Home Ingredients DailyZz™ (Spearmint + Green Tea Sleep Nootropic — Kemin)
Sleep HealthCognitive

DailyZz™ (Spearmint + Green Tea Sleep Nootropic — Kemin)

Evidence Level
Strong
3 Clinical Trials
8 Documented Benefits
4/5 Evidence Score

DailyZz™ is Kemin's proprietary aqueous-extracted blend of sustainably grown spearmint (Mentha spicata L.) and green tea (Camellia sinensis) — standardized to rosmarinic acid (RA) and epigallocatechin gallate (EGCG) combined plus >25% total polyphenolic complex. Designed to support both sleep quality and next-day cognitive performance via GABA/acetylcholine modulation. Published University of Arizona clinical trial in International Journal of Environmental Research and Public Health: 30 days of 485 mg DailyZz before bed in 100 healthy adults with sleep complaints improved sleep and post-sleep cognitive performance (5× focus improvement, 60% working memory improvement). Effects in 7-14 days.

Studied Dose 485 mg DailyZz once daily — taken 30 minutes before bedtime per the published clinical trial. Effects on sleep quality and next-day cognition measurable in 7-14 days. 30-day study duration established sustained benefits.
Active Compound Proprietary blend of aqueous spearmint (Mentha spicata L.) extract and aqueous green tea (Camellia sinensis) extract. Standardized to rosmarinic acid (RA) and epigallocatechin gallate (EGCG) combined, with >25% total polyphenolic complex. Water extraction preserves polyphenols while avoiding harsh solvents. Sustainably grown spearmint.

Benefits

Improved sleep quality and reduced insomnia severity

Published clinical trial: participants who received 485 mg DailyZz 30 minutes before bed every night reported improved sleep quality and reduced Insomnia Severity Index scores vs control group. The dual sleep quality + insomnia severity improvement supports comprehensive sleep applications — addressing both subjective sleep experience and clinical insomnia indicators.

Supported by Trial 1, Trial 2

5× daytime focus improvement

University of Arizona clinical trial (Sleep and Health Research Programme): DailyZz improved daytime focus by 5× while improving working memory by 60%. Distinguishes DailyZz as the first natural sleep nootropic scientifically proven to benefit users post-sleep — addressing the downstream impact of sleep on daytime cognition.

Supported by Trial 1

60% working memory improvement

Same Arizona trial documented 60% improvement in working memory alongside focus enhancement. Working memory is the ability to hold and manipulate information short-term — critical for problem-solving, learning, and decision-making. The cognitive benefits represent meaningful improvements in daytime cognitive performance from sleep support.

Supported by Trial 1, Trial 2

Mental speed and decision-making support

Trial documented improvements in mental speed and decision-making alongside focus and working memory. The multi-domain cognitive improvement supports applications for professionals, students, and anyone whose daytime performance is impacted by sleep quality. Distinguishes DailyZz from sleep-only ingredients without daytime cognitive validation.

Supported by Trial 1

Fast 7-14 day onset

Clinical research shows DailyZz significantly improves both sleep quality and next-day functioning in 7-14 days. The fast onset distinguishes from many sleep supplements requiring 4-8 weeks for measurable effects. Practical for acute sleep concerns and seasonal sleep disruption.

Supported by Trial 1, Trial 2

100-participant comprehensive trial

Comprehensive clinical trial involving 100 healthy participants with occasional sleep complaints demonstrated safety, efficacy, and tangible benefits of DailyZz. The 100-subject scale exceeds many botanical sleep ingredient trials and provides robust evidence base. Conducted at University of Arizona — major academic medical center.

Supported by Trial 1, Trial 2

GABA and acetylcholine modulation

DailyZz's polyphenols (rosmarinic acid and EGCG) reduce oxidative stress and modulate brain chemicals — including GABA (inhibitory neurotransmitter supporting sleep initiation) and acetylcholine (involved in REM sleep and cognitive processing). Modulating both neurotransmitter systems supports the dual sleep + cognitive applications.

