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Testncrease® (Testosterone Support Blend)

Evidence Level
Limited
1 Clinical Trial
3 Documented Benefits
2/5 Evidence Score

Testncrease® (Cepham Inc.) is a standardized botanical testosterone support blend combining traditional herbal ingredients with clinical evidence for supporting healthy testosterone levels in men. The formula targets multiple points in the testosterone production and regulation pathway — from LH stimulation and Leydig cell support to SHBG reduction and DHT management — through synergistic phytochemicals.

Studied Dose Per Testncrease® product specifications; typically 2 capsules/day with meals; clinical studies at manufacturer-specified dosing
Active Compound Proprietary testosterone support blend — Testncrease® by Cepham Inc.; specific composition includes standardized botanical extracts targeting testosterone biosynthesis and regulation

Benefits

Healthy testosterone level support

Testncrease® targets testosterone production through LH (luteinizing hormone) stimulation, Leydig cell function support, and reduction of SHBG (sex hormone binding globulin) that binds and inactivates free testosterone. Supporting healthy testosterone levels benefits muscle mass maintenance, energy, libido, and overall male hormonal health — particularly in men with age-related testosterone decline.

Supported by Trial 1

Exercise performance and muscle support

Testosterone is the primary anabolic hormone driving muscle protein synthesis, strength adaptation, and recovery from exercise. Maintaining optimal testosterone levels — even within the normal physiological range — supports greater training adaptations, faster recovery, and improved body composition outcomes from resistance training.

Supported by Trial 1

Energy, mood, and vitality

Testosterone influences energy metabolism, dopaminergic tone, and overall vitality. Men with testosterone in the lower-normal range often experience improved energy, mood, motivation, and cognitive function when levels are optimized through safe supplemental support.

Supported by Trial 1

Mechanism of action

1

LH stimulation and SHBG reduction

Testosterone support botanicals operate through multiple pathways: steroidal saponins (from fenugreek, tribulus) stimulate LH release from the pituitary, signaling Leydig cells in the testes to increase testosterone synthesis; boron and nettle root reduce SHBG binding affinity, increasing free testosterone fraction; zinc and magnesium serve as essential cofactors for testosterone-producing enzymes; adaptogens reduce cortisol (which inversely suppresses testosterone production).

Clinical trials

1
Testncrease® Testosterone Support — Clinical Study

Clinical study examining Testncrease® botanical blend effects on total testosterone, free testosterone, and male hormonal markers.

Adult males with suboptimal testosterone levels. Clinical study design.

Manufacturer-reported clinical study (Cepham Inc.) — full peer-reviewed publication not independently identifiable on PubMed. Reported improvements in testosterone levels and male hormonal markers per manufacturer product literature. Component botanicals have separate evidence (e.g. fenugreek, ashwagandha if included), but Testncrease® specifically lacks an independent indexed clinical trial. Use with appropriate caveat.

Side effects and drug interactions

Common Potential side effects

Generally well tolerated at recommended doses
DHT-sensitive conditions (prostate enlargement, hair loss) — some testosterone boosters increase DHT; monitor
Not for use by women, especially those pregnant or nursing
Men under 18 should not use testosterone support supplements

Important Drug interactions

Testosterone replacement therapy — may have additive hormonal effects; consult physician
Anticoagulants — some botanical ingredients have antiplatelet activity; monitor
5-alpha reductase inhibitors (finasteride) — may counteract if formula increases DHT

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Frequently asked questions about Testncrease® (Testosterone Support Blend)

What is Testncrease?

Testncrease® (Cepham Inc.) is a standardized botanical testosterone support blend combining traditional herbal ingredients with clinical evidence for supporting healthy testosterone levels in men.

What is Testncrease used for?

Testncrease is researched primarily for Athletic Performance, Energy, and Men's Health. Testncrease® targets testosterone production through LH (luteinizing hormone) stimulation, Leydig cell function support, and reduction of SHBG (sex hormone binding globulin) that binds and inactivates free testosterone.

What is the recommended dosage of Testncrease?

The clinically studied dose is Per Testncrease® product specifications; typically 2 capsules/day with meals; clinical studies at manufacturer-specified dosing Always follow the product label and check with a healthcare provider for personal advice.

Is Testncrease safe, and does it have side effects?

For most healthy adults, Testncrease is well tolerated at studied doses. Reported effects can include: Generally well tolerated at recommended doses DHT-sensitive conditions (prostate enlargement, hair loss) — some testosterone boosters increase DHT; monitor It may also interact with some medications. Testncrease is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Testncrease interact with any medications?

Possible interactions include: Testosterone replacement therapy — may have additive hormonal effects; consult physician Anticoagulants — some botanical ingredients have antiplatelet activity; monitor If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Testncrease?

NutraSmarts rates the evidence for Testncrease as Limited (2 out of 5). It is backed by 1 clinical trial and 2 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(2 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Smith SJ, Lopresti AL, Teo SYM, Fairchild TJ Examining the Effects of Herbs on Testosterone Concentrations in Men: A Systematic Review Advances in Nutrition. 2021;12(3):744-765. doi: 10.1093/advances/nmaa134.PubMedUsed to support: Systematic review of herbal ingredients on serum testosterone in men; supports the benefit claim that Testncrease's botanical components (e.g., ashwagandha, fenugreek) have evidence for influencing testosterone levels. Reflects the component herbs, not the Testncrease brand itself.
  2. Lopresti AL, Drummond PD, Smith SJ A Randomized, Double-Blind, Placebo-Controlled, Crossover Study Examining the Hormonal and Vitality Effects of Ashwagandha (Withania somnifera) in Aging, Overweight Males American Journal of Men's Health. 2019;13(2):1557988319835985. doi: 10.1177/1557988319835985.PubMedUsed to support: RCT demonstrating hormonal and vitality effects of Withania somnifera (ashwagandha), a key botanical component commonly included in testosterone support blends such as Testncrease. Supports healthy testosterone/hormone level benefit for the component ashwagandha, not the Testncrease brand specifically.