Cauliflower (Brassica oleracea var. botrytis)

Brassica oleracea var. botrytis
Evidence Level
Preliminary
4 Clinical Trials
6 Documented Benefits
1/5 Evidence Score

Cauliflower (Brassica oleracea var. botrytis) is a cruciferous vegetable eaten raw, cooked, or chopped fine as riced cauliflower. Per 100 g raw, it supplies about 48 mg of vitamin C, 2 g of fiber and 15.5 micrograms of vitamin K for 25 kcal (USDA). It contains glucosinolates, mainly sinigrin, which can be converted to isothiocyanates; in lab tests, boiling leached glucosinolates into the cooking water. Human research on cauliflower by itself is sparse: one single-meal test found a lower glycemic index when cooked cauliflower was eaten with rice than for rice alone (not when the cauliflower was pureed), and longer feeding trials used blends led by broccoli. Riced cauliflower has far fewer carbohydrates and calories than cooked white rice, a nutrient difference, not a tested health effect. Like other crucifers it can cause gas, and people on warfarin should keep their vitamin K intake steady.

Studied Dose 300 g of cooked cauliflower with a rice meal (100 g first, 200 g with the rice) in single test meals; six 84 g portions over 2 weeks within a high-Brassica diet led by broccoli; about 300 g a day of a crucifer soup (25% cauliflower) for 2 weeks.
Active Compound Whole cauliflower florets (Brassica oleracea var. botrytis), eaten raw, cooked or riced. Supplies glucosinolates (mainly sinigrin, plus glucobrassicin), vitamin C, fiber and a small amount of vitamin K.

Benefits

A source of vitamin C and fiber

Per 100 g raw, cauliflower supplies about 48 mg of vitamin C, 2 g of dietary fiber and 57 micrograms of folate for 25 kcal, according to USDA data. Boiled, drained cauliflower is listed at about 44 mg of vitamin C per 100 g. These figures describe nutrient content, not a tested health effect.

Fewer carbohydrates and calories than cooked white rice

Per 100 g, raw cauliflower has about 5 g of carbohydrate, 2 g of fiber and 25 kcal, while cooked white rice has about 28 g of carbohydrate, 0.4 g of fiber and 130 kcal, according to USDA data. This is why riced cauliflower is used in place of rice. It is a nutrient comparison, not a tested health outcome.

Post-meal blood glucose when cooked cauliflower was eaten with rice

In a randomized crossover test of single meals in 16 healthy young women, rice eaten with 300 g of cooked cauliflower had a glycemic index of 73, significantly lower than rice alone. When the cauliflower was pureed first, the difference from rice disappeared, and pak choi and eggplant gave similar or lower values. This was one meal at a time, not long-term blood sugar control.

Blood pressure and glucose in a crucifer soup trial (25% cauliflower)

In a 2-week crossover trial of 18 older adults with mildly raised blood pressure, crucifer soups (40% broccoli, 25% cauliflower) lowered 24-hour systolic pressure by 2.5 mmHg and post-meal glucose slightly versus root and squash soups. Average glucose did not differ, and cauliflower was not tested alone.

Gut bacteria on a high-Brassica diet that included cauliflower

In a crossover trial of 10 healthy adults, 2 weeks of a high-Brassica diet (broccoli, broccoli soup and cauliflower) lowered the share of sulfate-reducing gut bacteria compared with a low-Brassica diet, while lactobacilli did not change. Cauliflower was one part of the diet, and gut symptoms were not an outcome.

Glucosinolates and isothiocyanates from cauliflower

In a survey of Brassica crops, cauliflower's main glucosinolates were sinigrin and glucobrassicin. After two volunteers ate broccoli and cauliflower, breakdown products of sulforaphane and allyl isothiocyanate appeared in their urine. In lab tests of Brassica vegetables including cauliflower, boiling, but not steaming or microwaving, leached them into the water.

