Fibregum™ (Prebiotic Acacia Gum)

Acacia senegal / Acacia seyal
Evidence Level
Limited
2 Clinical Trials
6 Documented Benefits
2/5 Evidence Score

Fibregum™ is a prebiotic acacia gum developed by Nexira (France) — supplied at a stated 90%+ soluble dietary fiber content. Human trials of acacia gum report good digestive tolerance at 10-20 g/day, but 30-40 g doses have produced diarrhea, nausea and bloating in some trials, and no head-to-head trial has shown better tolerance than FOS or inulin. Acacia gum is harvested as natural exudate from acacia tree stems and branches — sustainable, non-destructive harvesting. Used for fiber enrichment in foods/beverages/supplements with minimal sensory impact (odorless, colorless, tasteless in solution).

Studied Dose Trials used 5, 10, 20, 30 and 40 g/day; about 10 g/day was optimal in the one dose-response study. 30-40 g/day has caused GI symptoms.
Active Compound Acacia gum (arabinogalactan polysaccharide with proteinaceous core)

Benefits

Generally Good Digestive Tolerance

Acacia gum ferments slowly rather than rapidly. In a 12-week trial at 20 g/day, more participants reported a reduction in bloating than in the control group (52% vs 20%). Tolerance is not unlimited: 40 g taken with a single meal produced significantly more bloating, flatulence and gut rumbling than control, and in a 6-week trial at 30 g/day, 90% of participants reported diarrhea (vs 18% on the comparator fiber) and 82% nausea during the first week. The one study that included an inulin comparator arm reported no significant drawbacks on either fiber, so a tolerance advantage over inulin has not been demonstrated.

90%+ Soluble Fiber Content

A manufacturer composition specification rather than a measured health outcome. In the United States, acacia (gum arabic) may be declared as dietary fiber on the Nutrition Facts panel under FDA enforcement discretion following a December 2021 decision, pending rulemaking to revise the dietary fiber definition in 21 CFR 101.9.

Prebiotic Activity (Bifidobacterium and Lactobacillus)

One 4-week dose-response study in healthy volunteers found higher stool Bifidobacteria and Lactobacilli on gum arabic than on water, with about 10 g/day the optimal dose. A separate 12-week trial of an acacia gum and carrot powder mixture shifted microbiome composition but did not raise fecal short-chain fatty acids and did not change any clinical outcome. A change in bacterial counts is a laboratory measurement, not a health benefit in itself.

Self-Reported Bowel Comfort

In a 12-week trial in adults at risk of metabolic syndrome, more people taking 20 g/day gum arabic reported improved bowel movements (55% vs 33%) and less bloating (52% vs 20%) than those on the control. These are self-reported ratings in a single-blind study. No improvement in intestinal barrier function specific to acacia gum has been demonstrated in people: in the one human trial that measured gut barrier markers alongside acacia gum, they improved equally on a non-fermentable comparator fiber.

Glycemic Index Near Zero

Acacia gum is not digested in the small intestine and contributes no glucose itself. Its effect on the glucose response to a meal is small: in a 48-person crossover, glucose area-under-the-curve did not differ between 0, 20 and 40 g doses, and only the 20 g dose was lower than control at the 30-minute point.

Satiety / Weight Management Support

In a 48-person crossover, 40 g of acacia gum with breakfast reduced hunger and increased fullness at several points over the following 4 hours, and acute studies of gum arabic blends have shown lower energy intake at a meal 3 hours later. These are single-meal appetite measurements. No trial has shown sustained weight loss from gum arabic on a between-group comparison against placebo.

Mechanism of action

1

Slow Distal Colonic Fermentation

Acacia gum ferments slowly across the entire colon — different from FOS/inulin which ferment rapidly in proximal colon. Slow fermentation = less gas production, less bloating, gentler on GI. Reaches distal colon (less commonly fed by other prebiotics).

2

Bifidogenic Effect

Raises stool Bifidobacterium and Lactobacillus counts in healthy volunteers. The consensus definition of a prebiotic requires both selective use by gut microbes and a demonstrated health benefit for the host; for acacia gum the bacterial shift is the better-documented half.

3

SCFA Production

Fermentation produces acetate, propionate, butyrate; supports colonocyte health, gut barrier, immune function.

