaran is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — digestive effects are most common. Mild gas or cramping can occur from increased bile flow. It may also interact with some medications. Cinaran is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Possible interactions include: Bile-duct or gallbladder conditions — consult a doctor before use. Cholesterol medication — may have additive effects; monitor. If you take prescription medication, check with a pharmacist or doctor before using it.

NutraSmarts rates the evidence for Cinaran as Moderate (3 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.