StaiMune® (Inactivated Bacillus coagulans GBI-30 — Kerry)

Evidence Level
Preliminary
1 Clinical Trial
2 Documented Benefits
1/5 Evidence Score

StaiMune® is a postbiotic from Kerry made of inactivated (heat-killed) Bacillus coagulans GBI-30, 6086 cells. As a non-living postbiotic, it is shelf-stable and does not need refrigeration, and it is studied for supporting immune function through interaction with the gut immune system.

Studied Dose Around 0.5 to 1 billion inactivated cells per day.
Active Compound Inactivated (heat-killed) Bacillus coagulans GBI-30, 6086, a postbiotic that retains immune-signaling cell components.

Benefits

Immune support

In laboratory studies, the inactivated probiotic induced complex immune responses in human immune cells.

Gut-immune interaction

It engages the gut-associated immune system to help maintain a balanced immune response.

Mechanism of action

1

Immune cell activation

Components of the inactivated cells are recognized by immune cells, prompting a measured immune response without needing live colonization.

2

Postbiotic stability

Heat treatment preserves the bioactive cell structures that signal to the immune system while removing the need for live organisms.

Clinical trials

1
Inactivated Bacillus coagulans and Immune Response — In-Vitro (Laboratory) Study
PubMed

Laboratory study of inactivated Bacillus coagulans GBI-30 on human immune-cell responses. (Jensen et al. 2017, Journal of Inflammation Research)

Human immune cells (in vitro).

The inactivated probiotic induced complex immune responses in human immune cells, supporting its immune-modulating activity.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — postbiotics are non-living and very safe.
Mild digestive changes are possible when starting any gut supplement.
No live-organism infection risk.

Important Drug interactions

Immunosuppressants — an immune-stimulating postbiotic could in theory counteract them; use cautiously.
No significant interactions are expected.
Tell your doctor if you are immunocompromised.

Frequently asked questions about StaiMune® (Inactivated Bacillus coagulans GBI-30 — Kerry)

What is StaiMune?

StaiMune® is a postbiotic from Kerry made of inactivated (heat-killed) Bacillus coagulans GBI-30, 6086 cells. As a non-living postbiotic, it is shelf-stable and does not need refrigeration, and it is studied for supporting immune function through interaction with the gut immune system.

What is StaiMune used for?

StaiMune is researched primarily for Immune Support. In laboratory studies, the inactivated probiotic induced complex immune responses in human immune cells.

What is the recommended dosage of StaiMune?

The clinically studied dose is Around 0.5 to 1 billion inactivated cells per day. Always follow the product label and check with a healthcare provider for personal advice.

Is StaiMune safe, and does it have side effects?

For most healthy adults, StaiMune is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — postbiotics are non-living and very safe. Mild digestive changes are possible when starting any gut supplement. It may also interact with some medications. StaiMune is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does StaiMune interact with any medications?

Possible interactions include: Immunosuppressants — an immune-stimulating postbiotic could in theory counteract them; use cautiously. No significant interactions are expected. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for StaiMune?

NutraSmarts rates the evidence for StaiMune as Preliminary (1 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Jensen GS, Cash HA, Farmer S, et al. Inactivated probiotic Bacillus coagulans GBI-30 induces complex immune activating, anti-inflammatory, and regenerative markers in vitro. J Inflamm Res. 2017;10:107-117..PubMedUsed to support: In vitro evidence of immune-modulating activity.