Home Ingredients Gastro-AD® (Fermented Soy Postbiotic — Lallemand)
Gut Health

Gastro-AD® (Fermented Soy Postbiotic — Lallemand)

Evidence Level
Limited
0 Clinical Trials
3 Documented Benefits
2/5 Evidence Score

Gastro-AD® is a postbiotic from non-GMO soy fermented by the bacterium Lactobacillus delbrueckii, from Lallemand. With a heritage dating back decades, it is used to support stomach comfort, including during occasional heartburn and the discomfort of a sensitive stomach.

Studied Dose Per the product specification.
Active Compound Postbiotic of non-GMO soy fermented by Lactobacillus delbrueckii (inanimate cells plus fermentation metabolites).

Benefits

Stomach comfort

Gastro-AD is studied for supporting stomach comfort and supporting comfort in people with an occasionally irritated or sensitive stomach, including discomfort and heartburn.

Stomach-acid balance

Laboratory profiling has identified anti-inflammatory metabolites in the postbiotic; a direct effect on stomach-acid secretion has not been demonstrated in the cited research.

Long safety record

Fermented soy postbiotics such as Gastro-AD have a long history of dietary use and a good tolerability profile.

Mechanism of action

1

Postbiotic metabolites

The fermentation produces peptides and metabolites that, in laboratory studies, may help modulate inflammatory signaling; direct effects on the human stomach lining are not yet established.

2

Acid-secretion modulation

Postbiotic metabolites are hypothesized to help support balanced stomach-acid levels, but this mechanism has not been confirmed for Gastro-AD in the cited research.

Clinical trials

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Contains soy; avoid if you have a soy allergy.
See a doctor for persistent stomach pain to rule out other causes.

Important Drug interactions

Acid-reducing medication — tell your doctor if combining.
Generally compatible with other medications.
Tell your doctor if you have a diagnosed stomach condition.

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Frequently asked questions about Gastro-AD® (Fermented Soy Postbiotic — Lallemand)

What is Gastro-AD?

Gastro-AD® is a postbiotic from non-GMO soy fermented by the bacterium Lactobacillus delbrueckii, from Lallemand. With a heritage dating back decades, it is used to support stomach comfort, including during occasional heartburn and the discomfort of a sensitive stomach.

What is Gastro-AD used for?

Gastro-AD is researched primarily for Gut Health. Gastro-AD is studied for supporting stomach comfort and supporting comfort in people with an occasionally irritated or sensitive stomach, including discomfort and heartburn.

What is the recommended dosage of Gastro-AD?

The clinically studied dose is Per the product specification. Always follow the product label and check with a healthcare provider for personal advice.

Is Gastro-AD safe, and does it have side effects?

For most healthy adults, Gastro-AD is well tolerated at studied doses. Reported effects can include: Generally well-tolerated. Contains soy; avoid if you have a soy allergy. It may also interact with some medications. Gastro-AD is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Gastro-AD interact with any medications?

Possible interactions include: Acid-reducing medication — tell your doctor if combining. Generally compatible with other medications. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Gastro-AD?

NutraSmarts rates the evidence for Gastro-AD as Limited (2 out of 5). It is backed by 2 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(2 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Ethier R, Krishnamurthy A, Jeffrey M, Tompkins TA Profiling of Metabolites in a Fermented Soy Dietary Supplement Reinforces its Role in the Management of Intestinal Inflammation Molecular Nutrition & Food Research. 2024;68(7):e2300770. doi:10.1002/mnfr.202300770.PubMedUsed to support: Metabolite profiling of Gastro-AD specifically (soy fermented by Lactobacillus delbrueckii R0187, from Lallemand) identifying bioactive isoflavones and short-chain fatty acids capable of modulating anti-inflammatory signaling in gastric and neuroendocrine tissues, providing a preliminary mechanistic basis for stomach-comfort research (the study measured no acid parameter and concerned intestinal, not gastric, inflammation).
  2. Liu CF, Hu CL, Chiang SS, Tseng KC, Yu RC, Pan TM Beneficial preventive effects of gastric mucosal lesion for soy-skim milk fermented by lactic acid bacteria Journal of Agricultural and Food Chemistry. 2009;57(10):4433-8. doi:10.1021/jf900465c.PubMedUsed to support: Animal study showing soy fermented by lactic acid bacteria reduced gastric lesion index, decreased lipid peroxidation in gastric mucosa, and enhanced prostaglandin E2 synthesis in a rat gastric-damage model, providing mechanism basis for stomach comfort claim. Note: animal study; the fermentation strain differs from Gastro-AD's L. delbrueckii R0187.