4

Gut Barrier / Tight Junction Effects — Not Demonstrated in People

Tight-junction and barrier-integrity effects have been described in animal and cell models. In the one human trial that measured gut barrier markers in people taking acacia gum, those markers improved just as much on a non-fermentable comparator fiber, so no barrier effect specific to acacia gum has been shown in people.

5

Low Hygroscopicity / Low Viscosity

Despite being soluble fiber, Fibregum™ has unusually low viscosity and low hygroscopicity — allows high fiber claim with minimal sensory impact in foods/beverages.

Clinical trials

1
Gum Arabic Prebiotic Dose-Response — Calame 2008
PubMed

Study in healthy volunteers comparing 5, 10, 20 and 40 g/day of a commercial gum arabic (EmulGold) in water for up to 4 weeks, against a water negative control and a 10 g inulin positive control, with stool bacteria quantified by real-time PCR. Conducted and authored by staff of the ingredient supplier; the gum tested was not Fibregum.

Healthy adult volunteers.

After 4 weeks, Bifidobacteria and Lactobacilli counts were significantly higher than on the water control, with about 10 g/day the optimal dose; at that dose counts were also higher than on 10 g inulin, as were counts of Bacteroides, which the study classed as potentially non-beneficial. No significant drawbacks were reported at any dose up to 40 g/day. The outcome measured was a shift in stool bacterial counts, not a clinical health outcome.

2
Acacia Gum Fiber, Microbiome and Health Outcomes — Eveleens Maarse 2024
PubMed

Randomized, double-blind, placebo-controlled crossover trial of a daily mixture of acacia gum and carrot powder versus placebo for 12 weeks, with an 8-week washout. Fecal microbiome and short-chain fatty acids were measured every 4 weeks, and metabolic and inflammatory resilience with a standardized mixed-meal challenge before and after each period.

65 healthy adults aged 45-70 with BMI 25-30 and low to moderate habitual fiber intake.

Microbiome composition changed (beta-diversity rose; alpha-diversity was lower than placebo at 4, 8 and 12 weeks), but fecal short-chain fatty acid concentrations did not change and neither pre-specified clinical outcome — inflammatory resilience and metabolic resilience — improved. Acacia gum was given as part of a mixture, so its individual contribution cannot be separated.

Side effects and drug interactions

Common Potential side effects

Generally well tolerated at 10-20 g/day.
Bloating, flatulence and gut rumbling increase significantly at 40 g taken in one sitting. In a 6-week trial at 30 g/day, first-week symptoms affected most participants: diarrhea 90% (vs 18% on the comparator fiber), nausea 82%, bloating 15%, and an unpleasant viscous mouth sensation 100%; symptoms settled after the first week.
Allergic reactions to acacia rare.
Pollen-allergic individuals (acacia pollen) may have cross-reactivity (rare).
Always dissolve in water before drinking. Acacia gum forms a low-viscosity solution rather than a gel, so choking and obstruction risk is lower than with psyllium or glucomannan, but no fiber powder should be swallowed dry.

Important Drug interactions

Generally minimal drug interactions.
Fiber may delay medication absorption — separate by 1-2 hours.
Diabetes medications — effects on blood glucose have been small and inconsistent in trials, so a clinically important additive effect is unlikely; monitor if you take glucose-lowering drugs.
Blood lipids — total cholesterol, LDL, HDL and triglycerides did not change in either group over 12 weeks at 20 g/day, so no meaningful interaction with lipid-lowering therapy is expected.
Pregnancy/lactation — acacia gum has long been used as a food additive and EFSA concluded in 2017 that no numerical acceptable daily intake is needed for E 414, but supplement doses of 10-40 g/day have not been studied in pregnancy or breastfeeding.
Children — acacia gum is permitted in foods for children, but supplement-level doses have not been tested in healthy children; check with a pediatrician first.

Frequently asked questions about Fibregum™ (Prebiotic Acacia Gum)

What is Fibregum?

Fibregum™ is a prebiotic acacia gum developed by Nexira (France) — supplied at a stated 90%+ soluble dietary fiber content. Human trials of acacia gum report good digestive tolerance at 10-20 g/day, but 30-40 g doses have produced diarrhea, nausea and bloating in some trials, and no head-to-head trial has shown better…

What is Fibregum used for?

Fibregum is researched primarily for Gut Health. Acacia gum ferments slowly rather than rapidly. In a 12-week trial at 20 g/day, more participants reported a reduction in bloating than in the control group (52% vs 20%).

What is the recommended dosage of Fibregum?