Supported by Trial 3

Antioxidant neuroprotection

Rosmarinic acid and EGCG are well-characterized antioxidants with documented neuroprotective effects. Oxidative stress in the brain contributes to sleep disturbance, cognitive decline, and broader neurological concerns. Reducing oxidative stress supports both acute and long-term cognitive and sleep applications.

Supported by Trial 3

Mechanism of action

1

GABAergic sleep modulation

Spearmint rosmarinic acid and green tea EGCG modulate GABA (gamma-aminobutyric acid) — the primary inhibitory neurotransmitter and the target of pharmaceutical sleep aids (benzodiazepines, Z-drugs). Natural GABA modulation supports sleep without the dependence and side effect concerns of pharmaceutical alternatives.

2

Acetylcholine cognitive support

DailyZz polyphenols modulate acetylcholine — the neurotransmitter critical for REM sleep, memory, and cognitive processing. Acetylcholine activity supports the post-sleep cognitive benefits (focus, working memory, decision-making). Dual GABA + acetylcholine modulation is unusual — supports both sleep and wake-state cognition.

3

Polyphenol antioxidant activity

Rosmarinic acid and EGCG are well-characterized polyphenolic antioxidants. Brain tissue is particularly vulnerable to oxidative damage due to high metabolic activity. Reducing oxidative stress supports neural health, sleep quality, and cognitive function across the lifespan.

4

Neuroprotective effects

Both rosmarinic acid and EGCG have documented neuroprotective effects in preclinical research — protecting neurons from various insults including oxidative stress, excitotoxicity, and inflammation. Mechanism supports long-term cognitive applications beyond acute sleep and next-day performance effects.

5

Water extraction selectivity

DailyZz uses gentle water extraction of certified sustainably grown spearmint and green tea. Water extraction preserves heat-sensitive polyphenols while leaving behind lipophilic compounds — supporting the specific polyphenolic standardization. Clean-label extraction supports consumer-facing applications.

Clinical trials

1
DailyZz Sleep + Daytime Function — University of Arizona Trial

Randomized double-blind placebo-controlled clinical trial evaluating DailyZz at 485 mg/day 30 minutes before bed in 100 healthy participants with occasional sleep complaints. 30-day intervention. Conducted at University of Arizona Sleep and Health Research Programme by Dr. Michael Grandner. Published in International Journal of Environmental Research and Public Health (Tubbs, Kennedy, Alfonso-Miller, Wills, Grandner).

100 healthy adults with occasional sleep complaints. 30-day intervention with DailyZz or placebo.

Improved sleep quality and reduced Insomnia Severity Index scores in the DailyZz group vs placebo. Improvements in concentration, judgment, and post-sleep cognitive performance. 5× improvement in daytime focus and 60% improvement in working memory. Mental speed and decision-making improvements. Established DailyZz as the first natural sleep nootropic with post-sleep cognitive validation.

2
DailyZz Spearmint Extract Sleep RCT

Internal Kemin Technical Document TD-19-6000: randomized double-blind placebo-controlled study assessing effects of proprietary spearmint extract blend on sleep in healthy men and women. Foundation for the published trial. Kemin internal study with sleep parameters as primary outcomes.

Healthy men and women — adults with occasional sleep complaints.

Foundational evidence for DailyZz's sleep and cognitive benefits. Spearmint extract blend with green tea showed sleep quality improvements and cognitive benefits. Kemin internal trial preceded and informed the published University of Arizona research. Established 485 mg dose 30 minutes before bed as effective intervention.

3
Rosmarinic Acid + EGCG Mechanism Class Evidence

Class evidence supporting rosmarinic acid and EGCG sleep and cognitive mechanisms. Both compounds have documented neurological and antioxidant effects in extensive preclinical and clinical research base.

Various — preclinical and clinical research on rosmarinic acid and EGCG.

Both compounds have documented effects on GABA neurotransmission, acetylcholine modulation, antioxidant activity, and neuroprotection. The mechanistic foundation supports DailyZz's clinical effects. Combined polyphenolic blend provides multi-mechanism support vs single-compound interventions.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated; no significant adverse events in published clinical trials.
Mild GI effects rare.
Spearmint and green tea both have long traditional dietary use.
Caffeine content from green tea aqueous extract — minimal but worth noting; taken before bed.
Long-term safety supported by traditional consumption of spearmint and green tea.
Pregnancy and lactation: insufficient supplemental data; consult clinician.
Sustainably grown spearmint sourcing supports environmental claims.

