SelectSIEVE® Bergamot (Citrus bergamia Extract — Roelmi HPC)

Citrus bergamia
Evidence Level
Moderate
1 Clinical Trial
3 Documented Benefits
3/5 Evidence Score

SelectSIEVE® Bergamot is a standardized bergamot (Citrus bergamia) extract from Roelmi HPC, rich in the citrus flavonoids unique to this Calabrian fruit. Bergamot polyphenols are studied for supporting healthy cholesterol, triglycerides, and metabolic health.

Studied Dose Commonly 500 to 1000 mg of bergamot extract per day.
Active Compound Bergamot (Citrus bergamia) extract standardized for flavonoids (brutieridin, melitidin, naringin).

Benefits

Healthy cholesterol and lipids

In a randomized trial, a bergamot extract improved plasma lipid profiles and reduced visceral fat in overweight adults with mild high cholesterol.

Metabolic support

Bergamot flavonoids are studied for supporting healthy blood sugar and metabolic markers.

Antioxidant defense

Bergamot polyphenols provide antioxidant activity that supports cardiovascular health.

Mechanism of action

1

Flavonoid lipid action

Bergamot's unique flavonoids are studied for supporting healthy cholesterol synthesis and clearance, similar in target to statin pathways.

2

Antioxidant action

Bergamot polyphenols scavenge free radicals and support blood-vessel health.

Clinical trials

1
Bergamot and Lipids/Visceral Fat — RCT
PubMed

Randomized placebo-controlled trial of a bergamot phytosome on visceral fat and lipids in overweight adults with mild high cholesterol. (Rondanelli et al. 2021, Phytotherapy Research)

Overweight adults with mild hypercholesterolemia.

Bergamot extract improved visceral fat and plasma lipid profiles versus placebo.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated.
Mild digestive upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Cholesterol medication (statins) — possible additive effect; consult your doctor.
Drugs affected by grapefruit-type citrus — consult a doctor.
Tell your doctor if you take cardiovascular medication.

Frequently asked questions about SelectSIEVE® Bergamot (Citrus bergamia Extract — Roelmi HPC)

What is SelectSIEVE Bergamot?

SelectSIEVE® Bergamot is a standardized bergamot (Citrus bergamia) extract from Roelmi HPC, rich in the citrus flavonoids unique to this Calabrian fruit. Bergamot polyphenols are studied for supporting healthy cholesterol, triglycerides, and metabolic health.

What is SelectSIEVE Bergamot used for?

SelectSIEVE Bergamot is researched primarily for Cardiovascular and Metabolic Health. In a randomized trial, a bergamot extract improved plasma lipid profiles and reduced visceral fat in overweight adults with mild high cholesterol.

What is the recommended dosage of SelectSIEVE Bergamot?

The clinically studied dose is Commonly 500 to 1000 mg of bergamot extract per day. Always follow the product label and check with a healthcare provider for personal advice.

Is SelectSIEVE Bergamot safe, and does it have side effects?

For most healthy adults, SelectSIEVE Bergamot is well tolerated at studied doses. Reported effects can include: Generally well-tolerated. Mild digestive upset is occasionally reported. It may also interact with some medications. SelectSIEVE Bergamot is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does SelectSIEVE Bergamot interact with any medications?

Possible interactions include: Cholesterol medication (statins) — possible additive effect; consult your doctor. Drugs affected by grapefruit-type citrus — consult a doctor. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for SelectSIEVE Bergamot?

NutraSmarts rates the evidence for SelectSIEVE Bergamot as Moderate (3 out of 5). It is backed by 1 clinical trial and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Rondanelli M, Peroni G, Riva A, et al. Bergamot phytosome improved visceral fat and plasma lipid profiles in overweight and obese class I subject with mild hypercholesterolemia: A randomized placebo controlled trial. Phytother Res. 2021;35(4):2045-2056..PubMedUsed to support: RCT supporting cholesterol and visceral-fat benefit of bergamot.