Factor21® (Bitter Melon Extract — Verdure Sciences)

Factor21® is a bitter melon (Momordica charantia) extract from Verdure Sciences, standardized to momordicosides and positioned to support energy metabolism through the FGF21 pathway and AMPK. Bitter melon is traditionally used to support healthy blood sugar, the basis for Factor21's metabolic positioning.

Factor21 is researched primarily for Metabolic Health and Weight Management. Bitter melon is studied for supporting healthy blood sugar and insulin sensitivity, the core of Factor21's metabolic positioning.

The clinically studied dose is Per the product specification. Always follow the product label and check with a healthcare provider for personal advice.

For most healthy adults, Factor21 is well tolerated at studied doses. Reported effects can include: Generally well-tolerated. Mild digestive upset is occasionally reported. It may also interact with some medications. Factor21 is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Possible interactions include: Diabetes medication — may add to blood-sugar lowering; monitor closely. Tell your doctor if you take insulin or other glucose-lowering drugs. If you take prescription medication, check with a pharmacist or doctor before using it.

NutraSmarts rates the evidence for Factor21 as Limited (2 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.