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GivoMag® (Magnesium)

Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

GivoMag® is a magnesium ingredient for supplements and functional foods. Magnesium is an essential mineral involved in hundreds of body processes, from muscle and nerve function to blood pressure and bone health, and many people do not get enough from diet alone. The evidence below reflects magnesium as a nutrient (its class evidence); no GivoMag-specific human efficacy trial has been published.

Studied Dose Commonly 200 to 400 mg of elemental magnesium per day.
Active Compound Magnesium, an essential dietary mineral (delivered as a magnesium salt).

Benefits

Healthy blood pressure

A meta-analysis of randomized trials found magnesium supplementation modestly lowered blood pressure, supporting cardiovascular health.

Supported by Trial 1

Muscle and nerve function

Magnesium supports normal muscle relaxation and nerve signaling, helping reduce cramps and tension.

Supported by Trial 1

Bone and sleep support

Magnesium contributes to bone structure and supports a calm nervous system and restful sleep.

Supported by Trial 1

Mechanism of action

1

Enzyme cofactor

Magnesium is a cofactor for hundreds of enzymes governing energy production, muscle function, and nerve transmission.

2

Vascular and calcium balance

Magnesium helps relax blood vessels and balances calcium's actions in muscle and nerve cells.

Clinical trials

1
Magnesium and Blood Pressure — Meta-Analysis
PubMed

Meta-analysis of randomized double-blind placebo-controlled trials of magnesium supplementation on blood pressure. (Zhang et al. 2016, Hypertension)

Adults across multiple trials.

Magnesium supplementation modestly lowered blood pressure versus placebo.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — loose stools are the most common effect at higher doses.
Reduce the dose if digestive upset occurs.
Severe kidney disease requires medical supervision.

Important Drug interactions

Antibiotics (tetracyclines, quinolones) and bisphosphonates — magnesium reduces absorption; separate by 2 hours.
Severe kidney disease — consult a doctor before magnesium.
Tell your doctor about all medications.

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Frequently asked questions about GivoMag® (Magnesium)

What is GivoMag?

GivoMag® is a magnesium ingredient for supplements and functional foods. Magnesium is an essential mineral involved in hundreds of body processes, from muscle and nerve function to blood pressure and bone health, and many people do not get enough from diet alone.

What is GivoMag used for?

GivoMag is researched primarily for Cardiovascular, Muscle & Recovery, and Bone Health. A meta-analysis of randomized trials found magnesium supplementation modestly lowered blood pressure, supporting cardiovascular health.

What is the recommended dosage of GivoMag?

The clinically studied dose is Commonly 200 to 400 mg of elemental magnesium per day. Always follow the product label and check with a healthcare provider for personal advice.

Is GivoMag safe, and does it have side effects?

For most healthy adults, GivoMag is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — loose stools are the most common effect at higher doses. Reduce the dose if digestive upset occurs. It may also interact with some medications. GivoMag is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does GivoMag interact with any medications?

Possible interactions include: Antibiotics (tetracyclines, quinolones) and bisphosphonates — magnesium reduces absorption; separate by 2 hours. Severe kidney disease — consult a doctor before magnesium. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for GivoMag?

NutraSmarts rates the evidence for GivoMag as Moderate (3 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Zhang X, Li Y, Del Gobbo LC, et al. Effects of Magnesium Supplementation on Blood Pressure: A Meta-Analysis of Randomized Double-Blind Placebo-Controlled Trials. Hypertension. 2016;68(2):324-33..PubMedUsed to support: Meta-analysis supporting blood-pressure benefit of magnesium.