Mechanism of action

1

Glucosinolates and isothiocyanates

Cauliflower contains glucosinolates, mainly sinigrin, which the plant enzyme myrosinase turns into allyl isothiocyanate; in lab tests, finely shredded Brassica vegetables lost glucosinolates partly as isothiocyanates. In a human study of cabbage, a variety of the same species, cooking lowered and delayed this, with colon bacteria apparently taking over. Sulforaphane forms from a different glucosinolate, glucoraphanin, covered on our sulforaphane page.

2

Glutathione conjugation and urinary excretion

Isothiocyanates are absorbed, joined to glutathione and excreted in urine as mercapturic acids. A method study measured sulforaphane and allyl isothiocyanate mercapturic acids in 24-hour urine from two volunteers after a broccoli and cauliflower meal.

3

Intact vegetable texture and starch digestion

In lab digestion tests, a meal of rice and cooked cauliflower released starch more slowly (80.6% of the rate for rice alone). Blending removed the effect on blood glucose in volunteers, so the authors pointed to the physical texture of the vegetable rather than a specific compound.

4

Induction of drug-metabolizing enzymes

A meta-analysis of diet trials with broccoli, Brussels sprouts, cabbage, cauliflower, radish and watercress found that crucifer-enriched diets raised CYP1A2 activity by 20 to 40% and glutathione S-transferase alpha by 15 to 35%. Cauliflower was not studied alone.

Clinical trials

1
Cooked Cauliflower With Rice and Post-Meal Glucose: Crossover Test Meals
PubMed

Randomized crossover glycemic response study: 13 test sessions per person, comparing rice alone and glucose with rice eaten with 300 g of pak choi, cauliflower or eggplant (100 g first, 200 g with the rice), whole or homogenized, raw or cooked; plus in vitro starch digestion. (Zhu et al. 2018, Br J Nutr)

16 healthy young women (aged 18 to 24, BMI 20 to 24.9) in China.

Rice with whole cooked cauliflower had a glycemic index of 73, significantly lower than rice alone; homogenized versions did not differ from rice. In vitro starch hydrolysis was 80.6% of rice. Eggplant had the largest effect. Single meals in young women only. No specific grant funding; no conflicts declared.

2
High vs Low Brassica Diet and Gut Bacteria: 10-Adult Crossover
PubMed

Randomized crossover trial of a high-Brassica diet (six 84 g portions each of broccoli and cauliflower plus six 300 g broccoli and sweet potato soups over 2 weeks) versus a low-Brassica diet (one portion each), with 2-week Brassica-free washouts. (Kellingray et al. 2017, Mol Nutr Food Res)

10 healthy adults in the UK.

Lactobacilli did not change (p = 0.80). The high-Brassica diet lowered the relative abundance of sulfate-reducing bacteria (p = 0.02) and several other groups. No adverse effects were reported. Broccoli was the lead vegetable. Funded by public research councils; no conflicts declared.

3
Crucifer Soups (25% Cauliflower) and Blood Pressure: VESSEL Crossover RCT
PubMed

Randomized controlled crossover trial, participants not told which soup was active: about 300 g a day of cruciferous vegetables (40% broccoli, 25% cauliflower, 25% cabbage, 10% kale) versus root and squash vegetables, 2 weeks each with a 2-week washout. (Connolly et al. 2024, BMC Med)

18 adults (median age 68, 16 women) in Australia with systolic blood pressure of 120 to 160 mmHg.

24-hour systolic pressure fell 2.5 mmHg more than with the control soup (P = 0.002), and triglycerides 0.2 mmol/L more (P = 0.047). Nighttime aortic diastolic pressure was 2.9 mmHg higher with the crucifer soup (P = 0.014). No adverse events. Funded by university and state health department grants. A small, short trial of a blend, not cauliflower alone.

4
Crucifer Soups (25% Cauliflower) and Glucose: VESSEL Secondary Outcome
PubMed

Prespecified secondary analysis of the VESSEL crossover trial, with flash glucose monitoring every 15 minutes during both 2-week soup periods. (Connolly et al. 2025, Diabetes Obes Metab)

18 adults without diabetes (89% women, median age 68) with raised blood pressure.

Glucose variability was 2.0% lower and the 2-hour post-meal glucose response 0.14 mmol/L lower with the crucifer soups, driven by dinner. Mean glucose did not differ (p = 0.41). The authors called the clinical impact uncertain. Cauliflower was one of four vegetables.