The clinically studied dose is Trials used 5, 10, 20, 30 and 40 g/day; about 10 g/day was optimal in the one dose-response study. 30-40 g/day has caused GI symptoms. Always follow the product label and check with a healthcare provider for personal advice.

Is Fibregum safe, and does it have side effects?

For most healthy adults, Fibregum is well tolerated at studied doses. Reported effects can include: Generally well tolerated at 10-20 g/day. Bloating, flatulence and gut rumbling increase significantly at 40 g taken in one sitting. In a 6-week trial at 30 g/day, first-week symptoms affected most participants: diarrhea 90% (vs 18% on the comparator fiber), nausea 82%, bloating 1… It may also interact with some medications. Fibregum is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Fibregum interact with any medications?

Possible interactions include: Generally minimal drug interactions. Fiber may delay medication absorption — separate by 1-2 hours. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Fibregum?

NutraSmarts rates the evidence for Fibregum as Limited (2 out of 5). It is backed by 2 clinical trials and 9 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(9 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Calame W, Weseler AR, Viebke C, Flynn C, Siemensma AD. Gum arabic establishes prebiotic functionality in healthy human volunteers in a dose-dependent manner. Br J Nutr. 2008;100(6):1269-75. doi: 10.1017/S0007114508981447.PubMedUsed to support: Healthy volunteers took 5, 10, 20 or 40 g/day of a commercial gum arabic (EmulGold) in water for up to 4 weeks, against a water control and a 10 g inulin comparator. After 4 weeks, stool Bifidobacteria and Lactobacilli were significantly higher than on water, with about 10 g/day the optimal dose, and no significant drawback was reported at any dose. The outcome was a shift in stool bacterial counts rather than a clinical health outcome, the gum tested was not Fibregum, and the authors were staff of the company supplying it.
  2. Larson R, Nelson C, Korczak R, Willis H, Erickson J, Wang Q, Slavin J. Acacia Gum Is Well Tolerated While Increasing Satiety and Lowering Peak Blood Glucose Response in Healthy Human Subjects. Nutrients. 2021;13(2):618. doi: 10.3390/nu13020618.PubMedUsed to support: Randomized crossover in 48 healthy adults given 0, 20 or 40 g of acacia gum with a single breakfast. The 40 g dose reduced hunger and increased fullness at several timepoints over 4 hours, but glucose area-under-the-curve did not differ between doses and only the 20 g dose was below control at the 30-minute point. Subjects reported significantly more bloating, flatulence and gut rumbling on 40 g than on control, though absolute symptom scores were low. A single-meal acute study, funded by Nexira; no microbiome outcome was measured.
  3. Babiker R, Merghani TH, Elmusharaf K, Badi RM, Lang F, Saeed AM. Effects of Gum Arabic ingestion on body mass index and body fat percentage in healthy adult females: two-arm randomized, placebo controlled, double-blind trial. Nutr J. 2012;11:111. doi: 10.1186/1475-2891-11-111.PubMedUsed to support: 120 healthy women took either 30 g/day gum arabic or 1 g/day pectin for 6 weeks. The reported falls in BMI (0.32 kg/m2) and body fat (2.18 percentage points) are before-and-after comparisons within the gum arabic group; the paper reports no between-group test of these endpoints, and body weight itself did not change significantly (mean difference 1.24%, 95% CI -0.70 to 3.18). First-week side effects in the gum arabic group were common: an unfavorable viscous mouth sensation in 100%, diarrhea in 90% (vs 18% on pectin), nausea in 82% and bloating in 15%. The 100%-versus-0% split on mouth sensation means the intended double blind did not hold.
  4. Jarrar AH, Stojanovska L, Apostolopoulos V, Feehan J, Bataineh MF, Ismail LC, Al Dhaheri AS. The Effect of Gum Arabic (Acacia Senegal) on Cardiovascular Risk Factors and Gastrointestinal Symptoms in Adults at Risk of Metabolic Syndrome: A Randomized Clinical Trial. Nutrients. 2021;13(1):194. doi: 10.3390/nu13010194.PubMedUsed to support: Single-blind randomized trial in 80 adults with or at risk of metabolic syndrome, 61 of whom completed: 20 g/day gum arabic or 1 g/day pectin for 12 weeks. Between groups, more people on gum arabic reported improved bowel movements (54.8% vs 33.3%, p=0.047) and reduced bloating (51.6% vs 20.0%, p=0.005). Blood pressure and fasting glucose fell within the gum arabic group, but fasting glucose did not differ between groups at week 12, and HbA1c, triglycerides, total cholesterol, LDL and HDL did not change in either group. The gum arabic group also cut carbohydrate and energy intake, which confounds the metabolic readings.
