Home Ingredients Cratavin® (Crataeva nurvala for Urinary Health — Sabinsa)
Kidney/Urinary Tract

Cratavin® (Crataeva nurvala for Urinary Health — Sabinsa)

Crataeva nurvala
Evidence Level
Limited
0 Clinical Trials
3 Documented Benefits
2/5 Evidence Score

Cratavin is a standardized extract of Crataeva nurvala (varuna) bark from Sabinsa, a botanical traditionally used in Ayurveda to support urinary-tract and bladder health. The bark supplies lupeol and related triterpenes, and the ingredient is positioned to support healthy bladder tone and normal urinary flow. Direct published clinical data on the Cratavin extract itself are limited. The closest human research is a maker-funded trial of a multi-herb formula built around a different branded Crataeva extract, which reported improvements in everyday bladder symptoms; animal studies add mechanistic support for a healthy urinary mineral balance. For now, most of the support for Cratavin specifically rests on traditional use and supplier research rather than independent trials of the branded extract.

Studied Dose Per the product specification.
Active Compound Crataeva nurvala bark extract (standardized for lupeol and related triterpenes).

Benefits

Urinary-tract support

Crataeva nurvala is traditionally used to support a healthy urinary tract and bladder, the basis for Cratavin's positioning.

Bladder tone and flow

The extract is positioned to support healthy bladder muscle tone and normal urinary flow.

Evidence basis

Support comes mainly from traditional use and supplier research; dedicated published clinical data for the specific extract are limited.

Mechanism of action

1

Bladder-tone support

Crataeva constituents such as lupeol are studied for supporting the tone of the bladder's detrusor muscle and normal bladder emptying.

2

Studied urinary-tract properties

The triterpenes are studied for supporting a calm urinary tract and supporting a healthy urinary mineral balance in preclinical (animal) research.

Clinical trials

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Mild digestive upset is occasionally reported.
See a doctor for urinary pain, blood in urine, or fever.

Important Drug interactions

No major drug interactions are established for this extract.
Tell your doctor about persistent urinary symptoms.
Use caution if pregnant, breastfeeding, or managing a condition.

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Frequently asked questions about Cratavin® (Crataeva nurvala for Urinary Health — Sabinsa)

What is Cratavin?

Cratavin is a standardized extract of Crataeva nurvala (varuna) bark from Sabinsa, a botanical traditionally used in Ayurveda to support urinary-tract and bladder health. The bark supplies lupeol and related triterpenes, and the ingredient is positioned to support healthy bladder tone and normal urinary flow.

What is Cratavin used for?

Cratavin is researched primarily for Kidney/Urinary Tract. Crataeva nurvala is traditionally used to support a healthy urinary tract and bladder, the basis for Cratavin's positioning.

What is the recommended dosage of Cratavin?

The clinically studied dose is Per the product specification. Always follow the product label and check with a healthcare provider for personal advice.

Is Cratavin safe, and does it have side effects?

Side effects and cautions reported for Cratavin include: Generally well-tolerated. Mild digestive upset is occasionally reported. It may also interact with some medications. Cratavin is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Cratavin interact with any medications?

Possible interactions include: No major drug interactions are established for this extract. Tell your doctor about persistent urinary symptoms. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Cratavin?

NutraSmarts rates the evidence for Cratavin as Limited (2 out of 5). It is backed by 2 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(2 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Schoendorfer N, Sharp N, Seipel T, Schauss AG, Ahuja KDK Urox containing concentrated extracts of Crataeva nurvala stem bark, Equisetum arvense stem and Lindera aggregata root, in the treatment of symptoms of overactive bladder and urinary incontinence: a phase 2, randomised, double-blind placebo controlled trial BMC Complementary and Alternative Medicine. 2018;18(1):42. doi:10.1186/s12906-018-2101-4.PubMedUsed to support: Phase 2 human RCT of the Urox three-herb formula (built around the Cratevox-branded Crataeva nurvala extract, not Sabinsa's Cratavin) that significantly reduced urinary frequency (7.69 vs 10.95 voids/day), urgency, nocturia, and incontinence vs placebo at 8 weeks, with improved quality of life; the trial was funded by the formula's maker (Seipel Group) and a study author holds the formulation patent; supports the general urinary-tract and bladder-tone use of Crataeva nurvala, but Cratavin itself was not tested in isolation
  2. Agarwal S, Gupta SJ, Saxena AK, Gupta N, Agarwal S Urolithic property of Varuna (Crataeva nurvala): An experimental study Ayu. 2010;31(3):361-6. doi:10.4103/0974-8520.77161.PubMedUsed to support: Animal (rat) experimental study demonstrating Crataeva nurvala decoction supports urinary tract health by regulating metabolic factors associated with urolithiasis; mechanistic basis for Urinary-tract support benefit of Cratavin's active ingredient (animal study; Cratavin brand not independently tested in published human clinical trial)