Home Ingredients DailyZz™ (Spearmint + Green Tea Sleep Nootropic — Kemin)
Sleep HealthCognitive

DailyZz™ (Spearmint + Green Tea Sleep Nootropic — Kemin)

Evidence Level
Limited
1 Clinical Trial
4 Documented Benefits
2/5 Evidence Score

DailyZz is Kemin's proprietary aqueous-extracted blend of sustainably grown spearmint (Mentha spicata L.) and green tea (Camellia sinensis), standardized to rosmarinic acid (RA) and epigallocatechin gallate (EGCG) combined plus >25% total polyphenolic complex. Designed to support both sleep quality and next-day cognitive performance via GABA/acetylcholine modulation. In healthy adults with sleep complaints, 485 mg DailyZz before bed improved diary sleep quality (p=0.008) and reduced insomnia severity (p=0.044) over a 30-day trial, with only qualitative next-day improvement in vigilant attention, working memory, and risk assessment (no fold- or percentage-change figures reported).

Studied Dose 485 mg once daily.
Active Compound Aqueous spearmint (Mentha spicata L.) + green tea (Camellia sinensis) extract; standardized to rosmarinic acid + EGCG, >25% total polyphenols.

Benefits

Supports sleep quality

Participants taking 485 mg DailyZz before bed reported improved sleep quality and reduced Insomnia Severity Index scores vs control. The dual sleep quality + insomnia severity improvement supports comprehensive sleep applications, addressing both subjective sleep experience and clinical insomnia indicators.

Supported by Trial 1

Mental speed and decision-making support

In the Tubbs 2021 trial, the DailyZz group showed only qualitative "some improvement" in vigilant attention, working memory, and risk assessment, with no neurocognitive impairment. These next-day cognitive signals were descriptive and were not quantified.

Supported by Trial 1

GABA and acetylcholine modulation

DailyZz's polyphenols (rosmarinic acid and EGCG) reduce oxidative stress and modulate brain chemicals — including GABA (inhibitory neurotransmitter supporting sleep initiation) and acetylcholine (involved in REM sleep and cognitive processing). Modulating both neurotransmitter systems supports the dual sleep + cognitive applications.

Supported by Trial 1

Antioxidant neuroprotection

Rosmarinic acid and EGCG are well-characterized antioxidants with documented neuroprotective effects. Oxidative stress in the brain contributes to sleep disturbance, cognitive decline, and broader neurological concerns. Reducing oxidative stress supports both acute and long-term cognitive and sleep applications.

Supported by Trial 1

Mechanism of action

1

GABAergic sleep modulation

Spearmint rosmarinic acid and green tea EGCG modulate GABA (gamma-aminobutyric acid) — the primary inhibitory neurotransmitter and the target of pharmaceutical sleep aids (benzodiazepines, Z-drugs). Natural GABA modulation supports sleep without the dependence and side effect concerns of pharmaceutical alternatives.

2

Acetylcholine cognitive support

DailyZz polyphenols modulate acetylcholine — the neurotransmitter critical for REM sleep, memory, and cognitive processing. Acetylcholine activity supports the post-sleep cognitive benefits (focus, working memory, decision-making). Dual GABA + acetylcholine modulation is unusual — supports both sleep and wake-state cognition.

3

Polyphenol antioxidant activity

Rosmarinic acid and EGCG are well-characterized polyphenolic antioxidants. Brain tissue is particularly vulnerable to oxidative damage due to high metabolic activity. Reducing oxidative stress supports neural health, sleep quality, and cognitive function across the lifespan.

4

Neuroprotective effects

Both rosmarinic acid and EGCG have documented neuroprotective effects in preclinical research — protecting neurons from various insults including oxidative stress, excitotoxicity, and inflammation. Mechanism supports long-term cognitive applications beyond acute sleep and next-day performance effects.

5

Water extraction selectivity

DailyZz uses gentle water extraction of certified sustainably grown spearmint and green tea. Water extraction preserves heat-sensitive polyphenols while leaving behind lipophilic compounds — supporting the specific polyphenolic standardization. Clean-label extraction supports consumer-facing applications.

Clinical trials

1
DailyZz Sleep + Daytime Function — University of Arizona Trial
PubMed

Randomized double-blind placebo-controlled clinical trial evaluating DailyZz at 485 mg/day 30 minutes before bed in adults with occasional sleep complaints (n=89 completers). 30-day intervention. Conducted at University of Arizona Sleep and Health Research Programme by Dr. Michael Grandner. Published in International Journal of Environmental Research and Public Health (Tubbs, Kennedy, Alfonso-Miller, Wills, Grandner).

89 completers (healthy adults with occasional sleep complaints). 30-day intervention with DailyZz or placebo.

