Chitoglucan® (Fungal Chitin-Glucan Fiber — Kitozyme)

Evidence Level
Limited
1 Clinical Trial
3 Documented Benefits
2/5 Evidence Score

Chitoglucan® is a fungal chitin-glucan fiber from the mycelium of Aspergillus niger, made by Kitozyme. It is an insoluble dietary fiber studied for binding fat and supporting healthy weight and lipid metabolism, offering a non-animal alternative to shellfish-derived chitosan.

Studied Dose Around 1.5 to 4.5 grams per day with meals.
Active Compound Chitin-glucan, an insoluble fiber complex of chitin and beta-glucan from fungal (Aspergillus niger) mycelium.

Benefits

Weight management

Chitin-glucan fiber is studied for supporting healthy body weight by binding some dietary fat and adding bulk, mostly in preclinical models so far.

Lipid support

By interfering with fat absorption and supporting fiber intake, it is researched for supporting healthy cholesterol and metabolic markers.

Vegetarian fiber

As a fungal-derived fiber, it offers a shellfish-free alternative to chitosan for fat-binding and gut support.

Mechanism of action

1

Fat binding

The fiber binds a portion of dietary fat in the gut, reducing its absorption and lowering the caloric and lipid load of meals.

2

Fiber bulking and fermentation

As a bulking fiber with a beta-glucan component, it supports satiety and feeds beneficial gut bacteria.

Clinical trials

1
Chitoglucan and Body Weight — Model Study
PubMed

Study of the anti-obesity effect of chitin-glucan fiber in a high-fat diet model. (Park et al. 2022, International Journal of Environmental Research and Public Health). Preclinical model.

High-fat-diet animal model.

Chitin-glucan supplementation reduced fat accumulation and body-weight gain in the model, providing the mechanistic rationale; human trials are limited.

Side effects and drug interactions

Common Potential side effects

GENERALLY WELL-TOLERATED as a dietary fiber.
Mild gas, bloating, or loose stools can occur with fat-binding fibers.
Take with plenty of water and separate from fat-soluble vitamins.

Important Drug interactions

Fat-soluble vitamins (A, D, E, K) — fat-binding fiber may reduce absorption; separate dosing.
Fat-soluble medications — separate by a few hours.
Tell your doctor if you take medication that needs dietary fat.

Frequently asked questions about Chitoglucan® (Fungal Chitin-Glucan Fiber — Kitozyme)

What is Chitoglucan® (Fungal Chitin-Glucan Fiber — Kitozyme)?

Chitoglucan® is a fungal chitin-glucan fiber from the mycelium of Aspergillus niger, made by Kitozyme. It is an insoluble dietary fiber studied for binding fat and supporting healthy weight and lipid metabolism, offering a non-animal alternative to shellfish-derived chitosan.

What is the recommended dosage of Chitoglucan® (Fungal Chitin-Glucan Fiber — Kitozyme)?

The clinically studied dose for Chitoglucan® (Fungal Chitin-Glucan Fiber — Kitozyme) is Around 1.5 to 4.5 grams per day with meals.. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is Chitoglucan® (Fungal Chitin-Glucan Fiber — Kitozyme) used for?

Chitoglucan® (Fungal Chitin-Glucan Fiber — Kitozyme) is studied for weight management, lipid support, vegetarian fiber. Chitin-glucan fiber is studied for supporting healthy body weight by binding some dietary fat and adding bulk, mostly in preclinical models so far.

Are there side effects from taking Chitoglucan® (Fungal Chitin-Glucan Fiber — Kitozyme)?

Reported potential side effects may include: GENERALLY WELL-TOLERATED as a dietary fiber. Mild gas, bloating, or loose stools can occur with fat-binding fibers. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Is Chitoglucan® (Fungal Chitin-Glucan Fiber — Kitozyme) safe to take?

Whether Chitoglucan® (Fungal Chitin-Glucan Fiber — Kitozyme) is safe depends on the dose, your overall health, and any medications you take. At studied doses, reported side effects can include: GENERALLY WELL-TOLERATED as a dietary fiber. It may also interact with certain medications. Chitoglucan® (Fungal Chitin-Glucan Fiber — Kitozyme) is not suitable for everyone — consult a healthcare provider before use if you are pregnant or breastfeeding, have a medical condition, or take prescription medications.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Park HJ, Lee S, Ye M, et al. Anti-Obesity Effect of Chitoglucan in High-Fat-Induced Obesity Mice. Int J Environ Res Public Health. 2022;20(1)..PubMedUsed to support: Model study supporting weight-management rationale.