Home Ingredients Bergavit® (Bergamot Flavonoid Extract — Bionap)
CardiovascularMetabolic Health

Bergavit® (Bergamot Flavonoid Extract — Bionap)

Citrus bergamia
Evidence Level
Strong
1 Clinical Trial
3 Documented Benefits
4/5 Evidence Score

Bergavit® is a standardized bergamot (Citrus bergamia) fruit extract from Bionap, rich in a characteristic mix of flavonoids including neoeriocitrin, neohesperidin, and the statin-like compounds brutieridin and melitidin. Bergamot flavonoids are studied for supporting healthy cholesterol and triglyceride levels and cardiovascular health.

Studied Dose About 150 mg of bergamot flavonoids per day.
Active Compound Bergamot fruit flavonoid extract standardized to a defined flavonoid profile (including neoeriocitrin, neohesperidin, brutieridin, and melitidin).

Benefits

Healthy cholesterol levels

Bergamot flavonoids have reduced total and LDL cholesterol and triglycerides in clinical studies, while supporting HDL, making it a popular natural option for lipid management.

Supported by Trial 1

Small dense LDL

Research found bergamot lowered the small, dense LDL particles most associated with cardiovascular risk, a more refined benefit than total LDL alone.

Supported by Trial 1

Cardiovascular support

Through its lipid and antioxidant effects, bergamot is studied for supporting blood-vessel health and reducing markers of subclinical atherosclerosis.

Supported by Trial 1

Mechanism of action

1

HMG-CoA reductase modulation

Brutieridin and melitidin have a statin-like structure and can mildly inhibit HMG-CoA reductase, the enzyme that controls cholesterol synthesis.

2

Antioxidant flavonoids

The flavonoid mix reduces oxidative modification of LDL and supports endothelial function, contributing to the cardiovascular benefit.

Clinical trials

1
Bergamot and Plasma Lipids — Clinical Study
PubMed

Clinical study of standardized bergamot flavonoid extract on plasma lipids and atherogenic LDL. (Toth et al. 2015, Frontiers in Pharmacology)

Adults with elevated lipids.

Bergamot significantly reduced total and LDL cholesterol, triglycerides, and small dense LDL while improving markers of subclinical atherosclerosis.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — adverse effects in trials were minimal.
Mild heartburn or muscle cramps are rarely reported.
Citrus-sensitive individuals should start at a low dose.

Important Drug interactions

Statins — possible additive cholesterol lowering; monitor with your doctor.
Drugs metabolized by CYP enzymes — citrus flavonoids may interact; consult a pharmacist.
Diabetes medication — bergamot may affect blood sugar; monitor.

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Frequently asked questions about Bergavit® (Bergamot Flavonoid Extract — Bionap)

What is Bergavit?

Bergavit® is a standardized bergamot (Citrus bergamia) fruit extract from Bionap, rich in a characteristic mix of flavonoids including neoeriocitrin, neohesperidin, and the statin-like compounds brutieridin and melitidin.

What is Bergavit used for?

Bergavit is researched primarily for Cardiovascular and Metabolic Health. Bergamot flavonoids have reduced total and LDL cholesterol and triglycerides in clinical studies, while supporting HDL, making it a popular natural option for lipid management.

What is the recommended dosage of Bergavit?

The clinically studied dose is About 150 mg of bergamot flavonoids per day. Always follow the product label and check with a healthcare provider for personal advice.

Is Bergavit safe, and does it have side effects?

For most healthy adults, Bergavit is well tolerated at studied doses. Reported effects can include: Generally well-tolerated — adverse effects in trials were minimal. Mild heartburn or muscle cramps are rarely reported. It may also interact with some medications. Bergavit is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Bergavit interact with any medications?

Possible interactions include: Statins — possible additive cholesterol lowering; monitor with your doctor. Drugs metabolized by CYP enzymes — citrus flavonoids may interact; consult a pharmacist. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Bergavit?

NutraSmarts rates the evidence for Bergavit as Strong (4 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Toth PP, Patti AM, Nikolic D, et al. Bergamot Reduces Plasma Lipids, Atherogenic Small Dense LDL, and Subclinical Atherosclerosis in Subjects with Moderate Hypercholesterolemia. Front Pharmacol. 2015;6:299..PubMedUsed to support: Clinical study showing lipid and cardiovascular benefit.