Ferractiv® (Iron Amino Acid Chelate — Biotron)

Evidence Level
Strong
1 Clinical Trial
3 Documented Benefits
4/5 Evidence Score

Ferractiv® is an iron amino acid chelate from Biotron Laboratories, designed to be gentler on the stomach than ferrous sulfate while remaining highly absorbable. As a chelated iron, it supports healthy iron levels, red blood cell formation, and the energy that depends on good iron status.

Studied Dose Commonly providing the daily iron requirement (around 18 mg, or more if correcting a deficiency under medical guidance).
Active Compound Iron bound to amino acids (iron amino acid chelate).

Benefits

Healthy iron levels

Iron is essential for healthy red blood cells and oxygen transport; supplementing supports normal iron status and helps correct iron-deficiency anemia.

Energy and reduced fatigue

Because iron carries oxygen to tissues, restoring healthy iron levels helps reduce the fatigue and weakness of iron deficiency.

Gentler, well-absorbed form

As an amino acid chelate, Ferractiv is designed to be better tolerated than ferrous sulfate while remaining highly bioavailable.

Mechanism of action

1

Oxygen transport

Iron is the core of hemoglobin, the protein in red blood cells that carries oxygen from the lungs to the rest of the body.

2

Chelated absorption

Binding iron to amino acids protects it through the gut and supports steady absorption with less of the irritation caused by plain iron salts.

Clinical trials

1
Iron Amino Acid Chelate for Iron Status — Meta-Analysis
PubMed

Systematic review and meta-analysis of ferrous bisglycinate (iron amino acid chelate) on hemoglobin and ferritin. (Fischer et al. 2023, Nutrition Reviews)

Adults and children across multiple trials.

Iron amino acid chelate supplementation raised hemoglobin and ferritin; Ferractiv is an iron amino acid chelate.

Side effects and drug interactions

Common Potential side effects

Can cause constipation, nausea, or stomach upset, though chelated iron is usually gentler.
May darken the stool, which is harmless.
Keep iron supplements away from children — overdose is dangerous.

Important Drug interactions

Levothyroxine, antibiotics (tetracyclines, quinolones) — iron reduces their absorption; separate by 2 to 4 hours.
Antacids, calcium — reduce iron absorption; separate dosing.
Do not take extra iron unless a blood test shows you need it.

Frequently asked questions about Ferractiv® (Iron Amino Acid Chelate — Biotron)

What is Ferractiv?

Ferractiv® is an iron amino acid chelate from Biotron Laboratories, designed to be gentler on the stomach than ferrous sulfate while remaining highly absorbable. As a chelated iron, it supports healthy iron levels, red blood cell formation, and the energy that depends on good iron status.

What is Ferractiv used for?

Ferractiv is researched primarily for Energy and Women's Health. Iron is essential for healthy red blood cells and oxygen transport; supplementing supports normal iron status and helps correct iron-deficiency anemia.

What is the recommended dosage of Ferractiv?

The clinically studied dose is Commonly providing the daily iron requirement (around 18 mg, or more if correcting a deficiency under medical guidance). Always follow the product label and check with a healthcare provider for personal advice.

Is Ferractiv safe, and does it have side effects?

For most healthy adults, Ferractiv is well tolerated at studied doses. Reported effects can include: Can cause constipation, nausea, or stomach upset, though chelated iron is usually gentler. May darken the stool, which is harmless. It may also interact with some medications. Ferractiv is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Ferractiv interact with any medications?

Possible interactions include: Levothyroxine, antibiotics (tetracyclines, quinolones) — iron reduces their absorption; separate by 2 to 4 hours. Antacids, calcium — reduce iron absorption; separate dosing. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Ferractiv?

NutraSmarts rates the evidence for Ferractiv as Strong (4 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Fischer JAJ, Cherian AM, Bone JN, Karakochuk CD. The effects of oral ferrous bisglycinate supplementation on hemoglobin and ferritin concentrations: a systematic review and meta-analysis. Nutr Rev. 2023;81(8):904-920..PubMedUsed to support: Meta-analysis supporting iron amino acid chelate for hemoglobin and ferritin (Ferractiv is an iron amino acid chelate).