Side effects and drug interactions

Common Potential side effects

Cruciferous vegetables, including cauliflower, contain carbohydrates that are not fully digested and are broken down by colon bacteria, which can cause gas and bloating in some people.
No adverse effects were reported in the high-Brassica diet trial (10 adults) or the crucifer soup trial (18 adults), but these were small and short.
Cauliflower supplies only a small amount of vitamin K (about 15.5 micrograms per 100 g raw), much less than kale or cabbage; see the warfarin note below.
Cruciferous vegetables such as cauliflower contain goitrogens, which matter mainly with low iodine intake; a systematic review found no adverse thyroid effects of Brassica vegetables in the diet with adequate iodine.

Important Drug interactions

Warfarin and other vitamin K antagonists: cauliflower contains some vitamin K, and sudden changes in vitamin K intake can raise or lower the anticoagulant effect. Keep your intake steady from day to day and tell your anticoagulation clinic about large diet changes.
Drugs cleared by CYP1A2: in a meta-analysis of diet trials, crucifer-enriched diets raised CYP1A2 activity by 20 to 40%. If you take such a drug, avoid large, sudden changes in how much crucifer vegetable you eat and ask your pharmacist.
Thyroid medication: Brassica vegetables in normal diets with adequate iodine did not harm thyroid function in a systematic review, but people treated for thyroid conditions can ask their doctor about very large raw intakes.

Frequently asked questions about Cauliflower (Brassica oleracea var. botrytis)

Is riced cauliflower lower in carbohydrates than white rice?

Yes, by a wide margin. USDA data list about 5 g of carbohydrate, 2 g of fiber and 25 kcal per 100 g of raw cauliflower, versus about 28 g of carbohydrate, 0.4 g of fiber and 130 kcal per 100 g of cooked white rice. That is a difference in nutrient content; swapping one for the other has not been tested as a health intervention in trials.

Has cauliflower by itself been tested in human trials?

Barely. One single-meal study in 16 young women found a lower glycemic index when cooked cauliflower was eaten with rice than for rice alone, but only when the cauliflower was not pureed. Longer feeding trials used crucifer mixes led by broccoli, so their results cannot be credited to cauliflower.

Does cooking cauliflower change its glucosinolates?

Boiling does the most damage: in lab tests, boiling caused significant glucosinolate losses, mostly into the cooking water, while steaming, microwaving and stir frying did not. In a human study of cabbage, a close relative, microwaved cabbage released considerably less isothiocyanate, and later, than raw cabbage, even though microwaving did not destroy the glucosinolates themselves in the lab tests.

Why does cauliflower give me gas?

Like other cruciferous vegetables, cauliflower contains carbohydrates that the small intestine does not fully digest. Bacteria in the large intestine ferment them and produce gas. NIDDK lists cauliflower among foods that may lead to excess gas and suggests talking with a doctor or dietitian about an eating plan if gas is a problem.

Is cauliflower safe if I take warfarin?

Usually, if your intake stays steady. Cauliflower is fairly low in vitamin K (about 15.5 micrograms per 100 g raw, compared with an Adequate Intake of 90 to 120 micrograms a day), but sudden large changes in any vitamin K source can affect warfarin. Keep your usual amount steady and tell your anticoagulation clinic about big diet changes.

What is Cauliflower?

Cauliflower (Brassica oleracea var. botrytis) is a cruciferous vegetable eaten raw, cooked, or chopped fine as riced cauliflower. Per 100 g raw, it supplies about 48 mg of vitamin C, 2 g of fiber and 15.5 micrograms of vitamin K for 25 kcal (USDA).

What is Cauliflower used for?

Cauliflower is researched primarily for Metabolic Health. Per 100 g raw, cauliflower supplies about 48 mg of vitamin C, 2 g of dietary fiber and 57 micrograms of folate for 25 kcal, according to USDA data. Boiled, drained cauliflower is listed at about 44 mg of vitamin C per 100 g.

What is the recommended dosage of Cauliflower?