  5. Calame W, Thomassen F, Hull S, Viebke C, Siemensma AD. Evaluation of satiety enhancement, including compensation, by blends of gum arabic. A methodological approach. Appetite. 2011;57(2):358-64. doi: 10.1016/j.appet.2011.06.005.PubMedUsed to support: Two acute studies in healthy adults given blends of gum arabic (EmulGold and PreVitae) dissolved in 250 ml water. Doses of 5 to 40 g raised subjective satiety ratings against the water control and cut energy intake at a meal 3 hours later — by more than 60 kcal at 5-10 g of EmulGold, and at 40 g by more than 100 kcal for EmulGold and more than 200 kcal for PreVitae. These are single-dose appetite and energy-intake measurements rather than body weight over time, from the same industry-linked authors as the 2008 dose-response study.
  6. Min YW, Park SU, Jang YS, Kim YH, Rhee PL, Ko SH, Joo N, Kim SI, Kim CH, Chang DK. Effect of composite yogurt enriched with acacia fiber and Bifidobacterium lactis. World J Gastroenterol. 2012;18(33):4563-9. doi: 10.3748/wjg.v18.i33.4563.PubMedUsed to support: 130 adults with irritable bowel syndrome took, twice daily for 8 weeks, either a yogurt containing acacia dietary fiber plus high-dose Bifidobacterium lactis or a control yogurt. Improvements in bowel-habit satisfaction (27.16 vs 15.51, p=0.010) and overall symptom scores (64.2 vs 50.4, p<0.001) were larger in the test group. Because the test product combined acacia fiber with a probiotic, the contribution of acacia fiber on its own cannot be determined.
  7. Gibson GR, Hutkins R, Sanders ME, Prescott SL, Reimer RA, Salminen SJ, Scott K, Stanton C, Swanson KS, Cani PD, Verbeke K, Reid G. Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics. Nat Rev Gastroenterol Hepatol. 2017;14(8):491-502. doi: 10.1038/nrgastro.2017.75.PubMedUsed to support: The international expert consensus definition of a prebiotic: a substrate that is selectively utilized by host microorganisms conferring a health benefit. Under this definition, a measured rise in Bifidobacteria or Lactobacilli is not on its own sufficient to call an ingredient a prebiotic; a demonstrated benefit to the host is also required.
  8. Suresh H, Zhou J, Ho V. The Short-Term Effects and Tolerability of Low-Viscosity Soluble Fibre on Gastroparesis Patients: A Pilot Clinical Intervention Study. Nutrients. 2021;13(12):4298. doi: 10.3390/nu13124298.PubMedUsed to support: Randomized crossover pilot in 10 women with mild-to-moderate gastroparesis comparing single doses of gum arabic, partially hydrolyzed guar gum, psyllium husk and water. Gum arabic moderated post-meal blood glucose comparably to psyllium while producing symptom scores equivalent to the water control, and did not markedly delay mouth-to-cecum transit. A very small single-dose pilot in a specific patient group.
  9. Eveleens Maarse BC, Eggink HM, Warnke I, Bijlsma S, van den Broek TJ, Oosterman JE, Caspers MPM, Sybesma W, Gal P, van Kraaij SJW, Schuren FHJ, Moerland M, Hoevenaars FPM. Impact of fibre supplementation on microbiome and resilience in healthy participants: A randomized, placebo-controlled clinical trial. Nutr Metab Cardiovasc Dis. 2024;34(6):1416-1426. doi: 10.1016/j.numecd.2024.01.028.PubMedUsed to support: Randomized, double-blind crossover trial in 65 healthy adults aged 45-70 with raised metabolic risk, taking a daily mixture of acacia gum and carrot powder or placebo for 12 weeks. Fecal microbiome composition changed (beta-diversity rose, alpha-diversity fell versus placebo at 4, 8 and 12 weeks), but fecal short-chain fatty acid concentrations did not change and neither pre-specified clinical outcome, inflammatory resilience or metabolic resilience, improved, nor did fasting metabolic and inflammatory state. Acacia gum was given as part of a mixture, so its individual contribution cannot be separated.