Benefits
Menopausal symptom support
In a clinical study, flaxseed hull lignan extract supported relief of menopausal symptoms, offering a plant-based option for hormonal transition.
Hormone balance
Lignans have mild, balancing activity at estrogen receptors, which may help smooth the hormonal swings of perimenopause and menopause.
Antioxidant lignans
The lignans and their gut-derived metabolites act as antioxidants, supporting general and hormonal health.
Mechanism of action
Enterolignan conversion
Gut bacteria convert SDG into enterolactone and enterodiol, which weakly modulate estrogen receptors and support hormonal balance.
Selective estrogenic activity
The enterolignans can act as mild estrogen agonists or antagonists depending on the tissue, helping buffer hormonal fluctuations.
Clinical trials
Study of the efficacy and safety of a flaxseed hull extract for menopausal symptoms. (Simons et al. 2015, Journal of Medicinal Food)
Menopausal women.
The flaxseed hull lignan extract supported relief of menopausal symptoms with good tolerability.