The clinically studied dose is 300 g of cooked cauliflower with a rice meal (100 g first, 200 g with the rice) in single test meals; six 84 g portions over 2 weeks within a high-Brassica diet led by broccoli; about 300 g a day of a crucifer soup (25% cauliflower) for 2 weeks. Always follow the product label and check with a healthcare provider for personal advice.

Does Cauliflower interact with any medications?

Possible interactions include: Warfarin and other vitamin K antagonists: cauliflower contains some vitamin K, and sudden changes in vitamin K intake can raise or lower the anticoagulant effect. Keep your intake steady from day to day and tell your anticoagulation clinic about large diet changes. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Cauliflower?

NutraSmarts rates the evidence for Cauliflower as Preliminary (1 out of 5). It is backed by 4 study summaries and 16 cited references summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(16 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. U.S. Department of Agriculture, Agricultural Research Service. Cauliflower, raw. FoodData Central, SR Legacy (FDC ID 169986). USDA FoodData Central. 2019;FDC ID 169986, per 100 g: vitamin C 48.2 mg; vitamin K (phylloquinone) 15.5 micrograms; folate 57 micrograms; fiber 2.0 g; carbohydrate 4.97 g; energy 25 kcal..SourceUsed to support: Official U.S. nutrient database entry (not PubMed-indexed). Per 100 g of raw cauliflower: vitamin C 48.2 mg, vitamin K 15.5 micrograms, folate 57 micrograms, dietary fiber 2.0 g, carbohydrate 4.97 g and 25 kcal. Basis for the raw cauliflower nutrient figures.
  2. U.S. Department of Agriculture, Agricultural Research Service. Cauliflower, cooked, boiled, drained, without salt. FoodData Central, SR Legacy (FDC ID 170397). USDA FoodData Central. 2019;FDC ID 170397, per 100 g: vitamin C 44.3 mg; vitamin K (phylloquinone) 13.8 micrograms; fiber 2.3 g; carbohydrate 4.11 g; energy 23 kcal..SourceUsed to support: Official U.S. nutrient database entry (not PubMed-indexed). Per 100 g of boiled, drained cauliflower: vitamin C 44.3 mg, vitamin K 13.8 micrograms, dietary fiber 2.3 g, carbohydrate 4.11 g and 23 kcal. Basis for the cooked cauliflower figures.
  3. U.S. Department of Agriculture, Agricultural Research Service. Rice, white, long-grain, regular, enriched, cooked. FoodData Central, SR Legacy (FDC ID 168878). USDA FoodData Central. 2019;FDC ID 168878, per 100 g: carbohydrate 28.2 g; fiber 0.4 g; energy 130 kcal..SourceUsed to support: Official U.S. nutrient database entry (not PubMed-indexed). Per 100 g of cooked enriched long-grain white rice: carbohydrate 28.2 g, dietary fiber 0.4 g and 130 kcal. Basis for the nutrient comparison between riced cauliflower and white rice.
  4. Kushad MM, Brown AF, Kurilich AC, Juvik JA, Klein BP, Wallig MA, Jeffery EH. Variation of glucosinolates in vegetable crops of Brassica oleracea. J Agric Food Chem. 1999;47(4):1541-8. doi: 10.1021/jf980985s.PubMedUsed to support: Analysis of glucosinolates in 65 accessions of 5 Brassica oleracea crop groups grown under the same conditions: in cauliflower the predominant glucosinolates were sinigrin (9.3 micromol/g dry weight) and glucobrassicin (1.3 micromol/g dry weight), with wide variation among genotypes.
  5. Song L, Thornalley PJ. Effect of storage, processing and cooking on glucosinolate content of Brassica vegetables. Food Chem Toxicol. 2007;45(2):216-24. doi: 10.1016/j.fct.2006.07.021.PubMedUsed to support: Laboratory study of 7 major glucosinolates in broccoli, Brussels sprouts, cauliflower and green cabbage: storage caused little loss, fine shredding caused up to 75% decline over 6 hours, and steaming, microwaving and stir frying did not cause significant loss, whereas boiling caused significant losses, about 90% of which was found in the cooking water.
