Home Ingredients Fenavari® (Fenugreek + Shatavari Menopause Extract — OmniActive)
Menopause SupportWomen's Health

Fenavari® (Fenugreek + Shatavari Menopause Extract — OmniActive)

Trigonella foenum-graecum, Asparagus racemosus
Evidence Level
Limited
1 Clinical Trial
3 Documented Benefits
2/5 Evidence Score

Fenavari® is a branded botanical from OmniActive that combines standardized extracts of fenugreek (Trigonella foenum-graecum) and shatavari (Asparagus racemosus) in a single blend, standardized to about 4% protodioscin and 6% shatavarin IV. Launched in 2026, it is marketed as an integrated option for the menopausal transition. In its clinical trial, daily supplementation reduced overall menopause symptom scores more than placebo, with fewer hot flashes and night sweats and a shift toward higher estradiol and lower FSH. The evidence is currently a single manufacturer-sponsored trial on the finished blend, though the fenugreek component has its own separate menopause studies.

Studied Dose 300 to 500 mg once daily; the 500 mg dose worked better than 300 mg in the trial.
Active Compound Standardized fenugreek plus shatavari blend (about 4% protodioscin and 6% shatavarin IV).

Benefits

Fewer hot flashes and night sweats

In a 12-week dose-ranging trial, women taking Fenavari had significantly greater reductions in overall menopause symptom scores than placebo, including fewer and less intense hot flashes and night sweats, with the larger benefit at the higher dose.

Supported by Trial 1

Supports hormonal balance in midlife

By the end of the trial, Fenavari was associated with higher estradiol and lower follicle-stimulating hormone (FSH) compared with placebo, a shift consistent with easing the hormonal changes of the menopausal transition.

Supported by Trial 1

Supports sleep, mood, and calm

Alongside fewer vasomotor symptoms, the trial reported improvements in sleep quality, mood, and occasional feelings of anxiety, which are common concerns during perimenopause and menopause.

Supported by Trial 1

Mechanism of action

1

Plant compounds with gentle estrogen-like activity

Fenugreek saponins such as protodioscin and shatavari steroidal saponins (shatavarins) can interact weakly with estrogen pathways, which may help offset the decline in estrogen that drives many menopausal symptoms.

2

Shifts the estrogen-FSH balance

In the clinical study the blend was linked to higher estradiol and lower FSH, suggesting an effect on the hormonal feedback loop that becomes dysregulated during the menopausal transition.

3

Shatavari, a traditional women's tonic

Shatavari (Asparagus racemosus) has long been used in Ayurveda as a female reproductive tonic; its saponins are the rationale for pairing it with fenugreek for broader midlife support, though human data on shatavari alone are limited.

Clinical trials

1
Fenavari Dose-Ranging Menopause RCT
PubMed

Randomised, double-blind, parallel, placebo-controlled dose-ranging trial of Fenavari (standardized fenugreek plus shatavari) at 300 mg and 500 mg once daily for 84 days (Kashinath RN, Bhat VV, Morde A, Joshua L, Thomas JV 2026, Women's Health Reports 7, PMID 42539366).

150 women aged 40-60 with menopausal symptoms (138 completed); 300 mg, 500 mg, or placebo once daily.

Both doses reduced the total Menopause Rating Scale score significantly more than placebo (-8.26 at 300 mg and -10.40 at 500 mg versus -4.09; both p<0.0001), with fewer hot flashes and night sweats, higher estradiol, lower FSH, and better sleep and mood. A single manufacturer-sponsored trial on the branded blend.

Side effects and drug interactions

Common Potential side effects

Well-tolerated in the clinical trial, with no safety concerns reported.
Fenugreek can cause mild digestive upset and, in some people, a maple-syrup-like body or urine odor.
Fenugreek is a legume; people allergic to peanuts, chickpeas, or other legumes may react.
Not for use during pregnancy; fenugreek can stimulate the uterus and hormone-active botanicals are best avoided in pregnancy.

Important Drug interactions

Diabetes medications: fenugreek may lower blood sugar and could add to their effect; monitor.
Blood thinners such as warfarin: fenugreek contains coumarin-like compounds and may increase bleeding risk; use caution.
Hormone-sensitive conditions or hormone therapy: because the blend can shift estrogen and FSH, talk to your doctor if you have a hormone-sensitive condition or take hormone therapy.

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Frequently asked questions about Fenavari® (Fenugreek + Shatavari Menopause Extract — OmniActive)

What is Fenavari?

Fenavari® is a branded botanical from OmniActive that combines standardized extracts of fenugreek (Trigonella foenum-graecum) and shatavari (Asparagus racemosus) in a single blend, standardized to about 4% protodioscin and 6% shatavarin IV.

What is Fenavari used for?

Fenavari is researched primarily for Menopause Support and Women's Health. In a 12-week dose-ranging trial, women taking Fenavari had significantly greater reductions in overall menopause symptom scores than placebo, including fewer and less intense hot flashes and night sweats, with the larger benefit at the high…

What is the recommended dosage of Fenavari?

The clinically studied dose is 300 to 500 mg once daily; the 500 mg dose worked better than 300 mg in the trial. Always follow the product label and check with a healthcare provider for personal advice.

Is Fenavari safe, and does it have side effects?

For most healthy adults, Fenavari is well tolerated at studied doses. Reported effects can include: Well-tolerated in the clinical trial, with no safety concerns reported. Fenugreek can cause mild digestive upset and, in some people, a maple-syrup-like body or urine odor. It may also interact with some medications. Fenavari is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Fenavari interact with any medications?

Possible interactions include: Diabetes medications: fenugreek may lower blood sugar and could add to their effect; monitor. Blood thinners such as warfarin: fenugreek contains coumarin-like compounds and may increase bleeding risk; use caution. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Fenavari?

NutraSmarts rates the evidence for Fenavari as Limited (2 out of 5). It is backed by 1 clinical trial and 2 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(2 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Kashinath RN, Bhat VV, Morde A, Joshua L, Thomas JV. Dose-Dependent Efficacy of a Combined Standardized Extract of Fenugreek and Shatavari on Menopausal Symptoms: A Randomized, Double-Blind, Parallel, Placebo-Controlled Study. Women's Health Reports (New Rochelle). 2026;7:26884844261465161. doi:10.1177/26884844261465161.PubMedUsed to support: The pivotal (and so far only) trial of the branded Fenavari blend: in 150 women aged 40-60, 300 mg and 500 mg daily for 84 days reduced total Menopause Rating Scale scores significantly more than placebo (both p<0.0001), dose-dependently, with fewer hot flashes and night sweats and higher estradiol and lower FSH. Single manufacturer-sponsored RCT.
  2. Steels E, Steele ML, Harold M, Coulson S. Efficacy of a Proprietary Trigonella foenum-graecum L. De-Husked Seed Extract in Reducing Menopausal Symptoms in Otherwise Healthy Women: A Double-Blind, Randomized, Placebo-Controlled Study. Phytotherapy Research. 2017;31(9):1316-1322. doi:10.1002/ptr.5856.PubMedUsed to support: Independent double-blind RCT of a proprietary de-husked fenugreek seed extract showing reduced menopausal symptoms in otherwise healthy women. Supports the fenugreek component of Fenavari, though it tested a different fenugreek extract, not the Fenavari blend itself.