Centevita® (Centella asiatica Extract — Indena)

Centella asiatica
Evidence Level
Limited
1 Clinical Trial
3 Documented Benefits
2/5 Evidence Score

Centevita® is a standardized Centella asiatica (gotu kola) leaf extract from Indena. Centella is a traditional herb valued for supporting microcirculation, connective tissue, and cognition, and Centevita is a characterized extract delivering its active triterpenes and polyphenols.

Studied Dose Commonly 60 to 120 mg of standardized extract per day.
Active Compound Centella asiatica leaf extract standardized for triterpenes (such as asiaticoside and madecassoside) and polyphenols.

Benefits

Microcirculation and veins

Centella asiatica is traditionally used to support microcirculation and the tone of veins, relevant to leg heaviness and vascular comfort.

Connective tissue and skin

Its triterpenes support collagen formation and wound healing, underpinning its use for skin firmness and connective-tissue health.

Cognitive and calm support

Centella has a long history of use for mental clarity and a calm, focused state, supported by its antioxidant triterpenes.

Mechanism of action

1

Triterpene collagen support

Asiaticoside and madecassoside stimulate collagen synthesis and support the strength of connective tissue and blood-vessel walls.

2

Antioxidant protection

Centella polyphenols counter oxidative stress in vascular and nervous tissue, contributing to its circulatory and cognitive uses.

Clinical trials

1
Centevita Centella Extract — Characterization Study
PubMed

Phytochemical characterization of the standardized Centella asiatica extract Centevita. (Masi et al. 2022, Fitoterapia)

Laboratory characterization.

The study defined the triterpene and polyphenol profile of the standardized extract, confirming the actives behind Centella's traditional circulatory and connective-tissue uses. Human efficacy data for the specific extract are limited.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — Centella is well tolerated at normal doses.
Mild digestive upset or drowsiness is occasionally reported.
Avoid in pregnancy due to limited data.

Important Drug interactions

Sedatives — possible additive calming effect.
Diabetes or cholesterol drugs — monitor, as Centella may affect these.
Liver-affecting drugs — use caution with prolonged high doses.

Frequently asked questions about Centevita® (Centella asiatica Extract — Indena)

What is Centevita?

Centevita® is a standardized Centella asiatica (gotu kola) leaf extract from Indena. Centella is a traditional herb valued for supporting microcirculation, connective tissue, and cognition, and Centevita is a characterized extract delivering its active triterpenes and polyphenols.

What is Centevita used for?

Centevita is researched primarily for Cognitive and Hair, Skin & Nails. Centella asiatica is traditionally used to support microcirculation and the tone of veins, relevant to leg heaviness and vascular comfort.

What is the recommended dosage of Centevita?

The clinically studied dose is Commonly 60 to 120 mg of standardized extract per day. Always follow the product label and check with a healthcare provider for personal advice.

Is Centevita safe, and does it have side effects?

For most healthy adults, Centevita is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — Centella is well tolerated at normal doses. Mild digestive upset or drowsiness is occasionally reported. It may also interact with some medications. Centevita is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Centevita interact with any medications?

Possible interactions include: Sedatives — possible additive calming effect. Diabetes or cholesterol drugs — monitor, as Centella may affect these. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Centevita?

NutraSmarts rates the evidence for Centevita as Limited (2 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Masi F, Chianese G, Peterlongo F, et al. Phytochemical profile of Centevita, a Centella asiatica leaves extract. Fitoterapia. 2022;158:105163..PubMedUsed to support: Characterization of the standardized Centella extract.