  6. Rouzaud G, Young SA, Duncan AJ. Hydrolysis of glucosinolates to isothiocyanates after ingestion of raw or microwaved cabbage by human volunteers. Cancer Epidemiol Biomarkers Prev. 2004;13(1):125-31. doi: 10.1158/1055-9965.epi-085-3.PubMedUsed to support: Crossover study in 12 healthy volunteers eating cabbage, a variety of the same species as cauliflower: the glucosinolate sinigrin is hydrolyzed by myrosinase to allyl isothiocyanate. Excretion was rapid after raw cabbage and considerably lower and delayed after cooked cabbage, which the authors attributed to colon bacteria. Cited for the general glucosinolate pathway, not for cauliflower itself.
  7. Vermeulen M, van Rooijen HJ, Vaes WH. Analysis of isothiocyanate mercapturic acids in urine: a biomarker for cruciferous vegetable intake. J Agric Food Chem. 2003;51(12):3554-9. doi: 10.1021/jf0341316.PubMedUsed to support: Method paper: glucosinolates from cruciferous vegetables are degraded to isothiocyanates, which are absorbed, conjugated to glutathione and excreted in urine as mercapturic acids. In 24-hour urine from two volunteers after they ate broccoli and cauliflower, sulforaphane mercapturic acid (133 micromol) and allyl isothiocyanate mercapturic acid (4.7 micromol) were found.
  8. Zhu R, Liu M, Han Y, Wang L, Ye T, Lu J, Fan Z. Acute effects of non-homogenised and homogenised vegetables added to rice-based meals on postprandial glycaemic responses and in vitro carbohydrate digestion. Br J Nutr. 2018;120(9):1023-1033. doi: 10.1017/S0007114518002489.PubMedUsed to support: Randomized crossover study in 16 healthy women aged 18 to 24 (13 test sessions each): rice eaten with 300 g of whole cooked cauliflower had a glycemic index of 73, significantly lower than rice alone, as did rice with pak choi (71) and eggplant (67), while homogenized versions did not differ from rice. In vitro starch hydrolysis for the cauliflower meal was 80.6% of rice. Only the vegetable was homogenized for the meal tests. The authors suggested vegetable texture plays a role. Single meals only; no specific grant funding and no conflicts declared (full text).
  9. Kellingray L, Tapp HS, Saha S, Doleman JF, Narbad A, Mithen RF. Consumption of a diet rich in Brassica vegetables is associated with a reduced abundance of sulphate-reducing bacteria: A randomised crossover study. Mol Nutr Food Res. 2017;61(9):1600992. doi: 10.1002/mnfr.201600992.PubMedUsed to support: Randomized crossover trial in 10 healthy adults: a 2-week high-Brassica diet (six 84 g portions of broccoli, six 84 g portions of cauliflower and six 300 g broccoli and sweet potato soups) versus a low-Brassica diet (one portion each of broccoli and cauliflower). Lactobacilli did not change, while sulfate-reducing bacteria and several other taxa fell. No adverse effects were reported. Supported by the Danish Council for Strategic Research and the UK BBSRC; no conflicts declared.
  10. Connolly EL, Liu AH, Radavelli-Bagatini S, Shafaei A, Boyce MC, Wood LG, McCahon L, Koch H, Sim M, Hill CR, Parmenter BH, Bondonno NP, Devine A, Croft KD, Mithen R, Gan SK, Schultz CJ, Woodman RJ, Bondonno CP, Lewis JR, Hodgson JM, Blekkenhorst LC. Cruciferous vegetables lower blood pressure in adults with mildly elevated blood pressure in a randomized, controlled, crossover trial: the VEgetableS for vaScular hEaLth (VESSEL) study. BMC Med. 2024;22(1):353. doi: 10.1186/s12916-024-03577-8.PubMedUsed to support: Randomized controlled crossover trial in 18 adults (median age 68, 16 women) with mildly raised blood pressure: about 300 g a day of cruciferous vegetables as soup (40% broccoli, 25% cauliflower, 25% cabbage, 10% kale) versus root and squash vegetables, 2 weeks each, with participants not told which was active. 24-hour systolic pressure fell 2.5 mmHg and triglycerides 0.2 mmol/L more than with the control soup. No adverse events. Funded by Edith Cowan University and the Department of Health Western Australia.
