Home Ingredients MBP® (Milk Basic Protein)
Bone Health

MBP® (Milk Basic Protein)

Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

MBP® (Milk Basic Protein) is a fraction of whey protein concentrated for the bone-active proteins of milk. Unlike calcium, which supplies raw material, MBP acts on the bone-building and bone-resorbing cells themselves, and clinical trials found it increased bone mineral density in healthy adults.

Studied Dose About 40 mg of milk basic protein per day.
Active Compound Milk basic protein (MBP), a concentrated fraction of whey basic proteins including lactoferrin and other bone-active proteins.

Benefits

Bone mineral density

In randomized trials, milk basic protein increased bone mineral density in healthy young women, supporting its bone-strengthening positioning.

Supported by Trial 1

Bone metabolism support

MBP improves markers of bone metabolism, favoring bone formation over breakdown.

Supported by Trial 1

Everyday bone health

By acting directly on bone cells, MBP complements calcium and vitamin D for long-term bone maintenance.

Supported by Trial 1

Mechanism of action

1

Osteoblast stimulation

Milk basic proteins promote the activity of osteoblasts, the cells that build new bone.

2

Reduced bone resorption

MBP suppresses osteoclasts, the cells that break down bone, shifting the remodeling balance toward bone gain.

Clinical trials

1
Milk Basic Protein and Bone Density — RCT
PubMed

Randomized trial of milk basic protein on bone mineral density and bone metabolism in healthy young women. (Uenishi et al. 2007, Osteoporosis International)

Healthy young women.

Milk basic protein increased bone mineral density and improved bone-metabolism markers versus placebo.

Side effects and drug interactions

Common Potential side effects

GENERALLY WELL-TOLERATED — derived from milk protein.
Mild digestive upset is occasionally reported.
Avoid if you have a milk-protein allergy.

Important Drug interactions

No major drug interactions are established for this ingredient.
Tell your doctor about all supplements if you take prescription medication.
Use caution if pregnant, breastfeeding, or managing a health condition.

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Frequently asked questions about MBP® (Milk Basic Protein)

What is MBP® (Milk Basic Protein)?

MBP® (Milk Basic Protein) is a fraction of whey protein concentrated for the bone-active proteins of milk. Unlike calcium, which supplies raw material, MBP acts on the bone-building and bone-resorbing cells themselves, and clinical trials found it increased bone mineral density in healthy adults.

What is the recommended dosage of MBP® (Milk Basic Protein)?

The clinically studied dose for MBP® (Milk Basic Protein) is About 40 mg of milk basic protein per day.. Always follow product labeling and consult a healthcare provider for personalized dosing recommendations.

What is MBP® (Milk Basic Protein) used for?

MBP® (Milk Basic Protein) is studied for bone mineral density, bone metabolism support, everyday bone health. In randomized trials, milk basic protein increased bone mineral density in healthy young women, supporting its bone-strengthening positioning.

Are there side effects from taking MBP® (Milk Basic Protein)?

Reported potential side effects may include: GENERALLY WELL-TOLERATED — derived from milk protein. Mild digestive upset is occasionally reported. Always consult a healthcare provider before starting any new supplement, especially if you have underlying conditions or take medications.

Is MBP® (Milk Basic Protein) safe to take?

Whether MBP® (Milk Basic Protein) is safe depends on the dose, your overall health, and any medications you take. At studied doses, reported side effects can include: GENERALLY WELL-TOLERATED — derived from milk protein. It may also interact with certain medications. MBP® (Milk Basic Protein) is not suitable for everyone — consult a healthcare provider before use if you are pregnant or breastfeeding, have a medical condition, or take prescription medications.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Uenishi K, Ishida H, Toba Y, et al. Milk basic protein increases bone mineral density and improves bone metabolism in healthy young women. Osteoporos Int. 2007;18(3):385-90..PubMedUsed to support: RCT supporting bone-density benefit of milk basic protein.