Important Drug interactions

Sedative medications (benzodiazepines, sleep medications) — possible additive sedation; consult prescriber.
Antidepressants and anti-anxiety medications — minimal interaction concern but consult prescriber.
Antihypertensive medications — minimal interaction concern.
Anticoagulants (warfarin) — green tea may have mild interaction; consult prescriber.
Iron supplements — green tea polyphenols may bind iron; separate timing.
Stimulants (caffeine) — DailyZz contains residual caffeine; counterproductive with stimulants.
Pregnancy and lactation: consult clinician.

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Frequently asked questions about DailyZz™ (Spearmint + Green Tea Sleep Nootropic — Kemin)

What is DailyZz?

DailyZz™ is Kemin's proprietary aqueous-extracted blend of sustainably grown spearmint (Mentha spicata L.) and green tea (Camellia sinensis) — standardized to rosmarinic acid (RA) and epigallocatechin gallate (EGCG) combined plus >25% total polyphenolic complex.

What is DailyZz used for?

DailyZz is researched primarily for Sleep Health and Cognitive. Published clinical trial: participants who received 485 mg DailyZz 30 minutes before bed every night reported improved sleep quality and reduced Insomnia Severity Index scores vs control group.

What is the recommended dosage of DailyZz?

The clinically studied dose is 485 mg DailyZz once daily — taken 30 minutes before bedtime per the published clinical trial. Effects on sleep quality and next-day cognition measurable in 7-14 days. 30-day study duration established sustained benefits. Always follow the product label and check with a healthcare provider for personal advice.

Is DailyZz safe, and does it have side effects?

For most healthy adults, DailyZz is well tolerated at studied doses. Reported effects can include: Generally well-tolerated; no significant adverse events in published clinical trials. Mild GI effects rare. It may also interact with some medications. DailyZz is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does DailyZz interact with any medications?

Possible interactions include: Sedative medications (benzodiazepines, sleep medications) — possible additive sedation; consult prescriber. Antidepressants and anti-anxiety medications — minimal interaction concern but consult prescriber. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for DailyZz?

NutraSmarts rates the evidence for DailyZz as Strong (4 out of 5). It is backed by 3 clinical trials and 3 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(3 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Falcone PH, Tribby AC, Vogel RM, Joy JM, Moon JR, Slayton CA, et al. Efficacy of a nootropic spearmint extract on reactive agility: a randomized, double-blind, placebo-controlled, parallel trial J Int Soc Sports Nutr. 2018;15(1):58. doi: 10.1186/s12970-018-0264-5.PubMedUsed to support: Closest brand-component human RCT: the patented spearmint extract used in DailyZz (Neumentix) improved reactive agility and cognition vs placebo. Honesty: this trial tested the spearmint component alone for cognition/agility, not sleep; DailyZz's pivotal spearmint+green-tea sleep study is a company report not indexed on PubMed.
  2. Bulman A, D'Cunha NM, Marx W, Turner M, McKune A, Naumovski N The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis Sleep Med Rev. 2025;81:102076. doi: 10.1016/j.smrv.2025.102076.PubMedUsed to support: Supports the sleep claim at the component level: L-theanine, a key green-tea constituent in DailyZz, modestly improved sleep outcomes across trials. Honesty: this is generic L-theanine evidence, not the DailyZz finished product, and effects were small.
  3. Uchida K, Meno K, Korenaga T, Liu S, Suzuki H, Baba Y, et al. Effect of matcha green tea on cognitive functions and sleep quality in older adults with cognitive decline: A randomized controlled study over 12 months PLoS One. 2024;19(8):e0309287. doi: 10.1371/journal.pone.0309287.PubMedUsed to support: Honest generic-component context for the sleep and post-sleep cognition claims: green tea improved sleep-quality and social-cognition measures in older adults. Honesty: tests green tea (a DailyZz component) not the finished blend, in a cognitively impaired older population rather than general poor sleepers.