Oxxynea® (Fruit and Vegetable Polyphenols — Fytexia)

Evidence Level
Preliminary
1 Clinical Trial
3 Documented Benefits
1/5 Evidence Score

Oxxynea® is a concentrated blend of fruit and vegetable polyphenols from Fytexia, taken at 450 mg per day. In the one human study its polyphenols were absorbed into the bloodstream, which is the only thing measured in people so far. The claim that it provides the antioxidant value of several servings of produce is a marketing comparison, not a measured health effect, and no anti-inflammatory or cardiovascular outcome has been tested in humans.

Studied Dose 450 mg per day, the dose used in the single human study, a 10-person crossover pharmacokinetic trial.
Active Compound A 450 mg daily blend of polyphenols from concentrated fruits and vegetables, marketed by Fytexia.

Benefits

Antioxidant intake

Oxxynea concentrates the polyphenols of many fruits and vegetables, raising antioxidant intake and the circulating polyphenol metabolites that follow.

Cardiovascular positioning (no outcome measured)

Polyphenol-rich diets are broadly associated with blood-vessel health in the wider literature. No cardiovascular outcome has been measured for this blend itself; the single human study measured only that its polyphenols are absorbed.

Cellular protection

Polyphenols can act as antioxidants in laboratory tests. Whether this blend lowers oxidative stress in the body has not been measured; only its absorption has been.

Mechanism of action

1

Polyphenol metabolite exposure

After intake, the polyphenols are metabolized into compounds that circulate in the blood. The human study measured this absorption; it did not measure any antioxidant or vascular effect in the body.

2

Antioxidant defense

The polyphenols scavenge free radicals and support the body's own antioxidant systems.

Clinical trials

1
Polyphenol Concentrate and Metabolite Exposure — Study
PubMed

Human study measuring (poly)phenol metabolite exposure after a fruit and vegetable polyphenol concentrate. (Romain et al. 2022, Nutrients)

Healthy adults.

The concentrate produced measurable circulating polyphenol metabolites, confirming absorption of its antioxidant compounds; clinical outcome data are limited.

Side effects and drug interactions

Common Potential side effects

Generally well-tolerated — adverse effects are uncommon at normal doses.
Mild digestive upset is occasionally reported.
Discontinue if any unusual reaction occurs.

Important Drug interactions

Anticoagulants — polyphenols may have a mild additive effect; monitor.
Generally compatible with a healthy diet.
Tell your doctor if you take cardiovascular medication.

Frequently asked questions about Oxxynea® (Fruit and Vegetable Polyphenols — Fytexia)

What is Oxxynea?

Oxxynea® is a concentrated blend of fruit and vegetable polyphenols from Fytexia, taken at 450 mg per day. In the one human study its polyphenols were absorbed into the bloodstream, which is the only thing measured in people so far.

What is Oxxynea used for?

Oxxynea is researched primarily for Antioxidant. Oxxynea concentrates the polyphenols of many fruits and vegetables, raising antioxidant intake and the circulating polyphenol metabolites that follow.

What is the recommended dosage of Oxxynea?

The clinically studied dose is 450 mg per day, the dose used in the single human study, a 10-person crossover pharmacokinetic trial. Always follow the product label and check with a healthcare provider for personal advice.

Is Oxxynea safe, and does it have side effects?

Side effects and cautions reported for Oxxynea include: Generally well-tolerated — adverse effects are uncommon at normal doses. Mild digestive upset is occasionally reported. It may also interact with some medications. Oxxynea is not right for everyone, so check with a healthcare provider first if you are pregnant or breastfeeding, have a medical condition, or take prescription medication.

Does Oxxynea interact with any medications?

Possible interactions include: Anticoagulants — polyphenols may have a mild additive effect; monitor. Generally compatible with a healthy diet. If you take prescription medication, check with a pharmacist or doctor before using it.

How strong is the scientific evidence for Oxxynea?

NutraSmarts rates the evidence for Oxxynea as Preliminary (1 out of 5). It is backed by 1 study summary and 1 cited reference summarized on this page. A higher rating reflects more, larger, and better-designed human studies.

References(1 citations)

Evidence ratings on NutraSmarts are based on the totality of human clinical research, with emphasis on randomized controlled trials, meta-analyses, and systematic reviews. The references below directly support claims made throughout this page.

  1. Romain C, Bresciani L, Muralidharan J, et al. Exposure to (Poly)phenol Metabolites after a Fruit and Vegetable Supplement Intake: A Double-Blind, Cross-Over, Randomized Trial. Nutrients. 2022;14(22)..PubMedUsed to support: In a double-blind crossover trial, 10 healthy adults took 450 mg of the Oxxynea blend or placebo; its polyphenols appeared in blood and urine as measurable metabolites, with an estimated bioavailability of about 27%. The study confirmed absorption only. It did not measure any anti-inflammatory, cardiovascular, or antioxidant health outcome, and it was funded and co-authored by the manufacturer.