Improved diary sleep quality (p=0.008) and reduced insomnia severity (p=0.044) in the DailyZz group vs placebo, with no neurocognitive impairment. Cognitive endpoints showed only qualitative "some improvement in vigilant attention, working memory, and risk assessment" — no fold- or percentage-change figures were reported.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated; no significant adverse events in published clinical trials.
Mild GI effects rare.
Spearmint and green tea both have long traditional dietary use.
Caffeine content from green tea aqueous extract — minimal but worth noting; taken before bed.
Long-term safety supported by traditional consumption of spearmint and green tea.
Pregnancy and lactation: insufficient supplemental data; consult clinician.
Sustainably grown spearmint sourcing supports environmental claims.

Important Drug interactions

Sedative medications (benzodiazepines, sleep medications) — possible additive sedation; consult prescriber.
Antidepressants and anti-anxiety medications — minimal interaction concern but consult prescriber.
Antihypertensive medications — minimal interaction concern.
Anticoagulants (warfarin) — green tea may have mild interaction; consult prescriber.
Iron supplements — green tea polyphenols may bind iron; separate timing.
Stimulants (caffeine) — DailyZz contains residual caffeine; counterproductive with stimulants.
Pregnancy and lactation: consult clinician.

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Frequently asked questions about DailyZz™ (Spearmint + Green Tea Sleep Nootropic — Kemin)

What is DailyZz?

DailyZz is Kemin's proprietary aqueous-extracted blend of sustainably grown spearmint (Mentha spicata L.) and green tea (Camellia sinensis), standardized to rosmarinic acid (RA) and epigallocatechin gallate (EGCG) combined plus >25% total polyphenolic complex.

What is DailyZz used for?

DailyZz is researched primarily for Sleep Health and Cognitive. Participants taking 485 mg DailyZz before bed reported improved sleep quality and reduced Insomnia Severity Index scores vs control.

What is the recommended dosage of DailyZz?

The clinically studied dose is 485 mg once daily. Always follow the product label and check with a healthcare provider for personal advice.

Is DailyZz safe, and does it have side effects?

For most healthy adults, DailyZz is well tolerated at studied doses. Reported effects can include: Generally well-tolerated; no significant adverse events in published clinical trials. Mild GI effects rare. It may also interact with some medications. DailyZz is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does DailyZz interact with any medications?

Possible interactions include: Sedative medications (benzodiazepines, sleep medications) — possible additive sedation; consult prescriber. Antidepressants and anti-anxiety medications — minimal interaction concern but consult prescriber. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for DailyZz?

NutraSmarts rates the evidence for DailyZz as Limited (2 out of 5). It is backed by 1 clinical trial and 4 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(4 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Tubbs AS, Kennedy KER, Alfonso-Miller P, Wills CCA, Grandner MA A Randomized, Double-Blind, Placebo-Controlled Trial of a Polyphenol Botanical Blend on Sleep and Daytime Functioning Int J Environ Res Public Health. 2021;18(6):3044. doi: 10.3390/ijerph18063044.PubMedUsed to support: The pivotal finished-product RCT of DailyZz (RA+EGCG polyphenol blend, 485 mg, n=89 completers, 30 days): improved diary sleep quality (p=0.008) and reduced insomnia severity (p=0.044) vs placebo, with only qualitative next-day cognitive improvement and no neurocognitive impairment.
  2. Falcone PH, Tribby AC, Vogel RM, Joy JM, Moon JR, Slayton CA, et al. Efficacy of a nootropic spearmint extract on reactive agility: a randomized, double-blind, placebo-controlled, parallel trial J Int Soc Sports Nutr. 2018;15(1):58. doi: 10.1186/s12970-018-0264-5.PubMedUsed to support: Closest brand-component human RCT: the patented spearmint extract used in DailyZz (Neumentix) improved reactive agility and cognition vs placebo. Honesty: this trial tested the spearmint component alone for cognition/agility, not sleep; DailyZz's pivotal spearmint+green-tea sleep study (Tubbs 2021, PMID 33809544) is published in Int J Environ Res Public Health and is PubMed-indexed.
  3. Bulman A, D'Cunha NM, Marx W, Turner M, McKune A, Naumovski N The effects of L-theanine consumption on sleep outcomes: A systematic review and meta-analysis Sleep Med Rev. 2025;81:102076. doi: 10.1016/j.smrv.2025.102076.PubMedUsed to support: Supports the sleep claim at the component level: L-theanine, a key green-tea constituent in DailyZz, modestly improved sleep outcomes across trials. Honesty: this is generic L-theanine evidence, not the DailyZz finished product, and effects were small.
  4. Uchida K, Meno K, Korenaga T, Liu S, Suzuki H, Baba Y, et al. Effect of matcha green tea on cognitive functions and sleep quality in older adults with cognitive decline: A randomized controlled study over 12 months PLoS One. 2024;19(8):e0309287. doi: 10.1371/journal.pone.0309287.PubMedUsed to support: Honest generic-component context for the sleep and post-sleep cognition claims: green tea improved sleep-quality and social-cognition measures in older adults. Honesty: tests green tea (a DailyZz component) not the finished blend, in a cognitively impaired older population rather than general poor sleepers.