Gastrap® (Chitin-Glucan for Gas and Bloating — KitoZyme)

Evidence Level
Limited
0 Clinical Trials
3 Documented Benefits
2/5 Evidence Score

Gastrap® is a digestive-health ingredient from KitoZyme built on chitin-glucan, a non-animal fiber from the fungus Aspergillus niger. It is marketed to ease gas and bloating and to support a healthy gut microbiota, though clinical efficacy for symptom relief has not yet been demonstrated; it is the basis of finished products aimed at everyday digestive discomfort.

Studied Dose Per the product specification.
Active Compound Chitin-glucan, a non-animal insoluble prebiotic fiber from Aspergillus niger.

Benefits

Gas and bloating relief

Gastrap is marketed for intestinal gas and bloating, but no clinical efficacy trial has tested this outcome. The available human study (Neyrinck 2021) measured fermentation and tolerability rather than symptom relief, so a gas- or bloating-reducing effect remains unproven.

Microbiota restoration

The chitin-glucan fiber may act as a prebiotic substrate for beneficial gut bacteria; a microbiota-restoring effect has been seen in laboratory and rat studies but has not been demonstrated in human trials.

Digestive transit

Like other fermentable fibers, it supports healthy, regular transit through the gut.

Mechanism of action

1

Slow colonic fermentation

Chitin-glucan ferments gradually along the colon, producing short-chain fatty acids with a low level of gas while feeding beneficial bacteria.

2

Prebiotic microbiota support

By selectively nourishing beneficial bacteria, the fiber may serve as a prebiotic substrate for beneficial bacteria; an effect on bloating has not been established in clinical trials.

Clinical trials

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated as a fiber.
Mild gas or bloating can occur as intake rises.
Increase the dose gradually and drink plenty of water.

Important Drug interactions

No major drug interactions are established for this ingredient.
Tell your doctor about all supplements if you take prescription medication.
Use caution if pregnant, breastfeeding, or managing a health condition.

Frequently asked questions about Gastrap® (Chitin-Glucan for Gas and Bloating — KitoZyme)

What is Gastrap?

Gastrap® is a digestive-health ingredient from KitoZyme built on chitin-glucan, a non-animal fiber from the fungus Aspergillus niger. It is marketed to ease gas and bloating and to support a healthy gut microbiota, though clinical efficacy for symptom relief has not yet been demonstrated; it is the basis of finished pr…

What is Gastrap used for?

Gastrap is researched primarily for Gut Health. Gastrap is marketed for intestinal gas and bloating, but no clinical efficacy trial has tested this outcome. The available human study (Neyrinck 2021) measured fermentation and tolerability rather than symptom relief, so a gas- or bloating-…

What is the recommended dosage of Gastrap?

The clinically studied dose is Per the product specification. Always follow the product label and check with a healthcare provider for personal advice.

Is Gastrap safe, and does it have side effects?

For most healthy adults, Gastrap is well tolerated at studied doses. Reported effects can include: Generally well-tolerated as a fiber. Mild gas or bloating can occur as intake rises. It may also interact with some medications. Gastrap is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Gastrap interact with any medications?

Possible interactions include: No major drug interactions are established for this ingredient. Tell your doctor about all supplements if you take prescription medication. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Gastrap?

NutraSmarts rates the evidence for Gastrap as Limited (2 out of 5). It is backed by 2 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(2 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Neyrinck AM, Rodriguez J, Zhang Z, Seethaler B, Mailleux F, Vercammen J, Bindels LB, Cani PD, Nazare JA, Maquet V, Laville M, Bischoff SC, Walter J, Delzenne NM Noninvasive monitoring of fibre fermentation in healthy volunteers by analyzing breath volatile metabolites: lessons from the FiberTAG intervention study Gut Microbes. 2021;13(1):1-16. doi:10.1080/19490976.2020.1862028.PubMedUsed to support: Human crossover study with 15 healthy volunteers demonstrating a single 4.5 g dose of chitin-glucan (the active fiber in Gastrap from KitoZyme/Aspergillus niger) was well tolerated with no significant GI discomfort and produced fermentation metabolites including butyrate, indicating the fiber is fermented and generally tolerated. This does not demonstrate gas/bloating relief, improved transit, or microbiota-restoration efficacy, which were not endpoints. Note: evidence is for the chitin-glucan active; Gastrap brand not named.
  2. Alessandri G, Milani C, Duranti S, Mancabelli L, Ranjanoro T, Modica S, Carnevali L, Statello R, Bottacini F, Turroni F, Ossiprandi MC, Sgoifo A, van Sinderen D, Ventura M Ability of bifidobacteria to metabolize chitin-glucan and its impact on the gut microbiota Scientific Reports. 2019;9(1):5755. doi:10.1038/s41598-019-42257-z.PubMedUsed to support: In vitro and in vivo (rat) study demonstrating bifidobacteria selectively ferment chitin-glucan (the Gastrap active) and that dietary chitin-glucan enhances beneficial Bifidobacterium colonization and modulates gut microbial communities, supporting microbiota restoration claim. Note: results in rat model; human clinical data not yet available for Gastrap specifically.