  11. Connolly EL, Liu AH, Woodman RJ, Shafaei A, Wood LG, Mithen R, James AP, Schultz CJ, Gan SK, Bondonno CP, Lewis JR, Hodgson JM, Blekkenhorst LC. Cruciferous vegetables improve glycaemic control compared to root/squash vegetables in a randomized, controlled, crossover trial: The VEgetableS for vaScular hEaLth (VESSEL) study. Diabetes Obes Metab. 2025;27(8):4300-4310. doi: 10.1111/dom.16467.PubMedUsed to support: Prespecified secondary glycemic outcome of the VESSEL crossover trial in 18 non-diabetic adults with raised blood pressure, using flash glucose monitoring: glucose variability was 2.0% lower and the 2-hour post-meal glucose response 0.14 mmol/L lower with the crucifer soups than with root and squash soups, driven by dinner, while mean glucose did not differ (p = 0.411). The authors called the clinical impact uncertain.
  12. Eagles SK, Gross AS, McLachlan AJ. The Effects of Cruciferous Vegetable-Enriched Diets on Drug Metabolism: A Systematic Review and Meta-Analysis of Dietary Intervention Trials in Humans. Clin Pharmacol Ther. 2020;108(2):212-227. doi: 10.1002/cpt.1811.PubMedUsed to support: Systematic review and meta-analysis of 23 human diet intervention trials with drug metabolism end points, covering broccoli, Brussels sprouts, cabbage, cauliflower, radish and watercress: crucifer-enriched diets raised CYP1A2 activity by 20 to 40% and glutathione S-transferase alpha by 15 to 35%. People taking CYP1A2 or GST-alpha substrates could have altered drug exposure if they eat large or variable amounts.
  13. Galanty A, Grudzińska M, Paździora W, Służały P, Paśko P. Do Brassica Vegetables Affect Thyroid Function?-A Comprehensive Systematic Review. Int J Mol Sci. 2024;25(7):3988. doi: 10.3390/ijms25073988.PubMedUsed to support: Systematic review of 123 cell, animal and human studies on Brassica vegetables and thyroid function: most results cast doubt on antithyroid effects in humans and indicate that Brassica vegetables in the daily diet, particularly with adequate iodine intake, pose no adverse effects on thyroid function.
  14. National Institutes of Health, Office of Dietary Supplements. Iodine: Health Professional Fact Sheet. NIH Office of Dietary Supplements. 2026;Health professional fact sheet, accessed 2026..SourceUsed to support: Official NIH source (not PubMed-indexed). Foods high in goitrogens, which interfere with iodine uptake by the thyroid, include cruciferous vegetables such as cabbage, broccoli and cauliflower; this is a concern mainly in areas prone to iodine deficiency, and for most people with adequate iodine, reasonable amounts are not a concern.
  15. National Institutes of Health, Office of Dietary Supplements. Vitamin K: Health Professional Fact Sheet. NIH Office of Dietary Supplements. 2026;Health professional fact sheet, accessed 2026..SourceUsed to support: Official NIH source (not PubMed-indexed). Adequate Intakes for vitamin K are 120 micrograms for adult men and 90 micrograms for adult women. People taking warfarin and similar anticoagulants need a steady intake of vitamin K from food and supplements, because sudden changes can raise or lower the anticoagulant effect.
  16. National Institute of Diabetes and Digestive and Kidney Diseases. Eating, Diet, & Nutrition for Gas in the Digestive Tract. NIDDK, National Institutes of Health. 2021;Health information page, last reviewed June 2021, accessed 2026..SourceUsed to support: Official NIH source (not PubMed-indexed). Some carbohydrates are not fully digested in the stomach and small intestine and are broken down by bacteria in the large intestine, creating gas; foods that may lead to excess gas include cruciferous vegetables such as broccoli, cauliflower, collard greens and kale.