Home Ingredients GivoCal® (Calcium)
Bone Health

GivoCal® (Calcium)

Evidence Level
Strong
1 Clinical Trial
3 Documented Benefits
4/5 Evidence Score

GivoCal® is a calcium ingredient for bone-health supplements and foods. Calcium is the body's main bone-building mineral, supporting bone strength and maintenance throughout life, especially with vitamin D.

Studied Dose Commonly 500 to 1200 mg of elemental calcium per day.
Active Compound Calcium (often with vitamin D and trace minerals for bone support).

Benefits

Bone strength

Calcium is the main structural mineral of bone; with vitamin D, supplementation supports bone mineral density and reduces bone loss.

Supported by Trial 1

Bone maintenance with age

Adequate calcium intake is essential throughout life to maintain a strong skeleton and reduce age-related bone loss.

Supported by Trial 1

Muscle and nerve support

Calcium also supports normal muscle contraction and nerve signaling.

Supported by Trial 1

Mechanism of action

1

Bone mineralization

Calcium combines with phosphate to form the hydroxyapatite crystals that give bone its hardness and strength.

2

Calcium homeostasis

The body tightly regulates blood calcium; adequate intake spares calcium from being drawn out of bone.

Clinical trials

1
Calcium and Vitamin D for Bone — Meta-Analysis
PubMed

Systematic review and meta-analysis of combined calcium and vitamin D supplementation on bone in postmenopausal women. (Liu et al. 2020, Food and Function)

Postmenopausal women across trials.

Combined calcium and vitamin D supported bone mineral density and reduced bone loss versus control.

Side effects and drug interactions

Common Potential side effects

Constipation, gas, or bloating can occur.
Take in divided doses (500 mg or less at a time) for best absorption.
Very high intake may raise kidney-stone risk in susceptible people.

Important Drug interactions

Antibiotics (tetracyclines, quinolones), thyroid medication, and bisphosphonates — separate by 2 to 4 hours.
Thiazide diuretics — monitor calcium levels.
Tell your doctor about all medications and your total calcium intake.

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Frequently asked questions about GivoCal® (Calcium)

What is GivoCal® (Calcium)?

GivoCal® is a calcium ingredient for bone-health supplements and foods. Calcium is the body's main bone-building mineral, supporting bone strength and maintenance throughout life, especially with vitamin D.

What is the recommended dosage of GivoCal® (Calcium)?

The clinically studied dose for GivoCal® (Calcium) is Commonly 500 to 1200 mg of elemental calcium per day.. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is GivoCal® (Calcium) used for?

GivoCal® (Calcium) is studied for bone strength, bone maintenance with age, muscle and nerve support. Calcium is the main structural mineral of bone; with vitamin D, supplementation supports bone mineral density and reduces bone loss.

Are there side effects from taking GivoCal® (Calcium)?

Reported potential side effects may include: Constipation, gas, or bloating can occur. Take in divided doses (500 mg or less at a time) for best absorption. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Is GivoCal® (Calcium) safe to take?

Whether GivoCal® (Calcium) is safe depends on the dose, your overall health, and any medications you take. At studied doses, reported side effects can include: Constipation, gas, or bloating can occur. It may also interact with certain medications. GivoCal® (Calcium) is not suitable for everyone — consult a healthcare provider before use if you are pregnant or breastfeeding, have a medical condition, or take prescription medications.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Liu C, Kuang X, Li K, et al. Effects of combined calcium and vitamin D supplementation on osteoporosis in postmenopausal women: a systematic review and meta-analysis of randomized controlled trials. Food Funct. 2020;11(12):10817-10827..PubMedUsed to support: Meta-analysis supporting bone benefit of calcium (the mineral in this branded calcium).